Project name: bsakan

Chain sequence(s)	A: DTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSSLHTLFGDELCKVASLRRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMRREKVLTSSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.2881
• Maximal score value: 1.0831
• Average score: -1.177
• Total score value: -686.1876

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-2.2105
2	T	A	-1.8328
3	H	A	-2.4679
4	K	A	-3.0725
5	S	A	0.0000
6	E	A	-2.1866
7	I	A	0.0000
8	A	A	0.0000
9	H	A	-2.2485
10	R	A	-2.0195
11	F	A	-2.4509
12	K	A	-3.0936
13	D	A	-3.0691
14	L	A	-2.2317
15	G	A	-2.4164
16	E	A	-3.1959
17	E	A	-2.7840
18	H	A	-1.9500
19	F	A	0.0000
20	K	A	-1.8005
21	G	A	0.0000
22	L	A	0.0000
23	V	A	0.0000
24	L	A	0.0000
25	I	A	0.0000
26	A	A	0.0000
27	F	A	0.0000
28	S	A	0.0000
29	Q	A	0.0000
30	Y	A	0.0000
31	L	A	0.0000
32	Q	A	0.0000
33	Q	A	-1.5739
34	C	A	0.0000
35	P	A	-1.1379
36	F	A	-1.3920
37	D	A	-2.3581
38	E	A	-1.9032
39	H	A	0.0000
40	V	A	-1.6118
41	K	A	-2.2322
42	L	A	-1.6890
43	V	A	0.0000
44	N	A	-2.2584
45	E	A	-2.8875
46	L	A	0.0000
47	T	A	0.0000
48	E	A	-2.9747
49	F	A	-1.6286
50	A	A	0.0000
51	K	A	-2.6107
52	T	A	-1.8409
53	C	A	0.0000
54	V	A	-1.3215
55	A	A	-1.3538
56	D	A	-2.7450
57	E	A	-3.0673
58	S	A	-2.2121
59	H	A	-2.1672
60	A	A	-1.3395
61	G	A	-1.2844
62	C	A	0.0000
63	E	A	-3.1731
64	K	A	-1.9356
65	S	A	-1.2756
66	L	A	-0.6671
67	H	A	-0.7282
68	T	A	0.0000
69	L	A	0.0000
70	F	A	-0.1278
71	G	A	0.0000
72	D	A	-0.8568
73	E	A	-1.2469
74	L	A	0.0000
75	C	A	-1.4176
76	K	A	-1.7918
77	V	A	0.0000
78	A	A	-0.9665
79	S	A	-1.4070
80	L	A	0.0000
81	R	A	-3.4386
82	E	A	-2.9955
83	T	A	-1.9653
84	Y	A	-1.8032
85	G	A	-2.5901
86	D	A	-2.9676
87	M	A	0.0000
88	A	A	-2.7489
89	D	A	-3.1833
90	C	A	0.0000
91	C	A	-2.5339
92	E	A	-3.2335
93	K	A	-3.7775
94	Q	A	-3.3133
95	E	A	-3.2033
96	P	A	-2.7904
97	E	A	-3.6203
98	R	A	-3.3616
99	N	A	0.0000
100	E	A	-2.8182
101	C	A	-1.8893
102	F	A	0.0000
103	L	A	-0.8361
104	S	A	-0.8643
105	H	A	-1.0606
106	K	A	0.0000
107	D	A	-1.7890
108	D	A	0.0000
109	S	A	-1.2010
110	P	A	-1.6460
111	D	A	-2.3584
112	L	A	-1.3437
113	P	A	-1.2678
114	K	A	-1.7105
115	L	A	-0.3528
116	K	A	-1.8266
117	P	A	-1.3846
118	D	A	-2.1391
119	P	A	-2.1452
120	N	A	-2.4649
121	T	A	-1.9513
122	L	A	-1.9820
123	C	A	0.0000
124	D	A	-3.4195
125	E	A	-3.4263
126	F	A	-3.3900
127	K	A	-3.5859
128	A	A	-2.8180
129	D	A	-3.7366
130	E	A	-4.2881
131	K	A	-4.0152
132	K	A	-3.3843
133	F	A	0.0000
