| Chain sequence(s) |
A: KFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE B: KFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATE |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 3 | K | A | -1.3076 | |
| 4 | F | A | -0.0470 | |
| 5 | V | A | 0.9063 | |
| 6 | I | A | 0.1282 | |
| 7 | R | A | -0.2040 | |
| 8 | P | A | -0.5484 | |
| 9 | A | A | -0.2566 | |
| 10 | T | A | 0.0264 | |
| 11 | A | A | 0.0215 | |
| 12 | A | A | 0.0397 | |
| 13 | D | A | 0.0000 | |
| 14 | C | A | 0.0000 | |
| 15 | S | A | -0.6587 | |
| 16 | D | A | -0.6063 | |
| 17 | I | A | 0.0000 | |
| 18 | L | A | -0.4753 | |
| 19 | R | A | -0.7914 | |
| 20 | L | A | 0.0000 | |
| 21 | I | A | -0.4600 | |
| 22 | K | A | -1.4245 | |
| 23 | E | A | -1.2720 | |
| 24 | L | A | -0.5359 | |
| 25 | A | A | -1.6964 | |
| 26 | K | A | -2.1129 | |
| 27 | Y | A | -0.1381 | |
| 28 | E | A | -0.5781 | |
| 29 | Y | A | 0.5894 | |
| 30 | M | A | -0.0807 | |
| 31 | E | A | -2.3572 | |
| 32 | E | A | -2.9168 | |
| 33 | Q | A | -1.8909 | |
| 34 | V | A | -0.0688 | |
| 35 | I | A | 1.7329 | |
| 36 | L | A | 0.7982 | |
| 37 | T | A | -0.5609 | |
| 38 | E | A | -2.1101 | |
| 39 | K | A | -2.9359 | |
| 40 | D | A | -2.2730 | |
| 41 | L | A | 0.0000 | |
| 42 | L | A | -1.6594 | |
| 43 | E | A | -3.0878 | |
| 44 | D | A | -2.3298 | |
| 45 | G | A | 0.0000 | |
| 46 | F | A | -0.5235 | |
| 47 | G | A | -1.8361 | |
| 48 | E | A | -2.5236 | |
| 49 | H | A | -1.8306 | |
| 50 | P | A | -0.5137 | |
| 51 | F | A | 0.9905 | |
| 52 | Y | A | 0.0000 | |
| 53 | H | A | -0.0110 | |
| 54 | C | A | 0.0000 | |
| 55 | L | A | 0.0000 | |
| 56 | V | A | 0.0000 | |
| 57 | A | A | 0.0000 | |
| 58 | E | A | -0.4202 | |
| 59 | V | A | 0.0000 | |
| 60 | P | A | -1.9505 | |
| 61 | K | A | -2.9016 | |
| 62 | E | A | -3.0198 | |
| 63 | H | A | -2.5002 | |
| 64 | W | A | -1.6285 | |
| 65 | T | A | 0.0000 | |
| 66 | P | A | -1.2712 | |
| 67 | E | A | -2.0429 | |
| 68 | G | A | -1.7342 | |
| 69 | H | A | -1.2591 | |
| 70 | S | A | -1.2269 | |
| 71 | I | A | 0.0000 | |
| 72 | V | A | 0.0000 | |
| 73 | G | A | 0.0000 | |
| 74 | F | A | 0.0000 | |
| 75 | A | A | 0.0000 | |
| 76 | M | A | -0.3972 | |
| 77 | Y | A | 0.0000 | |
| 78 | Y | A | 0.8591 | |
| 79 | F | A | 1.1455 | |
| 80 | T | A | 0.6515 | |
| 81 | Y | A | 1.0592 | |
| 82 | D | A | 0.4687 | |
| 83 | P | A | 0.5614 | |
| 84 | W | A | 1.4813 | |
| 85 | I | A | 1.3386 | |
| 86 | G | A | 0.1584 | |
| 87 | K | A | -0.5944 | |
| 88 | L | A | 0.0000 | |
| 89 | L | A | 0.0000 | |
| 90 | Y | A | 0.3653 | |
| 91 | L | A | 0.0000 | |
| 92 | E | A | -0.9265 | |
| 93 | D | A | -0.7182 | |
| 94 | F | A | 0.0387 | |
| 95 | F | A | 0.0000 | |
| 96 | V | A | 0.0000 | |
| 97 | M | A | -0.8207 | |
| 98 | S | A | -1.4581 | |
| 99 | D | A | -2.1666 | |
| 100 | Y | A | 0.0000 | |
| 101 | R | A | -1.7959 | |
| 102 | G | A | -0.8743 | |
| 103 | F | A | -0.0087 | |
| 104 | G | A | -0.4336 | |
| 105 | I | A | 0.0000 | |
| 106 | G | A | -0.6881 | |
| 107 | S | A | -0.9916 | |
| 108 | E | A | -1.3147 | |
| 109 | I | A | 0.0000 | |
| 110 | L | A | -1.2597 | |
| 111 | K | A | -2.4754 | |
| 112 | N | A | -1.8009 | |
