Project name: 2WCV [mutate: EA112Y, EB112Y, EC112Y, ED112Y, EE112Y, EF112Y, EG112Y, EH112Y, EI112Y, EJ112Y]

Status: done

submitted: 2017-09-13 11:12:49, status changed: 2017-09-13 11:47:42
Settings
Chain sequence(s) A: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
C: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
B: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
E: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
D: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
G: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
F: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
I: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
H: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
J: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
Distance of aggregation 10 Å
Dynamic mode No
Mutated residues EA112Y, EB112Y, EC112Y, ED112Y, EE112Y, EF112Y, EG112Y, EH112Y, EI112Y, EJ112Y
Energy difference between WD and mutated (by FoldX) 4.30376 kcal/mol
Show buried residues

Minimal score value
-3.7173
Maximal score value
1.9046
Average score
-0.524
Total score value
-730.9416

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
1 M A 1.4699
2 L A 1.2603
3 K A -0.6434
4 T A -0.2068
5 I A 0.6701
6 S A 0.3480
7 P A 0.5483
8 L A 0.5338
9 I A 0.0000
10 S A -0.7339
11 P A -1.1126
12 E A -2.4394
13 L A 0.0000
14 L A -1.1468
15 K A -2.4379
16 V A 0.0000
17 L A 0.0000
18 A A -0.8463
19 E A -1.1283
20 M A 0.0000
21 G A 0.0000
22 H A 0.0000
23 G A -0.1056
24 D A 0.0000
25 E A -0.5856
26 I A 0.0000
27 I A 0.0000
28 F A 0.0000
29 S A 0.0000
30 D A 0.0000
31 A A -1.1624
32 H A -0.6224
33 F A 0.0000
34 P A 0.0000
35 A A 0.0000
36 H A -0.5815
37 S A -0.6710
38 M A -0.7909
39 G A -1.2964
40 P A -1.2350
41 Q A -0.9214
42 V A -0.3522
43 I A -0.8162
44 R A -1.2640
45 A A -1.0882
46 D A -2.1028
47 G A -1.4398
48 L A -0.6711
49 L A -0.4332
50 V A 0.0000
51 S A 0.0000
52 D A -0.7999
53 L A 0.0000
54 L A 0.0000
55 Q A -1.5786
56 A A 0.0000
57 I A 0.0000
58 I A -0.0975
59 P A -0.0737
60 L A 0.5173
61 F A 0.0000
62 E A -0.6115
63 L A -0.1497
64 D A 0.0000
65 S A -0.2247
66 Y A 0.2241
67 A A 0.2118
68 P A -0.0438
69 P A 0.0000
70 L A 0.0000
71 V A 0.0000
72 M A 0.0000
73 M A 0.0000
74 A A -0.2072
75 A A -0.7664
76 V A 0.0000
77 E A -1.4058
78 G A -0.8669
79 D A -0.6444
80 T A -0.7426
81 L A -0.9874
82 D A -2.1763
83 P A -2.1065
84 E A -3.1181
85 V A 0.0000
86 E A -2.4449
87 R A -3.3671
88 R A -2.6508
89 Y A 0.0000
90 R A -2.9016
91 N A -2.5252
92 A A -1.8617
93 L A 0.0000
94 S A -0.9828
95 L A -0.6608
98 P A -0.0547
99 C A 0.0963
100 P A -0.4095
101 D A -1.5574
102 I A 0.0000
103 I A 0.1592
104 R A -0.2371
105 I A 0.1020
106 N A -0.3070
107 R A 0.2747
108 F A 1.4616
109 A A 0.8269
110 F A 0.0000
