Project name: 6bhz:L
Status: done
submitted: 2019-03-21 14:54:44, status changed: 2019-03-21 15:03:15
Settings
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSSRSGTDFTTLTISSLQPEDFATYYCCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKAAYEKHKVYACCEVTHQGLSSPVTKSFNRGE
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4382
-
Maximal score value
-
2.3993
-
Average score
-
-0.8059
-
Total score value
-
-171.6489
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
L |
-2.3282 |
|
2 |
I |
L |
0.0000 |
|
3 |
Q |
L |
-2.1303 |
|
4 |
M |
L |
0.0000 |
|
5 |
T |
L |
-1.2857 |
|
6 |
Q |
L |
0.0000 |
|
7 |
S |
L |
-0.9423 |
|
8 |
P |
L |
-0.7369 |
|
9 |
S |
L |
-1.0510 |
|
10 |
S |
L |
-1.0739 |
|
11 |
L |
L |
-0.6674 |
|
12 |
S |
L |
-0.7002 |
|
13 |
A |
L |
-0.7784 |
|
14 |
S |
L |
-0.5284 |
|
15 |
V |
L |
0.2876 |
|
16 |
G |
L |
-0.4375 |
|
17 |
D |
L |
-1.5749 |
|
18 |
R |
L |
-2.2143 |
|
19 |
V |
L |
0.0000 |
|
20 |
T |
L |
-0.6305 |
|
21 |
I |
L |
0.0000 |
|
22 |
T |
L |
-0.8843 |
|
23 |
C |
L |
0.0000 |
|
24 |
R |
L |
-3.0120 |
|
25 |
A |
L |
0.0000 |
|
26 |
S |
L |
-2.2847 |
|
27 |
Q |
L |
-2.8675 |
|
28 |
D |
L |
-2.9179 |
|
29 |
V |
L |
0.0000 |
|
30 |
N |
L |
-2.1500 |
|
31 |
T |
L |
-1.2230 |
|
32 |
A |
L |
-0.4432 |
|
33 |
V |
L |
0.0000 |
|
34 |
A |
L |
0.6507 |
|
35 |
W |
L |
0.0000 |
|
36 |
Y |
L |
-0.0204 |
|
37 |
Q |
L |
0.0000 |
|
38 |
Q |
L |
-1.5648 |
|
39 |
K |
L |
-2.0366 |
|
40 |
P |
L |
-1.4565 |
|
41 |
G |
L |
-1.5085 |
|
42 |
K |
L |
-2.4003 |
|
43 |
A |
L |
-1.4722 |
|
44 |
P |
L |
-1.4581 |
|
45 |
K |
L |
-1.6246 |
|
46 |
L |
L |
-0.0284 |
|
47 |
L |
L |
0.0000 |
|
48 |
I |
L |
0.0000 |
|
49 |
Y |
L |
1.6422 |
|
50 |
S |
L |
0.3439 |
|
51 |
A |
L |
0.0000 |
|
52 |
S |
L |
0.6020 |
|
53 |
F |
L |
2.3993 |
|
54 |
L |
L |
1.9094 |
|
55 |
Y |
L |
1.4463 |
|
56 |
S |
L |
0.4060 |
|
57 |
G |
L |
-0.2030 |
|
58 |
V |
L |
-0.0163 |
|
59 |
P |
L |
-0.1938 |
|
60 |
S |
L |
-0.2829 |
|
61 |
R |
L |
-0.7267 |
|
62 |
F |
L |
0.0000 |
|
63 |
S |
L |
0.1896 |
|
64 |
G |
L |
-0.0967 |
|
65 |
S |
L |
-1.1436 |
|
66 |
R |
L |
-2.7721 |
|
67 |
S |
L |
-1.9341 |
|
68 |
G |
L |
-2.1970 |
|
69 |
T |
L |
-2.5915 |
|
70 |
D |
L |
-2.5018 |
|
71 |
F |
L |
0.0000 |
|
72 |
T |
L |
-1.0761 |
|
73 |
L |
L |
0.0000 |
|
74 |
T |
L |
-0.6373 |
|
75 |
I |
L |
0.0000 |
|
76 |
S |
L |
-1.3555 |
|
77 |
S |
L |
-0.9746 |
|
78 |
L |
L |
0.0000 |
|
79 |
Q |
L |
-0.6617 |
|
80 |
P |
L |
-1.4279 |
|
81 |
E |
L |
-2.1815 |
|
82 |
D |
L |
0.0000 |
|
83 |
F |
L |
-1.3324 |
|
84 |
A |
L |
0.0000 |
|
85 |
T |
L |
-1.0679 |
|
86 |
Y |
L |
0.0000 |
|
87 |
Y |
L |
-0.1158 |
|
88 |
C |
L |
0.0000 |
|
89 |
Q |
L |
0.2046 |
|
90 |
Q |
L |
0.0000 |
|
91 |
H |
L |
-0.5152 |
|
92 |
Y |
L |
0.0292 |
|
93 |
T |
L |
-0.1877 |
|
94 |
T |
L |
-0.5641 |
|
95 |
P |
L |
-0.6036 |
|
96 |
P |
L |
-0.5429 |
|
97 |
T |
L |
-0.3015 |
|
98 |
F |
L |
0.6789 |
|
99 |
G |
L |
0.0000 |
|
100 |
Q |
L |
