Chain sequence(s) |
A: ILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICCIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEEL E: SDILFPA |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
4 | I | A | 2.0908 | |
5 | L | A | 1.2144 | |
6 | P | A | 0.0000 | |
7 | I | A | 0.0000 | |
8 | R | A | -1.4964 | |
9 | F | A | -0.6634 | |
10 | Q | A | -1.8010 | |
11 | E | A | -1.8229 | |
12 | H | A | -1.3138 | |
13 | L | A | -1.0303 | |
14 | Q | A | -1.3291 | |
15 | L | A | 0.0000 | |
16 | Q | A | -1.9402 | |
17 | N | A | -1.8148 | |
18 | L | A | -1.2261 | |
19 | G | A | -1.3220 | |
20 | I | A | 0.0000 | |
21 | N | A | -2.0478 | |
22 | P | A | -1.4779 | |
23 | A | A | -0.7749 | |
24 | N | A | -0.8818 | |
25 | I | A | 0.0000 | |
26 | G | A | -0.1103 | |
27 | F | A | 0.6030 | |
28 | S | A | -0.0226 | |
29 | T | A | -0.1842 | |
30 | L | A | 0.0000 | |
31 | T | A | 0.0244 | |
32 | M | A | 0.0000 | |
33 | E | A | -0.4625 | |
34 | S | A | -0.7521 | |
35 | D | A | -1.4620 | |
36 | K | A | -1.8219 | |
37 | F | A | 0.0000 | |
38 | I | A | 0.0000 | |
39 | C | A | 0.0000 | |
40 | I | A | 0.0000 | |
41 | R | A | -0.8963 | |
42 | E | A | 0.0000 | |
43 | K | A | -2.2181 | |
44 | V | A | -0.8027 | |
45 | G | A | -1.4977 | |
46 | E | A | -2.4811 | |
47 | Q | A | -1.8711 | |
48 | A | A | -1.5771 | |
49 | Q | A | -0.9639 | |
50 | V | A | 0.0000 | |
51 | V | A | 0.0000 | |
52 | I | A | 0.0000 | |
53 | I | A | 0.0000 | |
54 | D | A | -1.8490 | |
55 | M | A | -1.8470 | |
56 | N | A | -2.5943 | |
57 | D | A | -3.0325 | |
58 | P | A | -1.8475 | |
59 | S | A | -1.6434 | |
60 | N | A | -2.0498 | |
61 | P | A | -1.0671 | |
62 | I | A | -0.3179 | |
63 | R | A | -0.7566 | |
64 | R | A | -0.3524 | |
65 | P | A | -0.4171 | |
66 | I | A | 0.0000 | |
67 | S | A | -0.6763 | |
68 | A | A | 0.0000 | |
69 | D | A | -1.2322 | |
70 | S | A | -0.6610 | |
71 | A | A | 0.0000 | |
72 | I | A | 0.0000 | |
73 | M | A | 0.0000 | |
74 | N | A | 0.0000 | |
75 | P | A | -0.0817 | |
76 | A | A | -0.0947 | |
77 | S | A | -0.4795 | |
78 | K | A | -0.8907 | |
79 | V | A | 0.0000 | |
80 | I | A | 0.0000 | |
81 | A | A | 0.0000 | |
82 | L | A | 0.0000 | |
83 | K | A | 0.0000 | |
84 | A | A | -1.1754 | |
85 | G | A | -1.8538 | |
86 | K | A | -2.5649 | |
87 | T | A | -1.4042 | |
88 | L | A | 0.0000 | |
89 | Q | A | 0.0000 | |
90 | I | A | 0.0000 | |
91 | F | A | 0.0000 | |
92 | N | A | -1.2871 | |
93 | I | A | 0.0000 | |
94 | E | A | -2.0250 | |
95 | M | A | -0.9431 | |
96 | K | A | -2.0564 | |
97 | S | A | -1.6262 | |
98 | K | A | -1.6666 | |
99 | M | A | -0.5893 | |
100 | K | A | -1.0554 | |
101 | A | A | -0.6142 | |
102 | H | A | -0.7830 | |
103 | T | A | -1.1486 | |
104 | M | A | 0.0000 | |
105 | T | A | -1.1979 | |
106 | D | A | -2.4675 | |
107 | D | A | -3.1504 | |
108 | V | A | 0.0000 | |
109 | T | A | -1.0714 | |
110 | F | A | -0.5566 | |
111 | W | A | 0.0000 | |
112 | K | A | -0.3480 | |
113 | W | A | 0.0000 | |
114 | I | A | 0.2729 | |
115 | S | A | 0.5297 | |
116 | L | A | 1.2880 | |
117 | N | A | -0.1027 | |
118 | T | A | 0.0000 | |
119 | V | A | 0.0000 | |
120 | A | A | 0.0000 | |
121 | L | A | 0.0000 | |
122 | V | A | 0.0000 | |
123 | T | A | 0.0000 | |
124 | D | A | -3.1257 | |
125 | N | A | -3.0619 | |
126 | A | A | 0.0000 | |
127 | V | A | 0.0000 | |
128 | Y | A | -0.1815 | |
129 | H | A | 0.0000 | |
130 | W | A | 0.0000 | |
131 | S | A | -0.9438 | |
132 | M | A | -1.3837 | |
133 | E | A | -2.7587 | |
134 | G | A | -2.4147 | |
135 | E | A | -2.8073 | |
136 | S | A | -1.9766 | |
137 | Q | A | -1.7496 | |
138 | P | A | -0.1590 | |
139 | V | A | 0.6570 | |
140 | K | A | -0.8561 | |
141 | M | A | -0.5469 | |
142 | F | A | 0.0000 | |
143 | D | A | -2.7722 | |
144 | R | A | -2.0809 | |
145 | H | A | -1.4830 | |
146 | S | A | -0.9690 | |
147 | S | A | -0.7422 | |
148 | L | A | 0.0000 | |
149 | A | A | -1.0066 | |
150 | G | A | -0.9289 | |
151 | C | A | -0.8148 | |
152 | Q | A | -1.1339 | |
153 | I | A | 0.0000 | |
154 | I | A | 0.0000 | |
155 | N | A | -0.6236 | |
156 | Y | A | 0.0000 | |
157 | R | A | -0.4118 | |
158 | T | A | -0.5856 | |
159 | D | A | 0.0000 | |
160 | A | A | -1.0033 | |
161 | K | A | -2.0283 | |
162 | Q | A | -1.3552 | |
163 | K | A | -2.0595 | |
164 | W | A | -1.0460 | |
165 | L | A | 0.0000 | |
166 | L | A | 0.0000 | |
167 | L | A | 0.0000 | |
168 | T | A | 0.0000 | |
169 | G | A | 0.0000 | |
170 | I | A | -0.3014 | |
171 | S | A | -0.5259 | |
172 | A | A | -1.1901 | |
173 | Q | A | -2.0821 | |
174 | Q | A | -2.4045 | |
175 | N | A | -2.4477 | |
176 | R | A | -2.0022 | |
177 | V | A | -0.6276 | |
178 | V | A | -0.6153 | |
179 | G | A | 0.0000 | |
180 | A | A | -0.3941 | |
181 | M | A | 0.0000 | |
182 | Q | A | 0.0000 | |
183 | L | A | 0.0000 | |
184 | Y | A | 0.0000 | |
185 | S | A | 0.0000 | |
186 | V | A | -1.6195 | |
187 | D | A | -3.0031 | |
188 | R | A | -3.1403 | |
189 | K | A | -2.4567 | |
190 | V | A | -0.7319 | |
191 | S | A | -0.9772 | |
192 | Q | A | -1.0266 | |
193 | P | A | -1.0197 | |
194 | I | A | -0.7218 | |
195 | E | A | -1.0396 | |
196 | G | A | 0.0000 | |
197 | H | A | 0.0000 | |
198 | A | A | 0.0000 | |
199 | A | A | 0.0000 | |
200 | S | A | 0.0000 | |
201 | F | A | 0.0000 | |
202 | A | A | 0.0000 | |
203 | Q | A | -1.4915 | |
204 | F | A | 0.0000 | |
205 | K | A | -3.5170 | |
206 | M | A | 0.0000 | |
207 | E | A | -2.9867 | |
208 | G | A | -2.1277 | |
209 | N | A | -2.5485 | |
210 | A | A | -2.0522 | |
211 | E | A | -3.2576 | |
212 | E | A | -3.2070 | |
213 | S | A | 0.0000 | |
214 | T | A | 0.0000 | |
215 | L | A | 0.0000 | |
216 | F | A | 0.0000 | |
217 | C | A | 0.0000 | |
218 | F | A | 0.0000 | |
219 | A | A | 0.0000 | |
220 | V | A | 0.0000 | |
221 | R | A | -1.0859 | |
222 | G | A | -1.1543 | |
223 | Q | A | -1.3320 | |
224 | A | A | -1.0284 | |
225 | G | A | -0.9221 | |
226 | G | A | -0.9266 | |
227 | K | A | -1.3572 | |
228 | L | A | 0.0000 | |
229 | H | A | -0.7748 | |
230 | I | A | 0.0000 | |
231 | I | A | -0.6560 | |
232 | E | A | -0.6707 | |
233 | V | A | 0.0000 | |
234 | G | A | -0.9589 | |
235 | T | A | -0.3922 | |
236 | P | A | -1.1422 | |
237 | P | A | -1.1902 | |
238 | T | A | -0.8133 | |
239 | G | A | -1.2129 | |
240 | N | A | -2.1482 | |
241 | Q | A | -2.0500 | |
242 | P | A | -1.3042 | |
243 | F | A | 0.0000 | |
244 | P | A | -1.3251 | |
245 | K | A | -1.9368 | |