111 Y A 0.6292
112 Y A 0.8348 mutated: EA112Y
113 R A -0.3596
114 A A 0.0000
115 Q A -1.5370
116 K A -2.0898
117 A A 0.0000
118 F A -0.7667
119 A A 0.0000
120 I A 0.0000
121 V A 0.0000
122 I A 0.0000
123 T A 0.0000
124 G A -1.3937
125 E A 0.0000
126 R A -2.1524
127 A A -1.9028
128 K A -1.9193
129 Y A 0.0000
130 G A 0.0000
131 N A 0.0000
132 I A 0.0000
133 L A 0.0000
134 L A 0.0000
135 K A -0.3842
136 K A 0.0000
137 G A 0.0000
138 V A -0.3301
139 T A -0.3926
140 P A -0.6014
1 M B 1.3235
2 L B 0.9624
3 K B -0.7822
4 T B -0.2571
5 I B 0.5871
6 S B 0.2609
7 P B 0.5131
8 L B 0.5052
9 I B 0.0000
10 S B -0.6962
11 P B -1.0710
12 E B -2.3020
13 L B 0.0000
14 L B -1.1095
15 K B -2.3501
16 V B 0.0000
17 L B 0.0000
18 A B -0.6536
19 E B -1.1229
20 M B 0.0000
21 G B 0.0000
22 H B -0.2454
23 G B -0.4618
24 D B 0.0000
25 E B -0.6300
26 I B 0.0000
27 I B 0.0000
28 F B 0.0000
29 S B 0.0000
30 D B 0.0000
31 A B -1.1364
32 H B 0.0000
33 F B 0.0000
34 P B 0.0000
35 A B 0.0000
36 H B -0.6343
37 S B -0.7713
38 M B -0.8509
39 G B -1.2449
40 P B -1.2284
41 Q B -1.0129
42 V B -0.4002
43 I B -0.8385
44 R B -1.2932
45 A B -1.0676
46 D B -2.0638
47 G B -1.3619
48 L B -0.3342
49 L B -0.2549
50 V B 0.0000
51 S B -1.1698
52 D B -0.7336
53 L B 0.0000
54 L B 0.0000
55 Q B -1.6730
56 A B -0.5371
57 I B 0.0000
58 I B 0.0000
59 P B -0.4015
60 L B 0.1415
61 F B 0.0000
62 E B -0.8045
63 L B -0.2513
64 D B 0.0000
65 S B -0.0833
66 Y B 0.2831
67 A B 0.1604
68 P B -0.3461
69 P B 0.0000
70 L B 0.0000
71 V B 0.0000
72 M B 0.0000
73 M B 0.0000
74 A B 0.0000
75 A B -0.6444
76 V B -0.4067
77 E B -1.4420
78 G B -1.3450
79 D B -1.4835
80 T B -1.3784
81 L B -1.1312
82 D B -2.4449
83 P B -2.0307
84 E B -2.7283
85 V B 0.0000
86 E B -2.5307
87 R B -3.6572
88 R B -2.7912
89 Y B 0.0000
90 R B -3.1742
91 N B -2.7115
92 A B 0.0000
93 L B 0.0000
94 S B -1.1181
95 L B -0.5062
96 Q B -1.1063
97 A B -0.5519
98 P B -0.9230
99 C B -0.9919
100 P B -1.1337
101 D B -1.9929
102 I B 0.0000
103 I B -0.6711
104 R B -0.5018
105 I B 0.0000
106 N B -0.1419
107 R B 0.2863
108 F B 1.2515
109 A B 0.0000
110 F B 0.0000
111 Y B 0.0000
112 Y B 0.1262 mutated: EB112Y
113 R B -0.5842
114 A B 0.0000
115 Q B -1.6248
116 K B -2.3565
117 A B 0.0000
118 F B 0.0000
119 A B 0.0000
120 I B 0.0000
121 V B 0.0000
122 I B 0.0000
123 T B 0.0000
124 G B -1.2809
125 E B 0.0000
126 R B -2.0708
127 A B -1.5257
128 K B -1.5868
129 Y B 0.0000
130 G B 0.0000
131 N B 0.0000
132 I B 0.0000
133 L B 0.0000
134 L B 0.0000
135 K B -0.4333
136 K B 0.0000
137 G B 0.0000
138 V B -0.3026
139 T B -0.4603
140 P B -0.5589
1 M C 1.4269
2 L C 1.1337
3 K C -0.7080
4 T C -0.2444
5 I C 0.6112
6 S C 0.4046
7 P C 0.6156
8 L C 0.6845
9 I C 0.0000
10 S C -0.6535
11 P C -1.0577
12 E C -2.2844
13 L C 0.0000
14 L C -1.1190
