Project name: 5i76:A
Status: done
submitted: 2019-03-21 15:00:10, status changed: 2019-03-21 15:11:54
Settings
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5405
-
Maximal score value
-
1.9432
-
Average score
-
-0.7766
-
Total score value
-
-165.426
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
A |
-1.4600 |
|
2 |
I |
A |
0.0000 |
|
3 |
L |
A |
0.7845 |
|
4 |
L |
A |
0.0000 |
|
5 |
T |
A |
0.0164 |
|
6 |
Q |
A |
0.0000 |
|
7 |
S |
A |
0.1511 |
|
8 |
P |
A |
0.8210 |
|
9 |
V |
A |
1.9432 |
|
10 |
I |
A |
1.5032 |
|
11 |
L |
A |
0.6402 |
|
12 |
S |
A |
-0.1740 |
|
13 |
V |
A |
0.0000 |
|
14 |
S |
A |
-1.7344 |
|
15 |
P |
A |
-1.9232 |
|
16 |
G |
A |
-2.2484 |
|
17 |
E |
A |
-3.1221 |
|
18 |
R |
A |
-3.2838 |
|
19 |
V |
A |
0.0000 |
|
20 |
S |
A |
-0.8453 |
|
21 |
F |
A |
0.0000 |
|
22 |
S |
A |
-0.8240 |
|
23 |
C |
A |
0.0000 |
|
24 |
R |
A |
-2.5189 |
|
25 |
A |
A |
0.0000 |
|
26 |
S |
A |
-1.0242 |
|
27 |
Q |
A |
-1.9303 |
|
28 |
S |
A |
-1.6938 |
|
29 |
I |
A |
0.0000 |
|
30 |
G |
A |
-1.0228 |
|
31 |
T |
A |
-0.7026 |
|
32 |
N |
A |
-0.8118 |
|
33 |
I |
A |
0.0000 |
|
34 |
H |
A |
0.0000 |
|
35 |
W |
A |
0.0000 |
|
36 |
Y |
A |
-0.0671 |
|
37 |
Q |
A |
0.0000 |
|
38 |
Q |
A |
-1.4290 |
|
39 |
R |
A |
-2.2740 |
|
40 |
T |
A |
-1.9546 |
|
41 |
N |
A |
-1.9838 |
|
42 |
G |
A |
-1.5397 |
|
43 |
S |
A |
-1.0916 |
|
44 |
P |
A |
-0.9739 |
|
45 |
R |
A |
-0.7198 |
|
46 |
L |
A |
-0.0517 |
|
47 |
L |
A |
0.0000 |
|
48 |
I |
A |
0.0000 |
|
49 |
K |
A |
-0.8226 |
|
50 |
Y |
A |
-0.3226 |
|
51 |
A |
A |
0.0000 |
|
52 |
S |
A |
-1.1796 |
|
53 |
E |
A |
-1.9398 |
|
54 |
S |
A |
-1.1162 |
|
55 |
I |
A |
-0.4887 |
|
56 |
S |
A |
-0.2540 |
|
57 |
G |
A |
-0.4001 |
|
58 |
I |
A |
-0.1461 |
|
59 |
P |
A |
-0.3999 |
|
60 |
S |
A |
-0.5814 |
|
61 |
R |
A |
-1.0372 |
|
62 |
F |
A |
0.0000 |
|
63 |
S |
A |
-0.8870 |
|
64 |
G |
A |
-0.6950 |
|
65 |
S |
A |
-0.8292 |
|
66 |
G |
A |
-1.1446 |
|
67 |
S |
A |
-1.2047 |
|
68 |
G |
A |
-1.4735 |
|
69 |
T |
A |
-2.0844 |
|
70 |
D |
A |
-2.8392 |
|
71 |
F |
A |
0.0000 |
|
72 |
T |
A |
-0.9449 |
|
73 |
L |
A |
0.0000 |
|
74 |
S |
A |
0.0000 |
|
75 |
I |
A |
0.0000 |
|
76 |
N |
A |
-2.4287 |
|
77 |
S |
A |
-2.3570 |
|
78 |
V |
A |
0.0000 |
|
79 |
E |
A |
-2.5902 |
|
80 |
S |
A |
-2.3326 |
|
81 |
E |
A |
-2.6578 |
|
82 |
D |
A |
0.0000 |
|
83 |
I |
A |
0.0000 |
|
84 |
A |
A |
0.0000 |
|
85 |
D |
A |
-0.5401 |
|
86 |
Y |
A |
0.0000 |
|
87 |
Y |
A |
0.3130 |
|
88 |
C |
A |
0.0000 |
|
89 |
Q |
A |
0.4809 |
|
90 |
Q |
A |
0.0000 |
|
91 |
N |
A |
-0.8942 |
|
92 |
N |
A |
-1.4956 |
|
93 |
N |
A |
-1.3781 |
|
94 |
W |
A |
0.0494 |
|
95 |
P |
A |
-0.1404 |
|
96 |
T |
A |
-0.3600 |
|
97 |
T |
A |
0.3769 |
|
98 |
F |
A |
1.5695 |
|
99 |
G |
A |
0.7257 |
|
100 |
A |
A |
0.6977 |
|
101 |
G |
A |
0.4870 |
|
102 |
T |
A |
0.0000 |
|
103 |
K |
A |
0.0572 |
