Chain sequence(s) |
A: PTSSEQIMKTGALLLQGFIQDRAEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTGTWQTVTIFVAGVLTASLTIWKKMG B: PTSSEQIMKTGALLLQGFIQDRAGEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTGTWQTVTIFVAGVLTASLTIWKKMG |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
13 | P | A | -0.5801 | |
14 | T | A | -1.0981 | |
15 | S | A | -0.8301 | |
16 | S | A | -1.1561 | |
17 | E | A | -1.2755 | |
18 | Q | A | -1.2870 | |
19 | I | A | 0.0000 | |
20 | M | A | -0.9702 | |
21 | K | A | -0.5238 | |
22 | T | A | 0.0000 | |
23 | G | A | 0.0000 | |
24 | A | A | 0.0000 | |
25 | L | A | 0.0000 | |
26 | L | A | 0.0000 | |
27 | L | A | 0.0000 | |
28 | Q | A | 0.0000 | |
29 | G | A | -1.9104 | |
30 | F | A | -1.6694 | |
31 | I | A | 0.0000 | |
32 | Q | A | -2.6315 | |
33 | D | A | -3.4806 | |
34 | R | A | -3.4122 | |
35 | A | A | -1.8835 | |
41 | E | A | -2.2975 | |
42 | A | A | -1.4826 | |
43 | P | A | -0.9111 | |
44 | E | A | -0.7108 | |
45 | L | A | 0.0000 | |
46 | A | A | -0.6478 | |
47 | L | A | 0.0078 | |
48 | D | A | -0.1817 | |
49 | P | A | -0.6856 | |
50 | V | A | 0.0000 | |
51 | P | A | -1.3383 | |
52 | Q | A | -2.6149 | |
53 | D | A | -2.9304 | |
54 | A | A | -1.9652 | |
55 | S | A | -2.3603 | |
56 | T | A | 0.0000 | |
57 | K | A | -3.4668 | |
58 | K | A | -3.5388 | |
59 | L | A | 0.0000 | |
60 | S | A | -2.8473 | |
61 | E | A | -3.6182 | |
62 | C | A | 0.0000 | |
63 | L | A | 0.0000 | |
64 | K | A | -3.8257 | |
65 | R | A | -3.4130 | |
66 | I | A | 0.0000 | |
67 | G | A | 0.0000 | |
68 | D | A | -3.3099 | |
69 | E | A | -2.1409 | |
70 | L | A | 0.0000 | |
71 | D | A | -1.3848 | |
72 | S | A | -1.2289 | |
73 | N | A | -1.0420 | |
74 | M | A | -0.8999 | |
75 | E | A | -2.2583 | |
76 | L | A | 0.0000 | |
77 | Q | A | -1.5001 | |
78 | R | A | -2.2707 | |
79 | M | A | -1.2858 | |
80 | I | A | 0.0000 | |
81 | A | A | -0.9235 | |
82 | A | A | -1.0681 | |
83 | V | A | 0.0000 | |
84 | D | A | -3.0060 | |
85 | T | A | -1.8173 | |
86 | D | A | -2.7067 | |
87 | S | A | -2.4901 | |
88 | P | A | 0.0000 | |
89 | R | A | -3.2819 | |
90 | E | A | -3.1947 | |
91 | V | A | 0.0000 | |
92 | F | A | 0.0000 | |
93 | F | A | -1.1155 | |
94 | R | A | -2.1607 | |
95 | V | A | 0.0000 | |
96 | A | A | 0.0000 | |
97 | A | A | -1.0439 | |
98 | D | A | -1.0399 | |
99 | M | A | 0.0000 | |
100 | F | A | 0.0000 | |
101 | S | A | -1.5690 | |
102 | D | A | -2.5426 | |
103 | G | A | -2.1487 | |
104 | N | A | -1.9969 | |
105 | F | A | -1.0194 | |
106 | N | A | -0.4760 | |
107 | W | A | 0.0000 | |
108 | G | A | 0.0000 | |
109 | R | A | -0.1095 | |
110 | V | A | 0.0000 | |
111 | V | A | 0.0000 | |
112 | A | A | 0.0000 | |
113 | L | A | 0.0000 | |
114 | F | A | 0.0000 | |
115 | Y | A | 0.0000 | |
116 | F | A | 0.0000 | |
117 | A | A | 0.0000 | |
118 | S | A | 0.0000 | |
119 | K | A | -0.4684 | |
120 | L | A | 0.0000 | |
121 | V | A | 0.0000 | |
122 | L | A | -0.3437 | |
123 | K | A | -0.6189 | |
124 | A | A | 0.0000 | |
125 | L | A | 0.0000 | |
126 | C | A | -0.2150 | |
127 | T | A | -0.7782 | |
