Project name: 20%_arg_2osl

Chain sequence(s)	A: QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8463
• Maximal score value: 1.7158
• Average score: -0.6622
• Total score value: -288.0718

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.3232
2	I	A	0.0000
3	V	A	0.9501
4	L	A	0.0000
5	S	A	-0.6514
6	Q	A	-0.7397
7	S	A	-0.4774
8	P	A	0.1627
9	A	A	0.3093
10	I	A	1.0988
11	L	A	0.4819
12	S	A	-0.2879
13	A	A	0.0000
14	S	A	-1.8965
15	P	A	-1.9423
16	G	A	-2.3550
17	E	A	-2.9852
18	K	A	-2.9904
19	V	A	-1.3545
20	T	A	-0.3707
21	M	A	0.0000
22	T	A	-0.7135
23	C	A	0.0000
24	R	A	-1.9035
25	A	A	0.0000
26	S	A	-0.3959
27	S	A	-0.5684
28	S	A	-0.6538
29	V	A	0.0000
30	S	A	-0.0613
31	Y	A	0.4957
32	I	A	0.0000
33	H	A	0.0000
34	W	A	0.0000
35	F	A	0.0000
36	Q	A	0.0000
37	Q	A	-0.8800
38	K	A	-1.1114
39	P	A	-0.9549
40	G	A	-0.7294
41	S	A	-0.7079
42	S	A	-0.5312
43	P	A	0.0000
44	K	A	-1.2949
45	P	A	0.0000
46	W	A	-0.4193
47	I	A	0.0000
48	Y	A	0.0506
49	A	A	-0.0756
50	T	A	-0.1658
51	S	A	-0.5998
52	N	A	-0.9994
53	L	A	-0.0080
54	A	A	0.0000
55	S	A	-0.5283
56	G	A	-0.2874
57	V	A	0.0000
58	P	A	0.5858
59	V	A	1.3461
60	R	A	-0.3049
61	F	A	0.0000
62	S	A	-0.1344
63	G	A	-0.4872
64	S	A	-0.5542
65	G	A	-0.6532
66	S	A	-0.6168
67	G	A	-0.6575
68	T	A	-0.9610
69	S	A	-1.1023
70	Y	A	0.0000
71	S	A	-0.6156
72	L	A	0.0000
73	T	A	-0.7288
74	I	A	0.0000
75	S	A	-1.8743
76	R	A	-3.0766
77	V	A	0.0000
78	E	A	-2.4763
79	A	A	0.0000
80	E	A	-2.6929
81	D	A	0.0000
82	A	A	-1.8308
83	A	A	0.0000
84	T	A	-0.6363
85	Y	A	0.0000
86	Y	A	0.0000
87	C	A	0.0000
88	Q	A	0.0000
89	Q	A	0.0000
90	W	A	0.0000
91	T	A	-0.4373
92	S	A	-1.0509
93	N	A	-1.7431
94	P	A	-1.6351
95	P	A	0.0000
96	T	A	0.0000
97	F	A	0.0000
98	G	A	0.0000
99	G	A	-0.9413
100	G	A	-0.5274
101	T	A	0.0000
102	K	A	-0.9827
103	L	A	0.0000
104	E	A	-0.9751
105	I	A	0.0000
106	K	A	-1.5937
107	R	A	-0.9924
108	T	A	-0.1332
109	V	A	0.4076
110	A	A	0.1042
111	A	A	-0.1614
112	P	A	0.0000
113	S	A	-0.1655
114	V	A	0.0000
115	F	A	0.0480
116	I	A	0.0000
117	F	A	0.0000
118	P	A	-0.6393
119	P	A	-0.6742
120	S	A	-1.3715
121	D	A	-2.4187
122	E	A	-1.9868
123	Q	A	0.0000
124	L	A	-1.3868
125	K	A	-1.7233
126	S	A	-1.2867
127	G	A	-1.0635
128	T	A	-0.9117
129	A	A	0.0000
130	S	A	0.0000
131	V	A	0.0000
132	V	A	0.0000
133	C	A	0.0000
134	L	A	0.0000
135	L	A	0.0000
136	N	A	0.0000
137	N	A	-0.6381
138	F	A	0.0000