15 K C -2.3773
16 V C 0.0000
17 L C 0.0000
18 A C -0.7952
19 E C -1.0596
20 M C 0.0000
21 G C 0.0000
22 H C 0.0000
23 G C -0.1637
24 D C 0.0000
25 E C -0.7196
26 I C 0.0000
27 I C 0.0000
28 F C 0.0000
29 S C 0.0000
30 D C 0.0000
31 A C -1.0686
32 H C -0.6071
33 F C 0.0000
34 P C 0.0000
35 A C 0.0000
36 H C -0.5852
37 S C -0.9206
38 M C 0.0000
39 G C -1.4441
40 P C -1.2632
41 Q C -0.7932
42 V C -0.2603
43 I C -0.7209
44 R C -1.2118
45 A C -1.0194
46 D C -2.0396
47 G C -1.1728
48 L C -0.5703
49 L C -0.3042
50 V C 0.0000
51 S C -0.8074
52 D C -0.6981
53 L C 0.0000
54 L C 0.0000
55 Q C -1.4120
56 A C -0.3472
57 I C 0.0000
58 I C -0.1289
59 P C -0.0897
60 L C 0.5012
61 F C 0.0000
62 E C -0.7858
63 L C -0.3090
64 D C 0.0000
65 S C -0.1586
66 Y C 0.0619
67 A C 0.0060
68 P C -0.3896
69 P C 0.0000
70 L C 0.0000
71 V C 0.0000
72 M C 0.0000
73 M C 0.0000
74 A C -0.6357
75 A C -0.9945
76 V C -1.2833
77 E C -2.4779
78 G C -1.6892
79 D C -1.1041
80 T C -0.7997
81 L C -0.6882
82 D C -2.0489
83 P C -2.1236
84 E C -3.0111
85 V C 0.0000
86 E C -2.3387
87 R C -3.4106
88 R C -2.4953
89 Y C 0.0000
90 R C -2.3460
91 N C -2.3782
92 A C 0.0000
93 L C 0.0000
94 S C -0.9140
97 A C -0.0999
98 P C -0.6828
99 C C -0.8388
100 P C -1.0092
101 D C -1.7402
102 I C 0.0000
103 I C 0.2032
104 R C -0.2835
105 I C -0.4450
106 N C -1.5048
107 R C -1.1189
108 F C -0.6724
109 A C -0.5099
110 F C 0.0000
111 Y C -0.8685
112 Y C -0.8595 mutated: EC112Y
113 R C -1.4818
114 A C 0.0000
115 Q C -2.2047
116 K C -2.5228
117 A C 0.0000
118 F C -0.8723
119 A C 0.0000
120 I C 0.0000
121 V C 0.0000
122 I C 0.0000
123 T C 0.0000
124 G C 0.0000
125 E C 0.0000
126 R C -1.8839
127 A C -1.5229
128 K C -1.2167
129 Y C -0.6314
130 G C 0.0000
131 N C 0.0000
132 I C 0.0000
133 L C 0.0000
134 L C 0.0000
135 K C -0.4978
136 K C 0.0000
137 G C 0.0000
138 V C -0.4046
139 T C -0.5630
140 P C -0.7530
1 M D 1.3770
2 L D 1.1057
3 K D -0.7081
4 T D -0.2075
5 I D 0.6569
6 S D 0.2056
7 P D 0.4179
8 L D 0.2789
9 I D 0.0000
10 S D -0.7287
11 P D -1.1275
12 E D -2.4165
13 L D 0.0000
14 L D -1.1995
15 K D -2.4185
16 V D 0.0000
17 L D 0.0000
18 A D -0.8297
19 E D -1.1411
20 M D 0.0000
21 G D 0.0000
22 H D 0.0000
23 G D -0.3715
24 D D 0.0000
25 E D -0.6284
26 I D 0.0000
27 I D 0.0000
28 F D 0.0000
29 S D 0.0000
30 D D 0.0000
31 A D -1.0573
32 H D 0.0000
33 F D 0.0000
34 P D 0.0000
35 A D 0.0000
36 H D -0.5940
37 S D -0.7916
38 M D -0.9491
39 G D -1.3206
40 P D -1.2568
41 Q D -0.9000
42 V D -0.4703
43 I D -0.7421
44 R D -1.2965
45 A D -0.9499
46 D D -1.9606
47 G D -1.2856
48 L D -0.5131
49 L D -0.1654
50 V D 0.0000
51 S D 0.0000
52 D D -1.2445
53 L D 0.0000
54 L D 0.0000
55 Q D -1.5558
56 A D -0.4546
57 I D 0.0000
58 I D -0.1233
59 P D -0.1382
60 L D 0.4740
61 F D 0.0000