| 113 | L | A | 0.0000 | |
| 114 | S | A | -1.3539 | |
| 115 | Q | A | -1.9984 | |
| 116 | V | A | -1.2812 | |
| 117 | A | A | -0.9390 | |
| 118 | M | A | -0.8933 | |
| 119 | R | A | -2.1164 | |
| 120 | C | A | -1.5868 | |
| 121 | R | A | -2.3840 | |
| 122 | C | A | -0.8874 | |
| 123 | S | A | -0.4564 | |
| 124 | S | A | -0.3579 | |
| 125 | M | A | 0.0171 | |
| 126 | H | A | 0.0987 | |
| 127 | F | A | 0.6388 | |
| 128 | L | A | 1.5836 | |
| 129 | V | A | 0.7953 | |
| 130 | A | A | -0.2309 | |
| 131 | E | A | -1.6021 | |
| 132 | W | A | -0.5627 | |
| 133 | N | A | -1.2169 | |
| 134 | E | A | -1.9851 | |
| 135 | P | A | -1.0815 | |
| 136 | S | A | -0.8752 | |
| 137 | I | A | -1.1404 | |
| 138 | N | A | -1.8354 | |
| 139 | F | A | -1.2223 | |
| 140 | Y | A | -1.9539 | |
| 141 | K | A | -3.2243 | |
| 142 | R | A | -3.4344 | |
| 143 | R | A | -3.3672 | |
| 144 | G | A | -2.4253 | |
| 145 | A | A | -1.8616 | |
| 146 | S | A | -1.7824 | |
| 147 | D | A | -1.8123 | |
| 148 | L | A | -1.2295 | |
| 149 | S | A | -1.4055 | |
| 150 | S | A | -2.1793 | |
| 151 | E | A | -2.8697 | |
| 152 | E | A | -2.8341 | |
| 153 | G | A | -1.8328 | |
| 154 | W | A | -0.2451 | |
| 155 | R | A | -0.3153 | |
| 156 | L | A | 1.6524 | |
| 157 | F | A | 1.7588 | |
| 158 | K | A | -0.5209 | |
| 159 | I | A | -0.3603 | |
| 160 | D | A | -2.3204 | |
| 161 | K | A | -2.4587 | |
| 162 | E | A | -2.0633 | |
| 163 | Y | A | -0.0200 | |
| 164 | L | A | 0.3595 | |
| 165 | L | A | -0.0919 | |
| 166 | K | A | -1.2753 | |
| 167 | M | A | -0.2866 | |
| 168 | A | A | -0.1466 | |
| 169 | T | A | -1.1482 | |
| 170 | E | A | -2.7421 | |
| 171 | E | A | -2.7704 | |
| 3 | K | B | -1.4353 | |
| 4 | F | B | 0.0438 | |
| 5 | V | B | 0.9131 | |
| 6 | I | B | 0.2137 | |
| 7 | R | B | -0.2144 | |
| 8 | P | B | -0.5030 | |
| 9 | A | B | -0.1723 | |
| 10 | T | B | 0.0509 | |
| 11 | A | B | -0.0038 | |
| 12 | A | B | 0.0397 | |
| 13 | D | B | 0.0000 | |
| 14 | C | B | 0.0000 | |
| 15 | S | B | -0.7645 | |
| 16 | D | B | -0.6602 | |
| 17 | I | B | 0.0000 | |
| 18 | L | B | 0.0000 | |
| 19 | R | B | -0.8555 | |
| 20 | L | B | 0.0000 | |
| 21 | I | B | -0.5796 | |
| 22 | K | B | -1.4110 | |
| 23 | E | B | -1.1428 | |
| 24 | L | B | -0.6065 | |
| 25 | A | B | -1.8904 | |
| 26 | K | B | -2.1686 | |
| 27 | Y | B | -0.1688 | |
| 28 | E | B | -1.3961 | |
| 29 | Y | B | 0.2615 | |
| 30 | M | B | -0.2887 | |
| 31 | E | B | -2.5122 | |
| 32 | E | B | -2.9292 | |
| 33 | Q | B | -2.2043 | |
| 34 | V | B | -0.0531 | |
| 35 | I | B | 1.7537 | |
| 36 | L | B | 0.7589 | |
| 37 | T | B | -0.5922 | |
| 38 | E | B | -2.2078 | |
| 39 | K | B | -2.8884 | |
| 40 | D | B | -2.0429 | |
| 41 | L | B | 0.0000 | |
| 42 | L | B | -1.5630 | |
| 43 | E | B | -2.9189 | |
| 44 | D | B | -2.0555 | |
| 45 | G | B | 0.0000 | |
| 46 | F | B | -0.3600 | |
| 47 | G | B | -1.6734 | |
| 48 | E | B | -2.4581 | |
| 49 | H | B | -1.7648 | |
| 50 | P | B | -0.4352 | |
| 51 | F | B | 1.1174 | |
| 52 | Y | B | 0.0000 | |
| 53 | H | B | 0.1837 | |
| 54 | C | B | 0.0000 | |
| 55 | L | B | 0.0000 | |
| 56 | V | B | 0.0000 | |
| 57 | A | B | 0.0000 | |
| 58 | E | B | -0.3123 | |
