Project name: 4g3y:L
Status: done
submitted: 2019-03-21 17:29:06, status changed: 2019-03-21 17:36:14
Settings
Chain sequence(s)
|
L: DILLTQSPAILSVSPGERVSFSCRASQFVGSSIHWYQQRTNGSPRLLIKYASESMSGIPSRFSGSGSGTDFTLSINTVESEDIADYYCQQSHSWPFTFGSGTNLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6609
-
Maximal score value
-
2.1102
-
Average score
-
-0.726
-
Total score value
-
-155.3561
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
L |
-1.2428 |
|
2 |
I |
L |
0.0000 |
|
3 |
L |
L |
1.1453 |
|
4 |
L |
L |
0.0000 |
|
5 |
T |
L |
0.0745 |
|
6 |
Q |
L |
0.0000 |
|
7 |
S |
L |
-0.0377 |
|
8 |
P |
L |
0.2375 |
|
9 |
A |
L |
0.5587 |
|
10 |
I |
L |
1.5459 |
|
11 |
L |
L |
0.8517 |
|
12 |
S |
L |
0.1350 |
|
13 |
V |
L |
0.0000 |
|
14 |
S |
L |
-1.7054 |
|
15 |
P |
L |
-2.0889 |
|
16 |
G |
L |
-2.2996 |
|
17 |
E |
L |
-3.3064 |
|
18 |
R |
L |
-3.4210 |
|
19 |
V |
L |
0.0000 |
|
20 |
S |
L |
-0.7290 |
|
21 |
F |
L |
0.0000 |
|
22 |
S |
L |
-0.6297 |
|
23 |
C |
L |
0.0000 |
|
24 |
R |
L |
-1.0002 |
|
25 |
A |
L |
0.0000 |
|
26 |
S |
L |
-0.3786 |
|
27 |
Q |
L |
-0.6083 |
|
28 |
F |
L |
0.8305 |
|
29 |
V |
L |
0.0000 |
|
30 |
G |
L |
-0.0254 |
|
31 |
S |
L |
-0.0962 |
|
32 |
S |
L |
0.1309 |
|
33 |
I |
L |
0.0000 |
|
34 |
H |
L |
0.0000 |
|
35 |
W |
L |
0.0000 |
|
36 |
Y |
L |
-0.5925 |
|
37 |
Q |
L |
0.0000 |
|
38 |
Q |
L |
-2.2185 |
|
39 |
R |
L |
-3.3404 |
|
40 |
T |
L |
-2.3421 |
|
41 |
N |
L |
-2.1233 |
|
42 |
G |
L |
-1.9036 |
|
43 |
S |
L |
-1.5178 |
|
44 |
P |
L |
-1.7521 |
|
45 |
R |
L |
-2.0732 |
|
46 |
L |
L |
-0.5789 |
|
47 |
L |
L |
0.0000 |
|
48 |
I |
L |
0.0000 |
|
49 |
K |
L |
-0.5869 |
|
50 |
Y |
L |
0.1861 |
|
51 |
A |
L |
0.0000 |
|
52 |
S |
L |
-1.0442 |
|
53 |
E |
L |
-1.8459 |
|
54 |
S |
L |
-1.0107 |
|
55 |
M |
L |
-0.4132 |
|
56 |
S |
L |
-0.4705 |
|
57 |
G |
L |
-0.4349 |
|
58 |
I |
L |
-0.2873 |
|
59 |
P |
L |
-0.3349 |
|
60 |
S |
L |
-0.5616 |
|
61 |
R |
L |
-0.9554 |
|
62 |
F |
L |
0.0000 |
|
63 |
S |
L |
-0.8848 |
|
64 |
G |
L |
-0.6813 |
|
65 |
S |
L |
-0.8268 |
|
66 |
G |
L |
-0.9839 |
|
67 |
S |
L |
-0.5970 |
|
68 |
G |
L |
-0.3540 |
|
69 |
T |
L |
-0.9309 |
|
70 |
D |
L |
-2.0934 |
|
71 |
F |
L |
0.0000 |
|
72 |
T |
L |
-0.7432 |
|
73 |
L |
L |
0.0000 |
|
74 |
S |
L |
-0.8886 |
|
75 |
I |
L |
0.0000 |
|
76 |
N |
L |
-2.6582 |
|
77 |
T |
L |
-2.2676 |
|
78 |
V |
L |
0.0000 |
|
79 |
E |
L |
-2.8434 |
|
80 |
S |
L |
-2.5741 |
|
81 |
E |
L |
-3.1142 |
|
82 |
D |
L |
0.0000 |
|
83 |
I |
L |
0.0000 |
|
84 |
A |
L |
0.0000 |
|
85 |
D |
L |
-1.0496 |
|
86 |
Y |
L |
0.0000 |
|
87 |
Y |
L |
0.1522 |
|
88 |
C |
L |
0.0000 |
|
89 |
Q |
L |
0.0000 |
|
90 |
Q |
L |
0.0000 |
|
91 |
S |
L |
0.4571 |
|
92 |
H |
L |
-0.3782 |
|
93 |
S |
L |
0.0488 |
|
94 |
W |
L |
0.7835 |
|
95 |
P |
L |
0.4189 |
|
96 |
F |
L |
1.2948 |
|
97 |
T |
L |
1.2582 |
|
98 |
F |
L |
2.1102 |
|
99 |
G |
L |
0.0000 |
|
100 |
S |
L |
0.2473 |
|
101 |
G |
L |
0.1323 |
|