139	Y	A	0.0000
140	P	A	-1.7035
141	R	A	-3.0273
142	E	A	-3.2839
143	A	A	-2.4350
144	K	A	-2.4501
145	V	A	0.0000
146	Q	A	-0.5888
147	W	A	0.0000
148	K	A	-0.5452
149	V	A	0.0000
150	D	A	-1.8269
151	N	A	-1.4304
152	A	A	-0.1273
153	L	A	0.7938
154	Q	A	0.0366
155	S	A	-0.3036
156	G	A	-0.9185
157	N	A	-0.7353
158	S	A	-1.0214
159	Q	A	-1.8482
160	E	A	-2.2313
161	S	A	-1.1690
162	V	A	-0.9933
163	T	A	-1.0353
164	E	A	-2.1253
165	Q	A	-2.0790
166	D	A	-2.1655
167	S	A	-2.4370
168	K	A	-2.7700
169	D	A	-1.8514
170	S	A	0.0000
171	T	A	0.0000
172	Y	A	-1.1183
173	S	A	0.0000
174	L	A	0.0000
175	S	A	0.0000
176	S	A	0.0000
177	T	A	-0.2283
178	L	A	0.7524
179	T	A	0.2951
180	L	A	-0.4122
181	S	A	-1.1891
182	K	A	-2.1237
183	A	A	-1.8118
184	D	A	-2.7232
185	Y	A	0.0000
186	E	A	-3.8463
187	K	A	-3.7680
188	H	A	-3.2035
189	K	A	-3.7101
190	V	A	0.0000
191	Y	A	0.0000
192	A	A	0.0000
193	C	A	0.0000
194	E	A	-0.9126
195	V	A	0.0000
196	T	A	-1.2788
197	H	A	-1.6344
198	Q	A	-1.7917
199	G	A	-0.4805
200	L	A	-0.2864
201	S	A	-0.4908
202	S	A	-0.4749
203	P	A	-0.6340
204	V	A	-0.0590
205	T	A	-0.3861
206	K	A	-0.4806
207	S	A	-0.6430
208	F	A	0.0000
209	N	A	-2.7088
210	R	A	-3.1821
211	G	A	-2.6447
212	E	A	-2.7636
1	Q	A	-1.0693
2	V	A	-0.1145
3	Q	A	-0.9974
4	L	A	0.0000
5	Q	A	-1.7940
6	Q	A	-1.0823
7	P	A	-0.9121
8	G	A	-0.8804
9	A	A	-0.8352
10	E	A	-1.0062
11	L	A	-0.4051
12	V	A	0.0000
13	K	A	-1.8815
14	P	A	-1.1470
15	G	A	-1.1165
16	A	A	-0.9525
17	S	A	-1.1665
18	V	A	0.0000
19	K	A	-1.7868
20	M	A	0.0000
21	S	A	-0.8423
22	C	A	0.0000
23	K	A	-1.5162
24	A	A	0.0000
25	S	A	-0.8516
26	G	A	-0.5682
27	Y	A	-0.0753
28	T	A	-0.1532
29	F	A	0.0000
30	T	A	-0.6586
31	S	A	-0.1278
32	Y	A	0.4471
33	N	A	-0.1548
34	M	A	0.0000
35	H	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	K	A	-0.6415
39	Q	A	-0.7610
40	T	A	0.0000
41	P	A	-1.0847
42	G	A	-1.5516
43	R	A	-2.4016
44	G	A	0.0000
45	L	A	0.0000
46	E	A	-1.3057
47	W	A	0.0000
48	I	A	0.0000
49	G	A	0.0000
50	A	A	0.0000
51	I	A	0.0000
52	Y	A	-0.6732
53	P	A	0.0000
54	G	A	-1.3306
55	N	A	-2.0498
56	G	A	-1.9403
57	D	A	-2.3768
58	T	A	-1.1086
59	S	A	-0.8129
60	Y	A	-1.0341
61	N	A	-2.0551
62	Q	A	-2.9071
63	K	A	-2.9312
64	F	A	0.0000
65	K	A	-2.7488
66	G	A	-1.9135
67	K	A	-1.6765
68	A	A	0.0000
69	T	A	-0.9151
70	L	A	0.0000
71	T	A	-0.5723
72	A	A	-0.8210
73	D	A	-1.7028
74	K	A	-2.2146
75	S	A	-1.3304
76	S	A	-1.1818
77	S	A	-1.3088
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.5206
81	M	A	0.0000
82	Q	A	-1.4601
83	L	A	0.0000
84	S	A	-0.9434
85	S	A	-0.9662
86	L	A	0.0000
87	T	A	-1.1866
88	S	A	-1.3420
89	E	A	-1.9315
90	D	A	0.0000
91	S	A	-0.6360
92	A	A	0.0000
93	V	A	0.0376
94	Y	A	0.0000
95	Y	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	S	A	0.0000
100	T	A	0.0000
101	Y	A	1.7158
102	Y	A	1.5945
103	G	A	0.3832
104	G	A	0.2566
105	D	A	0.4663
106	W	A	0.9425
107	Y	A	0.6307
108	F	A	0.0000
109	N	A	-0.2858
110	V	A	-0.1135
111	W	A	-0.3199
112	G	A	0.0000
113	A	A	-0.4770
114	G	A	-0.3988
115	T	A	0.0000
116	T	A	-0.3635
117	V	A	0.0000
118	T	A	-0.5387
119	V	A	-0.7244
120	S	A	-0.5390
121	A	A	-0.5656
122	A	A	-0.3784
123	S	A	-0.5139
124	T	A	-0.7892
125	K	A	-1.0819
126	G	A	-1.2745
127	P	A	-0.5645
128	S	A	-0.4215
129	V	A	0.0000
130	F	A	0.0000
131	P	A	-1.0727
132	L	A	0.0000
133	A	A	-1.0744
134	P	A	0.0000
135	S	A	-1.2641
136	S	A	-1.2100
137	K	A	-1.3249
138	S	A	-0.8254
139	T	A	-0.7819
140	S	A	-0.8617
141	G	A	-1.0506
142	G	A	-0.9042
143	T	A	-0.6654
144	A	A	-0.4567
145	A	A	0.0000
146	L	A	0.0000
147	G	A	0.0000
148	C	A	0.0000
149	L	A	0.0000
150	V	A	0.0000
151	K	A	-0.0879
152	D	A	-0.4653
153	Y	A	0.0000
154	F	A	-0.1881
155	P	A	0.0000
156	E	A	-0.9379
157	P	A	-0.8046
158	V	A	-0.3348
159	T	A	-0.4110
160	V	A	0.3386
161	S	A	-0.0804
162	W	A	0.0000
163	N	A	-0.8072
164	S	A	-0.6712
165	G	A	-0.4347
166	A	A	-0.2312
167	L	A	-0.0325
168	T	A	-0.1790
169	S	A	-0.1863
170	G	A	-0.2223
171	V	A	0.1690
172	H	A	-0.3442
173	T	A	-0.1503
174	F	A	0.0000
175	P	A	-0.5422
176	A	A	0.3034
177	V	A	0.4983
178	L	A	1.3665
179	Q	A	0.1405
180	S	A	-0.0864
181	S	A	-0.2543
182	G	A	-0.0155
183	L	A	0.1769
184	Y	A	0.4641
185	S	A	0.2753
186	L	A	0.2995
187	S	A	0.0000
188	S	A	0.0000
189	V	A	0.0000
190	V	A	0.0000
191	T	A	-0.1358
192	V	A	0.0000
193	P	A	-0.5446
194	S	A	-0.6951
195	S	A	-0.6095
196	S	A	-0.5879
197	L	A	-0.7794
198	G	A	-0.6951
199	T	A	-0.7309
200	Q	A	-1.1001
201	T	A	-1.1245
202	Y	A	0.0000
203	I	A	-1.2787
204	C	A	0.0000
205	N	A	-1.5372
206	V	A	0.0000
207	N	A	-1.6089
208	H	A	0.0000
209	K	A	-2.6904
210	P	A	-1.5869
211	S	A	-1.7813
212	N	A	-2.5358
213	T	A	-2.0216
214	K	A	-2.6646
215	V	A	-1.6656
216	D	A	-2.6317
217	K	A	-2.3095
218	K	A	-2.6691
219	V	A	0.0000
220	E	A	-2.6276
221	P	A	-1.9060
222	K	A	-2.0595
223	S	A	-1.2814