Project name: fenilananina hidroxilasa

Status: done

submitted: 2017-03-10 08:40:42, status changed: 2017-03-10 08:52:48
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Chain sequence(s) A: GQETSYIEDNSNQNGAISLIFSLKEEVGALAKVLRLFEENDINLTHIESRPSRLNKDEYEFFTYLDKRTKPVLGSIIKSLRNDIGATVHELSRDKEKNTVPWFPRTIQELDRFANQILDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYTEEEKQTWGTVFRTLKALYKTHACYEHNHIFPLLEKYCGFREDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKEGDSIKAYGAGLLSSFGELQYCLSDKPKLLPLELEKTACQEYSVTEFQPLYYVAESFSDAKEKVRTFAATIPRPFSVRYDPYTQRVEVLDNT
Distance of aggregation 10 Å
Dynamic mode No
Show buried residues

Minimal score value
-4.195
Maximal score value
1.8204
Average score
-0.9361
Total score value
-377.2348

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
19 G A -1.8038
20 Q A -2.4478
21 E A -2.2200
22 T A -1.3101
23 S A -0.4798
24 Y A -0.9434
25 I A -0.7267
26 E A -2.7015
27 D A -2.1217
28 N A -2.2683
29 S A -2.1298
30 N A -2.8301
31 Q A -2.4255
32 N A -1.9953
33 G A 0.0000
34 A A 0.0000
35 I A 0.0000
36 S A 0.0000
37 L A 0.0000
38 I A 0.0000
39 F A 0.0000
40 S A -1.0874
41 L A 0.0000
42 K A -3.1223
43 E A -3.4649
44 E A -2.4200
45 V A 0.0488
46 G A -0.7751
47 A A -1.3120
48 L A -0.8036
49 A A -0.9783
50 K A -2.0188
51 V A 0.0000
52 L A -1.7404
53 R A -3.2997
54 L A -2.4011
55 F A 0.0000
56 E A -4.1950
57 E A -4.0870
58 N A -2.8329
59 D A -3.1318
60 I A 0.0000
61 N A -2.2092
62 L A -1.2635
63 T A -0.5226
64 H A -0.7211
65 I A 0.0000
66 E A -0.5611
67 S A -0.8012
68 R A -1.7582
69 P A -1.9720
70 S A -1.5364
71 R A -0.8722
72 L A 0.1794
73 N A -1.9801
74 K A -3.2016
75 D A -3.9791
76 E A -3.1945
77 Y A -1.7973
78 E A 0.0000
79 F A 0.0000
80 F A 0.0000
81 T A 0.0000
82 Y A -0.2917
83 L A 0.0000
84 D A -1.5623
85 K A -2.3392
86 R A -2.6838
87 T A -2.0958
88 K A -2.2638
89 P A -1.2417
90 V A -0.7534
91 L A 0.0000
92 G A -1.2250
93 S A -1.2142
94 I A 0.0000
95 I A 0.0000
96 K A -3.2250
97 S A -2.6083
98 L A 0.0000
99 R A -3.5464
100 N A -3.5513
101 D A -3.2163
102 I A -2.0270
103 G A -2.2387
104 A A -1.6235
105 T A -0.7713
106 V A 0.0000
107 H A -0.4916
108 E A -0.7691
109 L A 0.0000
110 S A 0.0000
111 R A 0.0000
112 D A -2.1776
113 K A -2.2264
114 E A -2.4867
115 K A -2.8970
116 N A -2.4290
117 T A -1.7859
118 V A -1.0191
119 P A 0.0000
120 W A 0.0000
121 F A 0.0000
122 P A 0.0000
123 R A 0.0000
124 T A 0.0000
125 I A 0.0000
126 Q A -2.0356
127 E A 0.0000
128 L A 0.0000
129 D A -2.1847
130 R A -2.6312
131 F A 0.0000
132 A A 0.0000
133 N A -0.8672
134 Q A -0.4705
135 I A 1.2944
136 L A 1.8204
143 D A -2.5064
144 A A -1.8839
145 D A -2.5339
146 H A -1.9117
147 P A -1.4740
148 G A -1.6420
149 F A -1.7647
150 K A -2.2605
151 D A -1.2050
152 P A -0.6561
153 V A 0.4893
154 Y A 0.0000
155 R A -2.3661
156 A A -1.3696
157 R A -1.4036
158 R A -1.9434
159 K A -2.6171
160 Q A -1.9555
161 F A 0.0000
162 A A -1.1521
163 D A -1.4157
164 I A -1.0993
165 A A 0.0000
166 Y A -0.6994
167 N A -1.5410
168 Y A 0.0000
169 R A -2.4819
170 H A -1.8728
171 G A -1.6987
172 Q A -1.8111
173 P A -1.7532
174 I A 0.0000
175 P A -1.2777
176 R A -2.6711
177 V A 0.0000
178 E A -2.5507
179 Y A 0.0000
180 T A -2.3253
181 E A -3.7673
182 E A -3.4512
183 E A -2.8000
184 K A -3.5630
185 Q A -3.4082
186 T A 0.0000
187 W A 0.0000
188 G A 0.0000
189 T A -1.4364
190 V A 0.0000
191 F A 0.0000
192 R A -2.8988
193 T A -1.1992
194 L A 0.0000
195 K A -2.0119
196 A A -1.1099
197 L A -1.0220
198 Y A 0.0000
199 K A -1.8432
200 T A -1.0114
201 H A -0.6244
202 A A 0.0000
203 C A 0.0000
