Project name: AP_mix5%_2osl

Chain sequence(s)	A: QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.662
• Maximal score value: 1.6844
• Average score: -0.6459
• Total score value: -280.9525

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.0428
2	I	A	-0.0292
3	V	A	1.1576
4	L	A	0.0000
5	S	A	-0.5761
6	Q	A	-0.8912
7	S	A	-0.3310
8	P	A	0.2903
9	A	A	0.6102
10	I	A	1.6844
11	L	A	0.7291
12	S	A	-0.2856
13	A	A	0.0000
14	S	A	-2.1003
15	P	A	-2.1992
16	G	A	-2.5086
17	E	A	-3.1335
18	K	A	-2.9817
19	V	A	-1.2989
20	T	A	-0.3711
21	M	A	0.0000
22	T	A	-0.6830
23	C	A	0.0000
24	R	A	-1.8550
25	A	A	0.0000
26	S	A	-0.3369
27	S	A	-0.5515
28	S	A	-0.7237
29	V	A	0.0000
30	S	A	-0.1839
31	Y	A	0.1841
32	I	A	0.0000
33	H	A	0.0000
34	W	A	0.0000
35	F	A	0.0000
36	Q	A	0.0000
37	Q	A	-0.8358
38	K	A	0.0000
39	P	A	-0.8328
40	G	A	-0.6242
41	S	A	-0.7380
42	S	A	-0.6325
43	P	A	0.0000
44	K	A	-1.8562
45	P	A	0.0000
46	W	A	0.0000
47	I	A	0.0000
48	Y	A	-0.1200
49	A	A	-0.2146
50	T	A	-0.3433
51	S	A	-0.6862
52	N	A	-1.1149
53	L	A	-0.0283
54	A	A	0.0000
55	S	A	-0.6906
56	G	A	-0.4229
57	V	A	-0.0002
58	P	A	0.6913
59	V	A	1.4013
60	R	A	-0.3490
61	F	A	0.0000
62	S	A	-0.1224
63	G	A	-0.5228
64	S	A	-0.6169
65	G	A	-0.7324
66	S	A	-0.7359
67	G	A	-0.7807
68	T	A	-1.0536
69	S	A	-1.2395
70	Y	A	0.0000
71	S	A	-0.6168
72	L	A	0.0000
73	T	A	-0.7275
74	I	A	0.0000
75	S	A	-1.9893
76	R	A	-3.1698
77	V	A	0.0000
78	E	A	-2.5980
79	A	A	0.0000
80	E	A	-2.6870
81	D	A	0.0000
82	A	A	-1.5560
83	A	A	0.0000
84	T	A	-0.2720
85	Y	A	0.0000
86	Y	A	-0.1637
87	C	A	0.0000
88	Q	A	0.0000
89	Q	A	0.0000
90	W	A	0.0000
91	T	A	-0.4648
92	S	A	-1.0217
93	N	A	-1.5760
94	P	A	-1.4708
95	P	A	0.0000
96	T	A	-0.0431
97	F	A	0.3277
98	G	A	0.0000
99	G	A	-0.7091
100	G	A	-0.2889
101	T	A	0.0000
102	K	A	-0.2502
103	L	A	0.0000
104	E	A	-1.1057
105	I	A	0.0000
106	K	A	-2.0420
107	R	A	-1.2738
108	T	A	-0.1836
109	V	A	0.4634
110	A	A	0.0343
111	A	A	-0.1924
112	P	A	0.0000
113	S	A	-0.2103
114	V	A	0.0000
115	F	A	0.0880
116	I	A	0.0405
117	F	A	0.0000
118	P	A	-0.4405
119	P	A	0.0000
120	S	A	-1.4313
121	D	A	-2.6349
122	E	A	-2.3042
123	Q	A	0.0000
124	L	A	-1.6633
125	K	A	-2.0534
126	S	A	-1.4110
127	G	A	-1.2807
128	T	A	-0.9216
129	A	A	0.0000
130	S	A	0.0000
131	V	A	0.0000
132	V	A	0.0000
133	C	A	0.0000
134	L	A	0.0000
135	L	A	0.0000
136	N	A	0.0000
137	N	A	-1.1272
138	F	A	0.0000