246 | K | A | -1.1046 | |
247 | A | A | -0.9031 | |
248 | V | A | -0.6724 | |
249 | D | A | -1.5921 | |
250 | V | A | 0.0000 | |
251 | F | A | 0.8748 | |
252 | F | A | -0.1298 | |
253 | P | A | -0.5328 | |
254 | P | A | -1.4424 | |
255 | E | A | -2.4719 | |
256 | A | A | 0.0000 | |
257 | Q | A | -2.4524 | |
258 | N | A | -2.2918 | |
259 | D | A | 0.0000 | |
260 | F | A | 0.0000 | |
261 | P | A | 0.0000 | |
262 | V | A | 0.2474 | |
263 | A | A | 0.0740 | |
264 | M | A | 0.0000 | |
265 | Q | A | 0.0000 | |
266 | I | A | -0.5331 | |
267 | S | A | 0.0000 | |
268 | E | A | -2.8126 | |
269 | K | A | -2.7552 | |
270 | H | A | 0.0000 | |
271 | D | A | 0.0000 | |
272 | V | A | 0.0000 | |
273 | V | A | 0.0000 | |
274 | F | A | 0.0000 | |
275 | L | A | 0.0000 | |
276 | I | A | 0.0000 | |
277 | T | A | 0.0000 | |
278 | K | A | -0.2334 | |
279 | Y | A | -0.1417 | |
280 | G | A | 0.0000 | |
281 | Y | A | -0.4231 | |
282 | I | A | 0.0000 | |
283 | H | A | 0.0000 | |
284 | L | A | 0.0000 | |
285 | Y | A | 0.0000 | |
286 | D | A | 0.0000 | |
287 | L | A | 0.0000 | |
288 | E | A | -0.7126 | |
289 | T | A | -0.3975 | |
290 | G | A | 0.0000 | |
291 | T | A | -0.1739 | |
292 | C | A | 0.2947 | |
293 | I | A | 0.0000 | |
294 | Y | A | 0.0000 | |
295 | M | A | -0.0454 | |
296 | N | A | -1.2891 | |
297 | R | A | -1.2607 | |
298 | I | A | -0.5128 | |
299 | S | A | 0.0000 | |
300 | G | A | -1.0242 | |
301 | E | A | -1.3554 | |
302 | T | A | -0.7142 | |
303 | I | A | 0.0000 | |
304 | F | A | 0.0000 | |
305 | V | A | 0.2245 | |
306 | T | A | -0.0294 | |
307 | A | A | 0.0000 | |
308 | P | A | -0.9451 | |
309 | H | A | -1.3432 | |
310 | E | A | -2.1070 | |
311 | A | A | -0.9679 | |
312 | T | A | -1.1791 | |
313 | A | A | -1.4926 | |
314 | G | A | 0.0000 | |
315 | I | A | 0.0000 | |
316 | I | A | 0.0000 | |
317 | G | A | 0.0000 | |
318 | V | A | 0.0000 | |
319 | N | A | 0.0000 | |
320 | R | A | -1.5769 | |
321 | K | A | -2.2423 | |
322 | G | A | 0.0000 | |
323 | Q | A | -1.5859 | |
324 | V | A | 0.0000 | |
325 | L | A | 0.0000 | |
326 | S | A | 0.0000 | |
327 | V | A | 0.0000 | |
328 | C | A | 0.0000 | |
329 | V | A | 0.0000 | |
330 | E | A | 0.0000 | |
331 | E | A | -2.5151 | |
332 | E | A | -2.2383 | |
333 | N | A | -1.0622 | |
334 | I | A | 0.0000 | |
335 | I | A | 0.0000 | |
336 | P | A | -0.5419 | |
337 | Y | A | 0.3358 | |
338 | I | A | 0.0000 | |
339 | T | A | 0.0000 | |
340 | N | A | -0.6486 | |
341 | V | A | 0.9979 | |
342 | L | A | 0.1552 | |
343 | Q | A | -1.1896 | |
344 | N | A | -1.1405 | |
345 | P | A | -1.2058 | |
346 | D | A | -1.7572 | |
347 | L | A | 0.0000 | |
348 | A | A | 0.0000 | |
349 | L | A | 0.1471 | |
350 | R | A | -0.1697 | |
351 | M | A | 0.0000 | |
352 | A | A | 0.0000 | |
353 | V | A | 1.2396 | |
354 | R | A | -0.2151 | |
355 | N | A | -1.1252 | |
356 | N | A | -1.1524 | |
357 | L | A | 0.0000 | |
358 | A | A | -1.2439 | |
359 | G | A | -1.4288 | |
360 | A | A | -0.8729 | |
361 | E | A | -2.2723 | |
362 | E | A | -1.9043 | |
363 | L | A | -0.3376 | |
1 | S | E | -0.7292 | |
2 | D | E | -1.3838 | |
3 | I | E | 0.0000 | |
4 | L | E | 0.0000 | |
5 | F | E | 0.0092 | |
6 | P | E | -0.2816 | |
7 | A | E | -0.0728 |