| 59 | V | B | 0.0000 | |
| 60 | P | B | -1.8880 | |
| 61 | K | B | -2.8337 | |
| 62 | E | B | -3.1088 | |
| 63 | H | B | -2.3160 | |
| 64 | W | B | -1.5625 | |
| 65 | T | B | 0.0000 | |
| 66 | P | B | -1.2669 | |
| 67 | E | B | -2.1095 | |
| 68 | G | B | -1.8432 | |
| 69 | H | B | -1.2983 | |
| 70 | S | B | -1.1272 | |
| 71 | I | B | 0.0000 | |
| 72 | V | B | 0.0000 | |
| 73 | G | B | 0.0000 | |
| 74 | F | B | 0.0000 | |
| 75 | A | B | 0.0000 | |
| 76 | M | B | -0.3291 | |
| 77 | Y | B | 0.2597 | |
| 78 | Y | B | 0.9529 | |
| 79 | F | B | 1.2566 | |
| 80 | T | B | 0.7269 | |
| 81 | Y | B | 1.1201 | |
| 82 | D | B | 0.4855 | |
| 83 | P | B | 0.5503 | |
| 84 | W | B | 1.4568 | |
| 85 | I | B | 1.2788 | |
| 86 | G | B | 0.1926 | |
| 87 | K | B | -0.4738 | |
| 88 | L | B | 0.0000 | |
| 89 | L | B | 0.0000 | |
| 90 | Y | B | 0.4255 | |
| 91 | L | B | 0.0000 | |
| 92 | E | B | -0.9712 | |
| 93 | D | B | -0.6685 | |
| 94 | F | B | -0.0759 | |
| 95 | F | B | 0.0000 | |
| 96 | V | B | 0.0000 | |
| 97 | M | B | -0.7687 | |
| 98 | S | B | -1.3285 | |
| 99 | D | B | -2.0659 | |
| 100 | Y | B | 0.0000 | |
| 101 | R | B | -1.3523 | |
| 102 | G | B | -0.6451 | |
| 103 | F | B | 0.4312 | |
| 104 | G | B | -0.0310 | |
| 105 | I | B | 0.0000 | |
| 106 | G | B | -0.5987 | |
| 107 | S | B | -0.7955 | |
| 108 | E | B | -1.2060 | |
| 109 | I | B | 0.0000 | |
| 110 | L | B | 0.0000 | |
| 111 | K | B | -2.3857 | |
| 112 | N | B | -1.5980 | |
| 113 | L | B | 0.0000 | |
| 114 | S | B | -1.2022 | |
| 115 | Q | B | -1.5381 | |
| 116 | V | B | -1.1046 | |
| 117 | A | B | 0.0000 | |
| 118 | M | B | -0.7353 | |
| 119 | R | B | -2.0289 | |
| 120 | C | B | -1.5032 | |
| 121 | R | B | -2.2546 | |
| 122 | C | B | -0.8571 | |
| 123 | S | B | -0.4109 | |
| 124 | S | B | -0.3166 | |
| 125 | M | B | 0.0888 | |
| 126 | H | B | 0.2852 | |
| 127 | F | B | 0.6178 | |
| 128 | L | B | 1.4606 | |
| 129 | V | B | 0.6619 | |
| 130 | A | B | -0.1764 | |
| 131 | E | B | -1.5485 | |
| 132 | W | B | -0.3417 | |
| 133 | N | B | -1.2163 | |
| 134 | E | B | -2.0076 | |
| 135 | P | B | -1.1792 | |
| 136 | S | B | -1.0088 | |
| 137 | I | B | -1.5438 | |
| 138 | N | B | -2.0622 | |
| 139 | F | B | -1.5686 | |
| 140 | Y | B | 0.0000 | |
| 141 | K | B | -3.5881 | |
| 142 | R | B | -3.6355 | |
| 143 | R | B | -3.4652 | |
| 144 | G | B | -2.5527 | |
| 145 | A | B | -2.1091 | |
| 146 | S | B | -2.0900 | |
| 147 | D | B | -2.3314 | |
| 148 | L | B | -1.4943 | |
| 149 | S | B | -1.6980 | |
| 150 | S | B | -2.3687 | |
| 151 | E | B | -3.0283 | |
| 152 | E | B | -2.9401 | |
| 153 | G | B | -1.9076 | |
| 154 | W | B | -0.4508 | |
| 155 | R | B | -0.6373 | |
| 156 | L | B | 1.0248 | |
| 157 | F | B | 1.3781 | |
| 158 | K | B | -0.7299 | |
| 159 | I | B | -0.6420 | |
| 160 | D | B | -2.5988 | |
| 161 | K | B | -2.7135 | |
| 162 | E | B | -2.2013 | |
| 163 | Y | B | -0.6634 | |
| 164 | L | B | 0.1254 | |
| 165 | L | B | -0.0658 | |
| 166 | K | B | -0.8754 | |
| 167 | M | B | 0.1497 | |
| 168 | A | B | 0.2435 | |
| 169 | T | B | -0.5499 | |
| 170 | E | B | -1.5813 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine