| Chain sequence(s) |
B: SSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEALNLAQRPRDLISNINVIVLELKGETTFMCEYADETATIVEFLNRWITFCQSIISTL D: SSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEALNLAQRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTL |
| Distance of aggregation | 5 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 4 | S | B | -0.2384 | |
| 5 | S | B | -0.2178 | |
| 6 | S | B | -0.2465 | |
| 7 | T | B | -0.2386 | |
| 8 | K | B | -1.1157 | |
| 9 | K | B | -1.4420 | |
| 10 | T | B | -0.2848 | |
| 11 | Q | B | -0.2768 | |
| 12 | L | B | 0.0000 | |
| 13 | Q | B | -0.2328 | |
| 14 | L | B | 0.0000 | |
| 15 | E | B | -0.3550 | |
| 16 | H | B | -0.2038 | |
| 17 | L | B | 0.0000 | |
| 18 | L | B | 0.1622 | |
| 19 | L | B | 0.0000 | |
| 20 | D | B | -0.1770 | |
| 21 | L | B | 0.0000 | |
| 22 | Q | B | -0.2098 | |
| 23 | M | B | 0.1727 | |
| 24 | I | B | 0.0000 | |
| 25 | L | B | 0.1506 | |
| 26 | N | B | -0.1927 | |
| 27 | G | B | -0.2478 | |
| 28 | I | B | 0.0000 | |
| 29 | N | B | -1.5060 | |
| 30 | N | B | -1.4571 | |
| 31 | Y | B | -0.2751 | |
| 32 | K | B | -1.8824 | |
| 33 | N | B | -1.6280 | |
| 34 | P | B | -0.5871 | |
| 35 | K | B | -0.5555 | |
| 36 | L | B | 0.2439 | |
| 37 | T | B | -0.3421 | |
| 38 | R | B | -1.8570 | |
| 39 | M | B | 0.0000 | |
| 40 | L | B | 0.8700 | |
| 41 | T | B | 0.1492 | |
| 42 | F | B | -0.0384 | |
| 43 | K | B | -1.6471 | |
| 44 | F | B | 0.0000 | |
| 45 | Y | B | 0.8760 | |
| 46 | M | B | 0.0000 | |
| 47 | P | B | 0.0000 | |
| 48 | K | B | -1.9422 | |
| 49 | K | B | -1.9982 | |
| 50 | A | B | -0.3134 | |
| 51 | T | B | -0.3449 | |
| 52 | E | B | -1.4778 | |
| 53 | L | B | -0.1548 | |
| 54 | K | B | -0.8709 | |
| 55 | H | B | -0.2605 | |
| 56 | L | B | 0.0000 | |
| 57 | Q | B | -0.2211 | |
| 58 | C | B | 0.0000 | |
| 59 | L | B | 0.0000 | |
| 60 | E | B | -0.7223 | |
| 61 | E | B | -1.9195 | |
| 62 | E | B | -0.5074 | |
| 63 | L | B | 0.0000 | |
| 64 | K | B | -1.7064 | |
| 65 | P | B | -0.3418 | |
| 66 | L | B | 0.0000 | |
| 67 | E | B | -0.6157 | |
| 68 | E | B | -1.6408 | |
| 69 | A | B | 0.0000 | |
| 70 | L | B | 0.0718 | |
| 71 | N | B | -0.1153 | |
| 72 | L | B | 1.4707 | |
| 73 | A | B | 0.0853 | |
| 74 | Q | B | -1.1972 | |
| 81 | R | B | -1.8441 | |
| 82 | P | B | 0.0000 | |
| 83 | R | B | -2.1001 | |
| 84 | D | B | -1.6887 | |
| 85 | L | B | 0.1334 | |
| 86 | I | B | 0.0000 | |
| 87 | S | B | -0.4361 | |
| 88 | N | B | -0.5333 | |
| 89 | I | B | 0.0000 | |
| 90 | N | B | -0.0476 | |
| 91 | V | B | 1.6589 | |
| 92 | I | B | 0.5161 | |
| 93 | V | B | 0.0000 | |
| 94 | L | B | 0.5674 | |
| 95 | E | B | -1.6552 | |
| 96 | L | B | 0.0000 | |
| 97 | K | B | -0.3140 | |
| 98 | G | B | -0.2972 | |
| 100 | E | B | -1.8243 | |
| 101 | T | B | -0.3697 | |
| 102 | T | B | -0.0143 | |
| 103 | F | B | 0.5128 | |
| 104 | M | B | 1.1415 | |
| 105 | C | B | 0.0047 | |
| 106 | E | B | -1.7427 | |
| 107 | Y | B | -0.0587 | |
| 108 | A | B | -0.4299 | |
| 109 | D | B | -2.1193 | |
| 110 | E | B | -2.1529 | |
| 111 | T | B | -0.3646 | |
| 112 | A | B | 0.0000 | |
| 113 | T | B | -0.0151 | |
| 114 | I | B | 0.0000 | |
| 115 | V | B | 0.1517 | |
| 116 | E | B | -1.6953 | |
| 117 | F | B | 0.0000 | |
| 118 | L | B | 0.0000 | |
| 119 | N | B | -1.0033 | |
| 120 | R | B | -1.1424 | |
| 121 | W | B | 0.0000 | |
| 122 | I | B | 0.1883 | |
| 123 | T | B | -0.0342 | |
| 124 | F | B | 0.0000 | |
| 125 | C | B | 0.0000 | |
| 126 | Q | B | -1.2183 | |
| 127 | S | B | -0.2925 | |
