Project name: 15%_arg_2osl

Chain sequence(s)	A: QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8186
• Maximal score value: 1.6421
• Average score: -0.6591
• Total score value: -286.6903

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.0761
2	I	A	-0.0581
3	V	A	1.0115
4	L	A	0.0000
5	S	A	-0.6183
6	Q	A	-0.7346
7	S	A	-0.4031
8	P	A	0.2668
9	A	A	0.5669
10	I	A	1.6421
11	L	A	0.7373
12	S	A	-0.2495
13	A	A	0.0000
14	S	A	-2.0127
15	P	A	-2.0800
16	G	A	-2.2516
17	E	A	-3.0729
18	K	A	-2.9705
19	V	A	-1.2827
20	T	A	-0.3484
21	M	A	0.0000
22	T	A	-0.7102
23	C	A	0.0000
24	R	A	-1.9300
25	A	A	0.0000
26	S	A	-0.3567
27	S	A	-0.4974
28	S	A	-0.6532
29	V	A	0.0000
30	S	A	-0.1257
31	Y	A	0.2799
32	I	A	0.0000
33	H	A	0.0000
34	W	A	0.0000
35	F	A	0.0000
36	Q	A	0.0000
37	Q	A	-0.8344
38	K	A	0.0000
39	P	A	-0.8799
40	G	A	-0.6335
41	S	A	-0.7411
42	S	A	-0.6947
43	P	A	0.0000
44	K	A	-1.7942
45	P	A	-0.8432
46	W	A	-0.5596
47	I	A	0.0000
48	Y	A	-0.0307
49	A	A	-0.0630
50	T	A	-0.2697
51	S	A	-0.6362
52	N	A	-1.0321
53	L	A	0.0194
54	A	A	0.0000
55	S	A	-0.7054
56	G	A	-0.3289
57	V	A	0.0000
58	P	A	0.5249
59	V	A	1.2823
60	R	A	-0.5384
61	F	A	0.0000
62	S	A	-0.1058
63	G	A	0.0000
64	S	A	-0.5962
65	G	A	-0.7702
66	S	A	-0.7172
67	G	A	-0.7272
68	T	A	-1.0203
69	S	A	-1.2808
70	Y	A	0.0000
71	S	A	-0.6402
72	L	A	0.0000
73	T	A	-0.7282
74	I	A	0.0000
75	S	A	-2.1568
76	R	A	-3.2350
77	V	A	0.0000
78	E	A	-2.7946
79	A	A	0.0000
80	E	A	-2.3266
81	D	A	0.0000
82	A	A	-1.4649
83	A	A	0.0000
84	T	A	0.0000
85	Y	A	0.0000
86	Y	A	-0.2790
87	C	A	0.0000
88	Q	A	0.0000
89	Q	A	0.0000
90	W	A	-0.0465
91	T	A	-0.2532
92	S	A	-0.9731
93	N	A	-1.7157
94	P	A	-1.5581
95	P	A	0.0000
96	T	A	-0.0818
97	F	A	0.2609
98	G	A	0.0000
99	G	A	-0.7118
100	G	A	0.0000
101	T	A	0.0000
102	K	A	-0.2950
103	L	A	0.0000
104	E	A	-0.8449
105	I	A	0.0000
106	K	A	-2.0386
107	R	A	-1.3121
108	T	A	-0.2199
109	V	A	0.3905
110	A	A	0.0335
111	A	A	-0.1241
112	P	A	0.0000
113	S	A	-0.1696
114	V	A	0.0000
115	F	A	0.0744
116	I	A	0.1058
117	F	A	0.0000
118	P	A	-0.4325
119	P	A	0.0000
120	S	A	-1.5566
121	D	A	-2.8033
122	E	A	-2.7349
123	Q	A	0.0000
124	L	A	-1.5877
125	K	A	-1.9607
126	S	A	-1.3154
127	G	A	-1.0424
128	T	A	-0.8345
129	A	A	0.0000
130	S	A	0.0000
131	V	A	0.0000
132	V	A	0.0000
133	C	A	0.0000
134	L	A	0.0000
135	L	A	0.0000
136	N	A	0.0000
137	N	A	-0.7099
138	F	A	0.0000