139	Y	A	0.0000
140	P	A	-1.8845
141	R	A	-3.1006
142	E	A	-3.3221
143	A	A	-2.4961
144	K	A	-2.6130
145	V	A	-1.4243
146	Q	A	-0.8280
147	W	A	0.0000
148	K	A	-0.7628
149	V	A	0.0000
150	D	A	-2.0571
151	N	A	-1.6974
152	A	A	-0.4742
153	L	A	0.2491
154	Q	A	-0.2642
155	S	A	-0.5951
156	G	A	-0.9670
157	N	A	-0.7985
158	S	A	-0.9324
159	Q	A	-2.0190
160	E	A	-2.1580
161	S	A	-1.0541
162	V	A	-0.8193
163	T	A	-0.9012
164	E	A	-1.7343
165	Q	A	0.0000
166	D	A	-2.2028
167	S	A	-2.4247
168	K	A	-2.8151
169	D	A	-1.9805
170	S	A	0.0000
171	T	A	0.0000
172	Y	A	0.0000
173	S	A	0.0000
174	L	A	0.0000
175	S	A	0.0000
176	S	A	0.0000
177	T	A	-0.2215
178	L	A	0.7196
179	T	A	0.1188
180	L	A	-0.3509
181	S	A	-1.0972
182	K	A	-2.0570
183	A	A	-1.7636
184	D	A	-2.3395
185	Y	A	0.0000
186	E	A	-3.6620
187	K	A	-3.5999
188	H	A	-3.1760
189	K	A	-3.5285
190	V	A	0.0000
191	Y	A	0.0000
192	A	A	-0.6589
193	C	A	0.0000
194	E	A	-0.7571
195	V	A	0.0000
196	T	A	-1.2678
197	H	A	0.0000
198	Q	A	-1.7610
199	G	A	-0.3721
200	L	A	-0.2491
201	S	A	-0.4694
202	S	A	-0.4341
203	P	A	-0.5377
204	V	A	0.1043
205	T	A	-0.2840
206	K	A	-0.3852
207	S	A	-0.5201
208	F	A	-1.1100
209	N	A	-2.1925
210	R	A	-2.8040
211	G	A	-2.4195
212	E	A	-2.7753
1	Q	A	-1.0444
2	V	A	-0.0547
3	Q	A	-1.3213
4	L	A	0.0000
5	Q	A	-1.9261
6	Q	A	-1.0918
7	P	A	-0.8389
8	G	A	-0.9624
9	A	A	-0.7164
10	E	A	-0.9163
11	L	A	-0.2588
12	V	A	0.0000
13	K	A	-1.6580
14	P	A	-1.2635
15	G	A	-1.1446
16	A	A	-0.9504
17	S	A	-1.1687
18	V	A	0.0000
19	K	A	-2.0877
20	M	A	0.0000
21	S	A	-0.9220
22	C	A	0.0000
23	K	A	-1.5617
24	A	A	0.0000
25	S	A	-0.8722
26	G	A	-0.6100
27	Y	A	-0.1313
28	T	A	-0.1469
29	F	A	0.0000
30	T	A	-0.6958
31	S	A	-0.1807
32	Y	A	0.3191
33	N	A	-0.2199
34	M	A	0.0000
35	H	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	K	A	0.0000
39	Q	A	-0.4111
40	T	A	0.0000
41	P	A	-0.8907
42	G	A	-1.2774
43	R	A	-1.9070
44	G	A	-1.0991
45	L	A	0.0000
46	E	A	-0.6943
47	W	A	0.0000
48	I	A	0.0000
49	G	A	0.0000
50	A	A	0.0000
51	I	A	0.0000
52	Y	A	-0.7409
53	P	A	0.0000
54	G	A	-1.4314
55	N	A	-2.0382
56	G	A	-1.9367
57	D	A	-2.3878
58	T	A	-1.1502
59	S	A	-0.7963
60	Y	A	-0.9617
61	N	A	0.0000
62	Q	A	-2.5781
63	K	A	-2.7664
64	F	A	0.0000
65	K	A	-2.5558
66	G	A	-1.7999
67	K	A	-1.5940
68	A	A	0.0000
69	T	A	-0.8544
70	L	A	0.0000
71	T	A	-0.6588
72	A	A	-0.9811
73	D	A	-1.7259
74	K	A	-2.2007
75	S	A	-1.2933
76	S	A	-1.1230
