Aggrescan3D: 2e68de120d71309

Project name: 2e68de120d71309

Status: done

submitted: 2019-09-12 12:05:49, status changed: 2019-09-23 20:56:34

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Chain sequence(s)	A: LNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFATLRREAPISFWPTIELPGFVAGNGHWALTKYDDVFYASRHPDDIFSSYPNITINDQTPELAEYFGSMIVLDDPRHQRLRSSIVSRAFTPKVVARIEAAVRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQRIFHWTNVILGFGDPDLATDFDEFMQVSADIGAYATALAEDRRVNHHDDLTSSLVEAEVDGERLSSREIASFFILLVVAGNETTRNAITHGVLALSRYPEQRDRWWSDFDGLAPTAVEEIVRWASPVVYMRRTLTQDIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGGGAHFCLGANLARREIRVAFDELRRQMPDVVATEEPARLLSQFIHGIKTLPVTWS
Distance of aggregation	10 Å
Dynamic mode	No

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Minimal score value: -4.2414
Maximal score value: 1.4467
Average score: -0.8373
Total score value: -356.6877

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
residue index	residue name	chain	Aggrescan3D score	mutation
3	L	A	0.8611
4	N	A	-0.5234
5	T	A	-0.3905
6	A	A	-0.4567
7	I	A	-0.9012
8	A	A	-0.8208
9	T	A	-0.2883
10	R	A	-0.3925
11	V	A	0.9447
12	N	A	-0.5024
13	G	A	-0.5976
14	T	A	-0.3307
15	P	A	-0.9622
16	P	A	-0.8762
17	P	A	-1.1871
18	E	A	-1.8716
19	V	A	0.0000
20	P	A	-0.6950
21	I	A	-0.1834
22	A	A	-0.5102
23	D	A	-1.6525
24	I	A	0.0000
25	E	A	-1.5541
26	L	A	0.0000
27	G	A	-0.8276
28	S	A	-1.1597
29	L	A	-0.9101
30	D	A	-1.6302
31	F	A	0.0000
32	W	A	0.0000
33	A	A	-0.7012
34	L	A	-0.6463
35	D	A	-1.8042
36	D	A	-1.4119
37	D	A	-1.3472
38	V	A	-0.9214
39	R	A	0.0000
40	D	A	-0.8801
41	G	A	0.0000
42	A	A	0.0000
43	F	A	0.0000
44	A	A	-1.0222
45	T	A	-1.2305
46	L	A	0.0000
47	R	A	0.0000
48	R	A	-2.8170
49	E	A	-2.5232
50	A	A	-1.0903
51	P	A	-1.2597
52	I	A	0.0000
53	S	A	0.5093
54	F	A	1.4467
55	W	A	0.0000
56	P	A	-0.6838
57	T	A	0.0000
58	I	A	0.0000
59	E	A	-1.7130
60	L	A	-0.8574
61	P	A	-1.1004
62	G	A	-0.9150
63	F	A	-0.1072
64	V	A	-0.1518
65	A	A	-0.9926
66	G	A	-1.3257
67	N	A	-1.7396
68	G	A	-0.6924
69	H	A	0.0000
70	W	A	0.6456
71	A	A	0.0000
72	L	A	0.0000
73	T	A	0.0000
74	K	A	-1.3120
75	Y	A	0.0000
76	D	A	-1.7719
77	D	A	0.0000
78	V	A	0.0000
79	F	A	-0.2970
80	Y	A	-0.3968
81	A	A	0.0000
82	S	A	0.0000
83	R	A	-1.5080
84	H	A	-1.4463
85	P	A	-1.5828
86	D	A	-2.3685
87	I	A	-1.3769
88	F	A	0.0000
89	S	A	0.0000
90	S	A	0.0000
91	Y	A	1.2355
92	P	A	0.5919
93	N	A	0.0000
94	I	A	0.0000
95	T	A	-0.1523
96	I	A	0.0000
97	N	A	-0.7790
98	D	A	-0.8705
99	Q	A	-0.5924
100	T	A	-1.0247
101	P	A	-1.4999
102	E	A	-2.3576
103	L	A	0.0000
104	A	A	-1.4440
105	E	A	-2.2925
106	Y	A	-0.9572