139	Y	A	0.0000
140	P	A	-1.8567
141	R	A	-2.9639
142	E	A	-3.2461
143	A	A	-2.4427
144	K	A	-2.4949
145	V	A	0.0000
146	Q	A	-0.7264
147	W	A	0.0000
148	K	A	-0.5755
149	V	A	0.0000
150	D	A	-2.2626
151	N	A	-1.6456
152	A	A	-0.2984
153	L	A	0.6776
154	Q	A	-0.1404
155	S	A	-0.4985
156	G	A	-1.0145
157	N	A	-0.9632
158	S	A	-1.0020
159	Q	A	-1.9463
160	E	A	-2.1551
161	S	A	-1.0438
162	V	A	-0.9321
163	T	A	-1.0621
164	E	A	-2.2700
165	Q	A	-2.1033
166	D	A	-2.1447
167	S	A	-2.3219
168	K	A	-2.8533
169	D	A	-2.2630
170	S	A	0.0000
171	T	A	0.0000
172	Y	A	0.0000
173	S	A	0.0000
174	L	A	0.0000
175	S	A	0.0000
176	S	A	0.0000
177	T	A	-0.2340
178	L	A	0.6452
179	T	A	0.3077
180	L	A	-0.1648
181	S	A	-1.1586
182	K	A	-2.0866
183	A	A	-1.9254
184	D	A	-2.7122
185	Y	A	0.0000
186	E	A	-3.8186
187	K	A	-3.8131
188	H	A	-3.2916
189	K	A	-3.5207
190	V	A	0.0000
191	Y	A	0.0000
192	A	A	0.0000
193	C	A	0.0000
194	E	A	-0.8423
195	V	A	0.0000
196	T	A	-1.3307
197	H	A	0.0000
198	Q	A	-1.4242
199	G	A	-0.4562
200	L	A	-0.2459
201	S	A	-0.4502
202	S	A	-0.4504
203	P	A	-0.4029
204	V	A	0.0111
205	T	A	-0.3472
206	K	A	-0.4378
207	S	A	-0.5791
208	F	A	-1.0948
209	N	A	-2.2253
210	R	A	-2.6244
211	G	A	-2.3351
212	E	A	-2.5319
1	Q	A	-0.9165
2	V	A	0.1315
3	Q	A	-1.0284
4	L	A	0.0000
5	Q	A	-1.9399
6	Q	A	-1.1208
7	P	A	-0.8582
8	G	A	-0.9743
9	A	A	-0.7243
10	E	A	-0.8513
11	L	A	-0.2855
12	V	A	0.0000
13	K	A	-1.8534
14	P	A	-1.2998
15	G	A	-1.1931
16	A	A	-0.9842
17	S	A	-1.0801
18	V	A	-1.0878
19	K	A	-1.7660
20	M	A	0.0000
21	S	A	-0.9046
22	C	A	0.0000
23	K	A	-1.6707
24	A	A	0.0000
25	S	A	-0.8619
26	G	A	-0.4990
27	Y	A	-0.0847
28	T	A	-0.1265
29	F	A	0.0000
30	T	A	-0.6251
31	S	A	-0.1777
32	Y	A	0.3249
33	N	A	-0.1461
34	M	A	0.0000
35	H	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	K	A	0.0000
39	Q	A	0.0000
40	T	A	-1.0657
41	P	A	-1.0328
42	G	A	-1.5656
43	R	A	-2.3608
44	G	A	-1.3791
45	L	A	0.0000
46	E	A	-1.0720
47	W	A	0.0000
48	I	A	0.0000
49	G	A	0.0000
50	A	A	0.0000
51	I	A	0.0000
52	Y	A	-0.7168
53	P	A	0.0000
54	G	A	-1.3051
55	N	A	-2.2066
56	G	A	-2.1092
57	D	A	-2.3868
58	T	A	-1.1735
59	S	A	-0.9375
60	Y	A	-1.2058
61	N	A	-2.1427
62	Q	A	-2.8156
63	K	A	-2.8305
64	F	A	-2.1290
65	K	A	-2.7509
66	G	A	-1.9151
67	K	A	-1.5269
68	A	A	0.0000
69	T	A	-0.7543
70	L	A	0.0000
71	T	A	-0.5677
72	A	A	-1.2275
73	D	A	-1.6915
74	K	A	-2.3903
75	S	A	-1.3326
76	S	A	-1.1680