102 |
T |
L |
0.0000 |
|
103 |
N |
L |
-0.1840 |
|
104 |
L |
L |
0.0000 |
|
105 |
E |
L |
0.0000 |
|
106 |
V |
L |
0.0000 |
|
107 |
K |
L |
-1.2661 |
|
108 |
R |
L |
-1.0816 |
|
109 |
T |
L |
-0.1390 |
|
110 |
V |
L |
0.4757 |
|
111 |
A |
L |
-0.1086 |
|
112 |
A |
L |
-0.1847 |
|
113 |
P |
L |
0.0000 |
|
114 |
S |
L |
-0.1213 |
|
115 |
V |
L |
0.0000 |
|
116 |
F |
L |
1.1183 |
|
117 |
I |
L |
1.1637 |
|
118 |
F |
L |
1.5132 |
|
119 |
P |
L |
-0.0952 |
|
120 |
P |
L |
0.0000 |
|
121 |
S |
L |
-1.7440 |
|
122 |
D |
L |
-3.3329 |
|
123 |
E |
L |
-3.4592 |
|
124 |
Q |
L |
-2.5597 |
|
125 |
L |
L |
-2.5961 |
|
126 |
K |
L |
-3.0497 |
|
127 |
S |
L |
-1.9048 |
|
128 |
G |
L |
-1.5562 |
|
129 |
T |
L |
-1.4432 |
|
130 |
A |
L |
0.0000 |
|
131 |
S |
L |
0.0461 |
|
132 |
V |
L |
0.0000 |
|
133 |
V |
L |
0.7019 |
|
134 |
C |
L |
0.0000 |
|
135 |
L |
L |
0.4472 |
|
136 |
L |
L |
0.0000 |
|
137 |
N |
L |
-0.3410 |
|
138 |
N |
L |
-1.1678 |
|
139 |
F |
L |
0.0000 |
|
140 |
Y |
L |
0.0000 |
|
141 |
P |
L |
-1.3162 |
|
142 |
R |
L |
-2.0426 |
|
143 |
E |
L |
-2.7697 |
|
144 |
A |
L |
-2.0539 |
|
145 |
K |
L |
-2.4092 |
|
146 |
V |
L |
-1.0441 |
|
147 |
Q |
L |
-0.6106 |
|
148 |
W |
L |
0.0000 |
|
149 |
K |
L |
-0.5180 |
|
150 |
V |
L |
0.0000 |
|
151 |
D |
L |
-1.8359 |
|
152 |
N |
L |
-1.4961 |
|
153 |
A |
L |
-0.2929 |
|
154 |
L |
L |
0.6805 |
|
155 |
Q |
L |
-0.1850 |
|
156 |
S |
L |
-0.4071 |
|
157 |
G |
L |
-0.9746 |
|
158 |
N |
L |
-0.8911 |
|
159 |
S |
L |
-1.3673 |
|
160 |
Q |
L |
-2.2712 |
|
161 |
E |
L |
-2.2048 |
|
162 |
S |
L |
-0.7210 |
|
163 |
V |
L |
0.5741 |
|
164 |
T |
L |
-0.5385 |
|
165 |
E |
L |
-2.1808 |
|
166 |
Q |
L |
0.0000 |
|
167 |
D |
L |
-2.4995 |
|
168 |
S |
L |
-2.9005 |
|
169 |
K |
L |
-2.9094 |
|
170 |
D |
L |
-2.1541 |
|
171 |
S |
L |
0.0000 |
|
172 |
T |
L |
0.0000 |
|
173 |
Y |
L |
0.0000 |
|
174 |
S |
L |
-0.4737 |
|
175 |
L |
L |
0.0000 |
|
176 |
S |
L |
-0.2151 |
|
177 |
S |
L |
0.0000 |
|
178 |
T |
L |
-0.6265 |
|
179 |
L |
L |
0.0000 |
|
180 |
T |
L |
-0.3408 |
|
181 |
L |
L |
-0.7488 |
|
182 |
S |
L |
-1.1680 |
|
183 |
K |
L |
-2.1282 |
|
184 |
A |
L |
-2.0648 |
|
185 |
D |
L |
-3.0208 |
|
186 |
Y |
L |
0.0000 |
|
187 |
E |
L |
-3.3612 |
|
188 |
K |
L |
-3.6609 |
|
189 |
H |
L |
-3.1297 |
|
190 |
K |
L |
-3.0383 |
|
191 |
V |
L |
-1.4807 |
|
192 |
Y |
L |
0.0000 |
|
193 |
A |
L |
-0.6970 |
|
194 |
C |
L |
0.0000 |
|
195 |
E |
L |
-0.7885 |
|
196 |
V |
L |
0.0000 |
|
197 |
T |
L |
-1.0951 |
|
198 |
H |
L |
0.0000 |
|
199 |
Q |
L |
-1.6909 |
|
200 |
G |
L |
-0.4839 |
|
201 |
L |
L |
-0.1854 |
|
202 |
S |
L |
-0.4255 |
|
203 |
S |
L |
-0.3651 |
|
204 |
P |
L |
-0.5641 |
|
205 |
V |
L |
0.1404 |
|
206 |
T |
L |
-0.4113 |
|
207 |
K |
L |
-0.5005 |
|
208 |
S |
L |
-0.4241 |
|
209 |
F |
L |
-0.6252 |
|
210 |
N |
L |
-1.5936 |
|
211 |
R |
L |
-2.2939 |
|
212 |
G |
L |
-2.0750 |
|
213 |
E |
L |
-2.0626 |
|
214 |
C |
L |
-0.3219 |
|