62 E D -0.5045
63 L D -0.0798
64 D D 0.0000
65 S D -0.0809
66 Y D 0.2077
67 A D -0.0325
68 P D -0.3183
69 P D 0.0000
70 L D 0.0000
71 V D 0.0000
72 M D 0.0000
73 M D 0.0000
74 A D -0.5854
75 A D -1.0695
76 V D -1.0697
77 E D -2.0441
78 G D -1.5003
79 D D -1.4539
80 T D -0.9960
81 L D -1.1392
82 D D -2.5495
83 P D -2.4080
84 E D -3.2309
85 V D 0.0000
86 E D -2.4571
87 R D -3.5902
88 R D -2.8090
89 Y D 0.0000
90 R D -2.3393
91 N D -2.2284
92 A D 0.0000
93 L D 0.0000
94 S D -0.8964
95 L D -0.3367
96 Q D -0.9178
97 A D -0.5384
98 P D -0.8339
99 C D -0.8426
100 P D -1.0365
101 D D -1.8037
102 I D 0.0000
103 I D -0.0096
104 R D -0.4066
105 I D -0.4176
106 N D -1.0688
107 R D -0.4727
108 F D 0.1416
109 A D -0.1977
110 F D 0.0000
111 Y D -0.3118
112 Y D -0.5111 mutated: ED112Y
113 R D -0.9934
114 A D 0.0000
115 Q D -1.9236
116 K D -2.3419
117 A D 0.0000
118 F D 0.0000
119 A D 0.0000
120 I D 0.0000
121 V D 0.0000
122 I D 0.0000
123 T D 0.0000
124 G D 0.0000
125 E D 0.0000
126 R D -1.9738
127 A D -1.6518
128 K D -1.5788
129 Y D 0.0000
130 G D 0.0000
131 N D 0.0000
132 I D 0.0000
133 L D 0.0000
134 L D 0.0000
135 K D -0.3362
136 K D 0.0000
137 G D 0.0000
138 V D -0.2707
139 T D -0.4030
140 P D -0.5762
1 M E 1.3982
2 L E 1.0886
3 K E -0.7344
4 T E -0.2660
5 I E 0.5892
6 S E 0.1831
7 P E 0.5448
8 L E 0.5516
9 I E 0.0000
10 S E -0.6892
11 P E -1.1127
12 E E -2.4380
13 L E 0.0000
14 L E -1.2220
15 K E -2.4294
16 V E 0.0000
17 L E 0.0000
18 A E -0.8208
19 E E -1.1298
20 M E 0.0000
21 G E 0.0000
22 H E 0.0000
23 G E -0.0870
24 D E 0.0000
25 E E -0.5737
26 I E 0.0000
27 I E 0.0000
28 F E 0.0000
29 S E 0.0000
30 D E 0.0000
31 A E -1.0775
32 H E -0.6329
33 F E 0.0000
34 P E 0.0000
35 A E 0.0000
36 H E -0.5927
37 S E -0.7969
38 M E 0.0000
39 G E -1.1299
40 P E -1.0924
41 Q E -0.9960
42 V E -0.3552
43 I E -0.8131
44 R E -1.2629
45 A E -1.1207
46 D E -2.0855
47 G E -1.2081
48 L E -0.6055
49 L E -0.2124
50 V E 0.0000
51 S E -0.9646
52 D E -0.6736
53 L E 0.0000
54 L E 0.0000
55 Q E -1.1464
56 A E 0.0000
57 I E 0.0000
58 I E 0.0000
59 P E 0.1359
60 L E 0.4482
61 F E 0.0000
62 E E -0.6268
63 L E -0.1448
64 D E 0.0000
65 S E -0.1402
66 Y E 0.1614
67 A E -0.0680
68 P E 0.0000
69 P E 0.0000
70 L E 0.0000
71 V E 0.0000
72 M E 0.0000
73 M E 0.0000
74 A E -0.2709
75 A E -0.6122
76 V E -0.6704
77 E E -1.9895
78 G E -1.4071
79 D E -1.0129
80 T E -0.6744
81 L E -0.5514
82 D E -1.7480
83 P E -2.0515
84 E E -3.1296
85 V E 0.0000
86 E E -2.5276
87 R E -3.5997
88 R E -2.8079
89 Y E 0.0000
90 R E -2.4292
91 N E -2.1971
92 A E 0.0000
93 L E 0.0000
94 S E -0.2315
95 L E 1.0272
97 A E 0.4316
98 P E -0.3698
99 C E 0.0000
100 P E -0.9952
101 D E -1.9825
102 I E 0.0000
103 I E 0.0000
104 R E -0.6912
105 I E 0.0000
106 N E -0.1099