107	F	A	-0.3759
108	G	A	-0.3805
109	S	A	0.0000
110	M	A	0.0000
111	I	A	0.6156
112	V	A	0.0000
113	L	A	-0.0314
114	D	A	-1.3879
115	D	A	-2.6738
116	P	A	-2.1857
117	R	A	-2.4854
118	H	A	0.0000
119	Q	A	-2.9115
120	R	A	-3.5269
121	L	A	0.0000
122	R	A	-1.7194
123	S	A	-1.5195
124	I	A	-1.2764
125	V	A	0.0000
126	S	A	-1.0726
127	R	A	-2.0796
128	A	A	-1.1937
129	F	A	0.0000
130	T	A	-1.2149
131	P	A	-1.5642
132	K	A	-2.3036
133	V	A	-1.6842
134	V	A	0.0000
135	A	A	-1.6557
136	R	A	-2.2639
137	I	A	-1.1942
138	E	A	-1.8547
139	A	A	-1.3571
140	A	A	-1.5138
141	V	A	0.0000
142	R	A	-2.1979
143	D	A	-3.0843
144	R	A	-2.2579
145	A	A	0.0000
146	H	A	-2.5574
147	R	A	-2.7673
148	L	A	0.0000
149	V	A	0.0000
150	S	A	-1.0165
151	S	A	-0.8899
152	M	A	0.0000
153	I	A	-0.8594
154	A	A	-0.7881
155	N	A	-1.7851
156	N	A	-2.1059
157	P	A	-2.0355
158	D	A	-3.1130
159	R	A	-3.1460
160	Q	A	-2.3410
161	A	A	0.0000
162	D	A	-0.6988
163	L	A	0.0000
164	V	A	0.0000
165	S	A	-0.5362
166	E	A	-0.6083
167	L	A	0.0000
168	A	A	0.0000
169	G	A	0.0000
170	P	A	-0.4670
171	L	A	0.0000
172	P	A	0.0000
173	L	A	0.0000
174	Q	A	-1.2643
175	I	A	0.0000
176	I	A	0.0000
177	C	A	0.0000
178	D	A	-2.0159
179	M	A	-0.9941
180	M	A	0.0000
181	G	A	-1.4778
182	I	A	0.0000
183	P	A	-1.4934
184	K	A	-2.5918
185	A	A	-1.5451
186	D	A	-1.8832
187	H	A	-2.3174
188	Q	A	-2.6639
189	R	A	-2.9868
190	I	A	0.0000
191	F	A	-1.3000
192	H	A	-1.5810
193	W	A	0.0000
194	T	A	0.0000
195	N	A	-0.4095
196	V	A	0.0000
197	I	A	0.0000
198	L	A	0.3214
199	G	A	0.0000
200	F	A	0.0000
201	G	A	0.0000
202	D	A	0.0000
203	P	A	-1.1882
204	D	A	-1.7279
205	L	A	-0.9862
206	A	A	0.0000
207	T	A	-1.5946
208	D	A	-2.6319
209	F	A	-1.9795
210	D	A	-3.1045
211	E	A	-2.8048
212	F	A	0.0000
213	M	A	-1.8386
214	Q	A	-2.0951
215	V	A	0.0000
216	S	A	0.0000
217	A	A	-0.8704
218	D	A	-0.9887
219	I	A	0.0000
220	G	A	0.0000
221	A	A	-0.0520
222	Y	A	0.0197
223	A	A	0.0000
224	T	A	-0.8735
225	A	A	-1.1489
226	L	A	0.0000
227	A	A	0.0000
228	E	A	-3.1598
229	D	A	-3.2870
230	R	A	-3.4855
231	R	A	-3.3694
232	V	A	-1.0311
233	N	A	-2.6347
234	H	A	-3.1889
235	H	A	-3.0163
236	D	A	-2.8176
237	D	A	-1.8896
238	L	A	0.0000
239	T	A	0.0000
240	S	A	0.0000
241	S	A	-1.7076
242	L	A	0.0000
243	V	A	0.0000
244	E	A	-2.9447
245	A	A	-2.6017
246	E	A	-4.2414
247	V	A	0.0000
248	D	A	-3.9053
249	G	A	-3.0241
250	E	A	-3.8750
251	R	A	-3.5487
252	L	A	-2.0978
253	S	A	-0.9985
254	S	A	-1.1819
255	R	A	-1.3854
256	E	A	-1.0069
257	I	A	0.0000
258	A	A	0.0000
259	S	A	0.0000
260	F	A	0.0000
261	F	A	0.0000
262	I	A	0.0000
263	L	A	0.4170
264	L	A	0.0000
265	V	A	0.0000
266	V	A	0.2758
267	A	A	0.2289
268	G	A	-0.0308
