Project name: gqs-p912

Chain sequence(s)	H: VTLKESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGAGIDAFDIWGQGTMVTVS; L: ALTQPASVSGSPGQSITISCTGTSSDVGAYNYVTWYQQYPGKAPKLMIYDVSERPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCSSFTSSISWVFGGGTKLTVL
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.6898
• Maximal score value: 1.632
• Average score: -0.5633
• Total score value: -126.1822

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
3	A	L	0.0540
4	L	L	0.0000
5	T	L	-0.1298
6	Q	L	0.0000
7	P	L	-0.3937
8	A	L	-0.6249
10	S	L	-0.9334
11	V	L	-0.4684
12	S	L	-0.0962
13	G	L	0.0000
14	S	L	-0.1896
15	P	L	-0.8090
16	G	L	-1.4780
17	Q	L	-1.7121
18	S	L	-1.0327
19	I	L	-0.1104
20	T	L	0.0167
21	I	L	0.0000
22	S	L	-0.1630
23	C	L	0.0000
24	T	L	-0.3155
25	G	L	-0.6158
26	T	L	-0.9490
27	S	L	-0.9663
28	S	L	-1.2167
29	D	L	-1.7523
30	V	L	-0.6915
30A	G	L	-0.8223
30B	A	L	-0.2092
30C	Y	L	0.5099
31	N	L	-0.4769
32	Y	L	0.3852
33	V	L	0.0000
34	T	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	0.0000
39	Y	L	-1.2668
40	P	L	-1.1242
41	G	L	-1.4781
42	K	L	-2.3299
43	A	L	-1.4793
44	P	L	0.0000
45	K	L	-1.5368
46	L	L	0.0000
47	M	L	0.0000
48	I	L	0.0000
49	Y	L	-0.6918
50	D	L	-0.7150
51	V	L	-0.6835
52	S	L	-1.2341
53	E	L	-2.0383
54	R	L	-2.0303
55	P	L	-1.3867
56	S	L	-1.0740
57	G	L	-0.8274
58	V	L	-0.9290
59	S	L	-1.0818
60	N	L	-1.7625
61	R	L	-1.2494
62	F	L	0.0000
63	S	L	-0.9522
64	G	L	0.0000
65	S	L	-0.6426
66	K	L	-0.6506
67	S	L	-0.7125
68	G	L	-0.8930
69	N	L	-1.1124
70	T	L	-0.7716
71	A	L	0.0000
72	S	L	-0.2076
73	L	L	0.0000
74	T	L	-0.1780
75	I	L	0.0000
76	S	L	-1.0951
77	G	L	-1.1331
78	L	L	0.0000
79	Q	L	-1.7291
80	A	L	-1.2652
81	E	L	-2.2642
82	D	L	0.0000
83	E	L	-1.8620
84	A	L	0.0000
85	D	L	-1.9157
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	S	L	0.0000
90	S	L	0.0000
91	F	L	0.7286
92	T	L	0.4746
93	S	L	0.3577
94	S	L	0.4076
95	I	L	1.0623
95A	S	L	0.0000
96	W	L	0.5665
97	V	L	0.2235
98	F	L	0.0239
99	G	L	-0.7184
100	G	L	-1.2147
101	G	L	-1.1470
102	T	L	0.0000
103	K	L	-2.2981
104	L	L	0.0000
105	T	L	-0.6331
106	V	L	0.0592
107	L	L	1.3490
2	V	H	1.6320
3	T	H	0.1861
4	L	H	0.0000
5	K	H	-2.1859
6	E	H	-1.4808
7	S	H	-1.2116
8	G	H	-0.7367
9	G	H	-0.2135
10	G	H	0.2767
11	L	H	1.1552
12	V	H	0.0000
13	Q	H	-1.2760
14	P	H	-1.3467
15	G	H	-1.2507
16	G	H	-1.1229
17	S	H	-1.4109
18	L	H	-1.0612
19	R	H	-2.1184
20	L	H	0.0000
21	S	H	-1.0110
22	C	H	0.0000
23	A	H	-1.2475
24	A	H	0.0000
25	S	H	-0.2665
26	G	H	0.3772
27	F	H	0.4322
28	T	H	-0.3278
29	F	H	0.0000
30	S	H	-0.9082
31	S	H	-0.4261
32	Y	H	0.0168
33	A	H	0.0023
34	M	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.8494
40	A	H	-1.1625
41	P	H	-0.9221
42	G	H	-1.4626
43	K	H	-2.2851
44	G	H	-1.5148
45	L	H	0.0000
46	E	H	-0.9891
47	W	H	0.1092
48	V	H	0.0000
49	S	H	0.0000
50	A	H	0.5540
51	I	H	0.0000
52	S	H	-0.4029
52A	G	H	-0.6724
53	S	H	-0.8167
54	G	H	-0.6938
55	G	H	-0.6592
56	S	H	-0.2575
57	T	H	0.1370
58	Y	H	0.7185
59	Y	H	0.5955
60	A	H	-0.7170
61	D	H	-2.3095
62	S	H	-1.6763
63	V	H	0.0000
64	K	H	-2.4189
65	G	H	-2.0978
66	R	H	-2.3344
67	F	H	-1.3076
68	T	H	-0.8141
69	I	H	0.0000
70	S	H	-0.3835
71	R	H	-1.3164
72	D	H	-2.3181
73	N	H	-2.6005
74	S	H	-2.0632
75	K	H	-2.6898
76	N	H	-2.1558
77	T	H	0.0000
78	L	H	0.0000
79	Y	H	-0.6327
80	L	H	0.0000
81	Q	H	-1.3676
82	M	H	0.0000
82A	N	H	-1.7051
82B	S	H	-1.3126
82C	L	H	0.0000
83	R	H	-1.6498
84	A	H	-1.3781
85	E	H	-1.9680
86	D	H	0.0000
87	T	H	-0.4236
88	A	H	0.0000
89	V	H	0.3526
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	R	H	-0.2368
95	G	H	0.0000
96	A	H	-0.0432
97	G	H	0.2672
98	I	H	1.3956
99	D	H	-0.1567
100	A	H	0.0000
100A	F	H	0.0000
101	D	H	-1.2703
102	I	H	-0.2305
103	W	H	-0.7940
104	G	H	0.0000
105	Q	H	-2.0553
106	G	H	-1.1807
107	T	H	-0.3808
108	M	H	0.6458
109	V	H	0.0000
110	T	H	0.1661
111	V	H	0.0000
112	S	H	-0.6699