Project name: 6b9z:A
Status: done
submitted: 2019-03-21 13:12:32, status changed: 2019-03-21 13:24:17
Settings
Chain sequence(s)
|
A: DIQMTQSPIILLSSASVGDRRVTITCRASQDVNTAVAWYQQRTNGSSPRLLIIYSASFLYSSGVPSRFSGSSRSGTDFTTLTISSLQPEDEADYYCQQHYTTPPTFGAGTKVEEIKRTVAAPSVFIFPPSDDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.488
-
Maximal score value
-
2.5713
-
Average score
-
-0.6908
-
Total score value
-
-147.8363
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
A |
-2.3056 |
|
2 |
I |
A |
0.0000 |
|
3 |
Q |
A |
-1.8257 |
|
4 |
M |
A |
0.0000 |
|
5 |
T |
A |
-0.5848 |
|
6 |
Q |
A |
0.0000 |
|
7 |
S |
A |
0.4718 |
|
8 |
P |
A |
1.1645 |
|
9 |
I |
A |
2.3446 |
|
10 |
L |
A |
1.8267 |
|
11 |
L |
A |
0.8720 |
|
12 |
S |
A |
-0.2170 |
|
13 |
A |
A |
-0.8179 |
|
14 |
S |
A |
-0.7274 |
|
15 |
V |
A |
-0.0690 |
|
16 |
G |
A |
-0.8406 |
|
17 |
D |
A |
-1.8341 |
|
18 |
R |
A |
-2.3994 |
|
19 |
V |
A |
0.0000 |
|
20 |
T |
A |
-0.5916 |
|
21 |
I |
A |
0.0000 |
|
22 |
T |
A |
-0.5426 |
|
23 |
C |
A |
0.0000 |
|
24 |
R |
A |
-2.7186 |
|
25 |
A |
A |
0.0000 |
|
26 |
S |
A |
-2.2375 |
|
27 |
Q |
A |
-2.9378 |
|
28 |
D |
A |
-2.8754 |
|
29 |
V |
A |
0.0000 |
|
30 |
N |
A |
-1.9653 |
|
31 |
T |
A |
-0.9997 |
|
32 |
A |
A |
-0.4301 |
|
33 |
V |
A |
0.0000 |
|
34 |
A |
A |
0.8317 |
|
35 |
W |
A |
0.0000 |
|
36 |
Y |
A |
-0.2517 |
|
37 |
Q |
A |
0.0000 |
|
38 |
Q |
A |
-1.5667 |
|
39 |
R |
A |
-1.8046 |
|
40 |
T |
A |
-1.5736 |
|
41 |
N |
A |
-1.8131 |
|
42 |
G |
A |
-1.4852 |
|
43 |
S |
A |
-1.2768 |
|
44 |
P |
A |
-1.5415 |
|
45 |
R |
A |
-1.8188 |
|
46 |
L |
A |
-0.2225 |
|
47 |
L |
A |
0.0000 |
|
48 |
I |
A |
0.0000 |
|
49 |
Y |
A |
1.6649 |
|
50 |
S |
A |
0.5029 |
|
51 |
A |
A |
0.0000 |
|
52 |
S |
A |
0.9538 |
|
53 |
F |
A |
2.5713 |
|
54 |
L |
A |
2.0159 |
|
55 |
Y |
A |
1.5805 |
|
56 |
S |
A |
0.4534 |
|
57 |
G |
A |
-0.2374 |
|
58 |
V |
A |
0.0000 |
|
59 |
P |
A |
-0.2710 |
|
60 |
S |
A |
-0.3572 |
|
61 |
R |
A |
-0.7969 |
|
62 |
F |
A |
0.0000 |
|
63 |
S |
A |
0.0635 |
|
64 |
G |
A |
0.1442 |
|
65 |
S |
A |
-0.6035 |
|
66 |
R |
A |
-1.8007 |
|
67 |
S |
A |
-1.5256 |
|
68 |
G |
A |
-1.9969 |
|
69 |
T |
A |
-2.4472 |
|
70 |
D |
A |
-2.4236 |
|
71 |
F |
A |
0.0000 |
|
72 |
T |
A |
-0.8255 |
|
73 |
L |
A |
0.0000 |
|
74 |
T |
A |
-0.6421 |
|
75 |
I |
A |
0.0000 |
|
76 |
S |
A |
-1.5195 |
|
77 |
S |
A |
-1.2512 |
|
78 |
L |
A |
0.0000 |
|
79 |
Q |
A |
-1.0849 |
|
80 |
P |
A |
-1.5942 |
|
81 |
E |
A |
-1.9639 |
|
82 |
D |
A |
0.0000 |
|
83 |
E |
A |
0.0000 |
|
84 |
A |
A |
0.0000 |
|
85 |
D |
A |
-0.5744 |
|
86 |
Y |
A |
0.0000 |
|
87 |
Y |
A |
0.2548 |
|
88 |
C |
A |
0.0000 |
|
89 |
Q |
A |
0.6119 |
|
90 |
Q |
A |
0.0000 |
|
91 |
H |
A |
-0.4097 |
|
92 |
Y |
A |
0.2005 |
|
93 |
T |
A |
-0.3477 |
|
94 |
T |
A |
-0.5344 |
|
95 |
P |
A |
-0.5063 |
|
96 |
P |
A |
-0.3801 |
|
97 |
T |
A |
0.1508 |
|
98 |
F |
A |
1.5390 |
|
99 |
G |
A |
0.0000 |
|
100 |
A |
A |
0.6122 |
|
101 |
G |
A |
0.6576 |
|
102 |
T |
A |
0.0000 |
|
103 |
K |
A |
0.2693 |
|
104 |
V |
A |
0.0000 |
|
105 |
E |
A |
-0.6260 |
|
106 |
I |
A |
0.0000 |
|
107 |
K |
A |
-0.9820 |
|
108 |
R |
A |
-0.7293 |
|
109 |
T |
A |
-0.1081 |
|
110 |
V |
A |
0.1577 |
|
111 |
A |
A |
-0.3004 |
|
112 |
A |
A |
-0.3300 |
|
113 |
P |
A |
0.0000 |
|
114 |
S |
A |
-0.1106 |
|
115 |
V |
A |
0.0000 |
|
116 |
F |
A |
1.5196 |
|
117 |
I |
A |
1.3647 |
|
118 |
F |
A |
1.4738 |
|
119 |
P |
A |
-0.1952 |
|
120 |
P |
A |
-0.6875 |
|
121 |
S |
A |
-1.7683 |
|
122 |
D |
A |
-3.2362 |
|
123 |
E |
A |
-3.4194 |
|
124 |
Q |
A |
-2.5513 |
|
125 |
L |
A |
-2.6179 |
|
126 |
K |
A |
-3.1001 |
|
127 |
S |
A |
-2.0297 |
|
128 |
G |
A |
-1.3457 |
|
129 |
T |
A |
-1.0079 |
|
130 |
A |
A |
0.0000 |
|
131 |
S |
A |
0.0327 |
|
132 |
V |
A |
0.0000 |
|
133 |
V |
A |
0.7802 |
|
134 |
C |
A |
0.0000 |
|
135 |
L |
A |
0.6042 |
|
136 |
L |
A |
0.0000 |
|
137 |
N |
A |
-0.6598 |
|
138 |
N |
A |
-1.7315 |
|
139 |
F |
A |
0.0000 |
|
140 |
Y |
A |
0.0000 |
|
141 |
P |
A |
-1.8593 |
|
142 |
R |
A |
-2.9883 |
|
143 |
E |
A |
-3.2515 |
|
144 |
A |
A |
-2.3760 |
|
145 |
K |
A |
-2.4318 |
|
146 |
V |
A |
-1.1661 |
|
147 |
Q |
A |
-0.8827 |
|
148 |
W |
A |
0.0000 |
|
149 |
K |
A |
-0.7608 |
|
150 |
V |
A |
0.0000 |
|
151 |
D |
A |
-1.9758 |
|
152 |
N |
A |
-1.5753 |
|
153 |
A |
A |
-0.3770 |
|
154 |
L |
A |
0.4355 |
|
155 |
Q |
A |
-0.3463 |
|
156 |
S |
A |
-0.4874 |
|
157 |
G |
A |
-1.0117 |
|
158 |
N |
A |
-0.9866 |
|
159 |
S |
A |
-1.3705 |
|
160 |
Q |
A |
-2.1379 |
|
161 |
E |
A |
-2.0117 |
|
162 |
S |
A |
-1.1076 |
|
163 |
V |
A |
-0.5764 |
|
164 |
T |
A |
-1.0206 |
|
165 |
E |
A |
-1.7065 |
|
166 |
Q |
A |
0.0000 |
|
167 |
D |
A |
-2.3611 |
|
168 |
S |
A |
-2.2806 |
|
169 |
K |
A |
-2.7686 |
|
170 |
D |
A |
-2.3654 |
|
171 |
S |
A |
0.0000 |
|
172 |
T |
A |
0.0000 |
|
173 |
Y |
A |
0.0000 |
|
174 |
S |
A |
-1.0500 |
|
175 |
L |
A |
0.0000 |
|
176 |
S |
A |
-0.3424 |
|
177 |
S |
A |
0.0000 |
|
178 |
T |
A |
-0.5336 |
|
179 |
L |
A |
0.0000 |
|
180 |
T |
A |
-0.4817 |
|
181 |
L |
A |
-0.6295 |
|
182 |
S |
A |
-1.1905 |
|
183 |
K |
A |
-2.0586 |
|
184 |
A |
A |
-1.7457 |
|
185 |
D |
A |
-2.3104 |
|
186 |
Y |
A |
0.0000 |
|
187 |
E |
A |
-3.2509 |
|
188 |
K |
A |
-3.4880 |
|
189 |
H |
A |
-2.9257 |
|
190 |
K |
A |
-3.3115 |
|
191 |
V |
A |
-1.5663 |
|
192 |
Y |
A |
0.0000 |
|
193 |
A |
A |
0.0000 |
|
194 |
C |
A |
0.0000 |
|
195 |
E |
A |
-1.0658 |
|
196 |
V |
A |
0.0000 |
|
197 |
T |
A |
-1.2531 |
|
198 |
H |
A |
0.0000 |
|
199 |
Q |
A |
-1.8068 |
|
200 |
G |
A |
-0.5156 |
|
201 |
L |
A |
-0.2697 |
|
202 |
S |
A |
-0.4631 |
|
203 |
S |
A |
-0.4569 |
|
204 |
P |
A |
-0.6010 |
|
205 |
V |
A |
-0.1135 |
|
206 |
T |
A |
-0.4507 |
|
207 |
K |
A |
-0.3613 |
|
208 |
S |
A |
-0.3713 |
|
209 |
F |
A |
0.0000 |
|
210 |
N |
A |
-2.1061 |
|
211 |
R |
A |
-2.5774 |
|
212 |
G |
A |
-1.9942 |
|
213 |
E |
A |
-2.1831 |
|
214 |
C |
A |
-0.3992 |
|