Chain sequence(s) |
A: MLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSRREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGEENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE B: KKVTFLEEVTEYYISGDEDR |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
6 | M | A | 0.7728 | |
7 | L | A | -0.4061 | |
8 | N | A | -1.4652 | |
9 | I | A | -1.4308 | |
10 | D | A | -2.5355 | |
11 | S | A | -1.6974 | |
12 | I | A | 0.0000 | |
13 | I | A | -1.5924 | |
14 | Q | A | -2.2668 | |
15 | R | A | -2.1370 | |
16 | L | A | 0.0000 | |
17 | L | A | -1.6319 | |
18 | E | A | -2.6767 | |
19 | V | A | 0.0000 | |
20 | R | A | -2.5190 | |
21 | G | A | -1.9353 | |
22 | S | A | -2.3058 | |
23 | K | A | -2.5816 | |
24 | P | A | -2.4642 | |
25 | G | A | -2.5235 | |
26 | K | A | -2.8839 | |
27 | N | A | -2.2540 | |
28 | V | A | 0.0000 | |
29 | Q | A | -2.0485 | |
30 | L | A | 0.0000 | |
31 | Q | A | -2.2759 | |
32 | E | A | -2.0856 | |
33 | N | A | -2.2217 | |
34 | E | A | -1.5433 | |
35 | I | A | 0.0000 | |
36 | R | A | -1.4226 | |
37 | G | A | -0.7108 | |
38 | L | A | 0.0000 | |
39 | C | A | 0.0000 | |
40 | L | A | -0.1252 | |
41 | K | A | -0.9182 | |
42 | S | A | 0.0000 | |
43 | R | A | -1.3207 | |
44 | E | A | -1.7885 | |
45 | I | A | -0.8023 | |
46 | F | A | 0.0000 | |
47 | L | A | -0.1168 | |
48 | S | A | -0.4585 | |
49 | Q | A | -0.7071 | |
50 | P | A | -0.6002 | |
51 | I | A | 0.0000 | |
52 | L | A | 0.0000 | |
53 | L | A | 0.0000 | |
54 | E | A | -2.5464 | |
55 | L | A | 0.0000 | |
56 | E | A | -3.0450 | |
57 | A | A | -1.9748 | |
58 | P | A | -1.7082 | |
59 | L | A | 0.0000 | |
60 | K | A | -0.5143 | |
61 | I | A | 0.0000 | |
62 | C | A | 0.0000 | |
63 | G | A | 0.0000 | |
64 | D | A | 0.0000 | |
65 | I | A | 0.0000 | |
66 | H | A | 0.0000 | |
67 | G | A | 0.0000 | |
68 | Q | A | 0.0000 | |
69 | Y | A | 0.0000 | |
70 | Y | A | 0.0000 | |
71 | D | A | 0.0000 | |
72 | L | A | 0.0000 | |
73 | L | A | 0.0000 | |
74 | R | A | -1.0142 | |
75 | L | A | 0.0000 | |
76 | F | A | 0.0000 | |
77 | E | A | -1.6599 | |
78 | Y | A | -0.4384 | |
79 | G | A | -0.7428 | |
80 | G | A | -1.1082 | |
81 | F | A | -0.8313 | |
82 | P | A | 0.0000 | |
83 | P | A | -1.4935 | |
84 | E | A | -2.0129 | |
85 | S | A | -1.2889 | |
86 | N | A | -1.4653 | |
87 | Y | A | 0.0000 | |
88 | L | A | 0.0000 | |
89 | F | A | 0.0000 | |
90 | L | A | 0.0000 | |
91 | G | A | 0.0000 | |
92 | D | A | 0.0000 | |
93 | Y | A | 0.0000 | |
94 | V | A | 0.0000 | |
95 | D | A | 0.0000 | |
96 | R | A | -1.6066 | |
97 | G | A | -1.6028 | |
98 | K | A | -2.4955 | |
99 | Q | A | 0.0000 | |
100 | S | A | 0.0000 | |
101 | L | A | 0.0000 | |
102 | E | A | 0.0000 | |
103 | T | A | 0.0000 | |
104 | I | A | 0.0000 | |
105 | C | A | 0.0000 | |