107 R E 0.0000
108 F E -0.2390
109 A E 0.0000
110 F E 0.0000
111 Y E 0.0000
112 Y E -0.5959 mutated: EE112Y
113 R E -0.9822
114 A E 0.0000
115 Q E -1.3862
116 K E -1.9636
117 A E 0.0000
118 F E -0.6853
119 A E 0.0000
120 I E 0.0000
121 V E 0.0000
122 I E 0.0000
123 T E 0.0000
124 G E -1.2438
125 E E 0.0000
126 R E -1.9104
127 A E -1.4481
128 K E -1.1632
129 Y E 0.0000
130 G E 0.0000
131 N E 0.0000
132 I E 0.0000
133 L E 0.0000
134 L E 0.0000
135 K E -0.3679
136 K E 0.0000
137 G E 0.0000
138 V E -0.0572
139 T E -0.2729
140 P E -0.5758
1 M F 1.3982
2 L F 1.1243
3 K F -0.7422
4 T F -0.3193
5 I F 0.4495
6 S F 0.2487
7 P F 0.4594
8 L F 0.4239
9 I F 0.0000
10 S F -0.7277
11 P F -1.0849
12 E F -2.4957
13 L F 0.0000
14 L F -1.1931
15 K F -2.4031
16 V F 0.0000
17 L F 0.0000
18 A F -0.8344
19 E F -1.1729
20 M F 0.0000
21 G F 0.0000
22 H F 0.0000
23 G F -0.0790
24 D F 0.0000
25 E F 0.0000
26 I F 0.0000
27 I F 0.0000
28 F F 0.0000
29 S F 0.0000
30 D F 0.0000
31 A F -1.0864
32 H F 0.0000
33 F F 0.0000
34 P F 0.0000
35 A F 0.0000
36 H F -0.6834
37 S F -0.9567
38 M F 0.0000
39 G F -1.4648
40 P F -1.3540
41 Q F -0.9439
42 V F -0.3285
43 I F -0.8000
44 R F -1.4409
45 A F -1.0333
46 D F -2.0326
47 G F -1.3339
48 L F -0.5350
49 L F -0.2733
50 V F 0.0000
51 S F -1.1223
52 D F -0.9189
53 L F 0.0000
54 L F 0.0000
55 Q F -1.5718
56 A F 0.0000
57 I F 0.0000
58 I F -0.1006
59 P F -0.0846
60 L F 0.5133
61 F F 0.0000
62 E F -0.6186
63 L F -0.1308
64 D F 0.0000
65 S F -0.0075
66 Y F 0.3757
67 A F 0.0486
68 P F -0.2043
69 P F 0.0000
70 L F 0.0000
71 V F 0.0000
72 M F 0.0000
73 M F 0.0000
74 A F -0.5814
75 A F -1.2545
76 V F 0.0000
77 E F -2.7111
78 G F -1.8760
79 D F -1.6932
80 T F -1.1541
81 L F -1.1827
82 D F -2.6482
83 P F -2.4300
84 E F -3.2718
85 V F 0.0000
86 E F -2.4412
87 R F -3.5141
88 R F -2.5911
89 Y F 0.0000
90 R F -2.6560
91 N F -2.5508
92 A F 0.0000
93 L F 0.0000
94 S F -1.2843
95 L F -1.5030
96 Q F -1.6052
97 A F -0.6730
98 P F -0.4466
99 C F -0.2603
100 P F -0.5968
101 D F -1.4507
102 I F -0.3685
103 I F 0.3008
104 R F -0.1610
105 I F -0.1954
106 N F -1.1505
107 R F 0.0000
108 F F 0.0455
109 A F 0.1518
110 F F 0.0000
111 Y F -0.0988
112 Y F 0.3182 mutated: EF112Y
113 R F -0.6496
114 A F 0.0000
115 Q F -1.8655
116 K F -2.2238
117 A F 0.0000
118 F F 0.0000
119 A F 0.0000
120 I F 0.0000
121 V F 0.0000
122 I F 0.0000
123 T F 0.0000
124 G F 0.0000
125 E F 0.0000
126 R F -2.0252
127 A F -1.7780
128 K F -1.7341
129 Y F 0.0000
130 G F 0.0000
131 N F 0.0000
132 I F 0.0000
133 L F 0.0000
134 L F 0.0000
135 K F -0.3212
136 K F 0.0000
137 G F 0.0000
138 V F -0.2882
139 T F -0.4139
140 P F -0.6257
1 M G 1.4540
2 L G 1.2018
3 K G -0.7014
4 T G -0.2625
5 I G 0.5672
6 S G 0.2336
7 P G 0.5716
8 L G 0.5284
9 I G 0.0000
10 S G -0.5726
11 P G -0.8622
12 E G -1.9541
13 L G 0.0000
14 L G -0.9841
15 K G -2.2269
16 V G 0.0000
17 L G 0.0000
18 A G -0.6238
19 E G -1.0958
20 M G 0.0000
21 G G 0.0000
22 H G -0.2095
23 G G -0.2309
24 D G 0.0000
25 E G -0.6599
26 I G 0.0000
27 I G 0.0000
28 F G 0.0000
29 S G 0.0000
30 D G 0.0000
31 A G -1.1252
32 H G -0.6298
33 F G 0.0000
34 P G 0.0000
35 A G 0.0000
36 H G -0.7001
37 S G -0.9014
38 M G 0.0000
39 G G -1.3710
40 P G -1.3063
41 Q G -0.9056
42 V G -0.5336
43 I G 0.0000
44 R G -1.3273
45 A G -1.0594
46 D G -2.0511
47 G G -1.3526
48 L G -0.5322
49 L G -0.3541
50 V G 0.0000
51 S G -1.1290
52 D G -0.7184
53 L G 0.0000
54 L G 0.0000
55 Q G -1.5212
56 A G 0.0000
57 I G 0.0000
58 I G 0.0000
59 P G -0.3416
60 L G 0.3346
61 F G 0.0000
62 E G -0.6173
63 L G -0.1159
64 D G 0.0000
65 S G -0.0815
66 Y G 0.3137
67 A G 0.0502
68 P G -0.3674
69 P G 0.0000
70 L G 0.0000
71 V G 0.0000
72 M G 0.0000
73 M G 0.0000
74 A G -0.2300
75 A G -0.8358
76 V G -0.9480
77 E G -2.0425
78 G G -1.4820
79 D G -1.2208
80 T G -0.7902
81 L G -0.6693
82 D G -1.8601
83 P G -2.0677
84 E G -3.1198
85 V G 0.0000
86 E G -2.4919
87 R G -3.6396
88 R G -2.7910
89 Y G 0.0000
90 R G -2.9237
91 N G -2.5613
92 A G 0.0000
93 L G 0.0000
94 S G -1.0760
95 L G -0.4558
96 Q G -1.1088
97 A G -0.5739
98 P G -0.8395
99 C G -0.9056
100 P G -1.0706
101 D G -1.9188
102 I G 0.0000
103 I G -0.0995
104 R G -0.5287
105 I G 0.1272
106 N G -0.0342
107 R G 0.5414
108 F G 1.8298
109 A G 0.6837
110 F G 0.0000
111 Y G 0.3390
112 Y G 0.1479 mutated: EG112Y
113 R G -0.8468
114 A G 0.0000
115 Q G -2.0023
116 K G -2.4609
117 A G 0.0000
118 F G 0.0000
119 A G 0.0000
120 I G 0.0000
121 V G 0.0000
122 I G 0.0000
123 T G 0.0000
124 G G 0.0000
125 E G 0.0000
126 R G -2.0042
127 A G -1.6143
128 K G -1.3563
129 Y G 0.0000
130 G G 0.0000
131 N G 0.0000
132 I G 0.0000
133 L G 0.0000
134 L G 0.0000
135 K G -0.3936
136 K G 0.0000
137 G G 0.0000
138 V G -0.2819
139 T G -0.4266
140 P G -0.6057
1 M H 1.2798
2 L H 0.7417
3 K H -0.9062
4 T H -0.3658
5 I H 0.5129
6 S H 0.2568
7 P H 0.6721
8 L H 1.0180
9 I H 0.0000
10 S H -0.6148
11 P H -1.1218
12 E H -2.4290
13 L H 0.0000
14 L H -1.1858
15 K H -2.4087
16 V H 0.0000
17 L H 0.0000
18 A H -0.8052
19 E H -1.0886
20 M H 0.0000
21 G H 0.0000
22 H H 0.0000
23 G H -0.1513
24 D H 0.0000
25 E H 0.0000
26 I H 0.0000
27 I H 0.0000
28 F H 0.0000
29 S H 0.0000
30 D H 0.0000
31 A H -0.9885
32 H H -0.6119
33 F H 0.0000
34 P H 0.0000
35 A H 0.0000
36 H H -0.6575
37 S H -0.7593
38 M H 0.0000
39 G H -1.2342
40 P H -1.2250
41 Q H -1.0886
42 V H -0.3902
43 I H -0.7921
44 R H -1.2099
45 A H -0.8950
46 D H -1.7974
47 G H -1.0409
48 L H -0.3192
49 L H -0.2662
50 V H 0.0000
51 S H -1.0916
52 D H -0.7560
53 L H 0.0000
54 L H 0.0000
55 Q H -1.5100
