Chain sequence(s) |
A: PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLAFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLAQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYR B: PQLKPIEASILAARRV |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
11 | P | A | -1.0572 | |
12 | E | A | -1.3344 | |
13 | M | A | -0.2973 | |
14 | V | A | 0.0000 | |
15 | R | A | -1.9640 | |
16 | G | A | -1.3539 | |
17 | Q | A | -1.1749 | |
18 | V | A | -0.4992 | |
19 | F | A | 0.0000 | |
20 | D | A | -1.9895 | |
21 | V | A | 0.0000 | |
22 | G | A | -1.6730 | |
23 | P | A | -0.9820 | |
24 | R | A | -0.8670 | |
25 | Y | A | 0.0000 | |
26 | T | A | -1.5767 | |
27 | N | A | -1.6717 | |
28 | L | A | 0.0000 | |
29 | S | A | -0.1193 | |
30 | Y | A | 0.3930 | |
31 | I | A | 1.0558 | |
32 | G | A | -0.3116 | |
33 | E | A | -1.7158 | |
34 | G | A | -1.2418 | |
35 | A | A | -0.4435 | |
36 | Y | A | -0.4750 | |
37 | G | A | -0.6626 | |
38 | M | A | 0.0000 | |
39 | V | A | 0.1488 | |
40 | C | A | 0.0000 | |
41 | S | A | -0.4387 | |
42 | A | A | 0.0000 | |
43 | Y | A | -1.1050 | |
44 | D | A | 0.0000 | |
45 | N | A | -1.0900 | |
46 | V | A | 0.3821 | |
47 | N | A | -1.3300 | |
48 | K | A | -1.8013 | |
49 | V | A | -0.7487 | |
50 | R | A | -1.9902 | |
51 | V | A | 0.0000 | |
52 | A | A | 0.0000 | |
53 | I | A | 0.0000 | |
54 | K | A | -0.2075 | |
55 | K | A | -0.5811 | |
56 | I | A | -0.2345 | |
57 | S | A | -0.8639 | |
58 | P | A | 0.0000 | |
59 | F | A | -1.7818 | |
60 | E | A | -2.5818 | |
61 | H | A | -1.8795 | |
62 | Q | A | -2.2512 | |
63 | T | A | -1.5580 | |
64 | Y | A | -0.5424 | |
65 | C | A | 0.0000 | |
66 | Q | A | 0.0000 | |
67 | R | A | -1.0538 | |
68 | T | A | 0.0000 | |
69 | L | A | 0.0000 | |
70 | R | A | 0.0000 | |
71 | E | A | 0.0000 | |
72 | I | A | 0.0000 | |
73 | K | A | -0.3576 | |
74 | I | A | 0.0000 | |
75 | L | A | 0.0000 | |
76 | L | A | -0.3681 | |
77 | A | A | -0.4859 | |
78 | F | A | 0.0000 | |
79 | R | A | -2.1658 | |
80 | H | A | 0.0000 | |
81 | E | A | -1.9426 | |
82 | N | A | 0.0000 | |
83 | I | A | 0.0000 | |
84 | I | A | 0.0000 | |
85 | G | A | -1.1401 | |
86 | I | A | -0.7988 | |
87 | N | A | -1.2663 | |
88 | D | A | -0.7302 | |
89 | I | A | 0.0000 | |
90 | I | A | -0.1360 | |
91 | R | A | -0.7564 | |
92 | A | A | -1.2418 | |
93 | P | A | -0.7372 | |
94 | T | A | -0.8758 | |
95 | I | A | -1.6578 | |
96 | E | A | -2.5179 | |
97 | Q | A | -2.5337 | |
98 | M | A | 0.0000 | |
99 | K | A | -2.6620 | |
100 | D | A | -1.4444 | |
101 | V | A | 0.0000 | |
102 | Y | A | 0.0000 | |
103 | I | A | 0.0000 | |
104 | V | A | 0.0000 | |
105 | Q | A | 0.0000 | |
106 | D | A | -1.5450 | |
107 | L | A | -0.8121 | |
108 | M | A | -1.1740 | |
109 | E | A | -1.9159 | |
110 | T | A | -0.9742 | |
111 | D | A | 0.0000 | |
112 | L | A | 0.0000 | |
113 | Y | A | -0.7103 | |
114 | K | A | -1.7080 | |
115 | L | A | 0.0000 | |
116 | L | A | 0.0000 | |
117 | K | A | -2.5902 | |
118 | T | A | -1.6852 | |
119 | Q | A | -1.7646 | |
120 | H | A | -1.6250 | |
121 | L | A | -1.0753 | |
122 | S | A | -1.2705 | |
123 | N | A | -1.9769 | |
124 | D | A | -2.2031 | |
125 | H | A | -1.4239 | |
