Project name: 2IV1 [mutate: KA24L, KA25L, DA26L, KB24L, KB25L, DB26L, KC24L, KC25L, DC26L, KD24L, KD25L, DD26L, KE24L, KE25L, DE26L, KF24L, KF25L, DF26L, KG24L, KG25L, DG26L, KH24L, DH26L, KH25L, KI24L, KI25L, DI26L, KJ24L, KJ25L, DJ26L]

Status: done

submitted: 2017-09-12 23:41:19, status changed: 2017-09-13 01:02:11
Settings
Chain sequence(s) A: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYQFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
C: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYQFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
B: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYQFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
E: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYQFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
D: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYQFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
G: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYQFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
F: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYQFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
I: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYQFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
H: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYQFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
J: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYQFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
Distance of aggregation 10 Å
Dynamic mode No
Mutated residues KA24L, KA25L, DA26L, KB24L, KB25L, DB26L, KC24L, KC25L, DC26L, KD24L, KD25L, DD26L, KE24L, KE25L, DE26L, KF24L, KF25L, DF26L, KG24L, KG25L, DG26L, KH24L, DH26L, KH25L, KI24L, KI25L, DI26L, KJ24L, KJ25L, DJ26L
Energy difference between WT (input) and mutated protein (by FoldX) -6.20477 kcal/mol
Show buried residues

Minimal score value
-3.7102
Maximal score value
3.034
Average score
-0.5345
Total score value
-833.8359

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
1 M A 1.8365
2 I A 1.1321
3 Q A 0.0000
4 S A 0.0000
5 Q A 0.0000
6 I A -0.2329
7 N A -1.0466
8 R A -1.1825
9 N A -1.6475
10 I A -0.7119
11 R A 0.0000
12 L A -1.0995
13 D A -2.0188
14 L A 0.0000
15 A A 0.0000
16 D A -0.7669
17 A A -0.3652
18 I A 0.0000
19 L A 0.0000
20 L A 0.6922
21 S A 0.7582
22 K A 0.0000
23 A A 0.0000
24 L A 2.1477 mutated: KA24L
25 L A 2.4281 mutated: KA25L
26 L A 3.0340 mutated: DA26L
27 L A 1.4668
28 S A 0.0000
29 F A 0.0000
30 A A -1.6488
31 E A -2.4241
32 I A 0.0000
33 A A 0.0000
34 D A -2.7842
35 G A -1.6055
36 T A -1.6517
37 G A -0.9621
38 L A -0.5696
39 A A -1.0969
40 E A -1.9239
41 A A 0.0000
42 F A 0.0000
43 V A 0.0000
44 T A 0.0000
45 A A 0.0000
46 A A 0.0000
47 L A 0.0000
48 L A 0.0000
49 G A 0.0000
50 Q A 0.0000
51 Q A 0.0000
52 A A -0.3364
53 L A 0.0000
54 P A -0.9412
55 A A -1.3006
56 D A -2.3176
57 A A 0.0000
58 A A 0.0000
59 R A -2.6079
60 L A -1.3812
61 V A 0.0000
62 G A 0.0000
63 A A -1.2827
64 K A -1.1041
65 L A 0.0000
66 D A -2.4306
67 L A -2.4096
68 D A -3.2958
69 E A -3.4231
70 D A -2.2964
71 S A -1.9305
72 I A -1.8764
73 L A -0.8602
74 L A -0.1354
75 L A 0.0000
76 Q A -0.4192
77 M A 0.0000
78 I A 0.0000
79 P A 0.0000
