Chain sequence(s) |
A: MQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKT B: MQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKT |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
0 | M | A | 0.0540 | |
1 | Q | A | -1.6000 | |
2 | D | A | -2.0596 | |
3 | P | A | -1.4323 | |
4 | Y | A | 0.0000 | |
5 | V | A | -1.5147 | |
6 | K | A | -2.1809 | |
7 | E | A | 0.0000 | |
8 | A | A | 0.0000 | |
9 | E | A | -2.2224 | |
10 | N | A | -1.9507 | |
11 | L | A | 0.0000 | |
12 | K | A | -2.2692 | |
13 | K | A | -2.5972 | |
14 | Y | A | -0.7778 | |
15 | F | A | -1.0832 | |
16 | N | A | -2.1267 | |
17 | A | A | 0.0000 | |
18 | G | A | -2.1220 | |
19 | H | A | -2.1057 | |
20 | S | A | -1.6244 | |
21 | D | A | -2.2175 | |
22 | V | A | 0.0000 | |
23 | A | A | -1.8615 | |
24 | D | A | -2.8497 | |
25 | N | A | -2.5047 | |
26 | G | A | -1.5706 | |
27 | T | A | -0.8767 | |
28 | L | A | 0.0000 | |
29 | F | A | 0.0000 | |
30 | L | A | -0.7555 | |
31 | G | A | -0.9379 | |
32 | I | A | 0.0000 | |
33 | L | A | 0.0000 | |
34 | K | A | -2.5528 | |
35 | N | A | -2.3077 | |
36 | W | A | 0.0000 | |
37 | K | A | -3.8748 | |
38 | E | A | -3.7757 | |
39 | E | A | -3.4922 | |
40 | S | A | -2.2819 | |
41 | D | A | -1.9224 | |
42 | R | A | -2.4540 | |
43 | K | A | 0.0000 | |
44 | I | A | 0.0000 | |
45 | M | A | 0.0000 | |
46 | Q | A | 0.0000 | |
47 | S | A | 0.0000 | |
48 | Q | A | 0.0000 | |
49 | I | A | 0.0000 | |
50 | V | A | 0.0000 | |
51 | S | A | -0.6365 | |
52 | F | A | 0.0000 | |
53 | Y | A | 0.0000 | |
54 | F | A | -1.3432 | |
55 | K | A | -2.2554 | |
56 | L | A | 0.0000 | |
57 | F | A | 0.0000 | |
58 | K | A | -3.3318 | |
59 | N | A | -2.9877 | |
60 | F | A | -2.6127 | |
61 | K | A | -3.2879 | |
62 | D | A | -3.3355 | |
63 | D | A | -2.7249 | |
64 | Q | A | -2.5874 | |
65 | S | A | -1.5232 | |
66 | I | A | 0.0000 | |
67 | Q | A | -2.4905 | |
68 | K | A | -2.6405 | |
69 | S | A | 0.0000 | |
70 | V | A | 0.0000 | |
71 | E | A | -3.2215 | |
72 | T | A | -2.3551 | |
73 | I | A | 0.0000 | |
74 | K | A | -2.1864 | |
75 | E | A | -2.3626 | |
76 | D | A | -1.4548 | |
77 | M | A | 0.0000 | |
78 | N | A | -1.1840 | |
79 | V | A | -0.0631 | |
80 | K | A | -0.6664 | |
81 | F | A | 0.0000 | |
82 | F | A | 0.0000 | |
83 | N | A | -1.4605 | |
84 | S | A | -1.5327 | |
85 | N | A | -2.5086 | |
86 | K | A | -3.3110 | |
87 | K | A | -3.4094 | |
88 | K | A | 0.0000 | |
89 | R | A | -2.9445 | |
90 | D | A | -3.3839 | |
91 | D | A | 0.0000 | |
92 | F | A | 0.0000 | |
93 | E | A | -2.9592 | |
94 | K | A | -2.8897 | |
95 | L | A | 0.0000 | |
96 | T | A | -1.7954 | |
97 | N | A | -1.9903 | |
98 | Y | A | -1.0011 | |
99 | S | A | -0.5089 | |
100 | V | A | -0.5274 | |
101 | T | A | -0.4325 | |
102 | D | A | -0.5730 | |
103 | L | A | 0.4251 | |
104 | N | A | -0.9809 | |
105 | V | A | -0.4010 | |
106 | Q | A | 0.0000 | |
107 | R | A | -1.2477 | |
108 | K | A | -1.3050 | |
109 | A | A | 0.0000 | |
110 | I | A | 0.0000 | |
111 | H | A | -1.4033 | |
112 | E | A | 0.0000 | |
113 | L | A | 0.0000 | |
114 | I | A | -0.8781 | |
115 | Q | A | -1.3058 | |
116 | V | A | 0.0000 | |
117 | M | A | 0.0000 | |
118 | A | A | -1.1087 | |
119 | E | A | -1.4835 | |
120 | L | A | 0.0000 | |
121 | S | A | -0.6807 | |
122 | P | A | -0.8065 | |
