Project name: 4v0v_modified_chains-AB.pdb_stat_DIBS

Chain sequence(s)	A: MLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSRREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGEENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE; B: KKVTFLEEVTEYYISGDEDR
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8546
• Maximal score value: 1.2591
• Average score: -0.9126
• Total score value: -287.4581

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
6	M	A	0.7728
7	L	A	-0.4061
8	N	A	-1.4652
9	I	A	-1.4308
10	D	A	-2.5355
11	S	A	-1.6974
12	I	A	0.0000
13	I	A	-1.5924
14	Q	A	-2.2668
15	R	A	-2.1370
16	L	A	0.0000
17	L	A	-1.6319
18	E	A	-2.6767
19	V	A	0.0000
20	R	A	-2.5190
21	G	A	-1.9353
22	S	A	-2.3058
23	K	A	-2.5816
24	P	A	-2.4642
25	G	A	-2.5235
26	K	A	-2.8839
27	N	A	-2.2540
28	V	A	0.0000
29	Q	A	-2.0485
30	L	A	0.0000
31	Q	A	-2.2759
32	E	A	-2.0856
33	N	A	-2.2217
34	E	A	-1.5433
35	I	A	0.0000
36	R	A	-1.4226
37	G	A	-0.7108
38	L	A	0.0000
39	C	A	0.0000
40	L	A	-0.1252
41	K	A	-0.9182
42	S	A	0.0000
43	R	A	-1.3207
44	E	A	-1.7885
45	I	A	-0.8023
46	F	A	0.0000
47	L	A	-0.1168
48	S	A	-0.4585
49	Q	A	-0.7071
50	P	A	-0.6002
51	I	A	0.0000
52	L	A	0.0000
53	L	A	0.0000
54	E	A	-2.5464
55	L	A	0.0000
56	E	A	-3.0450
57	A	A	-1.9748
58	P	A	-1.7082
59	L	A	0.0000
60	K	A	-0.5143
61	I	A	0.0000
62	C	A	0.0000
63	G	A	0.0000
64	D	A	0.0000
65	I	A	0.0000
66	H	A	0.0000
67	G	A	0.0000
68	Q	A	0.0000
69	Y	A	0.0000
70	Y	A	0.0000
71	D	A	0.0000
72	L	A	0.0000
73	L	A	0.0000
74	R	A	-1.0142
75	L	A	0.0000
76	F	A	0.0000
77	E	A	-1.6599
78	Y	A	-0.4384
79	G	A	-0.7428
80	G	A	-1.1082
81	F	A	-0.8313
82	P	A	0.0000
83	P	A	-1.4935
84	E	A	-2.0129
85	S	A	-1.2889
86	N	A	-1.4653
87	Y	A	0.0000
88	L	A	0.0000
89	F	A	0.0000
90	L	A	0.0000
91	G	A	0.0000
92	D	A	0.0000
93	Y	A	0.0000
94	V	A	0.0000
95	D	A	0.0000
96	R	A	-1.6066
97	G	A	-1.6028
98	K	A	-2.4955
99	Q	A	0.0000
100	S	A	0.0000
101	L	A	0.0000
102	E	A	0.0000
103	T	A	0.0000
104	I	A	0.0000
105	C	A	0.0000
106	L	A	0.0000
107	L	A	0.0000
108	L	A	0.0000
109	A	A	0.0000
110	Y	A	0.0000
111	K	A	0.0000
112	I	A	0.0000
113	K	A	-1.4361
114	Y	A	-0.9972
115	P	A	-1.1666
116	E	A	-2.1936
117	N	A	-1.9977
118	F	A	0.0000
119	F	A	-0.3016
120	L	A	0.0000
121	L	A	0.0000
122	R	A	0.0000
123	G	A	0.0000
124	N	A	0.0000
125	H	A	-0.0229
126	E	A	0.0000
127	C	A	-0.7566
128	A	A	-0.9056
129	S	A	-0.2139
130	I	A	0.4823
131	N	A	0.0000
132	R	A	-0.5484
133	I	A	1.2591
134	Y	A	0.5586
135	G	A	-0.6634
136	F	A	0.0000
137	Y	A	-1.1890
138	D	A	-1.8516
139	E	A	-2.0568
140	C	A	0.0000
141	K	A	-2.5399
142	R	A	-2.8229
143	R	A	-1.9775
144	Y	A	-1.6852
145	N	A	-1.8823
146	I	A	-1.5382
147	K	A	-2.3120
148	L	A	0.0000
149	W	A	0.0000
150	K	A	-2.5986
151	T	A	-1.6917