126 | I | A | 0.0000 | |
127 | C | A | -0.9305 | |
128 | Y | A | 0.0000 | |
129 | F | A | 0.0000 | |
130 | L | A | 0.0000 | |
131 | Y | A | 0.0000 | |
132 | Q | A | 0.0000 | |
133 | I | A | 0.0000 | |
134 | L | A | 0.0000 | |
135 | R | A | 0.0000 | |
136 | G | A | 0.0000 | |
137 | L | A | 0.0000 | |
138 | K | A | 0.0000 | |
139 | Y | A | 0.0000 | |
140 | I | A | 0.0000 | |
141 | H | A | 0.0000 | |
142 | S | A | -0.2138 | |
143 | A | A | 0.0000 | |
144 | N | A | -1.0022 | |
145 | V | A | 0.0000 | |
146 | L | A | 0.0000 | |
147 | H | A | 0.0000 | |
148 | R | A | -0.2636 | |
149 | D | A | -0.2973 | |
150 | L | A | 0.0000 | |
151 | K | A | 0.0000 | |
152 | P | A | 0.0000 | |
153 | S | A | -0.2259 | |
154 | N | A | 0.0000 | |
155 | L | A | 0.0000 | |
156 | L | A | -0.3758 | |
157 | L | A | 0.0000 | |
158 | N | A | -1.2508 | |
159 | T | A | -1.3164 | |
160 | T | A | -0.8482 | |
161 | C | A | 0.0000 | |
162 | D | A | -0.5125 | |
163 | L | A | 0.0000 | |
164 | K | A | -0.7294 | |
165 | I | A | 0.0000 | |
166 | C | A | 0.0000 | |
167 | D | A | -0.8702 | |
168 | F | A | 0.0000 | |
169 | G | A | 0.0000 | |
170 | L | A | -0.4108 | |
171 | A | A | 0.0000 | |
172 | R | A | -0.6346 | |
173 | V | A | -0.7850 | |
174 | A | A | -1.2111 | |
175 | D | A | -2.5352 | |
176 | P | A | -2.4148 | |
177 | D | A | -3.1340 | |
178 | H | A | -2.2384 | |
186 | E | A | -1.6051 | |
187 | Y | A | 0.5154 | |
188 | V | A | 0.5423 | |
189 | A | A | 0.3429 | |
190 | T | A | -0.3912 | |
191 | R | A | -0.8342 | |
192 | W | A | -0.4355 | |
193 | Y | A | 0.0000 | |
194 | R | A | 0.0000 | |
195 | A | A | 0.0000 | |
196 | P | A | 0.0000 | |
197 | E | A | 0.0000 | |
198 | I | A | -0.2997 | |
199 | M | A | 0.0000 | |
200 | L | A | 0.1033 | |
201 | N | A | 0.2152 | |
202 | S | A | -0.7637 | |
203 | K | A | -2.2839 | |
204 | G | A | 0.0000 | |
205 | Y | A | -1.5009 | |
206 | T | A | -1.2600 | |
207 | K | A | -0.6932 | |
208 | S | A | 0.0000 | |
209 | I | A | 0.0000 | |
210 | D | A | 0.0000 | |
211 | I | A | 0.0000 | |
212 | W | A | 0.0000 | |
213 | S | A | 0.0000 | |
214 | V | A | 0.0000 | |
215 | G | A | 0.0000 | |
216 | C | A | 0.0000 | |
217 | I | A | 0.0000 | |
218 | L | A | 0.0000 | |
219 | A | A | 0.0000 | |
220 | E | A | 0.0000 | |
221 | M | A | 0.0000 | |
222 | L | A | -0.5541 | |
223 | S | A | -0.8384 | |
224 | N | A | -1.5596 | |
225 | R | A | -2.0577 | |
226 | P | A | -0.8153 | |
227 | I | A | -0.2348 | |
228 | F | A | 0.0000 | |
229 | P | A | -1.0208 | |
230 | G | A | 0.0000 | |
231 | K | A | -2.0537 | |
232 | H | A | -1.3691 | |
233 | Y | A | -0.1562 | |
234 | L | A | 0.1229 | |
235 | D | A | -0.9138 | |
236 | Q | A | 0.0000 | |
237 | L | A | 0.0000 | |
238 | N | A | -0.8097 | |
239 | H | A | -0.7837 | |
240 | I | A | 0.0000 | |
241 | L | A | 0.0000 | |
242 | G | A | -1.2017 | |
243 | I | A | -0.7606 | |
244 | L | A | 0.0000 | |
245 | G | A | 0.0000 | |
246 | S | A | -1.4618 | |
247 | P | A | -1.2891 | |
248 | S | A | -1.6351 | |
249 | Q | A | -2.5185 | |
250 | E | A | -2.8386 | |
251 | D | A | -2.1172 | |
252 | L | A | 0.0000 | |
253 | N | A | -1.2375 | |
254 | C | A | -0.4428 | |
255 | I | A | 0.4850 | |
256 | I | A | 1.7895 | |
257 | N | A | 0.3842 | |
258 | L | A | 0.3810 | |
259 | K | A | -1.2743 | |
260 | A | A | -0.5595 | |
261 | R | A | -0.6398 | |
262 | N | A | -1.0708 | |
263 | Y | A | -0.1032 | |
264 | L | A | 0.0000 | |
265 | L | A | 0.7426 | |
266 | S | A | 0.1681 | |
267 | L | A | -0.0791 | |
268 | P | A | -0.8086 | |
269 | H | A | -1.8706 | |
270 | K | A | -2.4973 | |
271 | N | A | -2.8133 | |
272 | K | A | -2.5730 | |
273 | V | A | -1.6674 | |
274 | P | A | -1.6183 | |
275 | W | A | 0.0000 | |
276 | N | A | -2.5377 | |
277 | R | A | -2.4758 | |
278 | L | A | -1.0363 | |
279 | F | A | -1.1182 | |
280 | P | A | -1.7936 | |
281 | N | A | -1.9327 | |
282 | A | A | -1.3341 | |
283 | D | A | -1.5603 | |
284 | S | A | -1.5371 | |
285 | K | A | -1.6462 | |
286 | A | A | 0.0000 | |
287 | L | A | 0.0000 | |
288 | D | A | -2.0429 | |
289 | L | A | 0.0000 | |
290 | L | A | 0.0000 | |
291 | D | A | -1.3248 | |
292 | K | A | -1.4925 | |
293 | M | A | 0.0000 | |
294 | L | A | 0.0000 | |
295 | T | A | -0.7622 | |
296 | F | A | -0.5172 | |
297 | N | A | -1.2256 | |
298 | P | A | -1.1506 | |
299 | H | A | -1.8679 | |
300 | K | A | -2.3388 | |
301 | R | A | 0.0000 | |
302 | I | A | -1.3829 | |
303 | E | A | -1.7135 | |
304 | V | A | 0.0000 | |
305 | E | A | -2.4001 | |
306 | Q | A | -2.1636 | |
307 | A | A | 0.0000 | |
308 | L | A | 0.0000 | |
309 | A | A | -1.0023 | |
310 | H | A | 0.0000 | |
311 | P | A | -0.6712 | |
312 | Y | A | 0.0000 | |
313 | L | A | 0.0000 | |
314 | A | A | -0.4858 | |
315 | Q | A | -1.1615 | |
316 | Y | A | 0.0000 | |
317 | Y | A | -0.2331 | |
318 | D | A | -0.6940 | |
319 | P | A | -0.5653 | |
320 | S | A | -0.3600 | |
321 | D | A | -0.5655 | |
322 | E | A | 0.0000 | |
323 | P | A | -0.1053 | |
324 | I | A | 0.9121 | |
325 | A | A | -0.4572 | |
326 | E | A | -1.6180 | |
327 | A | A | -0.9662 | |
328 | P | A | -1.0559 | |
329 | F | A | -1.2928 | |
330 | K | A | -2.2820 | |
331 | F | A | -1.7046 | |
332 | D | A | -2.3383 | |
333 | M | A | -1.8162 | |
334 | E | A | -2.6993 | |
335 | L | A | 0.0000 | |
336 | D | A | -3.4834 | |
337 | D | A | -3.1726 | |
338 | L | A | -2.2950 | |
339 | P | A | -2.2029 | |
340 | K | A | -3.0917 | |
341 | E | A | -3.3962 | |
342 | K | A | -2.8623 | |
343 | L | A | 0.0000 | |
344 | K | A | -2.6053 | |
345 | E | A | -2.8074 | |
346 | L | A | -1.7963 | |
347 | I | A | 0.0000 | |
348 | F | A | -1.4241 | |
349 | E | A | -2.2751 | |
350 | E | A | -1.4158 | |
351 | T | A | 0.0000 | |
352 | A | A | -1.1982 | |
353 | R | A | -1.4123 | |
354 | F | A | -0.3320 | |
355 | Q | A | -0.7628 | |
356 | P | A | -0.7162 | |
357 | G | A | -0.7234 | |
358 | Y | A | -0.4806 | |
359 | R | A | -1.6927 | |
712 | P | B | -1.7397 | |
713 | Q | B | -1.7669 | |
714 | L | B | -1.2804 | |
715 | K | B | -2.1921 | |
716 | P | B | -1.8317 | |
717 | I | B | -1.2641 | |
718 | E | B | -1.7346 | |
719 | A | B | -0.7482 | |
720 | S | B | 0.0000 | |
721 | I | B | 0.9886 | |
722 | L | B | 0.0000 | |
723 | A | B | 0.0000 | |
724 | A | B | -0.1668 | |
725 | R | B | -1.1542 | |
726 | R | B | -0.5395 | |
727 | V | B | 0.8135 |