123 | A | A | -1.1878 | |
124 | A | A | -1.3061 | |
125 | K | A | -1.6946 | |
126 | T | A | -0.8800 | |
0 | M | B | -0.0027 | |
1 | Q | B | -1.9278 | |
2 | D | B | -2.5208 | |
3 | P | B | -1.7546 | |
4 | Y | B | 0.0000 | |
5 | V | B | 0.0000 | |
6 | K | B | -2.7281 | |
7 | E | B | 0.0000 | |
8 | A | B | 0.0000 | |
9 | E | B | -2.3178 | |
10 | N | B | -1.8980 | |
11 | L | B | 0.0000 | |
12 | K | B | 0.0000 | |
13 | K | B | -2.4566 | |
14 | Y | B | -0.6913 | |
15 | F | B | 0.0000 | |
16 | N | B | -2.3014 | |
17 | A | B | 0.0000 | |
18 | G | B | -2.1156 | |
19 | H | B | -2.2097 | |
20 | S | B | -1.6119 | |
21 | D | B | -2.4728 | |
22 | V | B | 0.0000 | |
23 | A | B | -1.9474 | |
24 | D | B | -2.9134 | |
25 | N | B | -2.5283 | |
26 | G | B | -1.5687 | |
27 | T | B | -0.8889 | |
28 | L | B | 0.0000 | |
29 | F | B | 0.0000 | |
30 | L | B | -0.8311 | |
31 | G | B | -0.9290 | |
32 | I | B | 0.0000 | |
33 | L | B | 0.0000 | |
34 | K | B | -2.3771 | |
35 | N | B | -2.3088 | |
36 | W | B | 0.0000 | |
37 | K | B | -3.2199 | |
38 | E | B | -2.9573 | |
39 | E | B | -2.0797 | |
40 | S | B | -1.8470 | |
41 | D | B | -1.5023 | |
42 | R | B | 0.0000 | |
43 | K | B | 0.0000 | |
44 | I | B | 0.0000 | |
45 | M | B | 0.0000 | |
46 | Q | B | 0.0000 | |
47 | S | B | 0.0000 | |
48 | Q | B | 0.0000 | |
49 | I | B | 0.0000 | |
50 | V | B | 0.0000 | |
51 | S | B | -0.5402 | |
52 | F | B | 0.0000 | |
53 | Y | B | 0.0000 | |
54 | F | B | -1.1610 | |
55 | K | B | -2.0437 | |
56 | L | B | 0.0000 | |
57 | F | B | 0.0000 | |
58 | K | B | -3.3387 | |
59 | N | B | -2.8010 | |
60 | F | B | -2.6976 | |
61 | K | B | -3.9065 | |
62 | D | B | -3.5108 | |
63 | D | B | -2.7646 | |
64 | Q | B | -2.6019 | |
65 | S | B | -1.5072 | |
66 | I | B | 0.0000 | |
67 | Q | B | -2.6922 | |
68 | K | B | -2.7086 | |
69 | S | B | 0.0000 | |
70 | V | B | 0.0000 | |
71 | E | B | -3.4025 | |
72 | T | B | -2.5095 | |
73 | I | B | 0.0000 | |
74 | K | B | -2.3608 | |
75 | E | B | -2.4632 | |
76 | D | B | -1.5659 | |
77 | M | B | 0.0000 | |
78 | N | B | -1.2443 | |
79 | V | B | -0.0833 | |
80 | K | B | -0.6774 | |
81 | F | B | 0.0000 | |
82 | F | B | 0.0000 | |
83 | N | B | -1.4896 | |
84 | S | B | -1.5124 | |
85 | N | B | -2.5358 | |
86 | K | B | -3.3220 | |
87 | K | B | -3.3028 | |
88 | K | B | 0.0000 | |
89 | R | B | -2.9779 | |
90 | D | B | -3.5854 | |
91 | D | B | 0.0000 | |
92 | F | B | 0.0000 | |
93 | E | B | -2.7633 | |
94 | K | B | -2.7716 | |
95 | L | B | 0.0000 | |
96 | T | B | -1.6828 | |
97 | N | B | -1.8817 | |
98 | Y | B | -0.9641 | |
99 | S | B | -0.5053 | |
100 | V | B | -0.5886 | |
101 | T | B | -0.4862 | |
102 | D | B | -0.5658 | |
103 | L | B | 0.4862 | |
104 | N | B | -0.8007 | |
105 | V | B | -0.3886 | |
106 | Q | B | -0.3243 | |
107 | R | B | -1.2075 | |
108 | K | B | -1.2590 | |
109 | A | B | 0.0000 | |
110 | I | B | 0.0000 | |
111 | H | B | -1.3772 | |
112 | E | B | 0.0000 | |
113 | L | B | 0.0000 | |
114 | I | B | -0.6950 | |
115 | Q | B | -1.0025 | |
116 | V | B | 0.0000 | |
117 | M | B | 0.0000 | |
118 | A | B | -0.9812 | |
119 | E | B | -1.8414 | |
120 | L | B | 0.0000 | |
121 | S | B | -0.8993 | |
122 | P | B | -1.6675 | |
123 | A | B | -1.4744 | |
124 | A | B | -0.8173 | |
125 | K | B | -1.7182 | |
126 | T | B | -1.9161 |