Project name: 46b63d57f5e351f
Status: done
submitted: 2018-03-18 12:18:49, status changed: 2018-03-18 13:26:36
Settings
Chain sequence(s)
|
A: GIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKGDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATC
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.5425
-
Maximal score value
-
0.897
-
Average score
-
-1.1846
-
Total score value
-
-258.2458
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
15 |
G |
A |
-0.7575 |
|
16 |
I |
A |
0.0000 |
|
17 |
R |
A |
-0.9401 |
|
18 |
A |
A |
0.0000 |
|
19 |
V |
A |
0.0000 |
|
20 |
L |
A |
0.0000 |
|
21 |
L |
A |
0.0000 |
|
22 |
G |
A |
0.0000 |
|
23 |
P |
A |
0.0000 |
|
24 |
P |
A |
-0.6697 |
|
25 |
G |
A |
-0.3971 |
|
26 |
A |
A |
0.0000 |
|
27 |
G |
A |
-0.5151 |
|
28 |
K |
A |
-0.7336 |
|
29 |
G |
A |
-1.0049 |
|
30 |
T |
A |
-0.8352 |
|
31 |
Q |
A |
0.0000 |
|
32 |
A |
A |
0.0000 |
|
33 |
P |
A |
-1.9024 |
|
34 |
R |
A |
-2.7700 |
|
35 |
L |
A |
0.0000 |
|
36 |
A |
A |
-1.7430 |
|
37 |
E |
A |
-2.7378 |
|
38 |
N |
A |
-2.2303 |
|
39 |
F |
A |
-0.8557 |
|
40 |
C |
A |
-0.4861 |
|
41 |
V |
A |
0.0000 |
|
42 |
C |
A |
0.0000 |
|
43 |
H |
A |
-0.8303 |
|
44 |
L |
A |
0.0000 |
|
45 |
A |
A |
-0.9141 |
|
46 |
T |
A |
-1.0068 |
|
47 |
G |
A |
-1.5436 |
|
48 |
D |
A |
-2.4299 |
|
49 |
M |
A |
0.0000 |
|
50 |
L |
A |
-1.2725 |
|
51 |
R |
A |
-2.3902 |
|
52 |
A |
A |
-1.2117 |
|
53 |
M |
A |
-1.4788 |
|
54 |
V |
A |
-1.6184 |
|
55 |
A |
A |
-0.7517 |
|
56 |
S |
A |
-0.8737 |
|
57 |
G |
A |
-1.4422 |
|
58 |
S |
A |
-1.7012 |
|
59 |
E |
A |
-2.9324 |
|
60 |
L |
A |
0.0000 |
|
61 |
G |
A |
0.0000 |
|
62 |
K |
A |
-3.2979 |
|
63 |
K |
A |
-2.7882 |
|
64 |
L |
A |
0.0000 |
|
65 |
K |
A |
-2.8223 |
|
66 |
A |
A |
-2.0399 |
|
67 |
T |
A |
-1.4797 |
|
68 |
M |
A |
-1.2577 |
|
69 |
D |
A |
-2.1478 |
|
70 |
A |
A |
-1.3526 |
|
71 |
G |
A |
-1.4459 |
|
72 |
K |
A |
-1.4210 |
|
73 |
L |
A |
0.5796 |
|
74 |
V |
A |
-0.0109 |
|
75 |
S |
A |
-0.5726 |
|
76 |
D |
A |
-1.3931 |
|
77 |
E |
A |
-2.0759 |
|
78 |
M |
A |
0.0000 |
|
79 |
V |
A |
-0.8345 |
|
80 |
V |
A |
-1.5519 |
|
81 |
E |
A |
-2.0935 |
|
82 |
L |
A |
0.0000 |
|
83 |
I |
A |
0.0000 |
|
84 |
E |
A |
-2.2702 |
|
85 |
K |
A |
-2.2725 |
|
86 |
N |
A |
-1.6253 |
|
87 |
L |
A |
0.0000 |
|
88 |
E |
A |
-2.6187 |
|
89 |
T |
A |
-1.2675 |
|
90 |
P |
A |
-0.6125 |
|
91 |
L |
A |
0.6354 |
|
92 |
C |
A |
0.0000 |
|
93 |
K |
A |
-1.8715 |
|
94 |
N |
A |
-0.9341 |
|
95 |
G |
A |
0.0000 |
|
96 |
F |
A |
0.0000 |
|
97 |
L |
A |
0.0000 |
|
98 |
L |
A |
0.0000 |
|
99 |
D |
A |
-0.7912 |
|
100 |
G |
A |
-1.0046 |
|
101 |
F |
A |
0.0000 |
|
102 |
P |
A |
0.0000 |
|
103 |
R |
A |
-2.2049 |
|
104 |
T |
A |
-1.5383 |
|
105 |
V |
A |
-1.3900 |
|
106 |
R |
A |
-2.3984 |
|
107 |
Q |
A |
-2.1592 |
|
108 |
A |
A |
0.0000 |
|
109 |
E |
A |
-2.3592 |
|
110 |
M |
A |
-2.1503 |
|
111 |
L |
A |
0.0000 |
|
112 |
D |
A |
-2.8626 |
|
113 |
D |
A |
-3.7414 |
|
114 |
L |
A |
0.0000 |
|
115 |
M |
A |
0.0000 |
|
116 |
E |
A |
-4.5425 |