106 | L | A | 0.0000 | |
107 | L | A | 0.0000 | |
108 | L | A | 0.0000 | |
109 | A | A | 0.0000 | |
110 | Y | A | 0.0000 | |
111 | K | A | 0.0000 | |
112 | I | A | 0.0000 | |
113 | K | A | -1.4361 | |
114 | Y | A | -0.9972 | |
115 | P | A | -1.1666 | |
116 | E | A | -2.1936 | |
117 | N | A | -1.9977 | |
118 | F | A | 0.0000 | |
119 | F | A | -0.3016 | |
120 | L | A | 0.0000 | |
121 | L | A | 0.0000 | |
122 | R | A | 0.0000 | |
123 | G | A | 0.0000 | |
124 | N | A | 0.0000 | |
125 | H | A | -0.0229 | |
126 | E | A | 0.0000 | |
127 | C | A | -0.7566 | |
128 | A | A | -0.9056 | |
129 | S | A | -0.2139 | |
130 | I | A | 0.4823 | |
131 | N | A | 0.0000 | |
132 | R | A | -0.5484 | |
133 | I | A | 1.2591 | |
134 | Y | A | 0.5586 | |
135 | G | A | -0.6634 | |
136 | F | A | 0.0000 | |
137 | Y | A | -1.1890 | |
138 | D | A | -1.8516 | |
139 | E | A | -2.0568 | |
140 | C | A | 0.0000 | |
141 | K | A | -2.5399 | |
142 | R | A | -2.8229 | |
143 | R | A | -1.9775 | |
144 | Y | A | -1.6852 | |
145 | N | A | -1.8823 | |
146 | I | A | -1.5382 | |
147 | K | A | -2.3120 | |
148 | L | A | 0.0000 | |
149 | W | A | 0.0000 | |
150 | K | A | -2.5986 | |
151 | T | A | -1.6917 | |
152 | F | A | 0.0000 | |
153 | T | A | -2.0669 | |
154 | D | A | -2.3174 | |
155 | C | A | 0.0000 | |
156 | F | A | 0.0000 | |
157 | N | A | -1.3228 | |
158 | C | A | 0.0000 | |
159 | L | A | 0.0000 | |
160 | P | A | 0.0000 | |
161 | I | A | 0.0000 | |
162 | A | A | 0.0000 | |
163 | A | A | 0.0000 | |
164 | I | A | -1.3153 | |
165 | V | A | 0.0000 | |
166 | D | A | -2.8659 | |
167 | E | A | -3.1929 | |
168 | K | A | -2.3427 | |
169 | I | A | 0.0000 | |
170 | F | A | 0.0000 | |
171 | C | A | 0.0000 | |
172 | C | A | 0.0000 | |
173 | H | A | 0.0000 | |
174 | G | A | 0.0000 | |
175 | G | A | 0.0000 | |
176 | L | A | 0.0000 | |
177 | S | A | 0.0000 | |
178 | P | A | -1.1046 | |
179 | D | A | -2.1823 | |
180 | L | A | 0.0000 | |
181 | Q | A | -2.2153 | |
182 | S | A | -1.8379 | |
183 | M | A | -1.6108 | |
184 | E | A | -2.8773 | |
185 | Q | A | -2.3524 | |
186 | I | A | 0.0000 | |
187 | R | A | -2.4018 | |
188 | R | A | -2.4491 | |
189 | I | A | -0.7072 | |
190 | M | A | 0.4759 | |
191 | R | A | -0.0712 | |
192 | P | A | -0.6580 | |
193 | T | A | -0.9968 | |
194 | D | A | -2.2611 | |
195 | V | A | -1.3595 | |
196 | P | A | -1.7610 | |
197 | D | A | -2.5478 | |
198 | Q | A | -2.0138 | |
199 | G | A | -1.4217 | |
200 | L | A | -0.8448 | |
201 | L | A | 0.0000 | |
202 | C | A | 0.0000 | |
203 | D | A | 0.0000 | |
204 | L | A | 0.0000 | |
205 | L | A | 0.0000 | |
206 | W | A | -0.0676 | |
207 | S | A | 0.0000 | |
208 | D | A | 0.0000 | |
209 | P | A | -0.9107 | |
210 | D | A | -1.8541 | |
211 | K | A | -2.6385 | |
212 | D | A | -2.4014 | |
213 | V | A | -0.9345 | |