134	W	A	0.0000
135	G	A	-1.7022
136	K	A	-1.7513
137	Y	A	-0.7335
138	L	A	0.0000
139	Y	A	0.0000
140	E	A	0.0000
141	I	A	0.0106
142	A	A	0.0000
143	R	A	-0.6460
144	R	A	-1.0222
145	H	A	-0.3127
146	P	A	0.0000
147	Y	A	-0.1737
148	F	A	0.0000
149	Y	A	0.0000
150	A	A	0.0000
151	P	A	0.0000
152	E	A	0.0000
153	L	A	0.0000
154	L	A	0.0000
155	Y	A	0.0000
156	Y	A	0.0000
157	A	A	0.0000
158	N	A	-1.8709
159	K	A	-2.0161
160	Y	A	0.0000
161	N	A	-2.0612
162	G	A	-1.8590
163	V	A	0.0000
164	F	A	0.0000
165	Q	A	-2.8976
166	E	A	-2.7643
167	C	A	0.0000
168	C	A	0.0000
169	Q	A	-2.5869
170	A	A	-2.4094
171	E	A	-3.0259
172	D	A	-2.9637
173	K	A	-2.4042
174	G	A	-1.4727
175	A	A	-0.9276
176	C	A	-1.2267
177	L	A	0.0000
178	L	A	-0.8465
179	P	A	-1.2138
180	K	A	-1.6071
181	I	A	0.0000
182	E	A	-2.9802
183	T	A	-2.4004
184	M	A	0.0000
185	R	A	-2.5301
186	E	A	-2.9822
187	K	A	-2.6253
188	V	A	0.0000
189	L	A	-0.0307
190	T	A	-0.6522
191	S	A	-0.6231
192	S	A	0.0000
193	A	A	-0.2141
194	R	A	-0.5041
195	Q	A	0.0000
196	R	A	-0.4350
197	L	A	-0.3102
198	R	A	-0.7007
199	C	A	0.0000
200	A	A	-0.7957
201	S	A	0.0000
202	I	A	-1.8561
203	Q	A	-2.0550
204	K	A	-1.9154
205	F	A	-1.4557
206	G	A	-1.9214
207	E	A	-2.9164
208	R	A	-2.9648
209	A	A	-1.7081
210	L	A	0.0000
211	K	A	-2.3512
212	A	A	-1.3934
213	W	A	-0.7166
214	S	A	0.0000
215	V	A	0.0000
216	A	A	0.0000
217	R	A	-0.7258
218	L	A	0.0000
219	S	A	0.0000
220	Q	A	0.0000
221	K	A	0.0000
222	F	A	0.0000
223	P	A	0.0000
224	K	A	-1.5512
225	A	A	0.0000
226	E	A	-1.3465
227	F	A	0.0347
228	V	A	1.0248
229	E	A	-0.3553
230	V	A	0.0000
231	T	A	-0.4595
232	K	A	-1.1349
233	L	A	0.0000
234	V	A	0.0000
235	T	A	-1.5087
236	D	A	-2.2809
237	L	A	-1.3672
238	T	A	0.0000
239	K	A	-2.3518
240	V	A	0.0000
241	H	A	0.0000
242	K	A	-1.9032
243	E	A	-1.5189
244	C	A	0.0000
245	C	A	0.0000
246	H	A	-1.2148
247	G	A	-0.7823
248	D	A	-0.7327
249	L	A	0.0000
250	L	A	0.0000
251	E	A	-1.2914
252	C	A	0.0000
253	A	A	0.0000
254	D	A	-1.7625
255	D	A	-2.4265
256	R	A	0.0000
257	A	A	-1.6970
258	D	A	-2.8751
259	L	A	0.0000
260	A	A	0.0000
261	K	A	-2.6825
262	Y	A	-1.7141
263	I	A	0.0000
264	C	A	-2.4569
265	D	A	-2.6086
266	N	A	-2.1249
267	Q	A	-2.3263
268	D	A	-2.7754
269	T	A	-1.8997
270	I	A	0.0000
271	S	A	0.0000
272	S	A	-2.1618
273	K	A	-2.6844
274	L	A	0.0000
275	K	A	-3.5587
276	E	A	-3.4913
277	C	A	0.0000
278	C	A	-2.8551
279	D	A	-3.0913
280	K	A	-2.2929
281	P	A	-0.7747
282	L	A	-0.0392
283	L	A	-0.0757