|
117 |
K |
A |
-4.0558 |
|
118 |
R |
A |
-3.5772 |
|
119 |
K |
A |
-3.8486 |
|
120 |
E |
A |
-3.2644 |
|
121 |
K |
A |
-3.2280 |
|
122 |
L |
A |
0.0000 |
|
123 |
D |
A |
-1.0542 |
|
124 |
S |
A |
0.0000 |
|
125 |
V |
A |
0.0000 |
|
126 |
I |
A |
0.0000 |
|
127 |
E |
A |
-0.4124 |
|
128 |
F |
A |
0.0000 |
|
129 |
S |
A |
-0.6243 |
|
130 |
I |
A |
-0.5545 |
|
131 |
P |
A |
-0.5364 |
|
132 |
D |
A |
-1.1538 |
|
133 |
S |
A |
-0.9168 |
|
134 |
L |
A |
-0.6097 |
|
135 |
L |
A |
0.0000 |
|
136 |
I |
A |
0.0000 |
|
137 |
R |
A |
-2.3532 |
|
138 |
R |
A |
-1.6909 |
|
139 |
I |
A |
-1.4311 |
|
140 |
T |
A |
-2.7010 |
|
141 |
G |
A |
-2.7536 |
|
142 |
R |
A |
-2.6574 |
|
143 |
L |
A |
0.0000 |
|
144 |
I |
A |
0.0000 |
|
145 |
H |
A |
0.0000 |
|
146 |
P |
A |
-1.6476 |
|
147 |
K |
A |
-2.3102 |
|
148 |
S |
A |
-1.4548 |
|
149 |
G |
A |
-1.7957 |
|
150 |
R |
A |
-1.8080 |
|
151 |
S |
A |
-1.4102 |
|
152 |
Y |
A |
0.0000 |
|
153 |
H |
A |
0.0000 |
|
154 |
E |
A |
-3.2858 |
|
155 |
E |
A |
-3.1631 |
|
156 |
F |
A |
-1.8225 |
|
157 |
N |
A |
-2.0901 |
|
158 |
P |
A |
-2.8066 |
|
159 |
P |
A |
0.0000 |
|
160 |
K |
A |
-3.1338 |
|
161 |
E |
A |
-3.1771 |
|
162 |
P |
A |
-2.1229 |
|
163 |
M |
A |
-1.5846 |
|
164 |
K |
A |
-2.0843 |
|
165 |
G |
A |
0.0000 |
|
166 |
D |
A |
-1.3022 |
|
167 |
I |
A |
0.8970 |
|
168 |
T |
A |
-0.0287 |
|
169 |
G |
A |
-1.4207 |
|
170 |
E |
A |
-1.6751 |
|
171 |
P |
A |
-1.3041 |
|
172 |
L |
A |
0.0000 |
|
173 |
I |
A |
-0.1716 |
|
174 |
R |
A |
-2.4402 |
|
175 |
R |
A |
-3.2562 |
|
176 |
S |
A |
-2.5339 |
|
177 |
D |
A |
-3.5537 |
|
178 |
D |
A |
-3.6294 |
|
179 |
N |
A |
-3.6307 |
|
180 |
E |
A |
-3.8745 |
|
181 |
K |
A |
-3.0588 |
|
182 |
A |
A |
-2.0685 |
|
183 |
L |
A |
0.0000 |
|
184 |
K |
A |
-2.0553 |
|
185 |
I |
A |
-0.3376 |
|
186 |
R |
A |
-1.9835 |
|
187 |
L |
A |
0.0000 |
|
188 |
Q |
A |
-1.5403 |
|
189 |
A |
A |
-0.9847 |
|
190 |
Y |
A |
-1.1356 |
|
191 |
H |
A |
-1.2031 |
|
192 |
T |
A |
-0.9069 |
|
193 |
Q |
A |
-0.9200 |
|
194 |
T |
A |
0.0000 |
|
195 |
T |
A |
-0.5729 |
|
196 |
P |
A |
-1.0430 |
|
197 |
L |
A |
0.0000 |
|
198 |
I |
A |
-1.3555 |
|
199 |
E |
A |
-2.8509 |
|
200 |
Y |
A |
-2.2551 |
|
201 |
Y |
A |
0.0000 |
|
202 |
R |
A |
-3.5544 |
|
203 |
K |
A |
-3.3684 |
|
204 |
R |
A |
-2.3618 |
|
205 |
G |
A |
-2.0089 |
|
206 |
I |
A |
-1.1730 |
|
207 |
H |
A |
-1.3738 |
|
208 |
S |
A |
-0.7424 |
|
209 |
A |
A |
-0.3688 |
|
210 |
I |
A |
0.0000 |
|
211 |
D |
A |
-1.3656 |
|
212 |
A |
A |
0.0000 |
|
213 |
S |
A |
-0.6234 |
|
214 |
Q |
A |
-0.9726 |
|
215 |
T |
A |
-0.8069 |
|
216 |
P |
A |
-0.9859 |
|
217 |
D |
A |
-1.3348 |
|
218 |
V |
A |
0.1491 |
|
219 |
V |
A |
0.0000 |
|
220 |
F |
A |
0.0000 |
|
221 |
A |
A |
0.1878 |
|
222 |
S |
A |
-0.0728 |
|
223 |
I |
A |
0.0000 |
|
224 |
L |
A |
0.2492 |
|
225 |
A |
A |
-0.2519 |
|
226 |
A |
A |
0.0000 |
|
227 |
F |
A |
0.0000 |
|
228 |
S |
A |
-0.7239 |
|
229 |
K |
A |
-1.4893 |
|
230 |
A |
A |
-0.6866 |
|
231 |
T |
A |
-0.3776 |
|
232 |
C |
A |
0.0885 |
|