204 Y A 0.2998
205 E A -0.2975
206 H A 0.0000
207 N A -0.7233
208 H A -0.7418
209 I A 0.0000
210 F A 0.0000
211 P A -0.4457
212 L A 0.0646
213 L A 0.0000
214 E A -1.1175
215 K A -1.2058
216 Y A 0.3324
217 C A 0.0000
218 G A -1.4022
219 F A 0.0000
220 R A -3.6318
221 E A -4.1502
222 D A -4.0855
223 N A -2.8221
224 I A 0.0000
225 P A 0.0000
226 Q A -1.7106
227 L A 0.0000
228 E A -2.1274
229 D A -2.3468
230 V A 0.0000
231 S A 0.0000
232 Q A -2.1952
233 F A -0.9404
234 L A 0.0000
235 Q A -1.5007
236 T A -0.7851
237 C A -0.8243
238 T A 0.0000
239 G A -1.2641
240 F A 0.0000
241 R A -1.3836
242 L A 0.0000
243 R A 0.0000
244 P A 0.0000
245 V A 0.0000
246 A A 0.0243
247 G A 0.6581
248 L A 1.1544
249 L A 0.0000
250 S A 0.0000
251 S A 0.0000
252 R A 0.0000
253 D A -0.4440
254 F A 0.3552
255 L A 0.0000
256 G A 0.0000
257 G A 0.0000
258 L A 0.0000
259 A A 0.0000
260 F A 0.0000
261 R A -0.8364
262 V A 0.0000
263 F A 0.0000
264 H A 0.0000
265 C A 0.0000
266 T A 0.0000
267 Q A 0.0000
268 Y A 0.0000
269 I A 0.0000
270 R A 0.0000
271 H A -1.1123
272 G A -1.6045
273 S A -1.0002
274 K A -1.2741
275 P A -0.6572
276 M A 0.3022
277 Y A 0.1928
278 T A -0.1617
279 P A -0.7977
280 E A -0.3564
281 P A -0.1706
282 D A 0.0000
283 I A 0.0000
284 C A 0.0000
285 H A -0.1903
286 E A 0.0000
287 L A 0.0000
288 L A 0.0000
289 G A 0.0000
290 H A 0.0000
291 V A 0.0000
292 P A 0.0000
293 L A 0.0000
294 F A 0.0000
295 S A 0.0000
296 D A -1.4088
297 R A -2.1679
298 S A -1.4491
299 F A 0.0000
300 A A 0.0000
301 Q A -1.2956
302 F A 0.0000
303 S A 0.0000
304 Q A 0.0000
305 E A 0.0000
306 I A 0.0000
307 G A 0.0000
308 L A -0.5102
309 A A 0.0000
310 S A 0.0000
311 L A 0.0000
312 G A 0.0000
313 A A 0.0000
314 P A -1.4453
315 D A -2.7827
316 E A -2.9174
317 Y A -1.4990
318 I A 0.0000
319 E A -2.0839
320 K A -1.4002
321 L A 0.0000
322 A A 0.0000
323 T A 0.0000
324 I A 0.0000
325 Y A 0.0000
326 W A 0.0000
327 F A 0.0000
328 T A 0.0000
329 V A 0.0000
330 E A -0.2095
331 F A 0.0000
332 G A 0.0000
333 L A 0.0000
334 C A 0.0000
335 K A -2.9640
336 E A -2.8443
337 G A -2.5636
338 D A -2.6246
339 S A -1.7745
340 I A -1.3784
341 K A -0.7398
342 A A 0.0000
343 Y A 0.0000
344 G A 0.0000
345 A A 0.0000
346 G A 0.0000
347 L A 0.0000
348 L A 0.0000
349 S A 0.0000
350 S A -0.0658
351 F A -0.1047
352 G A -0.2831
353 E A 0.0000
354 L A 0.0000
355 Q A -0.6243
356 Y A -0.5996
357 C A 0.0000
358 L A -0.5330
359 S A -1.6449
360 D A -2.7371
361 K A -2.7198
362 P A -1.7239
363 K A -1.9865
364 L A -0.3775
365 L A -0.1738
366 P A -0.9016
367 L A 0.0000
368 E A -2.4583
369 L A 0.0000
370 E A -2.6955
371 K A -2.3322
372 T A 0.0000
373 A A 0.0000
374 C A -0.7167
375 Q A -1.2334
376 E A -2.0666
377 Y A 0.0000
378 S A -1.1299
379 V A 0.0350
380 T A -0.5896
381 E A -1.0433
382 F A 0.1893
383 Q A 0.0000
384 P A -0.7382
385 L A -0.6320
386 Y A 0.0000
387 Y A 0.0000
388 V A 0.0000
389 A A 0.0000
390 E A -2.9204
391 S A -2.1784
392 F A 0.0000
393 S A -1.9952
394 D A -2.8766
395 A A 0.0000
396 K A -2.4153
397 E A -3.3927
398 K A -2.8745
399 V A 0.0000
400 R A -2.8809
401 T A -1.6269
402 F A 0.0000
403 A A 0.0000
404 A A -0.7073
405 T A -0.3345
406 I A 0.0000
407 P A -0.5543
408 R A -0.8090
409 P A -0.9537
410 F A 0.0000
411 S A -1.3022
412 V A -1.0556
413 R A -1.7233
414 Y A 0.0000
415 D A 0.0000
416 P A -0.1423
417 Y A 0.9666
418 T A 0.0967
419 Q A -0.6199
420 R A -0.8010
421 V A 0.0000
422 E A -0.7427
423 V A -0.5972
424 L A -0.9051
425 D A -2.2716
426 N A -2.1180
427 T A -1.0779

 

Laboratory of Theory of Biopolymers 2015