Project name: 6bgt:A
Status: done
submitted: 2019-03-21 14:53:58, status changed: 2019-03-21 15:03:10
Settings
Chain sequence(s)
|
A: DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSADFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7186
-
Maximal score value
-
1.7495
-
Average score
-
-0.8408
-
Total score value
-
-177.4033
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
A |
-2.2959 |
|
2 |
I |
A |
0.0000 |
|
3 |
Q |
A |
-2.0383 |
|
4 |
M |
A |
0.0000 |
|
5 |
T |
A |
-1.1950 |
|
6 |
Q |
A |
0.0000 |
|
7 |
S |
A |
-0.7975 |
|
8 |
P |
A |
-0.6604 |
|
9 |
S |
A |
-0.9216 |
|
10 |
S |
A |
-0.8071 |
|
11 |
L |
A |
-0.5794 |
|
12 |
S |
A |
-0.9017 |
|
13 |
A |
A |
-1.1919 |
|
14 |
S |
A |
-1.1999 |
|
15 |
V |
A |
-0.3950 |
|
16 |
G |
A |
-1.2387 |
|
17 |
D |
A |
-2.3929 |
|
18 |
R |
A |
-2.6465 |
|
19 |
V |
A |
0.0000 |
|
20 |
T |
A |
-0.7074 |
|
21 |
I |
A |
0.0000 |
|
22 |
T |
A |
-0.9223 |
|
23 |
C |
A |
0.0000 |
|
24 |
R |
A |
-2.9315 |
|
25 |
A |
A |
0.0000 |
|
26 |
S |
A |
-2.1423 |
|
27 |
Q |
A |
-2.8705 |
|
28 |
D |
A |
-2.9355 |
|
29 |
V |
A |
0.0000 |
|
30 |
N |
A |
-2.1249 |
|
31 |
T |
A |
-1.3677 |
|
32 |
A |
A |
-0.5710 |
|
33 |
V |
A |
0.0000 |
|
34 |
A |
A |
0.5541 |
|
35 |
W |
A |
0.0000 |
|
36 |
Y |
A |
0.1127 |
|
37 |
Q |
A |
0.0000 |
|
38 |
Q |
A |
-1.4404 |
|
39 |
K |
A |
-1.9023 |
|
40 |
P |
A |
-1.5653 |
|
41 |
G |
A |
-1.5341 |
|
42 |
K |
A |
-2.3773 |
|
43 |
A |
A |
-1.4040 |
|
44 |
P |
A |
-1.3315 |
|
45 |
K |
A |
-1.4206 |
|
46 |
L |
A |
0.0438 |
|
47 |
L |
A |
0.0000 |
|
48 |
I |
A |
0.0000 |
|
49 |
Y |
A |
1.2998 |
|
50 |
S |
A |
0.0058 |
|
51 |
A |
A |
0.0000 |
|
52 |
D |
A |
-0.8014 |
|
53 |
F |
A |
1.5545 |
|
54 |
L |
A |
1.4224 |
|
55 |
Y |
A |
1.2181 |
|
56 |
S |
A |
0.3173 |
|
57 |
G |
A |
-0.3056 |
|
58 |
V |
A |
0.0000 |
|
59 |
P |
A |
-0.3348 |
|
60 |
S |
A |
-0.3907 |
|
61 |
R |
A |
-0.8201 |
|
62 |
F |
A |
0.0000 |
|
63 |
S |
A |
-0.2595 |
|
64 |
G |
A |
-0.7193 |
|
65 |
S |
A |
-1.6218 |
|
66 |
R |
A |
-3.0079 |
|
67 |
S |
A |
-1.9010 |
|
68 |
G |
A |
-2.1252 |
|
69 |
T |
A |
-2.4595 |
|
70 |
D |
A |
-2.2655 |
|
71 |
F |
A |
0.0000 |
|
72 |
T |
A |
-1.2794 |
|
73 |
L |
A |
0.0000 |
|
74 |
T |
A |
-0.6442 |
|
75 |
I |
A |
0.0000 |
|
76 |
S |
A |
-1.5976 |
|
77 |
S |
A |
-1.4602 |
|
78 |
L |
A |
0.0000 |
|
79 |
Q |
A |
-1.0452 |
|
80 |
P |
A |
-1.5405 |
|
81 |
E |
A |
-1.3472 |
|
82 |
D |
A |
0.0000 |
|
83 |
F |
A |
0.0000 |
|
84 |
A |
A |
0.0000 |
|
85 |
T |
A |
-0.9229 |
|
86 |
Y |
A |
0.0000 |
|
87 |
Y |
A |
0.0141 |
|
88 |
C |
A |
0.0000 |
|
89 |
Q |
A |
0.2407 |
|
90 |
Q |
A |
0.0000 |
|
91 |
H |
A |
-0.5527 |
|
92 |
Y |
A |
-0.1186 |
|
93 |
T |
A |
-0.2909 |
|
94 |
T |
A |
-0.5587 |
|
95 |
P |
A |
-0.5622 |
|
96 |
P |
A |
-0.5019 |
|
97 |
T |
A |
-0.2268 |
|
98 |
F |
A |
0.8332 |
|
99 |
G |
A |
-0.3818 |
|
100 |
Q |
A |
-1.1703 |
|
101 |
