Project name: 5d2f3c2b1ae1e20

Chain sequence(s)	H: EVQLVQSGGGLVKPGGSLRLSCAASGYTFTNYWIGWVRQTPGKGLEWVGDIYPGSSFTNSNEKFKGRFTISADKSKNTAYLQMNSLRAEDTAVYYCARLGRGYWYFDVWGQGTLVTVSS; L: DIVLTQSPATLSASLGERATLSCSASSSVSYIHWYQQKPGQAPKLLIYTTSNLASGVPSRFSGSGSGTDFTLTISSLEAEDFATYYCHQWSRYPTFGGGTKLEIK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0039
• Maximal score value: 1.8329
• Average score: -0.5771
• Total score value: -129.2709

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	L	-1.6446
2	I	L	0.0000
3	V	L	1.1625
4	L	L	0.0000
5	T	L	-0.1028
6	Q	L	-0.2587
7	S	L	-0.4214
8	P	L	-0.4589
9	A	L	-0.4310
10	T	L	-0.8329
11	L	L	-0.5208
12	S	L	-0.9876
13	A	L	-1.1658
14	S	L	-1.1506
15	L	L	-0.1694
16	G	L	-1.4197
17	E	L	-2.6859
18	R	L	-2.7718
19	A	L	0.0000
20	T	L	-0.5299
21	L	L	0.0000
22	S	L	-0.6565
23	C	L	0.0000
24	S	L	-0.8011
25	A	L	0.0000
26	S	L	-0.1547
27	S	L	-0.3782
28	S	L	-0.5102
29	V	L	0.0000
31	S	L	-0.1351
32	Y	L	0.3159
33	I	L	0.0000
34	H	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	0.0000
39	K	L	-1.5797
40	P	L	-1.2384
41	G	L	-1.4942
42	Q	L	-2.1269
43	A	L	-1.4262
44	P	L	0.0000
45	K	L	-1.5034
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	0.3626
50	T	L	0.0000
51	T	L	0.0000
52	S	L	-0.4998
53	N	L	-0.4950
54	L	L	-0.0437
55	A	L	-0.3580
56	S	L	-0.5219
57	G	L	-0.5546
58	V	L	0.0000
59	P	L	-0.4092
60	S	L	-0.4721
61	R	L	-0.8048
62	F	L	0.0000
63	S	L	-0.4805
64	G	L	-0.4464
65	S	L	-0.8464
66	G	L	-1.0410
67	S	L	-0.9897
68	G	L	-0.9192
69	T	L	-1.2579
70	D	L	-2.1248
71	F	L	0.0000
72	T	L	-0.7382
73	L	L	0.0000
74	T	L	-0.6378
75	I	L	0.0000
76	S	L	-1.6115
77	S	L	-1.4942
78	L	L	0.0000
79	E	L	-1.3482
80	A	L	-1.1399
81	E	L	-1.8919
82	D	L	0.0000
83	F	L	-0.5965
84	A	L	0.0000
85	T	L	-0.8939
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	H	L	0.0000
90	Q	L	0.0000
91	W	L	0.0000
92	S	L	-1.0334
93	R	L	-2.1190
94	Y	L	-1.2300
96	P	L	0.0000
97	T	L	-0.2206
98	F	L	0.0899
99	G	L	0.0000
100	G	L	-0.7235
101	G	L	-0.8334
102	T	L	0.0000
103	K	L	-1.5477
104	L	L	0.0000
105	E	L	-1.8383
106	I	L	-0.9782
107	K	L	-1.5060
1	E	H	-1.4869
2	V	H	0.0842
3	Q	H	-0.6783
4	L	H	0.0000
5	V	H	0.8113
6	Q	H	0.0000
7	S	H	-0.3433
8	G	H	-0.3919
9	G	H	-0.0134
10	G	H	0.5068
11	L	H	1.2184
12	V	H	-0.2844
13	K	H	-1.9242
14	P	H	-2.1263
15	G	H	-1.5926
16	G	H	-1.3860
17	S	H	-1.3628
18	L	H	-0.8788
19	R	H	-1.6126
20	L	H	0.0000
21	S	H	-0.4086
22	C	H	0.0000
23	A	H	-0.4671
24	A	H	0.0000
25	S	H	-0.6123
26	G	H	-0.5814
27	Y	H	-0.3039
28	T	H	-0.4840
29	F	H	0.0000
30	T	H	-0.8096
31	N	H	-1.2765
32	Y	H	-0.5218
33	W	H	-0.0500
34	I	H	0.0000
35	G	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.7534
39	Q	H	-0.9269
40	T	H	-1.1607
41	P	H	-0.9782
42	G	H	-1.5297
43	K	H	-2.3788
44	G	H	-1.6132
45	L	H	0.0000
46	E	H	-1.7473
47	W	H	0.0000
48	V	H	0.0000
49	G	H	0.0000
50	D	H	0.0000
51	I	H	0.0000
52	Y	H	0.9843
52A	P	H	0.0000
53	G	H	-0.2114
54	S	H	0.4829
55	S	H	0.6592
56	F	H	1.8329
57	T	H	0.6498
58	N	H	-0.8988
59	S	H	-1.6043
60	N	H	-2.2238
61	E	H	-2.8125
62	K	H	-3.0039
63	F	H	0.0000
64	K	H	-2.9477
65	G	H	-1.8576
66	R	H	-1.2253
67	F	H	-1.1718
68	T	H	-0.7956
69	I	H	0.0643
70	S	H	0.0541
71	A	H	-0.7491
72	D	H	-2.0143
73	K	H	-2.1966
74	S	H	-1.8861
75	K	H	-2.6381
76	N	H	-2.0642
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	0.0000
80	L	H	0.0000
81	Q	H	-1.0397
82	M	H	0.0000
82A	N	H	-1.3746
82B	S	H	-1.3959
82C	L	H	0.0000
83	R	H	-2.6021
84	A	H	-1.8880
85	E	H	-2.2957
86	D	H	0.0000
87	T	H	-0.5087
88	A	H	0.0000
89	V	H	0.3439
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0000
95	L	H	0.0000
96	G	H	-0.6925
97	R	H	-1.4428
98	G	H	-0.5615
99	Y	H	0.6455
100	W	H	0.3714
100A	Y	H	0.3177
100B	F	H	0.0000
101	D	H	-0.8217
102	V	H	-0.3113
103	W	H	0.0000
104	G	H	0.0000
105	Q	H	-1.1492
106	G	H	-0.5046
107	T	H	0.0000
108	L	H	0.9635
109	V	H	0.0000
110	T	H	0.1032
111	V	H	0.0000
112	S	H	-0.8537
113	S	H	-0.6636