128 | K | A | -2.0586 | |
129 | V | A | -1.3329 | |
130 | P | A | -1.4918 | |
131 | E | A | -2.0472 | |
132 | L | A | -1.1412 | |
133 | I | A | -0.3707 | |
134 | R | A | 0.0000 | |
135 | T | A | -0.6813 | |
136 | I | A | 0.0000 | |
137 | M | A | 0.0000 | |
138 | G | A | 0.0000 | |
139 | W | A | 0.0000 | |
140 | T | A | 0.0000 | |
141 | L | A | 0.0000 | |
142 | D | A | -1.9469 | |
143 | F | A | -1.6677 | |
144 | L | A | 0.0000 | |
145 | R | A | -3.4273 | |
146 | E | A | -3.7041 | |
147 | R | A | -3.3145 | |
148 | L | A | 0.0000 | |
149 | L | A | 0.0000 | |
150 | G | A | -2.2084 | |
151 | W | A | -1.6596 | |
152 | I | A | 0.0000 | |
153 | Q | A | -2.2111 | |
154 | D | A | -2.7826 | |
155 | Q | A | -2.5364 | |
156 | G | A | -2.1652 | |
157 | G | A | 0.0000 | |
158 | W | A | 0.0000 | |
159 | D | A | -2.1890 | |
160 | G | A | -1.1331 | |
161 | L | A | 0.0000 | |
162 | L | A | -0.7453 | |
163 | S | A | -0.2927 | |
164 | Y | A | 0.1062 | |
165 | F | A | 0.0000 | |
166 | G | A | -0.5055 | |
167 | T | A | -0.4925 | |
168 | G | A | -0.7943 | |
169 | T | A | -0.6636 | |
170 | W | A | -0.9623 | |
171 | Q | A | -0.6743 | |
172 | T | A | 0.3432 | |
173 | V | A | 0.0000 | |
174 | T | A | 0.0000 | |
175 | I | A | 2.5729 | |
176 | F | A | 2.7626 | |
177 | V | A | 0.0000 | |
178 | A | A | 0.0000 | |
179 | G | A | 1.0088 | |
180 | V | A | 0.9423 | |
181 | L | A | 0.0000 | |
182 | T | A | -0.2456 | |
183 | A | A | 0.0860 | |
184 | S | A | 0.0000 | |
185 | L | A | 0.0000 | |
186 | T | A | -0.4634 | |
187 | I | A | -0.3903 | |
188 | W | A | -1.2279 | |
189 | K | A | -1.9564 | |
190 | K | A | -1.7788 | |
191 | M | A | -0.1562 | |
192 | G | A | -0.8587 | |
13 | P | B | -0.8256 | |
14 | T | B | -1.4474 | |
15 | S | B | -1.3367 | |
16 | S | B | -1.9387 | |
17 | E | B | -2.8669 | |
18 | Q | B | -2.3303 | |
19 | I | B | 0.0000 | |
20 | M | B | -2.0777 | |
21 | K | B | -2.3398 | |
22 | T | B | 0.0000 | |
23 | G | B | 0.0000 | |
24 | A | B | -0.6093 | |
25 | L | B | 0.0000 | |
26 | L | B | 0.0000 | |
27 | L | B | 0.0000 | |
28 | Q | B | -0.7963 | |
29 | G | B | -1.3444 | |
30 | F | B | 0.0000 | |
31 | I | B | 0.0000 | |
32 | Q | B | -1.7711 | |
33 | D | B | -2.1838 | |
34 | R | B | -1.4937 | |
35 | A | B | -0.8251 | |
36 | G | B | -0.8714 | |
41 | E | B | -2.2620 | |
42 | A | B | -1.7154 | |
43 | P | B | -1.3593 | |
44 | E | B | -1.7903 | |
45 | L | B | -1.1190 | |
46 | A | B | -1.0456 | |
47 | L | B | -0.4176 | |
48 | D | B | -1.4628 | |
49 | P | B | -1.1737 | |
50 | V | B | -1.0464 | |
51 | P | B | -1.4703 | |
52 | Q | B | -2.1457 | |
53 | D | B | -2.7158 | |
54 | A | B | -1.8608 | |
55 | S | B | -2.0978 | |
56 | T | B | 0.0000 | |
57 | K | B | -3.3622 | |
58 | K | B | -3.5936 | |
59 | L | B | 0.0000 | |
60 | S | B | -2.5965 | |
61 | E | B | -3.5087 | |
62 | C | B | 0.0000 | |
63 | L | B | 0.0000 | |
64 | K | B | -3.1845 | |
65 | R | B | -3.0736 | |
66 | I | B | 0.0000 | |
67 | G | B | 0.0000 | |
68 | D | B | -2.7682 | |
69 | E | B | -2.0401 | |
70 | L | B | 0.0000 | |
71 | D | B | -1.5531 | |
72 | S | B | -1.0527 | |