G |
A |
0.0000 |
|
102 |
T |
A |
0.0000 |
|
103 |
K |
A |
-1.6157 |
|
104 |
V |
A |
0.0000 |
|
105 |
E |
A |
-1.2279 |
|
106 |
I |
A |
0.0000 |
|
107 |
K |
A |
-1.6397 |
|
108 |
R |
A |
-0.8944 |
|
109 |
T |
A |
-0.0223 |
|
110 |
V |
A |
0.5524 |
|
111 |
A |
A |
0.1501 |
|
112 |
A |
A |
-0.1346 |
|
113 |
P |
A |
0.0000 |
|
114 |
S |
A |
-0.1860 |
|
115 |
V |
A |
0.0000 |
|
116 |
F |
A |
1.1633 |
|
117 |
I |
A |
1.3519 |
|
118 |
F |
A |
1.7495 |
|
119 |
P |
A |
0.0729 |
|
120 |
P |
A |
-0.6148 |
|
121 |
S |
A |
-1.7349 |
|
122 |
D |
A |
-3.2364 |
|
123 |
E |
A |
-3.3581 |
|
124 |
Q |
A |
-2.4302 |
|
125 |
L |
A |
-2.5401 |
|
126 |
K |
A |
-2.9789 |
|
127 |
S |
A |
-1.9050 |
|
128 |
G |
A |
-1.3468 |
|
129 |
T |
A |
-1.1323 |
|
130 |
A |
A |
0.0000 |
|
131 |
S |
A |
0.0283 |
|
132 |
V |
A |
0.0000 |
|
133 |
V |
A |
0.7660 |
|
134 |
C |
A |
0.0000 |
|
135 |
L |
A |
0.5420 |
|
136 |
L |
A |
0.0000 |
|
137 |
N |
A |
-0.7143 |
|
138 |
N |
A |
-1.2613 |
|
139 |
F |
A |
0.0000 |
|
140 |
Y |
A |
0.0000 |
|
141 |
P |
A |
-1.6119 |
|
142 |
R |
A |
-2.6282 |
|
143 |
E |
A |
-3.0660 |
|
144 |
A |
A |
-2.2431 |
|
145 |
K |
A |
-2.2591 |
|
146 |
V |
A |
-1.2580 |
|
147 |
Q |
A |
-0.6421 |
|
148 |
W |
A |
0.0000 |
|
149 |
K |
A |
-0.6321 |
|
150 |
V |
A |
0.0000 |
|
151 |
D |
A |
-1.8129 |
|
152 |
N |
A |
-1.4076 |
|
153 |
A |
A |
-0.3154 |
|
154 |
L |
A |
0.7205 |
|
155 |
Q |
A |
-0.3255 |
|
156 |
S |
A |
-0.6809 |
|
157 |
G |
A |
-1.3812 |
|
158 |
N |
A |
-1.6362 |
|
159 |
S |
A |
-1.7940 |
|
160 |
Q |
A |
-2.4537 |
|
161 |
E |
A |
-2.3425 |
|
162 |
S |
A |
-1.3634 |
|
163 |
V |
A |
-0.7590 |
|
164 |
T |
A |
-1.1223 |
|
165 |
E |
A |
-2.3182 |
|
166 |
Q |
A |
0.0000 |
|
167 |
D |
A |
-2.5305 |
|
168 |
S |
A |
-2.2678 |
|
169 |
K |
A |
-2.6910 |
|
170 |
D |
A |
-2.1883 |
|
171 |
S |
A |
0.0000 |
|
172 |
T |
A |
0.0000 |
|
173 |
Y |
A |
0.0000 |
|
174 |
S |
A |
-1.0046 |
|
175 |
L |
A |
0.0000 |
|
176 |
S |
A |
-0.5480 |
|
177 |
S |
A |
0.0000 |
|
178 |
T |
A |
-0.6150 |
|
179 |
L |
A |
0.0000 |
|
180 |
T |
A |
-0.7021 |
|
181 |
L |
A |
-0.8571 |
|
182 |
S |
A |
-1.1770 |
|
183 |
K |
A |
-2.3213 |
|
184 |
A |
A |
-1.9796 |
|
185 |
D |
A |
-2.4045 |
|
186 |
Y |
A |
0.0000 |
|
187 |
E |
A |
-3.7186 |
|
188 |
K |
A |
-3.5243 |
|
189 |
H |
A |
-3.1687 |
|
190 |
K |
A |
-3.2316 |
|
191 |
V |
A |
-1.8109 |
|
192 |
Y |
A |
0.0000 |
|
193 |
A |
A |
0.0000 |
|
194 |
C |
A |
0.0000 |
|
195 |
E |
A |
-0.6842 |
|
196 |
V |
A |
0.0000 |
|
197 |
T |
A |
-1.1858 |
|
198 |
H |
A |
0.0000 |
|
199 |
Q |
A |
-1.6509 |
|
200 |
G |
A |
-0.3175 |
|
201 |
L |
A |
-0.0880 |
|
202 |
S |
A |
-0.4357 |
|
203 |
S |
A |
-0.4146 |
|
204 |
P |
A |
-0.5742 |
|
205 |
V |
A |
-0.1236 |
|
206 |
T |
A |
-0.4250 |
|
207 |
K |
A |
-0.4201 |
|
208 |
S |
A |
-0.4371 |
|
209 |
F |
A |
-0.7788 |
|
210 |
N |
A |
-2.2506 |
|
211 |
R |
A |
-2.5389 |
|