Project name: 4lly:A
Status: done
submitted: 2019-03-21 14:56:33, status changed: 2019-03-21 15:07:27
Settings
Chain sequence(s)
|
A: EVQLVESGGGLVQPGGSLRLSCAASGFTFTDYTMDWVRKAPGKGLEWVADVNPNSGGSIYNQEFKGRFTLSVDRSKNTLYLQMNSLRAEDTAVYYCARNLGPSFYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVATGPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.0416
-
Maximal score value
-
2.3558
-
Average score
-
-0.5807
-
Total score value
-
-127.7458
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
E |
A |
-2.1293 |
|
2 |
V |
A |
-1.4537 |
|
3 |
Q |
A |
-1.5250 |
|
4 |
L |
A |
0.0000 |
|
5 |
V |
A |
0.1032 |
|
6 |
E |
A |
0.0000 |
|
7 |
S |
A |
-0.6183 |
|
8 |
G |
A |
-1.0622 |
|
9 |
G |
A |
-0.7653 |
|
10 |
G |
A |
0.0000 |
|
11 |
L |
A |
-0.3453 |
|
12 |
V |
A |
0.0000 |
|
13 |
Q |
A |
-1.7479 |
|
14 |
P |
A |
-1.8988 |
|
15 |
G |
A |
-1.5374 |
|
16 |
G |
A |
-1.1919 |
|
17 |
S |
A |
-1.2907 |
|
18 |
L |
A |
-1.1163 |
|
19 |
R |
A |
-2.0168 |
|
20 |
L |
A |
0.0000 |
|
21 |
S |
A |
-0.4102 |
|
22 |
C |
A |
0.0000 |
|
23 |
A |
A |
-0.5123 |
|
24 |
A |
A |
0.0000 |
|
25 |
S |
A |
-1.1901 |
|
26 |
G |
A |
-1.1816 |
|
27 |
F |
A |
-0.6990 |
|
28 |
T |
A |
-0.6277 |
|
29 |
F |
A |
0.0000 |
|
30 |
T |
A |
-1.6295 |
|
31 |
D |
A |
-1.6700 |
|
32 |
Y |
A |
-0.4204 |
|
33 |
T |
A |
-0.1567 |
|
34 |
M |
A |
0.0000 |
|
35 |
D |
A |
0.0000 |
|
36 |
W |
A |
0.0000 |
|
37 |
V |
A |
0.0000 |
|
38 |
R |
A |
-0.4814 |
|
39 |
K |
A |
-0.9596 |
|
40 |
A |
A |
0.0000 |
|
41 |
P |
A |
-1.2908 |
|
42 |
G |
A |
-1.4811 |
|
43 |
K |
A |
-2.2468 |
|
44 |
G |
A |
-1.2052 |
|
45 |
L |
A |
0.0941 |
|
46 |
E |
A |
-0.8499 |
|
47 |
W |
A |
0.0334 |
|
48 |
V |
A |
0.0000 |
|
49 |
A |
A |
0.0000 |
|
50 |
D |
A |
0.0000 |
|
51 |
V |
A |
0.0000 |
|
52 |
N |
A |
-1.2029 |
|
53 |
P |
A |
0.0000 |
|
54 |
N |
A |
-1.9559 |
|
55 |
S |
A |
-1.1051 |
|
56 |
G |
A |
-1.2569 |
|
57 |
G |
A |
-0.5138 |
|
58 |
S |
A |
0.5055 |
|
59 |
I |
A |
1.4574 |
|
60 |
Y |
A |
-0.1645 |
|
61 |
N |
A |
-1.3476 |
|
62 |
Q |
A |
-2.5217 |
|
63 |
E |
A |
-3.0416 |
|
64 |
F |
A |
0.0000 |
|
65 |
K |
A |
-2.6120 |
|
66 |
G |
A |
-1.8680 |
|
67 |
R |
A |
-1.6974 |
|
68 |
F |
A |
0.0000 |
|
69 |
T |
A |
-0.5585 |
|
70 |
L |
A |
0.0000 |
|
71 |
S |
A |
-0.4220 |
|
72 |
V |
A |
-1.1150 |
|
73 |
D |
A |
-1.9918 |
|
74 |
R |
A |
-3.0390 |
|
75 |
S |
A |
-2.2243 |
|
76 |
K |
A |
-2.7752 |
|
77 |
N |
A |
-2.2315 |
|
78 |
T |
A |
0.0000 |
|
79 |
L |
A |
0.0000 |
|
80 |
Y |
A |
-0.3536 |
|
81 |
L |
A |
0.0000 |
|
82 |
Q |
A |
-1.0675 |
|
83 |
M |
A |
0.0000 |
|
84 |
N |
A |
-1.3377 |
|
85 |
S |
A |
-1.2628 |
|
86 |
L |
A |
0.0000 |
|
87 |
R |
A |
-2.7552 |
|
88 |
A |
A |
-1.9541 |
|
89 |
E |
A |
-2.4126 |
|
90 |
D |
A |
0.0000 |
|
91 |
T |
A |
-0.8942 |
|
92 |
A |
A |
0.0000 |
|
93 |
V |
A |
0.1906 |
|
94 |
Y |
A |
0.0000 |
|
95 |
Y |
A |
0.0618 |
|
96 |
C |
A |
0.0000 |
|
97 |
A |
A |
0.0000 |
|
98 |
R |
A |
0.0000 |
|
99 |
N |
A |
0.0000 |
|
100 |
L |
A |
1.3136 |
|
101 |
G |
A |
0.3812 |
|
102 |
P |
A |
0.3296 |
|
103 |
S |