284	E	A	-1.0323
285	K	A	-1.5162
286	S	A	0.0000
287	H	A	-0.7050
288	C	A	-1.4486
289	I	A	0.0000
290	A	A	-1.2153
291	E	A	-2.3810
292	V	A	0.0000
293	E	A	-3.1239
294	K	A	-2.6576
295	D	A	0.0000
296	A	A	-0.6274
297	I	A	-0.3359
298	P	A	-1.1115
299	E	A	-2.1727
300	N	A	-2.0057
301	L	A	-0.9667
302	P	A	-0.9663
303	P	A	-0.7002
304	L	A	-0.6564
305	T	A	-1.0763
306	A	A	-1.5971
307	D	A	-2.8664
308	F	A	0.0000
309	A	A	0.0000
310	E	A	-3.1585
311	D	A	-3.4341
312	K	A	-3.4100
313	D	A	-2.9887
314	V	A	0.0000
315	C	A	-2.4290
316	K	A	-3.4820
317	N	A	-3.2666
318	Y	A	0.0000
319	Q	A	-3.5536
320	E	A	-3.5050
321	A	A	-2.5999
322	K	A	-3.3215
323	D	A	-2.9663
324	A	A	-1.5039
325	F	A	-1.3602
326	L	A	-1.1255
327	G	A	-0.8747
328	S	A	-0.2918
329	F	A	0.0000
330	L	A	0.0000
331	Y	A	0.0000
332	E	A	-0.7197
333	Y	A	0.0000
334	S	A	0.0000
335	R	A	-0.8850
336	R	A	-0.4745
337	H	A	-0.8177
338	P	A	-1.2666
339	E	A	-2.1611
340	Y	A	-1.0012
341	A	A	0.0000
342	V	A	-0.1065
343	S	A	0.1085
344	V	A	0.0000
345	L	A	0.0000
346	L	A	-0.1010
347	R	A	0.0000
348	L	A	0.0000
349	A	A	-0.8556
350	K	A	-1.5779
351	E	A	-1.4834
352	Y	A	0.0000
353	E	A	-2.4909
354	A	A	-1.9620
355	T	A	0.0000
356	L	A	0.0000
357	E	A	-3.2919
358	E	A	-3.0932
359	C	A	0.0000
360	C	A	-2.3813
361	A	A	-2.3475
362	K	A	-3.6218
363	D	A	-3.4478
364	D	A	-3.1784
365	P	A	-2.5290
366	H	A	-2.0529
367	A	A	-1.1732
368	C	A	-1.0286
369	Y	A	0.0000
370	S	A	-1.0885
371	T	A	-0.9288
372	V	A	0.0000
373	F	A	-1.5422
374	D	A	-2.9786
375	K	A	-2.6435
376	L	A	0.0000
377	K	A	-3.1098
378	H	A	-3.1434
379	L	A	-2.1525
380	V	A	-1.8656
381	D	A	-3.3286
382	E	A	-3.2344
383	P	A	0.0000
384	Q	A	-2.6445
385	N	A	-2.8539
386	L	A	-1.7949
387	I	A	0.0000
388	K	A	-3.5220
389	Q	A	-3.0445
390	N	A	-2.5118
391	C	A	0.0000
392	D	A	-3.8675
393	Q	A	-2.8622
394	F	A	0.0000
395	E	A	-3.3816
396	K	A	-3.0305
397	L	A	-1.1156
398	G	A	-1.3982
399	E	A	-1.3826
400	Y	A	0.0682
401	G	A	-0.3105
402	F	A	0.0000
403	Q	A	0.0000
404	N	A	-0.1988
405	A	A	-0.4355
406	L	A	0.0000
407	I	A	0.0000
408	V	A	-0.6201
409	R	A	-1.0705
410	Y	A	0.0000
411	T	A	0.0000
412	R	A	-1.3854
413	K	A	-0.8758
414	V	A	0.0000
415	P	A	0.0000
416	Q	A	-1.2518
417	V	A	0.0000
418	S	A	-0.4175
419	T	A	0.0000
420	P	A	-0.6857
421	T	A	0.0000
422	L	A	0.0000
423	V	A	0.0000
424	E	A	-1.9989
425	V	A	0.0000
426	S	A	0.0000
427	R	A	-1.1270
428	S	A	-0.9566
429	L	A	0.0000
430	G	A	0.0000
431	K	A	-1.1772
432	V	A	0.0000
433	G	A	0.0000