56 A H 0.0000
57 I H 0.0000
58 I H 0.0000
59 P H -0.2552
60 L H 0.5284
61 F H 0.0000
62 E H -0.5953
63 L H -0.1990
64 D H 0.0000
65 S H -0.2719
66 Y H 0.0134
67 A H -0.1462
68 P H 0.0000
69 P H 0.0000
70 L H 0.0000
71 V H 0.0000
72 M H 0.0000
73 M H 0.0000
74 A H -0.3452
75 A H -0.7441
76 V H -0.7928
77 E H -2.1076
78 G H -1.5795
79 D H -1.2602
80 T H -0.7723
81 L H -0.5558
82 D H -1.9044
83 P H -2.0308
84 E H -2.9659
85 V H 0.0000
86 E H -2.5244
87 R H -3.5128
88 R H -2.6173
89 Y H 0.0000
90 R H -2.5095
91 N H -2.3295
92 A H 0.0000
93 L H 0.0000
94 S H -0.9153
95 L H -0.4316
96 Q H -0.8990
97 A H -0.4820
98 P H -0.8370
99 C H 0.0000
100 P H -1.1672
101 D H -2.2655
102 I H 0.0000
103 I H 0.0000
104 R H -0.6333
105 I H 0.0000
106 N H -0.3369
107 R H -0.3172
108 F H -0.1536
109 A H 0.0000
110 F H 0.0000
111 Y H 0.0000
112 Y H 0.0000 mutated: EH112Y
113 R H -0.9510
114 A H 0.0000
115 Q H -1.8092
116 K H -2.0847
117 A H 0.0000
118 F H -0.6530
119 A H 0.0000
120 I H 0.0000
121 V H 0.0000
122 I H 0.0000
123 T H 0.0000
124 G H 0.0000
125 E H 0.0000
126 R H -1.9287
127 A H -1.5215
128 K H -1.1640
129 Y H 0.0000
130 G H 0.0000
131 N H 0.0000
132 I H 0.0000
133 L H 0.0000
134 L H 0.0000
135 K H -0.3026
136 K H 0.0000
137 G H 0.0000
138 V H -0.4091
139 T H -0.4154
140 P H -0.6254
1 M I 1.3104
2 L I 0.9429
3 K I -0.8230
4 T I -0.3222
5 I I 0.4732
6 S I 0.2062
7 P I 0.4174
8 L I 0.5158
9 I I 0.0000
10 S I -0.6690
11 P I -1.0612
12 E I -2.3411
13 L I 0.0000
14 L I -1.0526
15 K I -2.3456
16 V I 0.0000
17 L I 0.0000
18 A I -0.8230
19 E I -1.1243
20 M I 0.0000
21 G I 0.0000
22 H I -0.2412
23 G I -0.1979
24 D I 0.0000
25 E I -0.6386
26 I I 0.0000
27 I I 0.0000
28 F I 0.0000
29 S I 0.0000
30 D I 0.0000
31 A I -1.1227
32 H I -0.6826
33 F I 0.0000
34 P I 0.0000
35 A I 0.0000
36 H I -0.5984
37 S I -0.8129
38 M I -0.8814
39 G I -1.4002
40 P I -1.2736
41 Q I -0.7948
42 V I -0.4541
43 I I -0.7661
44 R I -1.3830
45 A I -1.0098
46 D I -2.0154
47 G I -1.3288
48 L I -0.3163
49 L I -0.1180
50 V I 0.0000
51 S I 0.0000
52 D I -0.6094
53 L I 0.0000
54 L I 0.0000
55 Q I -1.0482
56 A I 0.0000
57 I I 0.0000
58 I I -0.0772
59 P I -0.1528
60 L I 0.4346
61 F I 0.0000
62 E I -0.6635
63 L I -0.2127
64 D I 0.0000
65 S I -0.2576
66 Y I 0.1159
67 A I -0.0382
68 P I -0.2709
69 P I -0.3593
70 L I 0.0000
71 V I 0.0000
72 M I 0.0000
73 M I 0.0000
74 A I -0.3048
75 A I -0.8919
76 V I 0.0000
77 E I -1.5846
78 G I -0.8530
79 D I -0.7695
80 T I -0.8019
81 L I -1.2935
82 D I -2.7923
83 P I -2.5580
84 E I -3.1833
85 V I 0.0000
86 E I -2.7130
87 R I -3.7173
88 R I -2.6597
89 Y I 0.0000
90 R I -2.4414
91 N I -2.4608
92 A I 0.0000
93 L I 0.0000
94 S I -0.9246
95 L I -0.3453
96 Q I -1.0657
97 A I -0.6093
98 P I -0.8321
99 C I 0.0000
100 P I -0.6873