152	F	A	0.0000
153	T	A	-2.0669
154	D	A	-2.3174
155	C	A	0.0000
156	F	A	0.0000
157	N	A	-1.3228
158	C	A	0.0000
159	L	A	0.0000
160	P	A	0.0000
161	I	A	0.0000
162	A	A	0.0000
163	A	A	0.0000
164	I	A	-1.3153
165	V	A	0.0000
166	D	A	-2.8659
167	E	A	-3.1929
168	K	A	-2.3427
169	I	A	0.0000
170	F	A	0.0000
171	C	A	0.0000
172	C	A	0.0000
173	H	A	0.0000
174	G	A	0.0000
175	G	A	0.0000
176	L	A	0.0000
177	S	A	0.0000
178	P	A	-1.1046
179	D	A	-2.1823
180	L	A	0.0000
181	Q	A	-2.2153
182	S	A	-1.8379
183	M	A	-1.6108
184	E	A	-2.8773
185	Q	A	-2.3524
186	I	A	0.0000
187	R	A	-2.4018
188	R	A	-2.4491
189	I	A	-0.7072
190	M	A	0.4759
191	R	A	-0.0712
192	P	A	-0.6580
193	T	A	-0.9968
194	D	A	-2.2611
195	V	A	-1.3595
196	P	A	-1.7610
197	D	A	-2.5478
198	Q	A	-2.0138
199	G	A	-1.4217
200	L	A	-0.8448
201	L	A	0.0000
202	C	A	0.0000
203	D	A	0.0000
204	L	A	0.0000
205	L	A	0.0000
206	W	A	-0.0676
207	S	A	0.0000
208	D	A	0.0000
209	P	A	-0.9107
210	D	A	-1.8541
211	K	A	-2.6385
212	D	A	-2.4014
213	V	A	-0.9345
214	L	A	0.5975
215	G	A	0.2455
216	W	A	0.3039
217	G	A	-0.9444
218	E	A	-2.2660
219	N	A	0.0000
220	D	A	-2.7954
221	R	A	-2.2090
222	G	A	-1.6898
223	V	A	-1.3095
224	S	A	-1.1786
225	F	A	-1.0098
226	T	A	-1.0745
227	F	A	0.0000
228	G	A	0.0000
229	A	A	-1.7585
230	E	A	-1.8530
231	V	A	-1.0245
232	V	A	0.0000
233	A	A	-2.2216
234	K	A	-3.1309
235	F	A	0.0000
236	L	A	0.0000
237	H	A	-3.1496
238	K	A	-3.4237
239	H	A	-2.8747
240	D	A	-3.3789
241	L	A	0.0000
242	D	A	-2.3446
243	L	A	0.0000
244	I	A	0.0000
245	C	A	0.0000
246	R	A	0.0000
247	A	A	0.0000
248	H	A	0.0000
249	Q	A	-0.4287
250	V	A	-0.4353
251	V	A	0.0000
252	E	A	-3.0270
253	D	A	-3.3500
254	G	A	0.0000
255	Y	A	-1.3160
256	E	A	-2.0377
257	F	A	-1.2874
258	F	A	0.0000
259	A	A	0.0000
260	K	A	-2.5574
261	R	A	-2.8334
262	Q	A	-1.7034
263	L	A	0.0000
264	V	A	0.0000
265	T	A	0.0000
266	L	A	0.0000
267	F	A	0.0000
268	S	A	0.0000
269	A	A	0.0000
270	P	A	0.0000
271	N	A	0.0000
272	Y	A	-0.6604
273	C	A	-1.4299
274	G	A	-2.3947
275	E	A	-2.1208
276	F	A	-0.9259
277	D	A	-2.4987
278	N	A	0.0000
279	A	A	0.0000
280	G	A	0.0000
281	A	A	0.0000
282	M	A	0.0000
283	M	A	0.0000
284	S	A	-0.5189
285	V	A	0.0000
286	D	A	-1.7603
287	E	A	-2.7163
288	T	A	-1.8824
289	L	A	0.0000
290	M	A	-0.5776
291	C	A	0.0000
292	S	A	-0.4349
293	F	A	0.0000
294	Q	A	-0.8892
295	I	A	0.0000
296	L	A	0.0000
297	K	A	-1.2665
298	P	A	-1.2429
299	A	A	-1.5403
300	E	A	-2.7796
639	K	B	-3.1107
640	K	B	-2.7126
641	V	B	0.0000
642	T	B	-0.8207
643	F	B	-0.2762
644	L	B	-0.5685
645	E	B	-2.2116
646	E	B	-2.4712
647	V	B	-1.2610
648	T	B	-1.3273
649	E	B	-1.8475
650	Y	B	-0.0887
651	Y	B	0.5249
652	I	B	0.0000
653	S	B	-1.0364
654	G	B	-2.1606
655	D	B	0.0000
656	E	B	-3.7475
657	D	B	-3.8546
658	R	B	-3.6745