Project name: pasa

Chain sequence(s)	A: RDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQGKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.112
• Maximal score value: 2.2569
• Average score: -0.824
• Total score value: -200.2358

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
40	R	A	-3.0789
41	D	A	-3.4280
42	R	A	-2.8817
43	L	A	-1.8620
44	N	A	-2.4857
45	T	A	-2.2227
46	E	A	0.0000
47	L	A	0.0000
48	D	A	-2.3566
49	R	A	-2.1942
50	L	A	0.0000
51	A	A	-1.2283
52	S	A	-0.8274
53	L	A	0.4303
54	L	A	0.0000
55	P	A	-0.1708
56	F	A	0.0000
57	P	A	-1.2266
58	Q	A	-2.2205
59	D	A	-2.5632
60	V	A	-1.6338
61	I	A	0.0000
62	N	A	-2.9950
63	K	A	-2.9721
64	L	A	-1.8088
65	D	A	-2.0656
66	K	A	-1.3867
67	L	A	-0.2449
68	S	A	-1.0180
69	V	A	0.0000
70	L	A	-0.2010
71	R	A	-1.1949
72	L	A	0.0000
73	S	A	0.0000
74	V	A	0.7946
75	S	A	0.0000
76	Y	A	0.0000
77	L	A	0.8669
78	R	A	-0.9486
79	A	A	0.0000
80	K	A	-0.6082
81	S	A	-0.7017
82	F	A	0.0000
83	F	A	0.0000
84	D	A	-1.2923
85	V	A	0.5809
86	A	A	-0.5379
87	L	A	-0.7366
88	K	A	-2.6222
89	S	A	0.0000
90	S	A	0.0000
91	P	A	-0.7053
92	T	A	-1.4676
93	E	A	0.0000
94	R	A	-3.2106
95	N	A	-3.2194
96	G	A	-2.6230
97	G	A	-2.1745
98	Q	A	-1.8232
99	D	A	-1.2604
100	N	A	-0.6732
101	C	A	-0.3096
102	R	A	-1.5420
103	A	A	-0.9621
104	A	A	-0.9176
105	N	A	-1.6651
106	F	A	-1.9454
107	R	A	-3.1666
108	E	A	-2.8058
109	G	A	0.0000
110	L	A	-1.5215
111	N	A	-1.6917
112	L	A	-0.3069
113	Q	A	-0.1735
114	E	A	-0.6678
115	G	A	0.0000
116	E	A	0.8567
117	F	A	2.2569
118	L	A	2.1195
119	L	A	1.1039
120	Q	A	0.2192
121	A	A	0.1612
122	L	A	0.1386
123	N	A	-1.0120
124	G	A	0.0000
125	F	A	0.0000
126	V	A	0.0000
127	L	A	0.0000
128	V	A	0.0000
129	V	A	0.0000
130	T	A	0.0000
131	T	A	-0.9015
132	D	A	-1.8132
133	A	A	0.0000
134	L	A	-0.4974
135	V	A	0.0000
136	F	A	-0.2505
137	Y	A	0.0000
138	A	A	0.0000
139	S	A	0.0000
140	S	A	-0.3481
141	T	A	0.0000
142	I	A	0.0000
143	Q	A	-0.7114
144	D	A	-1.3941
145	Y	A	0.0000
146	L	A	0.0000
147	G	A	-0.2461
148	F	A	-0.0763
149	Q	A	-0.5529
150	Q	A	0.0000
151	S	A	0.0000
152	D	A	-1.6109
153	V	A	0.0000
154	I	A	0.0000
155	H	A	-1.1551
156	Q	A	-1.5980
157	S	A	-1.2447
158	V	A	0.0000
159	Y	A	-1.1544
160	E	A	-2.2367
161	L	A	0.0000
162	I	A	0.0000
163	H	A	-1.6535
164	T	A	-1.7234
165	E	A	-2.5931
166	D	A	-1.8715
167	R	A	-2.6835
168	A	A	-2.0435
169	E	A	-2.0573
170	F	A	0.0000
171	Q	A	-2.1760
172	R	A	-2.8748
173	Q	A	-1.5182
174	L	A	0.0000
175	H	A	-1.3255
176	W	A	0.0000
177	A	A	0.0000
178	L	A	1.3199
179	N	A	-0.4554
180	P	A	-1.0415
181	S	A	0.0000
182	Q	A	-1.8520
183	C	A	-0.4482
184	T	A	-1.1040
185	E	A	-2.5515
186	S	A	-1.3202
187	G	A	-1.5415
188	Q	A	-2.0144
189	G	A	-1.5729
190	I	A	-1.5367
191	E	A	-2.5712
192	E	A	-1.8282
193	A	A	-0.8943
194	T	A	-0.2619
195	G	A	0.7045
196	L	A	1.2559
197	P	A	0.6378
198	Q	A	-0.6063
199	T	A	0.1140
200	V	A	1.2578
201	V	A	0.5416
202	C	A	0.8131
203	Y	A	-0.1342
204	N	A	-1.4444
205	P	A	-1.8047
206	D	A	-2.6526
207	Q	A	-2.1375
208	I	A	-1.2807
209	P	A	-1.4326
210	P	A	-2.0197
211	E	A	-2.8650
212	N	A	-2.6930
213	S	A	-1.0497
214	P	A	0.0000
215	L	A	-0.2730
216	M	A	0.0000
217	E	A	-2.2007
218	R	A	-1.1235
219	C	A	0.0429
220	F	A	0.0000
221	I	A	1.6450
222	C	A	0.0000
223	R	A	-0.8848
224	L	A	0.0000
225	R	A	-0.5703
226	C	A	0.0000
227	L	A	0.9195
228	L	A	-0.4249
229	D	A	-1.5474
230	N	A	-0.8991
231	S	A	-0.5750
232	S	A	-0.3814
233	G	A	-0.1663
234	F	A	0.0173
235	L	A	0.0000
236	A	A	0.2014
237	M	A	0.0000
238	N	A	0.6592
239	F	A	0.0000
240	Q	A	-0.8152
241	G	A	-1.2104
242	K	A	-1.8675
243	L	A	0.0000
244	K	A	-1.0676
245	Y	A	0.0000
246	L	A	0.0000
247	H	A	-1.5125
248	G	A	-1.6967
249	Q	A	-2.2926
250	K	A	-3.6527
251	K	A	-4.1120
252	K	A	-4.0137
253	G	A	-3.2454
254	K	A	-3.2655
255	D	A	-3.7269
256	G	A	0.0000
257	S	A	-2.3608
258	I	A	-0.4350
259	L	A	-0.9930
260	P	A	0.0000
261	P	A	0.1578
262	Q	A	0.0000
263	L	A	0.0000
264	A	A	0.0000
265	L	A	0.0000
266	F	A	-0.2621
267	A	A	0.0000
268	I	A	-0.0780
269	A	A	0.0000
270	T	A	-0.0451
271	P	A	0.0000
272	L	A	0.5828
273	Q	A	-0.1009
274	P	A	-0.2089
275	P	A	-0.6360
276	S	A	0.0309
277	I	A	0.6339
278	L	A	0.0000
279	E	A	-2.1859
280	I	A	-1.7501
281	R	A	-2.3822
282	T	A	-1.3511