80 L A -0.0512
81 R A 0.0000
82 G A 0.0000
83 C A 0.0000
84 I A 0.0000
85 D A -2.8229
86 D A -3.2898
87 R A -1.9416
88 I A 0.0000
89 P A 0.0000
90 T A -0.8282
91 D A 0.0000
92 P A 0.0000
93 T A 0.0000
94 M A 0.0000
95 Y A 0.0000
96 Q A 0.0000
97 F A 0.0000
98 Y A 0.0000
99 E A 0.0000
100 M A 0.0000
101 L A 0.0000
102 Q A 0.0000
103 V A 0.0000
104 Y A 0.0000
105 G A 0.0000
106 T A 0.0000
107 T A 0.0000
108 L A 0.0000
109 K A 0.0000
110 A A 0.0000
111 L A 0.0000
112 V A 0.0000
113 H A 0.0000
114 E A -0.1440
115 K A -1.0898
116 F A -0.6816
117 G A -0.2614
118 D A -0.5416
119 G A 0.0000
120 I A 0.0000
121 I A 0.0000
122 S A 0.0000
123 A A 0.0000
124 I A -0.6912
125 N A -1.3585
126 F A 0.0000
127 K A -1.9338
128 L A 0.0000
129 D A -2.5679
130 V A 0.0000
131 K A -2.7181
132 K A -2.3061
133 V A -0.9326
134 A A -0.8917
135 D A 0.0000
136 P A -1.3693
137 E A -2.2886
138 G A -1.6939
139 G A -1.3640
140 E A -1.5079
141 R A 0.0000
142 A A 0.0000
143 V A -1.1246
144 I A 0.0000
145 T A -1.1644
146 L A 0.0000
147 D A -1.2530
148 G A 0.0000
149 K A -1.0518
150 Y A -0.6226
151 L A -0.5506
152 P A -0.8941
153 T A -1.0336
154 K A -1.9235
155 P A -0.8358
156 F A -0.3216
1 M B 1.8899
2 I B 1.0987
3 Q B 0.0000
4 S B 0.0000
5 Q B 0.0000
6 I B -0.3008
7 N B -1.1425
8 R B -1.2729
9 N B -1.7709
10 I B -0.9466
11 R B 0.0000
12 L B -1.1355
13 D B -2.0298
14 L B 0.0000
15 A B 0.0000
16 D B 0.0000
17 A B -0.2722
18 I B 0.0000
19 L B 0.0000
20 L B 0.7016
21 S B 0.6806
22 K B 0.0000
23 A B 0.0000
24 L B 1.9401 mutated: KB24L
25 L B 2.1829 mutated: KB25L
26 L B 2.7291 mutated: DB26L
27 L B 1.3983
28 S B 0.0000
29 F B 0.0000
30 A B -1.3788
31 E B -2.0252
32 I B 0.0000
33 A B 0.0000
34 D B -2.6224
35 G B -1.5443
36 T B -1.6118
37 G B -0.9162
38 L B -0.4967
39 A B -1.0067
40 E B -1.7495
41 A B 0.0000
42 F B 0.0000
43 V B 0.0000
44 T B 0.0000
45 A B 0.0000
46 A B 0.0000
47 L B 0.0000
48 L B 0.0000
49 G B 0.0000
50 Q B 0.0000
51 Q B 0.0000
52 A B -0.3676
53 L B 0.0000
54 P B -1.1144
55 A B -1.3191
56 D B -2.3272
57 A B 0.0000
58 A B 0.0000
59 R B -2.6198
60 L B -1.4137
61 V B 0.0000
62 G B 0.0000
63 A B -1.3203
64 K B -1.0745
65 L B 0.0000
66 D B -2.4419
67 L B -2.4265
68 D B -3.3538
69 E B -3.4890
70 D B -2.4381
71 S B -2.0001
72 I B -1.9632
73 L B -0.8980
74 L B -0.2042
75 L B 0.0000
76 Q B -0.4978
77 M B 0.0000
78 I B 0.0000
79 P B 0.0000
80 L B -0.0765
81 R B 0.0000
82 G B 0.0000
83 C B 0.0000
84 I B 0.0000
85 D B -2.3027
86 D B -3.1167
87 R B -1.9948
88 I B 0.0000
89 P B 0.0000
90 T B 0.0000
91 D B 0.0000
92 P B 0.0000
93 T B 0.0000
94 M B 0.0000
95 Y B 0.0000
96 Q B 0.0000
97 F B 0.0000
98 Y B 0.0000
99 E B 0.0000
100 M B 0.0000
101 L B 0.0000
102 Q B 0.0000
103 V B 0.0000
104 Y B 0.0000
105 G B 0.0000
106 T B 0.0000
107 T B 0.0000
108 L B 0.0000
109 K B 0.0000
110 A B 0.0000
111 L B 0.0000
112 V B 0.0000
113 H B 0.0000
114 E B -0.2676
115 K B -1.2866
116 F B -0.8432
117 G B -0.3372
118 D B -0.5782
119 G B 0.0000
120 I B 0.0000
121 I B 0.0000
122 S B 0.0000
123 A B 0.0000
124 I B -0.6519
125 N B -1.2777
126 F B 0.0000
127 K B -1.7929
128 L B 0.0000
129 D B -2.5546
130 V B 0.0000
131 K B -2.6180
132 K B -2.1146
133 V B -0.8608
134 A B -0.9228
135 D B 0.0000