A |
0.9218 |
|
104 |
F |
A |
1.6484 |
|
105 |
Y |
A |
1.6671 |
|
106 |
F |
A |
0.6277 |
|
107 |
D |
A |
-0.7850 |
|
108 |
Y |
A |
-0.3710 |
|
109 |
W |
A |
-0.0431 |
|
110 |
G |
A |
-0.2949 |
|
111 |
Q |
A |
-1.0067 |
|
112 |
G |
A |
-0.3976 |
|
113 |
T |
A |
-0.1429 |
|
114 |
L |
A |
0.1028 |
|
115 |
V |
A |
0.0000 |
|
116 |
T |
A |
-0.5588 |
|
117 |
V |
A |
0.0000 |
|
118 |
S |
A |
-1.0600 |
|
119 |
S |
A |
-0.7153 |
|
120 |
A |
A |
-0.4985 |
|
121 |
S |
A |
-0.6832 |
|
122 |
T |
A |
-0.8693 |
|
123 |
K |
A |
-1.5325 |
|
124 |
G |
A |
-1.6329 |
|
125 |
P |
A |
-0.6555 |
|
126 |
S |
A |
-0.1373 |
|
127 |
V |
A |
0.0000 |
|
128 |
F |
A |
1.2869 |
|
129 |
P |
A |
0.2723 |
|
130 |
L |
A |
0.5371 |
|
131 |
A |
A |
-0.9851 |
|
132 |
P |
A |
0.0000 |
|
133 |
S |
A |
-1.4545 |
|
134 |
S |
A |
-1.4462 |
|
135 |
K |
A |
-2.0708 |
|
136 |
S |
A |
-1.0527 |
|
137 |
T |
A |
-1.0604 |
|
138 |
S |
A |
-0.9706 |
|
139 |
G |
A |
-0.8378 |
|
140 |
G |
A |
-0.9204 |
|
141 |
T |
A |
-0.6666 |
|
142 |
A |
A |
0.0000 |
|
143 |
A |
A |
-0.1685 |
|
144 |
L |
A |
0.0000 |
|
145 |
G |
A |
0.0000 |
|
146 |
C |
A |
0.0000 |
|
147 |
L |
A |
0.9765 |
|
148 |
V |
A |
0.0000 |
|
149 |
K |
A |
-0.0540 |
|
150 |
D |
A |
-0.4995 |
|
151 |
Y |
A |
0.0000 |
|
152 |
F |
A |
-0.4074 |
|
153 |
P |
A |
0.0000 |
|
154 |
E |
A |
-0.5125 |
|
155 |
P |
A |
-0.7569 |
|
156 |
V |
A |
-0.6990 |
|
157 |
T |
A |
-0.5786 |
|
158 |
V |
A |
-0.3057 |
|
159 |
S |
A |
-0.3225 |
|
160 |
W |
A |
0.0000 |
|
161 |
N |
A |
-0.7658 |
|
162 |
S |
A |
-0.5814 |
|
163 |
G |
A |
-0.5029 |
|
164 |
A |
A |
-0.1945 |
|
165 |
L |
A |
0.0198 |
|
166 |
T |
A |
-0.1549 |
|
167 |
S |
A |
-0.2426 |
|
168 |
G |
A |
-0.1987 |
|
169 |
V |
A |
0.4164 |
|
170 |
A |
A |
0.2841 |
|
171 |
T |
A |
0.1587 |
|
172 |
G |
A |
0.1109 |
|
173 |
P |
A |
0.2808 |
|
174 |
A |
A |
1.0418 |
|
175 |
V |
A |
2.3558 |
|
176 |
L |
A |
2.1584 |
|
177 |
Q |
A |
0.7346 |
|
178 |
S |
A |
0.0590 |
|
179 |
S |
A |
-0.2636 |
|
180 |
G |
A |
0.1663 |
|
181 |
L |
A |
0.2484 |
|
182 |
Y |
A |
0.7964 |
|
183 |
S |
A |
0.0000 |
|
184 |
L |
A |
0.6640 |
|
185 |
S |
A |
0.6448 |
|
186 |
S |
A |
0.0000 |
|
187 |
V |
A |
0.8588 |
|
188 |
V |
A |
0.0000 |
|
189 |
T |
A |
-0.0985 |
|
190 |
V |
A |
0.0000 |
|
191 |
P |
A |
-0.5478 |
|
192 |
S |
A |
-0.6260 |
|
193 |
S |
A |
-0.5949 |
|
194 |
S |
A |
-0.5790 |
|
195 |
L |
A |
-0.7372 |
|
196 |
G |
A |
-0.9179 |
|
197 |
T |
A |
-0.6968 |
|
198 |
Q |
A |
-0.9429 |
|
199 |
T |
A |
-1.0914 |
|
200 |
Y |
A |
0.0000 |
|
201 |
I |
A |
-1.2229 |
|
202 |
C |
A |
0.0000 |
|
203 |
N |
A |
-1.3672 |
|
204 |
V |
A |
0.0000 |
|
205 |
N |
A |
-1.8633 |
|
206 |
H |
A |
0.0000 |
|
207 |
K |
A |
-2.7755 |
|
208 |
P |
A |
-1.6034 |
|
209 |
S |
A |
-1.8269 |
|
210 |
N |
A |
-2.5717 |
|
211 |
T |
A |
-2.1274 |
|
212 |
K |
A |
-2.6359 |
|
213 |
V |
A |
-1.5122 |
|
214 |
D |
A |
-2.1513 |
|
215 |
K |
A |
-1.8435 |
|
216 |
K |
A |
-2.3847 |
|
217 |
V |
A |
0.0000 |
|
218 |
E |
A |
-2.7089 |
|
219 |
P |
A |
-2.0041 |
|
220 |
K |
A |
-2.3723 |
|