101 D I -0.8898
102 I I 0.0000
103 I I 0.1848
104 R I -0.0235
105 I I 0.1193
106 N I -0.2532
107 R I 0.1049
108 F I 1.1709
109 A I 0.5879
110 F I 0.0000
111 Y I 0.3614
112 Y I 0.5788 mutated: EI112Y
113 R I -0.6380
114 A I 0.0000
115 Q I -1.8424
116 K I -2.2692
117 A I 0.0000
118 F I 0.0000
119 A I 0.0000
120 I I 0.0000
121 V I 0.0000
122 I I 0.0000
123 T I 0.0000
124 G I 0.0000
125 E I 0.0000
126 R I -2.0707
127 A I -1.7379
128 K I -1.6232
129 Y I 0.0000
130 G I 0.0000
131 N I 0.0000
132 I I 0.0000
133 L I 0.0000
134 L I 0.0000
135 K I -0.4361
136 K I 0.0000
137 G I 0.0000
138 V I -0.4238
139 T I -0.4583
140 P I -0.5838
1 M J 1.3116
2 L J 0.8562
3 K J -0.8513
4 T J -0.3226
5 I J 0.5681
6 S J 0.1742
7 P J 0.5419
8 L J 0.7487
9 I J 0.0000
10 S J -0.6595
11 P J -1.1148
12 E J -2.4240
13 L J 0.0000
14 L J -1.1766
15 K J -2.4256
16 V J 0.0000
17 L J 0.0000
18 A J -0.8245
19 E J -1.1591
20 M J 0.0000
21 G J 0.0000
22 H J 0.0000
23 G J -0.4646
24 D J 0.0000
25 E J -0.5994
26 I J 0.0000
27 I J 0.0000
28 F J 0.0000
29 S J 0.0000
30 D J 0.0000
31 A J -1.0837
32 H J -0.6617
33 F J 0.0000
34 P J 0.0000
35 A J 0.0000
36 H J -0.5540
37 S J -0.7871
38 M J 0.0000
39 G J -1.3589
40 P J -1.1968
41 Q J -0.8696
42 V J -0.2937
43 I J -0.8181
44 R J -1.3958
45 A J -1.1293
46 D J -2.1183
47 G J -1.2297
48 L J -0.4604
49 L J -0.2862
50 V J 0.0000
51 S J 0.0000
52 D J -0.7100
53 L J 0.0000
54 L J 0.0000
55 Q J -1.2820
56 A J 0.0000
57 I J 0.0000
58 I J 0.0000
59 P J -0.0441
60 L J 0.7519
61 F J 0.0000
62 E J -0.5667
63 L J 0.0000
64 D J 0.0000
65 S J -0.1710
66 Y J -0.0579
67 A J -0.3056
68 P J -0.4864
69 P J -0.5532
70 L J 0.0000
71 V J 0.0000
72 M J 0.0000
73 M J 0.0000
74 A J -0.1656
75 A J -0.6642
76 V J -0.4408
77 E J -1.9239
78 G J 0.0000
79 D J -0.9213
80 T J -1.1440
81 L J -0.9303
82 D J -2.4448
83 P J -2.3676
84 E J -3.0553
85 V J 0.0000
86 E J 0.0000
87 R J -3.4260
88 R J -2.5647
89 Y J 0.0000
90 R J -2.4163
91 N J -2.0128
92 A J 0.0000
93 L J 0.0000
94 S J -0.5662
95 L J 0.2830
96 Q J -0.6824
97 A J -0.3864
98 P J -0.2847
99 C J -0.6531
100 P J -1.0515
101 D J -1.8453
102 I J 0.0000
103 I J 0.0000
104 R J -0.3636
105 I J 0.0000
106 N J 0.0066
107 R J 0.4548
108 F J 1.9046
109 A J 0.0000
110 F J 0.0000
111 Y J 0.3817
112 Y J 0.3580 mutated: EJ112Y
113 R J -0.4009
114 A J 0.0000
115 Q J -1.9589
116 K J -2.2387
117 A J 0.0000
118 F J -0.7461
119 A J 0.0000
120 I J 0.0000
121 V J 0.0000
122 I J 0.0000
123 T J 0.0000
124 G J 0.0000
125 E J 0.0000
126 R J -1.9679
127 A J -1.6379
128 K J -1.4323
129 Y J -0.7282
130 G J 0.0000
131 N J 0.0000
132 I J 0.0000
133 L J 0.0000
134 L J 0.0000
135 K J -0.4828
136 K J -0.5020
137 G J 0.0000
138 V J -0.3682
139 T J -0.3950
140 P J -0.6995

 

Laboratory of Theory of Biopolymers 2015