136 P B -1.3913
137 E B -2.3157
138 G B -1.7857
139 G B -1.4408
140 E B -1.5717
141 R B -1.3344
142 A B 0.0000
143 V B -1.1279
144 I B 0.0000
145 T B -0.9203
146 L B 0.0000
147 D B 0.0000
148 G B 0.0000
149 K B -1.0103
150 Y B 0.0000
151 L B -0.6000
152 P B -0.9202
153 T B -1.0474
154 K B -1.9119
155 P B -0.8026
156 F B -0.2443
1 M C 1.8551
2 I C 1.1916
3 Q C 0.0000
4 S C 0.0000
5 Q C 0.0000
6 I C 0.0000
7 N C -1.2304
8 R C -1.3060
9 N C -1.7860
10 I C -0.9667
11 R C 0.0000
12 L C -1.1280
13 D C -2.0201
14 L C 0.0000
15 A C 0.0000
16 D C 0.0000
17 A C -0.2659
18 I C 0.0000
19 L C 0.0000
20 L C 0.6321
21 S C 0.6089
22 K C 0.0000
23 A C 0.0000
24 L C 1.7188 mutated: KC24L
25 L C 2.0310 mutated: KC25L
26 L C 2.7451 mutated: DC26L
27 L C 1.3997
28 S C 0.0000
29 F C 0.0000
30 A C -1.3847
31 E C -1.9880
32 I C 0.0000
33 A C 0.0000
34 D C -2.6254
35 G C -1.5481
36 T C -1.6557
37 G C -0.9481
38 L C -0.5000
39 A C -1.0240
40 E C -1.8312
41 A C 0.0000
42 F C 0.0000
43 V C 0.0000
44 T C 0.0000
45 A C 0.0000
46 A C 0.0000
47 L C 0.0000
48 L C 0.0000
49 G C 0.0000
50 Q C 0.0000
51 Q C 0.0000
52 A C -0.3555
53 L C 0.0000
54 P C -1.0779
55 A C -1.3237
56 D C -2.3232
57 A C 0.0000
58 A C 0.0000
59 R C -2.8530
60 L C -1.4723
61 V C 0.0000
62 G C 0.0000
63 A C -1.3325
64 K C -1.0696
65 L C 0.0000
66 D C -2.4984
67 L C -2.4929
68 D C -3.5793
69 E C -3.5664
70 D C -2.4586
71 S C -2.0687
72 I C 0.0000
73 L C -1.0200
74 L C -0.2716
75 L C 0.0000
76 Q C -0.4933
77 M C 0.0000
78 I C 0.0000
79 P C 0.0000
80 L C -0.1423
81 R C 0.0000
82 G C 0.0000
83 C C 0.0000
84 I C 0.0000
85 D C -1.6064
86 D C -2.2268
87 R C -1.3017
88 I C 0.0000
89 P C 0.0000
90 T C -0.5815
91 D C 0.0000
92 P C 0.0000
93 T C 0.0000
94 M C 0.0000
95 Y C 0.0000
96 Q C 0.0000
97 F C 0.0000
98 Y C 0.0000
99 E C 0.0000
100 M C 0.0000
101 L C 0.0000
102 Q C 0.0000
103 V C 0.0000
104 Y C 0.0000
105 G C 0.0000
106 T C 0.0000
107 T C 0.0000
108 L C 0.0000
109 K C 0.0000
110 A C 0.0000
111 L C 0.0000
112 V C 0.0000
113 H C 0.0000
114 E C -0.0919
115 K C -0.9484
116 F C -0.6487
117 G C -0.2236
118 D C -0.5335
119 G C 0.0000
120 I C 0.0000
121 I C 0.0000
122 S C 0.0000
123 A C 0.0000
124 I C -0.5021
125 N C -0.8900
126 F C 0.0000
127 K C -1.6930
128 L C 0.0000
129 D C -2.5932
130 V C 0.0000
131 K C -2.5855
132 K C -1.9940
133 V C -0.8129
134 A C -0.8509
135 D C 0.0000
136 P C -1.3852
137 E C -2.2849
138 G C -1.7100
139 G C -1.3848
140 E C -1.4702
141 R C -1.1697
142 A C 0.0000
143 V C -1.0878
144 I C 0.0000
145 T C -1.0731
146 L C 0.0000
147 D C 0.0000
148 G C 0.0000
149 K C -0.8302
150 Y C 0.0000
151 L C -0.4494
152 P C -0.7566
153 T C -0.9711
154 K C -1.7771
155 P C -0.9361
156 F C -0.3714
1 M D 1.8395
2 I D 1.1085
3 Q D 0.0000
4 S D 0.0000
5 Q D 0.0000
6 I D 0.0000
7 N D -1.2324
8 R D -1.3083
9 N D -1.8301
10 I D -1.1875
11 R D 0.0000
12 L D -1.2023
13 D D -2.0900
14 L D 0.0000
15 A D 0.0000
16 D D -0.6601
17 A D -0.3560
18 I D 0.0000
19 L D 0.0000
20 L D 0.7076
21 S D 0.7570
22 K D 0.0000
23 A D 0.0000
24 L D 2.1647 mutated: KD24L
25 L D 2.3080 mutated: KD25L
26 L D 2.9600 mutated: DD26L
27 L D 1.4012
28 S D 0.0000
29 F D 0.0000
30 A D -1.4554
31 E D -2.0936
32 I D 0.0000
33 A D 0.0000
34 D D -2.6472
