Project name: 6arp:D
Status: done
submitted: 2019-03-21 14:50:32, status changed: 2019-03-21 15:01:35
Settings
Chain sequence(s)
|
D: QVQLKQSGPGLVQPSQSLSSITCTVSGFDLTDYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNNSLQSNDTAIYYCARALTTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVVTVSWNSGALTSSGVHTFPAVLQSSGLYSLSSSVVTVPSSSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8753
-
Maximal score value
-
2.4729
-
Average score
-
-0.5625
-
Total score value
-
-122.0699
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
Q |
D |
-1.5099 |
|
2 |
V |
D |
-1.1178 |
|
3 |
Q |
D |
-1.7435 |
|
4 |
L |
D |
0.0000 |
|
5 |
K |
D |
-2.3493 |
|
6 |
Q |
D |
-1.4209 |
|
7 |
S |
D |
-0.8988 |
|
8 |
G |
D |
-1.1757 |
|
9 |
P |
D |
-0.5428 |
|
10 |
G |
D |
-0.4011 |
|
11 |
L |
D |
-0.0446 |
|
12 |
V |
D |
-0.8205 |
|
13 |
Q |
D |
-1.6561 |
|
14 |
P |
D |
-1.6199 |
|
15 |
S |
D |
-1.5158 |
|
16 |
Q |
D |
-1.8648 |
|
17 |
S |
D |
-1.7782 |
|
18 |
L |
D |
0.0000 |
|
19 |
S |
D |
-0.8684 |
|
20 |
I |
D |
0.0000 |
|
21 |
T |
D |
-0.6919 |
|
22 |
C |
D |
0.0000 |
|
23 |
T |
D |
-1.2487 |
|
24 |
V |
D |
0.0000 |
|
25 |
S |
D |
-1.6283 |
|
26 |
G |
D |
-1.3882 |
|
27 |
F |
D |
-1.5100 |
|
28 |
D |
D |
-2.6802 |
|
29 |
L |
D |
0.0000 |
|
30 |
T |
D |
-1.6897 |
|
31 |
D |
D |
-1.9168 |
|
32 |
Y |
D |
-0.2061 |
|
33 |
G |
D |
0.0000 |
|
34 |
V |
D |
0.0000 |
|
35 |
H |
D |
0.0000 |
|
36 |
W |
D |
0.0000 |
|
37 |
V |
D |
0.0000 |
|
38 |
R |
D |
-0.0998 |
|
39 |
Q |
D |
-0.4918 |
|
40 |
S |
D |
-1.0501 |
|
41 |
P |
D |
-1.2254 |
|
42 |
G |
D |
-1.5812 |
|
43 |
K |
D |
-2.1147 |
|
44 |
G |
D |
-0.9710 |
|
45 |
L |
D |
0.5361 |
|
46 |
E |
D |
-0.3327 |
|
47 |
W |
D |
0.1584 |
|
48 |
L |
D |
0.0000 |
|
49 |
G |
D |
0.0000 |
|
50 |
V |
D |
0.0000 |
|
51 |
I |
D |
0.0000 |
|
52 |
W |
D |
-0.6924 |
|
53 |
S |
D |
-1.0021 |
|
54 |
G |
D |
-1.3062 |
|
55 |
G |
D |
-1.5133 |
|
56 |
N |
D |
-1.9514 |
|
57 |
T |
D |
-1.5238 |
|
58 |
D |
D |
-1.5393 |
|
59 |
Y |
D |
-0.6844 |
|
60 |
N |
D |
-0.7481 |
|
61 |
T |
D |
-0.5326 |
|
62 |
P |
D |
-0.4673 |
|
63 |
F |
D |
0.0000 |
|
64 |
T |
D |
-0.6027 |
|
65 |
S |
D |
-0.5997 |
|
66 |
R |
D |
-1.0590 |
|
67 |
L |
D |
0.0000 |
|
68 |
S |
D |
-1.2428 |
|
69 |
I |
D |
0.0000 |
|
70 |
N |
D |
-1.8629 |
|
71 |
K |
D |
-1.4885 |
|
72 |
D |
D |
-1.7447 |
|
73 |
N |
D |
-2.4334 |
|
74 |
S |
D |
-1.8208 |
|
75 |
K |
D |
-2.4948 |
|
76 |
S |
D |
-1.9111 |
|
77 |
Q |
D |
-1.5409 |
|
78 |
V |
D |
0.0000 |
|
79 |
F |
D |
-0.5987 |
|
80 |
F |
D |
0.0000 |
|
81 |
K |
D |
-1.9421 |
|
82 |
M |
D |
0.0000 |
|
83 |
N |
D |
-1.9165 |
|
84 |
S |
D |
-1.4725 |
|
85 |
L |
D |
0.0000 |
|
86 |
Q |
D |
-2.0563 |
|
87 |
S |
D |
-1.5049 |
|
88 |
N |
D |
-1.7458 |
|
89 |
D |
D |
0.0000 |
|
90 |
T |
D |
-0.5786 |
|
91 |
A |
D |
0.0000 |
|
92 |
I |
D |
0.5930 |
|
93 |
Y |
D |
0.0000 |
|
94 |
Y |
D |
0.0370 |
|
95 |
C |
D |
0.0000 |
|
96 |
A |
D |
0.0000 |
|
97 |
R |
D |
0.0000 |
|
98 |
A |
D |
0.0000 |
|
99 |
L |
D |
1.8111 |
|
100 |
T |
D |
1.3355 |
|