77	S	A	-1.2121
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.6075
81	M	A	0.0000
82	Q	A	-1.5092
83	L	A	0.0000
84	S	A	-0.9348
85	S	A	-0.8260
86	L	A	0.0000
87	T	A	-1.2103
88	S	A	-1.3876
89	E	A	-2.0992
90	D	A	0.0000
91	S	A	-0.6675
92	A	A	0.0000
93	V	A	0.2575
94	Y	A	0.0000
95	Y	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	S	A	0.0000
100	T	A	0.6302
101	Y	A	1.3196
102	Y	A	1.4941
103	G	A	0.4117
104	G	A	0.3155
105	D	A	0.5784
106	W	A	0.8592
107	Y	A	0.0000
108	F	A	0.0000
109	N	A	-0.5252
110	V	A	-0.3470
111	W	A	0.0000
112	G	A	0.0000
113	A	A	-0.6697
114	G	A	-0.3695
115	T	A	0.0000
116	T	A	-0.1424
117	V	A	0.0000
118	T	A	-0.5115
119	V	A	0.0000
120	S	A	-0.6007
121	A	A	-0.5589
122	A	A	-0.4230
123	S	A	-0.6483
124	T	A	-0.9724
125	K	A	-1.3337
126	G	A	-1.4077
127	P	A	-0.6249
128	S	A	-0.4381
129	V	A	0.0000
130	F	A	0.0000
131	P	A	0.0000
132	L	A	0.0000
133	A	A	-1.1536
134	P	A	0.0000
135	S	A	-1.2597
136	S	A	-1.1894
137	K	A	-1.1660
138	S	A	-0.7163
139	T	A	-0.6558
140	S	A	-0.6963
141	G	A	-0.7902
142	G	A	-0.7540
143	T	A	-0.5429
144	A	A	-0.3911
145	A	A	0.0000
146	L	A	0.0000
147	G	A	0.0000
148	C	A	0.0000
149	L	A	0.0000
150	V	A	0.0000
151	K	A	0.0000
152	D	A	-0.4920
153	Y	A	0.0000
154	F	A	0.0000
155	P	A	0.0000
156	E	A	-0.4197
157	P	A	-0.6784
158	V	A	-0.2929
159	T	A	-0.4463
160	V	A	-0.0681
161	S	A	-0.3874
162	W	A	0.0000
163	N	A	-0.7968
164	S	A	-0.6567
165	G	A	-0.5406
166	A	A	-0.2672
167	L	A	-0.0437
168	T	A	-0.2174
169	S	A	-0.2213
170	G	A	-0.3117
171	V	A	0.1177
172	H	A	-0.2843
173	T	A	-0.0086
174	F	A	0.0000
175	P	A	-0.4266
176	A	A	0.3257
177	V	A	0.6111
178	L	A	1.5354
179	Q	A	0.2535
180	S	A	-0.0580
181	S	A	-0.2422
182	G	A	0.0104
183	L	A	0.1305
184	Y	A	0.5429
185	S	A	0.4428
186	L	A	0.3501
187	S	A	0.0496
188	S	A	0.0000
189	V	A	0.0000
190	V	A	0.0000
191	T	A	-0.2170
192	V	A	0.0000
193	P	A	-0.4703
194	S	A	-0.5183
195	S	A	-0.5907
196	S	A	0.0000
197	L	A	-0.8282
198	G	A	-0.9722
199	T	A	-0.8315
200	Q	A	-1.2871
201	T	A	-1.1311
202	Y	A	-0.8048
203	I	A	-1.1919
204	C	A	0.0000
205	N	A	-1.4547
206	V	A	0.0000
207	N	A	-1.6979
208	H	A	0.0000
209	K	A	-2.7375
210	P	A	-1.6347
211	S	A	-1.8646
212	N	A	-2.5271
213	T	A	-2.0504
214	K	A	-2.6588
215	V	A	-1.6499
216	D	A	-2.5564
217	K	A	-2.1884
218	K	A	-2.5424
219	V	A	0.0000
220	E	A	-2.7068
221	P	A	-2.0482
222	K	A	-2.4973
223	S	A	-1.5645