35 G D -1.5622
36 T D -1.6179
37 G D -1.1051
38 L D -0.4912
39 A D -1.0539
40 E D -1.7794
41 A D 0.0000
42 F D 0.0000
43 V D 0.0000
44 T D 0.0000
45 A D 0.0000
46 A D 0.0000
47 L D 0.0000
48 L D 0.0000
49 G D 0.0000
50 Q D 0.0000
51 Q D 0.0000
52 A D -0.3979
53 L D 0.0000
54 P D -1.1231
55 A D -1.3450
56 D D -2.3939
57 A D 0.0000
58 A D 0.0000
59 R D -2.9108
60 L D -1.4805
61 V D 0.0000
62 G D 0.0000
63 A D -1.3584
64 K D -1.1635
65 L D 0.0000
66 D D -2.5225
67 L D -2.4125
68 D D -3.4844
69 E D -3.4122
70 D D -2.0902
71 S D -2.0045
72 I D 0.0000
73 L D -0.9633
74 L D 0.0000
75 L D 0.0000
76 Q D -0.6334
77 M D 0.0000
78 I D 0.0000
79 P D 0.0000
80 L D 0.0000
81 R D 0.0000
82 G D 0.0000
83 C D 0.0000
84 I D 0.0000
85 D D -1.8657
86 D D -2.8069
87 R D -1.5705
88 I D 0.0000
89 P D 0.0000
90 T D 0.0000
91 D D 0.0000
92 P D 0.0000
93 T D 0.0000
94 M D 0.0000
95 Y D 0.0000
96 Q D 0.0000
97 F D 0.0000
98 Y D 0.0000
99 E D 0.0000
100 M D 0.0000
101 L D 0.0000
102 Q D 0.0000
103 V D 0.0000
104 Y D 0.0000
105 G D 0.0000
106 T D 0.0000
107 T D 0.0000
108 L D 0.0000
109 K D 0.0000
110 A D 0.0000
111 L D 0.0000
112 V D 0.0000
113 H D 0.0000
114 E D -0.2455
115 K D -1.2601
116 F D -0.7876
117 G D -0.4369
118 D D -0.5828
119 G D 0.0000
120 I D 0.0000
121 I D 0.0000
122 S D 0.0000
123 A D 0.0000
124 I D -0.6250
125 N D -1.1874
126 F D 0.0000
127 K D -1.7049
128 L D 0.0000
129 D D -2.5652
130 V D 0.0000
131 K D -2.6709
132 K D -2.2907
133 V D -0.9962
134 A D -0.9903
135 D D 0.0000
136 P D -1.3982
137 E D -2.3035
138 G D -1.7340
139 G D -1.4195
140 E D -1.6670
141 R D -1.3636
142 A D 0.0000
143 V D -1.2801
144 I D 0.0000
145 T D -1.1209
146 L D 0.0000
147 D D 0.0000
148 G D 0.0000
149 K D -0.8912
150 Y D 0.0000
151 L D -0.5765
152 P D -0.8799
153 T D -1.0574
154 K D -1.9252
155 P D -0.8222
156 F D -0.2642
1 M E 1.8302
2 I E 1.2169
3 Q E 0.0000
4 S E 0.0000
5 Q E 0.0000
6 I E -0.2679
7 N E -1.0895
8 R E -1.2193
9 N E -1.6933
10 I E -0.7566
11 R E 0.0000
12 L E -1.1392
13 D E -2.0260
14 L E 0.0000
15 A E 0.0000
16 D E -0.8055
17 A E -0.3721
18 I E 0.0000
19 L E 0.0000
20 L E 0.6510
21 S E 0.7154
22 K E 0.0000
23 A E 0.0000
24 L E 2.0905 mutated: KE24L
25 L E 2.2646 mutated: KE25L
26 L E 2.9771 mutated: DE26L
27 L E 1.4369
28 S E 0.0000
29 F E 0.0000
30 A E -1.5360
31 E E -2.1487
32 I E 0.0000
33 A E 0.0000
34 D E -2.6756
35 G E -1.5576
36 T E -1.6468
37 G E -0.9691
38 L E -0.5556
39 A E -1.1230
40 E E -1.8542
41 A E 0.0000
42 F E 0.0000
43 V E 0.0000
44 T E 0.0000
45 A E 0.0000
46 A E 0.0000
47 L E 0.0000
48 L E 0.0000
49 G E 0.0000
50 Q E 0.0000
51 Q E 0.0000
52 A E -0.3405
53 L E 0.0000
54 P E -1.1052
55 A E -1.2927
56 D E -2.3088
57 A E 0.0000
58 A E 0.0000
59 R E -2.7929
60 L E -1.3815
61 V E 0.0000
62 G E 0.0000
63 A E -1.2776
64 K E -1.0822
65 L E 0.0000
66 D E -2.4585
67 L E -2.3618
68 D E -3.4868
69 E E -3.4094
70 D E -2.2684
71 S E -1.9467
72 I E -1.8735
73 L E -0.7993
74 L E -0.1010
75 L E 0.0000
76 Q E -0.3734
77 M E 0.0000
78 I E 0.0000
79 P E 0.0000
80 L E 0.0000
81 R E 0.0000
82 G E 0.0000
83 C E 0.0000
84 I E 0.0000
85 D E -2.6968
86 D E -3.0023
87 R E -1.6388
88 I E -0.8457
89 P E 0.0000
90 T E -0.6269
91 D E 0.0000
92 P E 0.0000