-1.2085 |
|
101 |
G |
L |
0.0000 |
|
102 |
T |
L |
0.0000 |
|
103 |
K |
L |
-2.0382 |
|
104 |
V |
L |
0.0000 |
|
105 |
E |
L |
-1.1815 |
|
106 |
I |
L |
0.0000 |
|
107 |
K |
L |
-0.9537 |
|
108 |
R |
L |
-0.6481 |
|
109 |
T |
L |
-0.0931 |
|
110 |
V |
L |
0.1718 |
|
111 |
A |
L |
-0.2488 |
|
112 |
A |
L |
-0.2882 |
|
113 |
P |
L |
0.0000 |
|
114 |
S |
L |
-0.1463 |
|
115 |
V |
L |
0.0000 |
|
116 |
F |
L |
1.3251 |
|
117 |
I |
L |
1.2705 |
|
118 |
F |
L |
1.4723 |
|
119 |
P |
L |
0.0317 |
|
120 |
P |
L |
-0.7167 |
|
121 |
S |
L |
-1.8040 |
|
122 |
D |
L |
-3.2420 |
|
123 |
E |
L |
-3.4382 |
|
124 |
Q |
L |
-2.4867 |
|
125 |
L |
L |
-2.5723 |
|
126 |
K |
L |
-3.0413 |
|
127 |
S |
L |
-1.9585 |
|
128 |
G |
L |
-1.3813 |
|
129 |
T |
L |
-1.0622 |
|
130 |
A |
L |
0.0000 |
|
131 |
S |
L |
-0.0777 |
|
132 |
V |
L |
0.0000 |
|
133 |
V |
L |
0.6781 |
|
134 |
C |
L |
0.0000 |
|
135 |
L |
L |
0.4765 |
|
136 |
L |
L |
0.0000 |
|
137 |
N |
L |
-0.6104 |
|
138 |
N |
L |
-1.4629 |
|
139 |
F |
L |
0.0000 |
|
140 |
Y |
L |
0.0000 |
|
141 |
P |
L |
-1.8223 |
|
142 |
R |
L |
-3.1367 |
|
143 |
E |
L |
-3.2528 |
|
144 |
A |
L |
-2.3320 |
|
145 |
K |
L |
-2.3979 |
|
146 |
V |
L |
-1.1190 |
|
147 |
Q |
L |
-0.7224 |
|
148 |
W |
L |
0.0000 |
|
149 |
K |
L |
-0.7395 |
|
150 |
V |
L |
0.0000 |
|
151 |
D |
L |
-2.0245 |
|
152 |
N |
L |
-1.6114 |
|
153 |
A |
L |
-0.3151 |
|
154 |
L |
L |
0.6654 |
|
155 |
Q |
L |
-0.3022 |
|
156 |
S |
L |
-0.5907 |
|
157 |
G |
L |
-1.2115 |
|
158 |
N |
L |
-1.3788 |
|
159 |
S |
L |
-1.6358 |
|
160 |
Q |
L |
-2.3785 |
|
161 |
E |
L |
-2.3170 |
|
162 |
S |
L |
-1.2610 |
|
163 |
V |
L |
-0.6503 |
|
164 |
T |
L |
-1.2288 |
|
165 |
E |
L |
-2.2808 |
|
166 |
Q |
L |
0.0000 |
|
167 |
D |
L |
-2.6231 |
|
168 |
S |
L |
-2.3672 |
|
169 |
K |
L |
-2.6469 |
|
170 |
D |
L |
-1.9539 |
|
171 |
S |
L |
0.0000 |
|
172 |
T |
L |
0.0000 |
|
173 |
Y |
L |
0.0000 |
|
174 |
S |
L |
-1.0516 |
|
175 |
L |
L |
0.0000 |
|
176 |
S |
L |
-0.4565 |
|
177 |
S |
L |
0.0000 |
|
178 |
T |
L |
-0.7107 |
|
179 |
L |
L |
0.0000 |
|
180 |
T |
L |
-0.5456 |
|
181 |
L |
L |
-0.4703 |
|
182 |
S |
L |
-0.7029 |
|
183 |
K |
L |
-1.7580 |
|
184 |
A |
L |
-1.2618 |
|
185 |
A |
L |
-1.3312 |
|
186 |
Y |
L |
0.0000 |
|
187 |
E |
L |
-3.0123 |
|
188 |
K |
L |
-3.1803 |
|
189 |
H |
L |
-2.7941 |
|
190 |
K |
L |
-3.3192 |
|
191 |
V |
L |
-1.5667 |
|
192 |
Y |
L |
0.0000 |
|
193 |
A |
L |
0.0000 |
|
194 |
C |
L |
0.0000 |
|
195 |
E |
L |
-0.8607 |
|
196 |
V |
L |
0.0000 |
|
197 |
T |
L |
-1.1800 |
|
198 |
H |
L |
0.0000 |
|
199 |
Q |
L |
-1.7457 |
|
200 |
G |
L |
-0.4705 |
|
201 |
L |
L |
-0.2193 |
|
202 |
S |
L |
-0.4328 |
|
203 |
S |
L |
-0.4232 |
|
204 |
P |
L |
-0.5347 |
|
205 |
V |
L |
-0.0482 |
|
206 |
T |
L |
-0.3884 |
|
207 |
K |
L |
-0.2852 |
|
208 |
S |
L |
-0.2795 |
|
209 |
F |
L |
-0.7465 |
|
210 |
N |
L |
-1.9599 |
|
211 |
R |
L |
-2.5383 |
|
212 |
G |
L |
-2.1627 |
|
213 |
E |
L |
-2.4944 |
|