101 |
Y |
D |
1.7993 |
|
102 |
Y |
D |
1.6995 |
|
103 |
D |
D |
0.7767 |
|
104 |
Y |
D |
0.7730 |
|
105 |
E |
D |
-0.0187 |
|
106 |
F |
D |
0.6043 |
|
107 |
A |
D |
0.7773 |
|
108 |
Y |
D |
0.4997 |
|
109 |
W |
D |
0.0179 |
|
110 |
G |
D |
0.0000 |
|
111 |
Q |
D |
-1.5609 |
|
112 |
G |
D |
-0.6837 |
|
113 |
T |
D |
0.0000 |
|
114 |
L |
D |
0.1220 |
|
115 |
V |
D |
0.0000 |
|
116 |
T |
D |
-0.3192 |
|
117 |
V |
D |
0.0000 |
|
118 |
S |
D |
-0.5819 |
|
119 |
A |
D |
-0.3961 |
|
120 |
A |
D |
-0.2752 |
|
121 |
S |
D |
-0.4688 |
|
122 |
T |
D |
-0.5983 |
|
123 |
K |
D |
-1.0281 |
|
124 |
G |
D |
-1.3076 |
|
125 |
P |
D |
0.0000 |
|
126 |
S |
D |
-0.0514 |
|
127 |
V |
D |
0.0000 |
|
128 |
F |
D |
0.9426 |
|
129 |
P |
D |
-0.1194 |
|
130 |
L |
D |
0.2810 |
|
131 |
A |
D |
-0.9364 |
|
132 |
P |
D |
0.0000 |
|
133 |
S |
D |
-0.8934 |
|
134 |
S |
D |
-0.5302 |
|
139 |
G |
D |
-0.7653 |
|
140 |
G |
D |
-0.8825 |
|
141 |
T |
D |
-0.6183 |
|
142 |
A |
D |
0.0000 |
|
143 |
A |
D |
0.0686 |
|
144 |
L |
D |
0.0000 |
|
145 |
G |
D |
0.0000 |
|
146 |
C |
D |
0.0000 |
|
147 |
L |
D |
0.6986 |
|
148 |
V |
D |
0.0000 |
|
149 |
K |
D |
-0.1866 |
|
150 |
D |
D |
-0.5559 |
|
151 |
Y |
D |
0.0000 |
|
152 |
F |
D |
-0.2076 |
|
153 |
P |
D |
0.0000 |
|
154 |
E |
D |
-0.4661 |
|
155 |
P |
D |
-0.6877 |
|
156 |
V |
D |
-0.6549 |
|
157 |
T |
D |
-0.5965 |
|
158 |
V |
D |
-0.3754 |
|
159 |
S |
D |
-0.3697 |
|
160 |
W |
D |
0.0000 |
|
161 |
N |
D |
-0.8548 |
|
162 |
S |
D |
-0.6283 |
|
163 |
G |
D |
-0.5438 |
|
164 |
A |
D |
-0.2492 |
|
165 |
L |
D |
-0.0426 |
|
166 |
T |
D |
-0.3214 |
|
167 |
S |
D |
-0.3590 |
|
168 |
G |
D |
-0.4293 |
|
169 |
V |
D |
-0.1442 |
|
170 |
H |
D |
-0.6275 |
|
171 |
T |
D |
0.0018 |
|
172 |
F |
D |
0.7878 |
|
173 |
P |
D |
0.6525 |
|
174 |
A |
D |
1.2244 |
|
175 |
V |
D |
2.4729 |
|
176 |
L |
D |
2.0994 |
|
177 |
Q |
D |
0.6991 |
|
178 |
S |
D |
0.0930 |
|
179 |
S |
D |
-0.2186 |
|
180 |
G |
D |
0.2419 |
|
181 |
L |
D |
0.3571 |
|
182 |
Y |
D |
0.8338 |
|
183 |
S |
D |
0.7107 |
|
184 |
L |
D |
0.0000 |
|
185 |
S |
D |
0.5931 |
|
186 |
S |
D |
0.0000 |
|
187 |
V |
D |
0.3052 |
|
188 |
V |
D |
0.0000 |
|
189 |
T |
D |
-0.2267 |
|
190 |
V |
D |
0.0000 |
|
191 |
P |
D |
-0.5605 |
|
192 |
S |
D |
-0.6391 |
|
193 |
S |
D |
-0.6237 |
|
194 |
S |
D |
0.0000 |
|
195 |
L |
D |
-0.8581 |
|
196 |
G |
D |
-0.9803 |
|
197 |
T |
D |
-0.7352 |
|
198 |
Q |
D |
-1.2697 |
|
199 |
T |
D |
-1.1742 |
|
200 |
Y |
D |
0.0000 |
|
201 |
I |
D |
-1.3751 |
|
202 |
C |
D |
0.0000 |
|
203 |
N |
D |
-1.3582 |
|
204 |
V |
D |
0.0000 |
|
205 |
N |
D |
-1.9644 |
|
206 |
H |
D |
0.0000 |
|
207 |
K |
D |
-2.7470 |
|
208 |
P |
D |
-1.5369 |
|
209 |
S |
D |
-1.7166 |
|
210 |
N |
D |
-2.5536 |
|
211 |
T |
D |
-2.0369 |
|
212 |
K |
D |
-2.6006 |
|
213 |
V |
D |
-1.3785 |
|
214 |
D |
D |
-2.1106 |
|
215 |
K |
D |
-1.9711 |
|
216 |
K |
D |
-2.4296 |
|
217 |
V |
D |
0.0000 |
|
218 |
E |
D |
-2.8753 |
|
219 |
P |
D |
-1.9704 |
|
220 |
K |
D |
-2.3665 |
|
221 |
S |
D |
-1.3286 |
|