93 T E 0.0000
94 M E 0.0000
95 Y E 0.0000
96 Q E 0.0000
97 F E 0.0000
98 Y E 0.0000
99 E E 0.0000
100 M E 0.0000
101 L E 0.0000
102 Q E 0.0000
103 V E 0.0000
104 Y E 0.0000
105 G E 0.0000
106 T E 0.0000
107 T E 0.0000
108 L E 0.0000
109 K E 0.0000
110 A E 0.0000
111 L E 0.0000
112 V E 0.0000
113 H E 0.0000
114 E E -0.2196
115 K E -1.1423
116 F E -0.6901
117 G E -0.3657
118 D E -0.5258
119 G E 0.0000
120 I E 0.0000
121 I E 0.0000
122 S E 0.0000
123 A E -0.4038
124 I E -0.6801
125 N E -1.3011
126 F E 0.0000
127 K E -2.2504
128 L E 0.0000
129 D E -2.6792
130 V E 0.0000
131 K E -2.4732
132 K E -1.8125
133 V E -0.6705
134 A E -0.8155
135 D E 0.0000
136 P E -1.3814
137 E E -2.3005
138 G E -1.7402
139 G E -1.3763
140 E E -1.4023
141 R E -1.0880
142 A E 0.0000
143 V E -1.0619
144 I E 0.0000
145 T E -1.0951
146 L E 0.0000
147 D E -1.4985
148 G E 0.0000
149 K E -1.0338
150 Y E -0.5485
151 L E -0.4534
152 P E -0.7379
153 T E -0.9274
154 K E -1.8539
155 P E -0.8366
156 F E -0.1424
1 M F 1.7359
2 I F 1.1898
3 Q F 0.0000
4 S F 0.0000
5 Q F 0.0000
6 I F 0.0000
7 N F -1.1348
8 R F -1.2703
9 N F -1.6981
10 I F -0.7804
11 R F 0.0000
12 L F -1.1705
13 D F -2.0256
14 L F 0.0000
15 A F 0.0000
16 D F -0.8343
17 A F -0.3353
18 I F 0.0000
19 L F 0.0000
20 L F 0.7828
21 S F 0.5730
22 K F 0.0000
23 A F 0.0000
24 L F 1.9476 mutated: KF24L
25 L F 2.1656 mutated: KF25L
26 L F 2.7938 mutated: DF26L
27 L F 1.3870
28 S F 0.0000
29 F F 0.0000
30 A F -1.5493
31 E F -2.1418
32 I F 0.0000
33 A F 0.0000
34 D F -2.7034
35 G F -1.5669
36 T F -1.6130
37 G F -0.9322
38 L F -0.5227
39 A F -1.0931
40 E F -1.9132
41 A F 0.0000
42 F F 0.0000
43 V F 0.0000
44 T F 0.0000
45 A F 0.0000
46 A F 0.0000
47 L F 0.0000
48 L F 0.0000
49 G F 0.0000
50 Q F 0.0000
51 Q F 0.0000
52 A F -0.3953
53 L F 0.0000
54 P F -1.1279
55 A F -1.3630
56 D F -2.3479
57 A F 0.0000
58 A F 0.0000
59 R F -2.8951
60 L F -1.4305
61 V F 0.0000
62 G F 0.0000
63 A F -1.3663
64 K F -1.1461
65 L F 0.0000
66 D F -2.4805
67 L F -2.4982
68 D F -3.6929
69 E F -3.7102
70 D F -2.7652
71 S F -2.2573
72 I F 0.0000
73 L F -1.1347
74 L F -0.3403
75 L F 0.0000
76 Q F -0.5695
77 M F 0.0000
78 I F 0.0000
79 P F 0.0000
80 L F -0.1228
81 R F 0.0000
82 G F 0.0000
83 C F 0.0000
84 I F 0.0000
85 D F -2.1640
86 D F -3.0306
87 R F -2.0201
88 I F 0.0000
89 P F 0.0000
90 T F 0.0000
91 D F 0.0000
92 P F 0.0000
93 T F 0.0000
94 M F 0.0000
95 Y F 0.0000
96 Q F 0.0000
97 F F 0.0000
98 Y F 0.0000
99 E F 0.0000
100 M F 0.0000
101 L F 0.0000
102 Q F 0.0000
103 V F 0.0000
104 Y F 0.0000
105 G F 0.0000
106 T F 0.0000
107 T F 0.0000
108 L F 0.0000
109 K F 0.0000
110 A F 0.0000
111 L F 0.0000
112 V F 0.0000
113 H F 0.0000
114 E F -0.2492
115 K F -1.2546
116 F F -0.7945
117 G F -0.4688
118 D F -0.6204
119 G F 0.0000
120 I F 0.0000
121 I F 0.0000
122 S F 0.0000
123 A F 0.0000
124 I F -0.5598
125 N F -1.1342
126 F F 0.0000
127 K F -1.8696
128 L F 0.0000
129 D F -2.6253
130 V F 0.0000
131 K F -2.7433
132 K F -2.3425
133 V F -1.0014
134 A F -0.9377
135 D F 0.0000
136 P F -1.3831
137 E F -2.2744
138 G F -1.6814
139 G F -1.3629
140 E F -1.5998
141 R F -1.3393
142 A F 0.0000
143 V F -1.1759
144 I F 0.0000
145 T F -0.9590
146 L F 0.0000
147 D F -1.1997