|
104 |
L |
A |
0.0000 |
|
105 |
E |
A |
0.0000 |
|
106 |
L |
A |
0.0000 |
|
107 |
K |
A |
-1.4245 |
|
108 |
R |
A |
-1.1637 |
|
109 |
T |
A |
-0.2004 |
|
110 |
V |
A |
0.2768 |
|
111 |
A |
A |
-0.1272 |
|
112 |
A |
A |
-0.2123 |
|
113 |
P |
A |
0.0000 |
|
114 |
S |
A |
-0.1413 |
|
115 |
V |
A |
0.0000 |
|
116 |
F |
A |
1.2406 |
|
117 |
I |
A |
1.2773 |
|
118 |
F |
A |
1.5005 |
|
119 |
P |
A |
0.0553 |
|
120 |
P |
A |
0.0000 |
|
121 |
S |
A |
-1.7825 |
|
122 |
D |
A |
-3.2241 |
|
123 |
E |
A |
-3.4391 |
|
124 |
Q |
A |
-2.4699 |
|
125 |
L |
A |
-2.5395 |
|
126 |
K |
A |
-3.0694 |
|
127 |
S |
A |
-1.9243 |
|
128 |
G |
A |
-1.4967 |
|
129 |
T |
A |
-1.1838 |
|
130 |
A |
A |
0.0000 |
|
131 |
S |
A |
0.0506 |
|
132 |
V |
A |
0.0000 |
|
133 |
V |
A |
0.7658 |
|
134 |
C |
A |
0.0000 |
|
135 |
L |
A |
0.5148 |
|
136 |
L |
A |
0.0000 |
|
137 |
N |
A |
-0.5581 |
|
138 |
N |
A |
-1.1957 |
|
139 |
F |
A |
0.0000 |
|
140 |
Y |
A |
0.0000 |
|
141 |
P |
A |
-1.4110 |
|
142 |
R |
A |
-2.1360 |
|
143 |
E |
A |
-2.6696 |
|
144 |
A |
A |
-1.8832 |
|
145 |
K |
A |
-2.1179 |
|
146 |
V |
A |
-1.0674 |
|
147 |
Q |
A |
-0.6563 |
|
148 |
W |
A |
0.0000 |
|
149 |
K |
A |
-0.7013 |
|
150 |
V |
A |
0.0000 |
|
151 |
D |
A |
-2.1899 |
|
152 |
N |
A |
-1.6512 |
|
153 |
A |
A |
-0.3577 |
|
154 |
L |
A |
0.5821 |
|
155 |
Q |
A |
-0.4929 |
|
156 |
S |
A |
-0.7076 |
|
157 |
G |
A |
-1.3877 |
|
158 |
N |
A |
-1.7425 |
|
159 |
S |
A |
-1.8352 |
|
160 |
Q |
A |
-2.4660 |
|
161 |
E |
A |
-2.1678 |
|
162 |
S |
A |
-0.9332 |
|
163 |
V |
A |
-0.0266 |
|
164 |
T |
A |
-0.8197 |
|
165 |
E |
A |
-2.2291 |
|
166 |
Q |
A |
0.0000 |
|
167 |
D |
A |
-2.5944 |
|
168 |
S |
A |
-2.6599 |
|
169 |
K |
A |
-2.7949 |
|
170 |
D |
A |
-2.0171 |
|
171 |
S |
A |
0.0000 |
|
172 |
T |
A |
0.0000 |
|
173 |
Y |
A |
0.0000 |
|
174 |
S |
A |
-0.6620 |
|
175 |
L |
A |
0.0000 |
|
176 |
S |
A |
-0.3385 |
|
177 |
S |
A |
0.0000 |
|
178 |
T |
A |
-0.7514 |
|
179 |
L |
A |
0.0000 |
|
180 |
T |
A |
-0.7393 |
|
181 |
L |
A |
-0.8581 |
|
182 |
S |
A |
-1.2631 |
|
183 |
K |
A |
-2.1119 |
|
184 |
A |
A |
-1.8547 |
|
185 |
D |
A |
-2.5797 |
|
186 |
Y |
A |
0.0000 |
|
187 |
E |
A |
-3.2358 |
|
188 |
K |
A |
-3.5405 |
|
189 |
H |
A |
-3.0344 |
|
190 |
K |
A |
-3.1944 |
|
191 |
V |
A |
-1.7614 |
|
192 |
Y |
A |
0.0000 |
|
193 |
A |
A |
0.0000 |
|
194 |
C |
A |
0.0000 |
|
195 |
E |
A |
-0.7431 |
|
196 |
V |
A |
0.0000 |
|
197 |
T |
A |
-1.1254 |
|
198 |
H |
A |
0.0000 |
|
199 |
Q |
A |
-1.6793 |
|
200 |
G |
A |
-0.4630 |
|
201 |
L |
A |
-0.2115 |
|
202 |
S |
A |
-0.4505 |
|
203 |
S |
A |
-0.4231 |
|
204 |
P |
A |
-0.5846 |
|
205 |
V |
A |
-0.1165 |
|
206 |
T |
A |
-0.4162 |
|
207 |
K |
A |
-0.2710 |
|
208 |
S |
A |
-0.3070 |
|
209 |
F |
A |
-0.5654 |
|
210 |
N |
A |
-1.7104 |
|
211 |
R |
A |
-2.0691 |
|
212 |
G |
A |
-1.2800 |
|
213 |
A |
A |
-0.7266 |
|