| 128 | I | B | 0.2488 | |
| 129 | I | B | 0.3753 | |
| 130 | S | B | -0.1566 | |
| 131 | T | B | 0.1331 | |
| 132 | L | B | 1.3248 | |
| 4 | S | D | -0.2517 | |
| 5 | S | D | -0.2906 | |
| 6 | S | D | -0.2581 | |
| 7 | T | D | -0.2638 | |
| 8 | K | D | -1.2261 | |
| 9 | K | D | -0.9874 | |
| 10 | T | D | -0.2302 | |
| 11 | Q | D | -0.4143 | |
| 12 | L | D | 0.0000 | |
| 13 | Q | D | -0.1704 | |
| 14 | L | D | 0.0000 | |
| 15 | E | D | -0.7285 | |
| 16 | H | D | -0.2572 | |
| 17 | L | D | 0.0000 | |
| 18 | L | D | 0.0000 | |
| 19 | L | D | 0.0000 | |
| 20 | D | D | -0.1446 | |
| 21 | L | D | 0.0000 | |
| 22 | Q | D | -0.1790 | |
| 23 | M | D | 0.2564 | |
| 24 | I | D | 0.0000 | |
| 25 | L | D | 0.1567 | |
| 26 | N | D | -0.3150 | |
| 27 | G | D | -0.2975 | |
| 28 | I | D | 0.0000 | |
| 29 | N | D | -1.4783 | |
| 30 | N | D | -1.3165 | |
| 31 | Y | D | -0.2982 | |
| 32 | K | D | -1.8917 | |
| 33 | N | D | -1.6121 | |
| 34 | P | D | -0.5239 | |
| 35 | K | D | -0.6832 | |
| 36 | L | D | 0.2146 | |
| 37 | T | D | -0.3425 | |
| 38 | R | D | -1.8570 | |
| 39 | M | D | 0.0000 | |
| 40 | L | D | 0.6666 | |
| 41 | T | D | 0.1124 | |
| 42 | F | D | 0.0032 | |
| 43 | K | D | -1.6396 | |
| 44 | F | D | 0.0000 | |
| 45 | Y | D | 0.8898 | |
| 46 | M | D | 0.0000 | |
| 47 | P | D | 0.0000 | |
| 48 | K | D | -1.8778 | |
| 49 | K | D | -1.5215 | |
| 50 | A | D | -0.2216 | |
| 51 | T | D | -0.3848 | |
| 52 | E | D | -1.6906 | |
| 53 | L | D | -0.2276 | |
| 54 | K | D | -0.9836 | |
| 55 | H | D | -0.2850 | |
| 56 | L | D | 0.0000 | |
| 57 | Q | D | 0.0000 | |
| 58 | C | D | 0.0000 | |
| 59 | L | D | 0.0000 | |
| 60 | E | D | -0.5955 | |
| 61 | E | D | -1.5058 | |
| 62 | E | D | -0.4452 | |
| 63 | L | D | 0.0000 | |
| 64 | K | D | -1.7398 | |
| 65 | P | D | -0.5560 | |
| 66 | L | D | 0.0000 | |
| 67 | E | D | -0.8194 | |
| 68 | E | D | -1.8822 | |
| 69 | A | D | 0.0000 | |
| 70 | L | D | 0.1224 | |
| 71 | N | D | -0.0445 | |
| 72 | L | D | 1.4832 | |
| 73 | A | D | 0.0705 | |
| 74 | Q | D | -1.1972 | |
| 81 | R | D | -1.8502 | |
| 82 | P | D | -0.7017 | |
| 83 | R | D | -2.1771 | |
| 84 | D | D | -2.0559 | |
| 85 | L | D | 0.1404 | |
| 86 | I | D | 0.0000 | |
| 87 | S | D | -0.4832 | |
| 88 | N | D | -0.6522 | |
| 89 | I | D | 0.0000 | |
| 90 | N | D | -0.0714 | |
| 91 | V | D | 1.7426 | |
| 92 | I | D | 0.5409 | |
| 93 | V | D | 0.0000 | |
| 94 | L | D | -0.0114 | |
| 95 | E | D | -1.7571 | |
| 96 | L | D | 0.0000 | |
| 97 | K | D | 0.0000 | |
| 98 | G | D | -0.2253 | |
| 99 | S | D | -0.5274 | |
| 100 | E | D | -1.8664 | |
| 101 | T | D | -0.3986 | |
| 102 | T | D | -0.0144 | |
| 103 | F | D | 0.5472 | |
| 104 | M | D | 1.1537 | |
| 105 | C | D | 0.1170 | |
| 106 | E | D | -1.2843 | |
| 107 | Y | D | -0.0584 | |
| 108 | A | D | -0.4471 | |
| 109 | D | D | -2.1189 | |
| 110 | E | D | -2.1524 | |
| 111 | T | D | -0.3656 | |
| 112 | A | D | -0.0025 | |
| 113 | T | D | -0.0143 | |
| 114 | I | D | 0.0000 | |
| 115 | V | D | 0.1833 | |
| 116 | E | D | -1.4855 | |
| 117 | F | D | 0.0000 | |
| 118 | L | D | 0.0000 | |
| 119 | N | D | -1.1589 | |
| 120 | R | D | -0.8366 | |
| 121 | W | D | 0.0000 | |
| 122 | I | D | 0.1852 | |
| 123 | T | D | -0.0348 | |
| 124 | F | D | 0.0000 | |
| 125 | C | D | 0.0000 | |
| 126 | Q | D | -0.9166 | |
| 127 | S | D | -0.2813 | |
| 128 | I | D | 0.0000 | |
| 129 | I | D | 0.2665 | |
| 130 | S | D | -0.1702 | |
| 131 | T | D | 0.0518 | |
| 132 | L | D | 0.8734 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine