Project name: OspC-N21

Chain sequence(s)	A: MKKNTLSAILMTLFLFISCNNSGKDGNASTNSADESVKGPNLTEISKKITESNAVVLAVKEVETLLSSIDELTKAIGKKIEQNVGLGADQNHNGSLLAGAYAISTLITQKLSKLKNSEELKEKIEAAKKCSEEFTKKLKSEHADLGIAGATDDNAKKAILKTHANKDKGAKELKKLFESVESLSKAAKEMLANSVKELTSPVVAESPKKP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.1531
• Maximal score value: 2.2657
• Average score: -1.0027
• Total score value: -210.5636

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.7719
2	K	A	-0.0282
3	K	A	-0.3674
4	N	A	0.0276
5	T	A	1.1954
6	L	A	1.1698
7	S	A	0.0000
8	A	A	0.0000
9	I	A	0.7901
10	L	A	0.0000
11	M	A	0.2660
12	T	A	0.8322
13	L	A	0.0000
14	F	A	0.6893
15	L	A	1.7548
16	F	A	2.2657
17	I	A	1.2847
18	S	A	0.0000
19	C	A	0.0000
20	N	A	-0.7933
21	N	A	-1.1787
22	S	A	0.0916
23	G	A	-0.9389
24	K	A	-2.3811
25	D	A	-1.9475
26	G	A	-0.6667
27	N	A	-0.7021
28	A	A	0.3152
29	S	A	-0.4125
30	T	A	-0.8556
31	N	A	-1.6713
32	S	A	-1.9370
33	A	A	-1.7208
34	D	A	-2.6720
35	E	A	-2.2339
36	S	A	-1.5124
37	V	A	-0.0600
38	K	A	-0.8500
39	G	A	-0.1517
40	P	A	-0.5598
41	N	A	-1.1641
42	L	A	-1.1350
43	T	A	-1.3358
44	E	A	-2.1852
45	I	A	0.0000
46	S	A	-1.7093
47	K	A	-2.8965
48	K	A	-2.6096
49	I	A	-1.7772
50	T	A	-1.8477
51	E	A	-2.8159
52	S	A	-1.8914
53	N	A	-1.1561
54	A	A	-0.9539
55	V	A	0.0000
56	V	A	0.0000
57	L	A	-0.1269
58	A	A	-0.6148
59	V	A	0.0000
60	K	A	0.0000
61	E	A	-0.1950
62	V	A	0.0000
63	E	A	0.0000
64	T	A	0.0000
65	L	A	0.1136
66	L	A	0.0000
67	S	A	-0.6157
68	S	A	-0.7034
69	I	A	0.0000
70	D	A	-1.3909
71	E	A	-2.3730
72	L	A	-1.2080
73	T	A	0.0000
74	K	A	-2.3025
75	A	A	-0.9977
76	I	A	0.0000
77	G	A	0.0000
78	K	A	-1.6610
79	K	A	-0.7600
80	I	A	0.7475
81	E	A	-1.3017
82	Q	A	-1.6994
83	N	A	-1.0298
84	V	A	1.1321
85	G	A	0.2627
86	L	A	0.8308
87	G	A	-0.2604
88	A	A	-0.8514
89	D	A	-1.7560
90	Q	A	-2.7905
91	N	A	-2.5842
92	H	A	-2.0051
93	N	A	0.0000
94	G	A	0.0000
95	S	A	-0.0560
96	L	A	0.0799
97	L	A	0.0000
98	A	A	0.2179
99	G	A	0.1619
100	A	A	0.0000
101	Y	A	0.2649
102	A	A	0.4972
103	I	A	0.5587
104	S	A	0.0000
105	T	A	-0.1077
106	L	A	0.2761
107	I	A	0.0000
108	T	A	-1.3647
109	Q	A	-1.4808
110	K	A	-1.5848
111	L	A	0.0000
112	S	A	-1.9649
113	K	A	-2.6742
114	L	A	0.0000
115	K	A	-2.7459
116	N	A	-3.2712
117	S	A	-3.0361
118	E	A	-3.7362
119	E	A	-3.5435
120	L	A	0.0000
121	K	A	-3.8554
122	E	A	-3.4358
123	K	A	-2.4668
124	I	A	0.0000
125	E	A	-2.7543
126	A	A	-2.4258
127	A	A	0.0000
128	K	A	-2.7373
129	K	A	-3.1830
130	C	A	-3.0434
131	S	A	0.0000
132	E	A	-3.7210
133	E	A	-4.1531
134	F	A	0.0000
135	T	A	-2.1094
136	K	A	-3.3590
137	K	A	-2.8133
138	L	A	0.0000
139	K	A	-2.1559
140	S	A	-1.6132
141	E	A	-1.8185
142	H	A	-1.6539
143	A	A	-0.6894
144	D	A	-0.9773
145	L	A	0.0000
146	G	A	-0.2699
147	I	A	1.1608
148	A	A	0.1816
149	G	A	-0.8523
150	A	A	0.0000
151	T	A	-1.6519
152	D	A	-2.2023
153	D	A	-2.3806
154	N	A	-1.8930
155	A	A	0.0000
156	K	A	-1.9269
157	K	A	-2.0995
158	A	A	0.0000
159	I	A	0.0000
160	L	A	-1.4295
161	K	A	0.0000
162	T	A	-0.7792
163	H	A	-1.2654
164	A	A	-1.1304
165	N	A	-2.3889
166	K	A	-2.4719
167	D	A	-2.3046
168	K	A	-1.9089
169	G	A	0.0000
170	A	A	0.0000
171	K	A	-3.2092
172	E	A	-3.0912
173	L	A	0.0000
174	K	A	-2.5973
175	K	A	-2.9565
176	L	A	0.0000
177	F	A	-1.6894
178	E	A	-2.6147
179	S	A	-1.9476
180	V	A	0.0000
181	E	A	-1.8873
182	S	A	-1.5333
183	L	A	0.0000
184	S	A	0.0000
185	K	A	-2.1836
186	A	A	-1.5387
187	A	A	0.0000
188	K	A	-1.4314
189	E	A	-1.5318
190	M	A	-1.4339
191	L	A	0.0000
192	A	A	-1.3051
193	N	A	-1.9657
194	S	A	0.0000
195	V	A	-1.9036
196	K	A	-2.3364
197	E	A	-1.9103
198	L	A	0.0000
199	T	A	-1.5812
200	S	A	-1.0170
201	P	A	0.3230
202	V	A	1.5067
203	V	A	1.1963
204	A	A	-0.0029
205	E	A	-2.1374
206	S	A	-1.7553
207	P	A	-2.0078
208	K	A	-3.0979
209	K	A	-3.1867
210	P	A	-1.8434