Project name: 5wkz:L
Status: done
submitted: 2019-03-21 13:07:50, status changed: 2019-03-21 13:16:59
Settings
Chain sequence(s)
|
L: VLTQPPSVSAAPGQKVVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAYVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.1821
-
Maximal score value
-
2.5792
-
Average score
-
-0.6877
-
Total score value
-
-145.7997
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
V |
L |
1.8241 |
|
2 |
L |
L |
0.0000 |
|
3 |
T |
L |
0.2367 |
|
4 |
Q |
L |
0.0000 |
|
5 |
P |
L |
-0.4329 |
|
6 |
P |
L |
-0.6643 |
|
7 |
S |
L |
-0.5507 |
|
8 |
V |
L |
-0.1336 |
|
9 |
S |
L |
-0.0723 |
|
10 |
A |
L |
0.0000 |
|
11 |
A |
L |
-0.8175 |
|
12 |
P |
L |
-1.3438 |
|
13 |
G |
L |
-1.7517 |
|
14 |
Q |
L |
-2.3001 |
|
15 |
K |
L |
-2.4433 |
|
16 |
V |
L |
0.0000 |
|
17 |
T |
L |
-0.4815 |
|
18 |
I |
L |
0.0000 |
|
19 |
S |
L |
-0.3495 |
|
20 |
C |
L |
0.0000 |
|
21 |
S |
L |
-0.2202 |
|
22 |
G |
L |
0.0137 |
|
23 |
S |
L |
-0.4940 |
|
24 |
S |
L |
-0.9665 |
|
25 |
S |
L |
-0.6428 |
|
26 |
N |
L |
0.0000 |
|
27 |
I |
L |
0.0000 |
|
28 |
G |
L |
-1.1415 |
|
29 |
N |
L |
-1.2362 |
|
30 |
N |
L |
-0.1294 |
|
31 |
Y |
L |
0.7772 |
|
32 |
V |
L |
0.0000 |
|
33 |
S |
L |
0.2427 |
|
34 |
W |
L |
0.0000 |
|
35 |
Y |
L |
0.1507 |
|
36 |
Q |
L |
0.0000 |
|
37 |
Q |
L |
-0.6634 |
|
38 |
L |
L |
-0.3485 |
|
39 |
P |
L |
-0.7023 |
|
40 |
G |
L |
-0.5325 |
|
41 |
T |
L |
-0.4375 |
|
42 |
A |
L |
-0.3711 |
|
43 |
P |
L |
-0.6733 |
|
44 |
K |
L |
-0.8326 |
|
45 |
L |
L |
0.0623 |
|
46 |
L |
L |
0.0000 |
|
47 |
I |
L |
0.0000 |
|
48 |
Y |
L |
-0.4967 |
|
49 |
D |
L |
-0.9142 |
|
50 |
N |
L |
-1.2238 |
|
51 |
N |
L |
-2.2602 |
|
52 |
K |
L |
-2.5978 |
|
53 |
R |
L |
-2.0756 |
|
54 |
P |
L |
-0.7148 |
|
55 |
S |
L |
-0.7549 |
|
56 |
G |
L |
-0.8693 |
|
57 |
I |
L |
-0.9358 |
|
58 |
P |
L |
-1.3483 |
|
59 |
D |
L |
-2.3722 |
|
60 |
R |
L |
-1.5768 |
|
61 |
F |
L |
0.0000 |
|
62 |
S |
L |
-1.4642 |
|
63 |
G |
L |
-1.3271 |
|
64 |
S |
L |
-1.2649 |
|
65 |
K |
L |
-1.0433 |
|
66 |
S |
L |
-0.8072 |
|
67 |
G |
L |
-1.0471 |
|
68 |
T |
L |
-0.9474 |
|
69 |
S |
L |
-0.6878 |
|
70 |
A |
L |
0.0000 |
|
71 |
T |
L |
-0.5852 |
|
72 |
L |
L |
0.0000 |
|
73 |
G |
L |
-0.7998 |
|
74 |
I |
L |
0.0000 |
|
75 |
T |
L |
-1.7853 |
|
76 |
G |
L |
-1.5430 |
|
77 |
L |
L |
0.0000 |
|
78 |
Q |
L |
-1.6038 |
|
79 |
T |
L |
-0.9749 |
|
80 |
G |
L |
-0.9182 |
|
81 |
D |
L |
0.0000 |
|
82 |
E |
L |
-0.8220 |
|
83 |
A |
L |
0.0000 |
|
84 |
D |
L |
-0.8824 |
|
85 |
Y |
L |
0.0000 |
|
86 |
Y |
L |
0.0422 |
|
87 |
C |
L |
0.0000 |
|
88 |
G |
L |
0.0000 |
|
89 |
T |
L |
0.0000 |
|
90 |
W |
L |
2.0577 |
|
91 |
D |
L |
0.0000 |
|
92 |
S |
L |
0.4370 |
|
93 |
S |
L |
0.7570 |
|
94 |
L |
L |
1.4510 |
|
95 |
S |
L |
0.6637 |
|
96 |
A |
L |
1.2239 |
|
97 |
Y |
L |
2.0168 |
|
98 |
V |
L |
2.5792 |
|
99 |
V |
L |
0.0000 |
|
100 |
F |
L |
1.8606 |
|
101 |
G |
L |