434	T	A	-1.1012
435	R	A	-0.8420
436	C	A	0.0000
437	C	A	0.0000
438	T	A	-1.2611
439	K	A	-1.8239
440	P	A	-2.1156
441	E	A	-3.0448
442	S	A	-2.4257
443	E	A	-2.9844
444	R	A	-2.3333
445	M	A	0.0000
446	P	A	-1.0317
447	C	A	-0.7224
448	T	A	0.0000
449	E	A	0.0000
450	D	A	-0.2797
451	Y	A	-0.0965
452	L	A	0.0993
453	S	A	-0.0631
454	L	A	0.0000
455	I	A	-0.2851
456	L	A	0.0000
457	N	A	0.0000
458	R	A	-1.0563
459	L	A	0.0000
460	C	A	0.0000
461	V	A	0.0000
462	L	A	-1.0067
463	H	A	0.0000
464	E	A	-2.0288
465	K	A	-1.9647
466	T	A	-0.9926
467	P	A	-1.1743
468	V	A	-0.5760
469	S	A	0.0000
470	E	A	-2.2189
471	K	A	-1.4853
472	V	A	0.0000
473	T	A	-1.7454
474	K	A	-2.0637
475	C	A	0.0000
476	C	A	0.0000
477	T	A	-1.5606
478	E	A	-2.0643
479	S	A	-1.1405
480	L	A	-0.2174
481	V	A	-0.0794
482	N	A	-0.4515
483	R	A	0.0000
484	R	A	0.0000
485	P	A	-0.1990
486	C	A	-0.2723
487	F	A	0.0000
488	S	A	0.0170
489	A	A	0.0910
490	L	A	-0.0658
491	T	A	-0.6836
492	P	A	-1.3642
493	D	A	-1.3432
494	E	A	-2.0105
495	T	A	-0.6663
496	Y	A	-0.1651
497	V	A	0.9453
498	P	A	-0.4573
499	K	A	-1.2280
500	A	A	-0.6215
501	F	A	-0.9156
502	D	A	-2.0763
503	E	A	-2.7159
504	K	A	-2.5167
505	L	A	-1.1228
506	F	A	-0.7481
507	T	A	-1.0141
508	F	A	-1.0714
509	H	A	-1.9197
510	A	A	-2.0099
511	D	A	-2.2911
512	I	A	0.0000
513	C	A	-1.0719
514	T	A	-1.0247
515	L	A	-1.1260
516	P	A	-1.4293
517	D	A	-2.2572
518	T	A	-1.4399
519	E	A	-1.6090
520	K	A	-1.9603
521	Q	A	-1.2335
522	I	A	-1.0949
523	K	A	-1.2948
524	K	A	-0.6962
525	Q	A	0.0000
526	T	A	-0.5112
527	A	A	-0.1519
528	L	A	0.0000
529	V	A	0.0000
530	E	A	-0.4435
531	L	A	-0.1930
532	L	A	0.0000
533	K	A	0.0000
534	H	A	-0.8589
535	K	A	-1.1691
536	P	A	-1.3688
537	K	A	-2.3375
538	A	A	0.0000
539	T	A	-2.3795
540	E	A	-3.4973
541	E	A	-3.5160
542	Q	A	-2.4123
543	L	A	0.0000
544	K	A	-3.4827
545	T	A	-2.4385
546	V	A	0.0000
547	M	A	-1.1243
548	E	A	-2.0510
549	N	A	-1.4467
550	F	A	-0.6699
551	V	A	-0.2031
552	A	A	-1.0710
553	F	A	0.0000
554	V	A	-0.9633
555	D	A	-2.0215
556	K	A	-2.3539
557	C	A	0.0000
558	C	A	-1.8470
559	A	A	-1.4494
560	A	A	-2.1509
561	D	A	-2.7451
562	D	A	-2.9692
563	K	A	-2.8198
564	E	A	-2.7513
565	A	A	-1.3690
566	C	A	0.0000
567	F	A	0.0000
568	A	A	-0.1929
569	V	A	0.7740
570	E	A	-0.5509
571	G	A	-0.0974
572	P	A	-0.3813
573	K	A	-0.9305
574	L	A	-0.1693
575	V	A	0.2454
576	V	A	1.0831
577	S	A	0.0779
578	T	A	-0.0322
579	Q	A	0.1000
580	T	A	0.1478
581	A	A	-0.0232
582	L	A	0.0000
583	A	A	-0.2297