269	N	A	0.0000
270	E	A	0.0000
271	T	A	-0.0289
272	T	A	0.0000
273	R	A	-0.2664
274	N	A	0.0000
275	A	A	0.0000
276	I	A	0.0000
277	T	A	0.0000
278	H	A	0.0000
279	G	A	0.0000
280	V	A	0.0000
281	L	A	0.0000
282	A	A	0.0000
283	L	A	0.0000
284	S	A	0.0000
285	R	A	-0.7182
286	Y	A	0.0000
287	P	A	-1.9786
288	E	A	-3.2722
289	Q	A	-2.5653
290	R	A	-2.4721
291	D	A	-3.8365
292	R	A	-3.8017
293	W	A	0.0000
294	W	A	-2.4325
295	S	A	-2.3994
296	D	A	-3.1672
297	F	A	0.0000
298	D	A	-2.6502
299	G	A	-1.8737
300	L	A	-1.4839
301	A	A	0.0000
302	P	A	-1.0247
303	T	A	-0.6814
304	A	A	0.0000
305	V	A	0.0000
306	E	A	-0.8213
307	E	A	0.0000
308	I	A	0.0000
309	V	A	0.0000
310	R	A	0.0000
311	W	A	0.0669
312	A	A	0.0000
313	S	A	0.0000
314	P	A	0.0000
315	V	A	0.3079
316	V	A	0.0000
317	Y	A	0.0000
318	M	A	0.1997
319	R	A	0.0000
320	R	A	0.0000
321	T	A	-0.0418
322	L	A	0.0000
323	T	A	-1.1065
324	Q	A	-1.9432
325	D	A	-2.8193
326	I	A	-2.0669
327	E	A	-3.1095
328	L	A	-1.8188
329	R	A	-2.1510
330	G	A	-1.9252
331	T	A	-1.9310
332	K	A	-3.0107
333	M	A	0.0000
334	A	A	-1.7678
335	A	A	-1.3040
336	G	A	-1.2425
337	D	A	-1.1930
338	K	A	0.0000
339	V	A	0.0000
340	S	A	0.0000
341	L	A	0.0000
342	W	A	0.0000
343	Y	A	0.0000
344	C	A	0.0000
345	S	A	0.0000
346	A	A	0.0000
347	N	A	0.0000
348	R	A	0.0000
349	D	A	0.0000
350	E	A	-1.7563
351	S	A	-1.6641
352	K	A	-2.2873
353	F	A	0.0000
354	A	A	-1.3573
355	D	A	-2.2353
356	P	A	0.0000
357	W	A	-0.8578
358	T	A	-0.7292
359	F	A	0.0000
360	D	A	-1.4738
361	L	A	0.0000
362	A	A	-0.9691
363	R	A	-1.3393
364	N	A	-1.7120
365	P	A	-1.2257
366	N	A	-1.0874
367	P	A	-0.7871
368	H	A	-0.4208
369	L	A	0.0000
370	G	A	0.0000
371	F	A	0.5345
372	G	A	0.3870
373	G	A	0.0000
374	G	A	-0.0544
375	G	A	-0.5805
376	A	A	-0.7489
377	H	A	-0.1821
378	F	A	0.7030
379	C	A	0.7014
380	L	A	0.3980
381	G	A	-0.0149
382	A	A	0.0000
383	N	A	-0.8181
384	L	A	0.0000
385	A	A	0.0000
386	R	A	-1.3079
387	R	A	-1.2627
388	E	A	0.0000
389	I	A	0.0000
390	R	A	-1.4701
391	V	A	0.0000
392	A	A	0.0000
393	F	A	0.0000
394	D	A	-1.4430
395	E	A	0.0000
396	L	A	0.0000
397	R	A	-1.6008
398	R	A	-1.9795
399	Q	A	-1.4972
400	M	A	0.0000
401	P	A	-1.3956
402	D	A	-0.8637
403	V	A	0.0000
404	V	A	0.0000
405	A	A	0.0000
406	T	A	-1.3221
407	E	A	-2.6518
408	E	A	-2.7358
409	P	A	-1.6467
410	A	A	-0.9753
411	R	A	-1.0789
412	L	A	-0.3161
413	L	A	-0.1805
414	S	A	-0.0315
415	Q	A	0.0756
416	F	A	0.2735
417	I	A	0.0000
418	H	A	-0.1058
419	G	A	0.0000
420	I	A	0.0000
421	K	A	-0.7776
422	T	A	-0.9038
423	L	A	0.0000
424	P	A	-1.1572
425	V	A	0.0000
426	T	A	-1.2219
427	W	A	0.0000
428	S	A	-0.6070

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