214 | L | A | 0.5975 | |
215 | G | A | 0.2455 | |
216 | W | A | 0.3039 | |
217 | G | A | -0.9444 | |
218 | E | A | -2.2660 | |
219 | N | A | 0.0000 | |
220 | D | A | -2.7954 | |
221 | R | A | -2.2090 | |
222 | G | A | -1.6898 | |
223 | V | A | -1.3095 | |
224 | S | A | -1.1786 | |
225 | F | A | -1.0098 | |
226 | T | A | -1.0745 | |
227 | F | A | 0.0000 | |
228 | G | A | 0.0000 | |
229 | A | A | -1.7585 | |
230 | E | A | -1.8530 | |
231 | V | A | -1.0245 | |
232 | V | A | 0.0000 | |
233 | A | A | -2.2216 | |
234 | K | A | -3.1309 | |
235 | F | A | 0.0000 | |
236 | L | A | 0.0000 | |
237 | H | A | -3.1496 | |
238 | K | A | -3.4237 | |
239 | H | A | -2.8747 | |
240 | D | A | -3.3789 | |
241 | L | A | 0.0000 | |
242 | D | A | -2.3446 | |
243 | L | A | 0.0000 | |
244 | I | A | 0.0000 | |
245 | C | A | 0.0000 | |
246 | R | A | 0.0000 | |
247 | A | A | 0.0000 | |
248 | H | A | 0.0000 | |
249 | Q | A | -0.4287 | |
250 | V | A | -0.4353 | |
251 | V | A | 0.0000 | |
252 | E | A | -3.0270 | |
253 | D | A | -3.3500 | |
254 | G | A | 0.0000 | |
255 | Y | A | -1.3160 | |
256 | E | A | -2.0377 | |
257 | F | A | -1.2874 | |
258 | F | A | 0.0000 | |
259 | A | A | 0.0000 | |
260 | K | A | -2.5574 | |
261 | R | A | -2.8334 | |
262 | Q | A | -1.7034 | |
263 | L | A | 0.0000 | |
264 | V | A | 0.0000 | |
265 | T | A | 0.0000 | |
266 | L | A | 0.0000 | |
267 | F | A | 0.0000 | |
268 | S | A | 0.0000 | |
269 | A | A | 0.0000 | |
270 | P | A | 0.0000 | |
271 | N | A | 0.0000 | |
272 | Y | A | -0.6604 | |
273 | C | A | -1.4299 | |
274 | G | A | -2.3947 | |
275 | E | A | -2.1208 | |
276 | F | A | -0.9259 | |
277 | D | A | -2.4987 | |
278 | N | A | 0.0000 | |
279 | A | A | 0.0000 | |
280 | G | A | 0.0000 | |
281 | A | A | 0.0000 | |
282 | M | A | 0.0000 | |
283 | M | A | 0.0000 | |
284 | S | A | -0.5189 | |
285 | V | A | 0.0000 | |
286 | D | A | -1.7603 | |
287 | E | A | -2.7163 | |
288 | T | A | -1.8824 | |
289 | L | A | 0.0000 | |
290 | M | A | -0.5776 | |
291 | C | A | 0.0000 | |
292 | S | A | -0.4349 | |
293 | F | A | 0.0000 | |
294 | Q | A | -0.8892 | |
295 | I | A | 0.0000 | |
296 | L | A | 0.0000 | |
297 | K | A | -1.2665 | |
298 | P | A | -1.2429 | |
299 | A | A | -1.5403 | |
300 | E | A | -2.7796 | |
639 | K | B | -3.1107 | |
640 | K | B | -2.7126 | |
641 | V | B | 0.0000 | |
642 | T | B | -0.8207 | |
643 | F | B | -0.2762 | |
644 | L | B | -0.5685 | |
645 | E | B | -2.2116 | |
646 | E | B | -2.4712 | |
647 | V | B | -1.2610 | |
648 | T | B | -1.3273 | |
649 | E | B | -1.8475 | |
650 | Y | B | -0.0887 | |
651 | Y | B | 0.5249 | |
652 | I | B | 0.0000 | |
653 | S | B | -1.0364 | |
654 | G | B | -2.1606 | |
655 | D | B | 0.0000 | |
656 | E | B | -3.7475 | |
657 | D | B | -3.8546 | |
658 | R | B | -3.6745 |