0.0000 |
|
102 |
G |
L |
-0.1045 |
|
103 |
G |
L |
-0.4536 |
|
104 |
T |
L |
0.0000 |
|
105 |
K |
L |
-0.9778 |
|
106 |
L |
L |
0.0000 |
|
107 |
T |
L |
-0.2458 |
|
108 |
V |
L |
0.0000 |
|
109 |
L |
L |
-0.0402 |
|
110 |
G |
L |
-0.6923 |
|
111 |
Q |
L |
-1.1607 |
|
112 |
P |
L |
-1.3252 |
|
113 |
K |
L |
-2.2318 |
|
114 |
A |
L |
-1.3724 |
|
115 |
A |
L |
-0.8200 |
|
116 |
P |
L |
0.0000 |
|
117 |
S |
L |
-0.4222 |
|
118 |
V |
L |
0.0000 |
|
119 |
T |
L |
0.1015 |
|
120 |
L |
L |
0.0000 |
|
121 |
F |
L |
1.7498 |
|
122 |
P |
L |
0.7083 |
|
123 |
P |
L |
0.0000 |
|
124 |
S |
L |
-1.0801 |
|
125 |
S |
L |
-1.8680 |
|
126 |
E |
L |
-2.8605 |
|
127 |
E |
L |
-2.4880 |
|
128 |
L |
L |
-2.4475 |
|
129 |
Q |
L |
-2.6585 |
|
130 |
A |
L |
-2.2343 |
|
131 |
N |
L |
-2.9628 |
|
132 |
K |
L |
-3.0817 |
|
133 |
A |
L |
0.0000 |
|
134 |
T |
L |
-0.1196 |
|
135 |
L |
L |
0.0000 |
|
136 |
V |
L |
1.1321 |
|
137 |
C |
L |
0.0000 |
|
138 |
L |
L |
0.8689 |
|
139 |
I |
L |
0.0000 |
|
140 |
S |
L |
-0.5911 |
|
141 |
D |
L |
-1.5091 |
|
142 |
F |
L |
0.0000 |
|
143 |
Y |
L |
0.0000 |
|
144 |
P |
L |
-0.9664 |
|
145 |
G |
L |
-0.9550 |
|
146 |
A |
L |
-0.2443 |
|
147 |
V |
L |
-0.2331 |
|
148 |
T |
L |
-0.2438 |
|
149 |
V |
L |
0.0000 |
|
150 |
A |
L |
-0.6225 |
|
151 |
W |
L |
0.0000 |
|
152 |
K |
L |
-0.9817 |
|
153 |
A |
L |
-1.2498 |
|
154 |
D |
L |
-1.4266 |
|
155 |
S |
L |
-0.9605 |
|
156 |
S |
L |
-0.7876 |
|
157 |
P |
L |
-0.8873 |
|
158 |
V |
L |
-0.9072 |
|
159 |
K |
L |
-1.8859 |
|
160 |
A |
L |
-1.0615 |
|
161 |
G |
L |
-0.9573 |
|
162 |
V |
L |
-1.0276 |
|
163 |
E |
L |
-1.8188 |
|
164 |
T |
L |
-0.7659 |
|
165 |
T |
L |
-0.4952 |
|
166 |
T |
L |
-0.3335 |
|
167 |
P |
L |
-0.6380 |
|
168 |
S |
L |
-1.3291 |
|
169 |
K |
L |
-2.5735 |
|
170 |
Q |
L |
-2.0518 |
|
171 |
S |
L |
-1.6849 |
|
172 |
N |
L |
-2.2591 |
|
173 |
N |
L |
-2.3384 |
|
174 |
K |
L |
-2.2770 |
|
175 |
Y |
L |
-1.4908 |
|
176 |
A |
L |
-0.7636 |
|
177 |
A |
L |
0.0000 |
|
178 |
S |
L |
-0.0191 |
|
179 |
S |
L |
0.0000 |
|
180 |
Y |
L |
0.2784 |
|
181 |
L |
L |
0.0000 |
|
182 |
S |
L |
-0.6626 |
|
183 |
L |
L |
-1.1418 |
|
184 |
T |
L |
-1.8652 |
|
185 |
P |
L |
-2.5842 |
|
186 |
E |
L |
-3.1821 |
|
187 |
Q |
L |
-2.2902 |
|
188 |
W |
L |
0.0000 |
|
189 |
K |
L |
-3.0882 |
|
190 |
S |
L |
-2.3900 |
|
191 |
H |
L |
-2.4172 |
|
192 |
R |
L |
-2.5244 |
|
193 |
S |
L |
-1.5384 |
|
194 |
Y |
L |
0.0000 |
|
195 |
S |
L |
-1.0334 |
|
196 |
C |
L |
0.0000 |
|
197 |
Q |
L |
-1.1499 |
|
198 |
V |
L |
0.0000 |
|
199 |
T |
L |
-0.8078 |
|
200 |
H |
L |
0.0000 |
|
201 |
E |
L |
-2.3045 |
|
202 |
G |
L |
-1.4545 |
|
203 |
S |
L |
-0.9070 |
|
204 |
T |
L |
-0.8363 |
|
205 |
V |
L |
-0.8521 |
|
206 |
E |
L |
-2.2199 |
|
207 |
K |
L |
-1.5704 |
|
208 |
T |
L |
-0.7843 |
|
209 |
V |
L |
-0.0414 |
|
210 |
A |
L |
-0.6642 |
|
211 |
P |
L |
-1.0136 |
|
212 |
T |
L |
-0.3501 |
|