Project name: 3hmw:H

Chain sequence(s)	H: EVQLVQSGAEVKKPGESLKISCKGSGYSFTTYWLGWVRQMPGKGLDWIGIMSPVDSDIRYSPSFQGQVTMSVDKSITTAYLQWNSLKASDTAMYYCARRRPGQGYFDFWGQGTLVTVSSSSTKGPSVFPLAPSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8759
• Maximal score value: 2.3765
• Average score: -0.5749
• Total score value: -125.3301

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.0355
2	V	H	-0.9481
3	Q	H	-1.2642
4	L	H	0.0000
5	V	H	0.1879
6	Q	H	0.0000
7	S	H	-0.5541
8	G	H	-0.7248
9	A	H	-0.6131
10	E	H	-0.7131
11	V	H	-0.4747
12	K	H	-1.4896
13	K	H	-2.5352
14	P	H	-2.2297
15	G	H	-2.0573
16	E	H	-2.0933
17	S	H	-2.0441
18	L	H	0.0000
19	K	H	-2.1211
20	I	H	0.0000
21	S	H	-0.5472
22	C	H	0.0000
23	K	H	-0.4135
24	G	H	0.0000
25	S	H	-0.6861
26	G	H	-1.0692
27	Y	H	-0.4390
28	S	H	-0.1280
29	F	H	0.0000
30	T	H	-0.1265
31	T	H	-0.0374
32	Y	H	-0.1264
33	W	H	-0.1575
34	L	H	0.0000
35	G	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.1060
39	Q	H	-0.4369
40	M	H	-0.7179
41	P	H	-1.0399
42	G	H	-1.3774
43	K	H	-2.0303
44	G	H	-0.9124
45	L	H	0.7033
46	D	H	0.1142
47	W	H	0.8160
48	I	H	0.0000
49	G	H	0.0000
50	I	H	0.0000
51	M	H	0.0000
52	S	H	0.0000
53	P	H	0.0000
54	V	H	-0.3925
55	D	H	-1.9050
56	S	H	-1.5171
57	D	H	-2.2216
58	I	H	-1.1346
59	R	H	-1.8636
60	Y	H	-0.9217
61	S	H	-0.7467
62	P	H	-0.9899
63	S	H	-0.8350
64	F	H	0.0000
65	Q	H	-2.0283
66	G	H	-1.5071
67	Q	H	-1.8055
68	V	H	0.0000
69	T	H	-0.9242
70	M	H	0.0000
71	S	H	-0.3235
72	V	H	-0.2806
73	D	H	-0.6025
74	K	H	-0.9628
75	S	H	-0.1214
76	I	H	0.8919
77	T	H	-0.1319
78	T	H	0.0000
79	A	H	0.0000
80	Y	H	-0.5040
81	L	H	0.0000
82	Q	H	-1.5973
83	W	H	0.0000
84	N	H	-2.2766
85	S	H	-2.0696
86	L	H	0.0000
87	K	H	-2.5824
88	A	H	-1.4231
89	S	H	-0.8582
90	D	H	-0.8748
91	T	H	-0.4625
92	A	H	0.0000
93	M	H	0.2026
94	Y	H	0.0000
95	Y	H	0.3209
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	R	H	-1.1362
100	R	H	-2.1084
101	P	H	-1.6332
102	G	H	-1.5704
103	Q	H	-2.0483
104	G	H	-1.1894
105	Y	H	-0.1085
106	F	H	0.0000
107	D	H	-0.3060
108	F	H	0.7873
109	W	H	0.7348
110	G	H	0.0000
111	Q	H	-0.7927
112	G	H	-0.3107
113	T	H	0.0000
114	L	H	-0.1455
115	V	H	0.0000
116	T	H	-0.6238
117	V	H	0.0000
118	S	H	-1.2258
119	S	H	-1.0060
120	S	H	-0.7741
121	S	H	-0.7496
122	T	H	-0.6536
123	K	H	-1.0988
124	G	H	-1.3469
125	P	H	0.0000
126	S	H	-0.1074
127	V	H	0.0000
128	F	H	0.7972
129	P	H	0.0334
130	L	H	0.1801
131	A	H	-0.8410
132	P	H	0.0000
133	S	H	-0.4585
137	T	H	-0.2724
138	S	H	-0.6259
139	G	H	-0.9373
140	G	H	-0.9086
141	T	H	-0.5711
142	A	H	0.0000
143	A	H	0.0426
144	L	H	0.0000
145	G	H	0.0000
146	C	H	0.0000
147	L	H	0.7134
148	V	H	0.0000
149	K	H	-0.1696
150	D	H	-0.3719
151	Y	H	0.0000
152	F	H	-0.3682
153	P	H	0.0000
154	E	H	-0.9911
155	P	H	-1.0132
156	V	H	-0.5921
157	T	H	-0.6111
158	V	H	-0.1837
159	S	H	-0.3381
160	W	H	0.0000
161	N	H	-0.7485
162	S	H	-0.6238
163	G	H	-0.4354
164	A	H	-0.1780
165	L	H	0.0188
166	T	H	-0.2902
167	S	H	-0.4014
168	G	H	-0.5145
169	V	H	-0.1017
170	H	H	-0.5976
171	T	H	0.0878
172	F	H	0.7075
173	P	H	0.6086
174	A	H	1.0800
175	V	H	2.3765
176	L	H	1.9686
177	Q	H	0.4763
178	S	H	-0.0629
179	S	H	-0.3140
180	G	H	0.0978
181	L	H	0.1508
182	Y	H	0.6537
183	S	H	0.6529
184	L	H	0.0000
185	S	H	0.5595
186	S	H	0.0000
187	V	H	0.3476
188	V	H	0.0000
189	T	H	-0.2347
190	V	H	0.0000
191	P	H	-0.5819
192	S	H	-0.6815
193	S	H	-0.7692
194	S	H	-0.6767
195	L	H	-0.8483
196	G	H	-1.0913
197	T	H	-0.7781
198	Q	H	-1.3670
199	T	H	-1.2786
200	Y	H	0.0000
201	I	H	-1.3212
202	C	H	0.0000
203	N	H	-1.4105
204	V	H	0.0000
205	N	H	-1.6596
206	H	H	0.0000
207	K	H	-2.7670
208	P	H	-1.5673
209	S	H	-1.7392
210	N	H	-2.4647
211	T	H	-1.9667
212	K	H	-2.5860
213	V	H	-1.5808
214	D	H	-2.5497
215	K	H	-2.2083
216	R	H	-2.6323
217	V	H	0.0000
218	E	H	-2.8759
219	P	H	-1.8915
220	K	H	-2.2719
221	S	H	-1.2716