148 G F 0.0000
149 K F -1.1973
150 Y F 0.0000
151 L F 0.0000
152 P F -1.0261
153 T F -1.0991
154 K F -2.0047
155 P F -0.9300
156 F F -0.5073
1 M G 1.8632
2 I G 1.1315
3 Q G 0.0000
4 S G 0.0000
5 Q G 0.0000
6 I G -0.2230
7 N G -1.0214
8 R G -1.1790
9 N G -1.7030
10 I G -0.7908
11 R G 0.0000
12 L G -1.1053
13 D G -1.9542
14 L G 0.0000
15 A G 0.0000
16 D G 0.0000
17 A G -0.2682
18 I G 0.0000
19 L G 0.0000
20 L G 0.6862
21 S G 0.7399
22 K G 0.0000
23 A G 0.0000
24 L G 2.0570 mutated: KG24L
25 L G 2.2097 mutated: KG25L
26 L G 2.7034 mutated: DG26L
27 L G 1.3653
28 S G 0.1373
29 F G 0.0000
30 A G -1.5089
31 E G -2.1068
32 I G 0.0000
33 A G 0.0000
34 D G -2.6802
35 G G -1.5572
36 T G -1.6367
37 G G -0.9613
38 L G -0.5413
39 A G -1.0967
40 E G -1.9244
41 A G 0.0000
42 F G 0.0000
43 V G 0.0000
44 T G 0.0000
45 A G 0.0000
46 A G 0.0000
47 L G 0.0000
48 L G 0.0000
49 G G 0.0000
50 Q G 0.0000
51 Q G 0.0000
52 A G -0.3419
53 L G 0.0000
54 P G -0.9268
55 A G -1.2718
56 D G -2.2925
57 A G 0.0000
58 A G 0.0000
59 R G -2.5493
60 L G -1.3402
61 V G 0.0000
62 G G 0.0000
63 A G -1.2775
64 K G -1.0586
65 L G 0.0000
66 D G -2.4222
67 L G -2.4149
68 D G -3.3418
69 E G -3.5006
70 D G -2.4704
71 S G -2.0313
72 I G -1.9078
73 L G -0.8866
74 L G -0.1749
75 L G 0.0000
76 Q G -0.4196
77 M G 0.0000
78 I G 0.0000
79 P G 0.0000
80 L G 0.0000
81 R G 0.0000
82 G G 0.0000
83 C G 0.0000
84 I G 0.0000
85 D G -2.8238
86 D G -3.2679
87 R G -1.7878
88 I G 0.0000
89 P G 0.0000
90 T G -0.8321
91 D G 0.0000
92 P G 0.0000
93 T G 0.0000
94 M G 0.0000
95 Y G 0.0000
96 Q G 0.0000
97 F G 0.0000
98 Y G 0.0000
99 E G 0.0000
100 M G 0.0000
101 L G 0.0000
102 Q G 0.0000
103 V G 0.0000
104 Y G 0.0000
105 G G 0.0000
106 T G 0.0000
107 T G 0.0000
108 L G 0.0000
109 K G 0.0000
110 A G 0.0000
111 L G 0.0000
112 V G 0.0000
113 H G 0.0000
114 E G -0.2158
115 K G -1.1998
116 F G -0.5090
117 G G -0.3622
118 D G -0.5060
119 G G 0.0000
120 I G 0.0000
121 I G 0.0000
122 S G 0.0000
123 A G 0.0000
124 I G -0.5961
125 N G -1.1534
126 F G 0.0000
127 K G -1.8801
128 L G 0.0000
129 D G -2.6438
130 V G 0.0000
131 K G -2.6200
132 K G -2.0065
133 V G -0.9208
134 A G -0.9628
135 D G -1.5402
136 P G -1.4867
137 E G -2.3684
138 G G -1.8212
139 G G -1.5054
140 E G -1.5952
141 R G -1.3365
142 A G 0.0000
143 V G -1.3251
144 I G 0.0000
145 T G -1.1971
146 L G 0.0000
147 D G 0.0000
148 G G 0.0000
149 K G -0.8515
150 Y G -0.4036
151 L G -0.4257
152 P G -0.6180
153 T G -0.9787
154 K G -1.9037
155 P G -0.8380
156 F G -0.1644
1 M H 1.9919
2 I H 1.3316
3 Q H 0.0000
4 S H 0.0000
5 Q H 0.0000
6 I H -0.3025
7 N H -1.1441
8 R H -1.2380
9 N H -1.7474
10 I H -0.9373
11 R H 0.0000
12 L H -1.1162
13 D H -2.0042
14 L H 0.0000
15 A H 0.0000
16 D H 0.0000
17 A H -0.2637
18 I H 0.0000
19 L H 0.0000
20 L H 0.6582
21 S H 0.6621
22 K H 0.0000
23 A H 0.0000
24 L H 1.8818 mutated: KH24L
25 L H 2.1183 mutated: KH25L
26 L H 2.7151 mutated: DH26L
27 L H 1.2168
28 S H 0.0000
29 F H 0.0000
30 A H -1.5639
31 E H -2.5882
32 I H 0.0000
33 A H 0.0000
34 D H -2.7510
35 G H -1.6381
36 T H -1.6245
37 G H -0.8805
38 L H -0.3619
39 A H -0.7197
40 E H -1.3046
41 A H 0.0000
42 F H 0.0000
43 V H 0.0000
44 T H 0.0000
45 A H 0.0000
46 A H 0.0000
47 L H 0.0000