77	S	A	-1.2886
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.4577
81	M	A	0.0000
82	Q	A	-1.1271
83	L	A	0.0000
84	S	A	-0.8660
85	S	A	-0.8651
86	L	A	0.0000
87	T	A	-1.2013
88	S	A	-1.3645
89	E	A	-1.9351
90	D	A	0.0000
91	S	A	-0.5462
92	A	A	0.0000
93	V	A	0.2951
94	Y	A	0.0000
95	Y	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	S	A	0.0000
100	T	A	0.6748
101	Y	A	1.3188
102	Y	A	1.4773
103	G	A	0.3699
104	G	A	0.3353
105	D	A	0.6168
106	W	A	0.8642
107	Y	A	0.5770
108	F	A	0.0000
109	N	A	-0.3785
110	V	A	-0.1932
111	W	A	0.0000
112	G	A	0.0000
113	A	A	-0.4871
114	G	A	-0.3681
115	T	A	0.0000
116	T	A	-0.1968
117	V	A	0.0000
118	T	A	-0.2820
119	V	A	-0.7444
120	S	A	-0.5708
121	A	A	-0.5859
122	A	A	-0.4256
123	S	A	-0.6043
124	T	A	-0.6687
125	K	A	-1.1787
126	G	A	-1.3108
127	P	A	-0.5699
128	S	A	-0.4199
129	V	A	0.0000
130	F	A	0.0000
131	P	A	-1.0728
132	L	A	0.0000
133	A	A	-1.1520
134	P	A	0.0000
135	S	A	-1.4025
136	S	A	-1.2624
137	K	A	-1.3273
138	S	A	-0.8254
139	T	A	-0.7366
140	S	A	-0.7622
141	G	A	-0.8883
142	G	A	-0.8126
143	T	A	-0.5854
144	A	A	0.0000
145	A	A	0.0000
146	L	A	0.0000
147	G	A	0.0000
148	C	A	0.0000
149	L	A	0.0000
150	V	A	0.0000
151	K	A	0.0000
152	D	A	-0.4171
153	Y	A	0.0000
154	F	A	0.0000
155	P	A	0.0000
156	E	A	-0.4795
157	P	A	-0.7272
158	V	A	-0.3409
159	T	A	-0.5199
160	V	A	0.0658
161	S	A	-0.3654
162	W	A	0.0000
163	N	A	-0.8368
164	S	A	-0.7032
165	G	A	-0.5889
166	A	A	-0.2708
167	L	A	-0.0301
168	T	A	-0.1625
169	S	A	-0.1591
170	G	A	-0.1563
171	V	A	0.1862
172	H	A	-0.0288
173	T	A	0.0689
174	F	A	0.0000
175	P	A	-0.3326
176	A	A	0.4522
177	V	A	0.4822
178	L	A	1.3042
179	Q	A	0.1795
180	S	A	-0.1221
181	S	A	-0.3138
182	G	A	-0.1670
183	L	A	0.0793
184	Y	A	0.4405
185	S	A	0.4292
186	L	A	0.4053
187	S	A	0.0000
188	S	A	0.0000
189	V	A	0.0000
190	V	A	0.0000
191	T	A	-0.1394
192	V	A	0.0000
193	P	A	-0.4909
194	S	A	-0.5642
195	S	A	-0.6314
196	S	A	-0.6238
197	L	A	-0.6389
198	G	A	-0.7245
199	T	A	-0.8222
200	Q	A	-1.2807
201	T	A	-1.1273
202	Y	A	0.0000
203	I	A	-1.0606
204	C	A	0.0000
205	N	A	-1.5450
206	V	A	0.0000
207	N	A	-1.8869
208	H	A	0.0000
209	K	A	-2.8102
210	P	A	-1.5714
211	S	A	-1.8467
212	N	A	-2.6050
213	T	A	-2.0547
214	K	A	-2.7273
215	V	A	-1.5540
216	D	A	-2.4882
217	K	A	-1.7485
218	K	A	-2.0604
219	V	A	0.0000
220	E	A	-2.5815
221	P	A	-2.1335
222	K	A	-2.4954
223	S	A	-1.4758