73 | N | B | 0.0000 | |
74 | M | B | -0.7872 | |
75 | E | B | -2.1850 | |
76 | L | B | 0.0000 | |
77 | Q | B | -1.4609 | |
78 | R | B | -2.2103 | |
79 | M | B | -1.3815 | |
80 | I | B | 0.0000 | |
81 | A | B | -0.9439 | |
82 | A | B | -1.1202 | |
83 | V | B | 0.0000 | |
84 | D | B | -3.0004 | |
85 | T | B | -1.8027 | |
86 | D | B | -2.6653 | |
87 | S | B | -2.4840 | |
88 | P | B | 0.0000 | |
89 | R | B | -3.1826 | |
90 | E | B | -3.0150 | |
91 | V | B | 0.0000 | |
92 | F | B | 0.0000 | |
93 | F | B | -0.9585 | |
94 | R | B | -1.4232 | |
95 | V | B | 0.0000 | |
96 | A | B | 0.0000 | |
97 | A | B | -0.9168 | |
98 | D | B | -1.1024 | |
99 | M | B | 0.0000 | |
100 | F | B | 0.0000 | |
101 | S | B | -1.5975 | |
102 | D | B | -2.4765 | |
103 | G | B | -1.9834 | |
104 | N | B | -1.6564 | |
105 | F | B | -0.8105 | |
106 | N | B | 0.0000 | |
107 | W | B | 0.0000 | |
108 | G | B | 0.0000 | |
109 | R | B | 0.0000 | |
110 | V | B | 0.0000 | |
111 | V | B | 0.0000 | |
112 | A | B | 0.0000 | |
113 | L | B | 0.0000 | |
114 | F | B | 0.0000 | |
115 | Y | B | 0.0000 | |
116 | F | B | 0.0000 | |
117 | A | B | 0.0000 | |
118 | S | B | 0.0000 | |
119 | K | B | -0.3088 | |
120 | L | B | 0.0000 | |
121 | V | B | 0.0000 | |
122 | L | B | 0.1104 | |
123 | K | B | -0.5134 | |
124 | A | B | 0.0000 | |
125 | L | B | -0.4941 | |
126 | C | B | -0.0200 | |
127 | T | B | -0.6647 | |
128 | K | B | -1.8044 | |
129 | V | B | -1.0730 | |
130 | P | B | -1.3130 | |
131 | E | B | -1.9091 | |
132 | L | B | -1.3508 | |
133 | I | B | -0.6736 | |
134 | R | B | -1.3220 | |
135 | T | B | -1.0698 | |
136 | I | B | 0.0000 | |
137 | M | B | 0.0000 | |
138 | G | B | -0.7704 | |
139 | W | B | -0.9601 | |
140 | T | B | 0.0000 | |
141 | L | B | -1.6608 | |
142 | D | B | -2.8838 | |
143 | F | B | -2.2025 | |
144 | L | B | 0.0000 | |
145 | R | B | -3.8877 | |
146 | E | B | -3.9997 | |
147 | R | B | -3.4636 | |
148 | L | B | 0.0000 | |
149 | L | B | -2.3474 | |
150 | G | B | -2.0442 | |
151 | W | B | -1.4620 | |
152 | I | B | 0.0000 | |
153 | Q | B | -1.9744 | |
154 | D | B | -2.5206 | |
155 | Q | B | -2.0872 | |
156 | G | B | -1.8713 | |
157 | G | B | -1.7195 | |
158 | W | B | 0.0000 | |
159 | D | B | -2.2079 | |
160 | G | B | -1.1930 | |
161 | L | B | 0.0000 | |
162 | L | B | -0.8783 | |
163 | S | B | -0.7934 | |
164 | Y | B | 0.0000 | |
165 | F | B | 0.0000 | |
166 | G | B | -0.5813 | |
167 | T | B | -0.3511 | |
168 | G | B | -0.7343 | |
169 | T | B | 0.0000 | |
170 | W | B | -0.8415 | |
171 | Q | B | -1.1858 | |
172 | T | B | 0.0000 | |
173 | V | B | 0.0000 | |
174 | T | B | 0.0000 | |
175 | I | B | -0.1437 | |
176 | F | B | 0.0000 | |
177 | V | B | 0.0000 | |
178 | A | B | 0.0000 | |
179 | G | B | 0.0000 | |
180 | V | B | 0.0272 | |
181 | L | B | 0.0000 | |
182 | T | B | 0.0000 | |
183 | A | B | -0.0756 | |
184 | S | B | 0.0000 | |
185 | L | B | 0.0000 | |
186 | T | B | -0.6164 | |
187 | I | B | -0.4522 | |
188 | W | B | -1.1847 | |
189 | K | B | -2.2469 | |
190 | K | B | -1.9123 | |
191 | M | B | -0.2798 | |
192 | G | B | -0.8752 |