48 L H 0.0000
49 G H 0.0000
50 Q H 0.0000
51 Q H 0.0000
52 A H -0.4008
53 L H 0.0000
54 P H -1.1262
55 A H -1.3303
56 D H -2.3310
57 A H 0.0000
58 A H 0.0000
59 R H -2.6867
60 L H -1.4669
61 V H 0.0000
62 G H 0.0000
63 A H -1.4087
64 K H -1.2864
65 L H 0.0000
66 D H -2.5206
67 L H -2.5141
68 D H -3.3733
69 E H -3.5217
70 D H -2.4000
71 S H -2.1386
72 I H 0.0000
73 L H -1.0421
74 L H 0.0000
75 L H 0.0000
76 Q H -0.5725
77 M H 0.0000
78 I H 0.0000
79 P H 0.0000
80 L H -0.0696
81 R H 0.0000
82 G H 0.0000
83 C H 0.0000
84 I H 0.0000
85 D H -2.3401
86 D H -2.2558
87 R H -1.5103
88 I H 0.0000
89 P H 0.0000
90 T H -0.5843
91 D H 0.0000
92 P H 0.0000
93 T H 0.0000
94 M H 0.0000
95 Y H 0.0000
96 Q H 0.0000
97 F H 0.0000
98 Y H 0.0000
99 E H 0.0000
100 M H 0.0000
101 L H 0.0000
102 Q H 0.0000
103 V H 0.0000
104 Y H 0.0000
105 G H 0.0000
106 T H 0.0000
107 T H 0.0000
108 L H 0.0000
109 K H 0.0000
110 A H 0.0000
111 L H 0.0000
112 V H 0.0000
113 H H 0.0000
114 E H -0.2758
115 K H -1.2375
116 F H -0.7384
117 G H -0.4173
118 D H -0.5558
119 G H 0.0000
120 I H 0.0000
121 I H 0.0000
122 S H 0.0000
123 A H -0.3207
124 I H -0.6242
125 N H -1.1972
126 F H 0.0000
127 K H -1.7095
128 L H 0.0000
129 D H -2.2450
130 V H 0.0000
131 K H -2.6487
132 K H -2.2907
133 V H -0.9871
134 A H -0.9077
135 D H 0.0000
136 P H -1.3630
137 E H -2.2525
138 G H -1.6378
139 G H -1.3284
140 E H -1.5556
141 R H -1.2555
142 A H 0.0000
143 V H -1.1456
144 I H 0.0000
145 T H -1.0137
146 L H 0.0000
147 D H 0.0000
148 G H 0.0000
149 K H -0.8858
150 Y H -0.4876
151 L H -0.4800
152 P H -0.8571
153 T H -1.0046
154 K H -1.8963
155 P H -0.8226
156 F H -0.2619
1 M I 1.8241
2 I I 1.2545
3 Q I 0.0000
4 S I 0.0000
5 Q I 0.0000
6 I I -0.2530
7 N I -1.0720
8 R I -1.1851
9 N I -1.6508
10 I I -0.7306
11 R I 0.0000
12 L I -1.0554
13 D I -1.9504
14 L I 0.0000
15 A I 0.0000
16 D I 0.0000
17 A I -0.2734
18 I I 0.0000
19 L I 0.0000
20 L I 0.7167
21 S I 0.6368
22 K I 0.0000
23 A I 0.0000
24 L I 1.8241 mutated: KI24L
25 L I 2.1476 mutated: KI25L
26 L I 2.6769 mutated: DI26L
27 L I 1.3744
28 S I 0.0000
29 F I 0.0000
30 A I -1.4958
31 E I -2.0573
32 I I 0.0000
33 A I 0.0000
34 D I -2.7269
35 G I -1.5688
36 T I -1.6037
37 G I -0.9896
38 L I -0.5946
39 A I -1.0774
40 E I -1.8242
41 A I 0.0000
42 F I 0.0000
43 V I 0.0000
44 T I 0.0000
45 A I 0.0000
46 A I 0.0000
47 L I 0.0000
48 L I 0.0000
49 G I 0.0000
50 Q I 0.0000
51 Q I 0.0000
52 A I -0.3705
53 L I 0.0000
54 P I -1.0870
55 A I -1.3191
56 D I -2.3191
57 A I 0.0000
58 A I 0.0000
59 R I -2.8469
60 L I -1.1977
61 V I 0.0000
62 G I 0.0000
63 A I -1.3300
64 K I -1.0597
65 L I 0.0000
66 D I -2.4698
67 L I -2.5107
68 D I -3.6184
69 E I -3.6160
70 D I -2.5500
71 S I -2.1229
72 I I 0.0000
73 L I -1.0447
74 L I -0.2730
75 L I 0.0000
76 Q I -0.4884
77 M I 0.0000
78 I I 0.0000
79 P I 0.0000
80 L I -0.0557
81 R I 0.0000
82 G I 0.0000
83 C I 0.0000
84 I I 0.0000
85 D I -2.4586
86 D I -2.4938
87 R I -1.4262
88 I I 0.0000
89 P I 0.0000
90 T I -0.7009
91 D I 0.0000
92 P I 0.0000
93 T I 0.0000
94 M I 0.0000
95 Y I 0.0000
96 Q I 0.0000
97 F I 0.0000
98 Y I 0.0000
99 E I 0.0000
100 M I 0.0000
101 L I 0.0000
102 Q I 0.0000
103 V I 0.0000
104 Y I 0.0000
105 G I 0.0000
106 T I 0.0000
107 T I 0.0000
108 L I 0.0000
109 K I 0.0000
110 A I 0.0000
111 L I 0.0000
112 V I 0.0000
113 H I 0.0000
114 E I -0.2345
115 K I -1.2205
116 F I -0.7596
117 G I -0.4604
118 D I -0.6352
119 G I 0.0000
120 I I 0.0000
121 I I 0.0000
122 S I 0.0000
123 A I 0.0000
124 I I -0.5519
125 N I -1.1750
126 F I 0.0000
127 K I -1.7893
128 L I 0.0000
129 D I -1.8904
130 V I 0.0000
131 K I -1.9845
132 K I -2.1482
133 V I -0.7286
134 A I -0.8800
135 D I 0.0000
136 P I -1.3633
137 E I -2.2900
138 G I -1.7106
139 G I -1.3474
140 E I -1.5715
141 R I -1.2070
142 A I 0.0000
143 V I -0.8933
144 I I 0.0000
145 T I -0.9436
146 L I 0.0000
147 D I -1.3943
148 G I 0.0000
149 K I -1.2344
150 Y I -0.7622
151 L I 0.0000
152 P I -0.9466
153 T I -1.0131
154 K I -1.8791
155 P I -0.8080
156 F I -0.2177
1 M J 1.8657
2 I J 1.1587
3 Q J 0.0000
4 S J 0.0000
5 Q J 0.0000
6 I J -0.2948
7 N J -1.1293
8 R J -1.2685
9 N J -1.8078
10 I J -1.0029
11 R J 0.0000
12 L J -1.2405
13 D J -2.0852
14 L J 0.0000
15 A J 0.0000
16 D J -0.8093
17 A J -0.3621
18 I J 0.0000
19 L J 0.0000
20 L J 0.5699
21 S J 0.5537
22 K J 0.0000
23 A J 0.0000
24 L J 1.7187 mutated: KJ24L
25 L J 1.9004 mutated: KJ25L
26 L J 2.5966 mutated: DJ26L
27 L J 1.2295
28 S J 0.0000
29 F J 0.0000
30 A J -1.5928
31 E J -2.3946
32 I J 0.0000
33 A J 0.0000
34 D J -2.7408
35 G J -1.6046
36 T J -1.6411
37 G J -0.9272
38 L J -0.4833
39 A J -0.9993
40 E J -1.7202
41 A J 0.0000
42 F J 0.0000
43 V J 0.0000
44 T J 0.0000
45 A J 0.0000
46 A J 0.0000
47 L J 0.0000
48 L J 0.0000
49 G J 0.0000
50 Q J 0.0000
51 Q J 0.0000
52 A J -0.3448
53 L J 0.0000
54 P J -1.0688
55 A J -1.2202
56 D J -2.2312
57 A J 0.0000
58 A J 0.0000
59 R J -2.3799
60 L J -1.3471
61 V J 0.0000
62 G J 0.0000
63 A J -1.2675
64 K J -1.2165
65 L J 0.0000
66 D J -2.4736
67 L J -2.4374
68 D J -3.3830
69 E J -3.4938
70 D J -2.5330
71 S J -2.0532
72 I J -1.8695
73 L J -0.8492
74 L J -0.2112
75 L J 0.0000
76 Q J -0.3991
77 M J 0.0000
78 I J 0.0000
79 P J 0.0000
80 L J 0.0000
81 R J 0.0000
82 G J 0.0000
83 C J 0.0000
84 I J 0.0000
85 D J -2.8115
86 D J -3.2081
87 R J -1.8404
88 I J 0.0000
89 P J 0.0000
90 T J -0.6993
91 D J 0.0000
92 P J 0.0000
93 T J 0.0000
94 M J 0.0000
95 Y J 0.0000
96 Q J 0.0000
97 F J 0.0000
98 Y J 0.0000
99 E J 0.0000
100 M J 0.0000
101 L J 0.0000
102 Q J 0.0000
103 V J 0.0000
104 Y J 0.0000
105 G J 0.0000
106 T J 0.0000
107 T J 0.0000
108 L J 0.0000
109 K J 0.0000
110 A J 0.0000
111 L J 0.0000
112 V J 0.0000
113 H J 0.0000
114 E J -0.2753
115 K J -1.2292
116 F J -0.8120
117 G J -0.4422
118 D J -0.5915
119 G J 0.0000
120 I J 0.0000
121 I J 0.0000
122 S J 0.0000
123 A J -0.3222
124 I J -0.5906
125 N J -1.2129
126 F J 0.0000
127 K J -1.8508
128 L J 0.0000
129 D J -2.5990
130 V J 0.0000
131 K J -2.6554
132 K J -2.1485
133 V J -0.9165
134 A J -0.9578
135 D J 0.0000
136 P J -1.4174
137 E J -2.3361
138 G J -1.8293
139 G J -1.4606
140 E J -1.6553
141 R J -1.4231
142 A J 0.0000
143 V J -1.3203
144 I J 0.0000
145 T J -1.1447
146 L J 0.0000
147 D J -1.1406
148 G J 0.0000
149 K J -1.0022
150 Y J 0.0000
151 L J -0.6084
152 P J -0.9506
153 T J -1.0869
154 K J -1.9466
155 P J -0.8751
156 F J -0.3422

 

Laboratory of Theory of Biopolymers 2015