Project name: 636539016c99809

Status: done

submitted: 2018-04-12 18:09:35, status changed: 2018-04-16 01:01:09
Settings
Chain sequence(s) A: NWYNDTYPLSPPQRTPAGIRYRIAVIADLDTESRAQEENTWFSYLKKGYLTLSDSGDKVAVEWDKDHGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVVYQIEGSKAVPWVILSDGDGTVEKGFKAEWLAVKDERLYVGGLGKEWTTTTGDVVNENPEWVKVVGYKGSVDHENWVSNYNALRAAAGIQPPGYLIHESACWSDTLQRWFFLLRRASQERYSEKDDERKGANLLLSASPDFGDIAVSHVGAVVPTHGFSSFKFIPNTDDQIIVALKSEEDSGRVASYIMAFTLDGRFLLPETKIGSVKYEGIEFI
Distance of aggregation 10 Å
Dynamic mode No
Show buried residues

Minimal score value
-4.0353
Maximal score value
2.0816
Average score
-0.805
Total score value
-255.1742

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
15 N A -0.9019
16 W A 0.1677
17 Y A -0.7555
18 N A -1.1985
19 D A -1.8447
20 T A -0.6784
21 Y A 0.3044
22 P A 0.0000
23 L A 0.2412
24 S A 0.0701
25 P A -0.4972
26 P A -0.9762
27 Q A -1.5243
28 R A -2.3220
29 T A -1.3522
30 P A -0.8859
31 A A -0.8580
32 G A 0.0000
33 I A -1.3525
34 R A -1.0528
35 Y A 0.0000
36 R A -0.6063
37 I A 0.0000
38 A A 0.0000
39 V A 0.0000
40 I A 0.0000
41 A A 0.0000
42 D A -0.4770
43 L A -1.0520
44 D A -1.6707
45 T A -1.8788
46 E A -2.6634
47 S A 0.0000
48 R A -3.8857
49 A A -3.2578
50 Q A -3.0778
51 E A -4.0008
52 E A -4.0353
53 N A -3.4190
54 T A 0.0000
55 W A 0.0000
56 F A -1.1363
57 S A 0.0000
58 Y A 0.0000
59 L A 0.0000
60 K A -1.4424
61 K A -1.8158
62 G A 0.0000
63 Y A -0.6874
64 L A 0.0000
65 T A -0.9192
66 L A -1.1413
67 S A -1.8253
68 D A -2.5823
69 S A -2.0042
70 G A -2.0772
71 D A -2.9580
72 K A -2.2877
73 V A 0.0000
74 A A -0.4961
75 V A -0.4510
76 E A -1.9106
77 W A -1.9244
78 D A -2.8607
79 K A -3.4084
80 D A -3.2801
81 H A -2.2177
82 G A -0.9864
83 V A -0.1342
84 L A 0.0000
85 E A -1.9323
86 S A -1.5751
87 H A -2.1320
88 L A -0.5776
89 A A -1.3150
90 E A -1.7531
91 K A -2.4708
92 G A -2.0660
93 R A -2.2556
94 G A 0.0000
95 M A 0.0000
96 E A 0.0000
97 L A 0.0000
98 S A 0.0000
99 D A 0.0000
100 L A 0.0000
101 I A 0.0000
102 V A 0.0000
103 F A 0.0000
104 N A -1.2368
105 G A -0.7849
106 K A -1.2429
107 L A 0.0000
108 Y A 0.0000
109 S A 0.0000
110 V A 0.0000
111 D A 0.0000
112 D A 0.0000
113 R A -1.3450
114 T A 0.0000
115 G A 0.0000
116 V A 0.0000
117 V A 0.0000
118 Y A 0.0000
119 Q A -0.8132
120 I A 0.0000
121 E A -2.7190
122 G A -1.9320
123 S A -1.7646
124 K A -2.6333
125 A A -1.3000
126 V A -0.2203
127 P A 0.5660
128 W A 0.5698
129 V A 0.0000
130 I A 2.0816
131 L A 0.0000
132 S A -0.8208
133 D A -1.2836
134 G A 0.0000
135 D A -2.0518
136 G A -1.4913
137 T A -1.0147
138 V A -1.3653
139 E A -2.3845
140 K A -2.5797
141 G A -1.1165
142 F A 0.0000
143 K A -0.9178
144 A A 0.0000
145 E A 0.0000
146 W A 0.0000
147 L A 0.0000
148 A A 0.0000
149 V A -1.0423
150 K A -2.2557
151 D A -3.0867
152 E A -2.8491
153 R A -2.3955
154 L A 0.0000
155 Y A 0.0000
156 V A 0.0000
157 G A 0.0000
158 G A 0.0000
159 L A 0.0843
160 G A 0.0000
161 K A 0.0000
162 E A 0.1062
163 W A 0.8355
164 T A 0.4749
165 T A 0.0603
166 T A -0.9819
167 T A -1.2611
168 G A 0.0000
169 D A -0.2962
170 V A 1.7881
171 V A 2.0044
172 N A 0.3716
173 E A -0.8094
174 N A -0.8702
175 P A 0.0000
176 E A 0.0000
177 W A -1.1290
178 V A 0.0000
179 K A 0.0000
180 V A 0.0000
181 V A 0.0000
182 G A -1.4911
183 Y A -1.0715
184 K A -1.6706
185 G A -0.7337
186 S A -0.7736
187 V A -0.4162
188 D A -1.9312
189 H A -1.9368
190 E A -1.9056
191 N A -1.9152
192 W A 0.0000
193 V A -0.6421
194 S A -0.5989
195 N A -0.9160
196 Y A 0.0000
197 N A -0.9423
198 A A -0.6648
199 L A 0.0000
200 R A -0.7962
201 A A -0.6992
202 A A -0.4006
203 A A -0.3113
204 G A -0.8636
205 I A 0.0000
206 Q A -2.1052
207 P A -1.8955
208 P A -2.1849
209 G A 0.0000
210 Y A 0.0000
211 L A 0.0000
212 I A 0.0000
213 H A 0.0000
214 E A 0.0000
215 S A 0.0000
216 A A 0.0000
217 C A 0.0000
218 W A -0.7985
219 S A 0.0000
220 D A -2.6428
221 T A -1.6557
222 L A -1.1327
223 Q A -1.7751
224 R A -1.4183
225 W A 0.0000
226 F A 0.0000
227 F A 0.0000
228 L A 0.0000
229 L A 0.0000
230 R A -0.3320
231 R A 0.0000
232 A A -0.9241
233 S A 0.0000
234 Q A -2.8475
235 E A -3.5492
236 R A -3.2373
237 Y A -2.1460
238 S A -2.6220
239 E A -3.4323
240 K A -3.5842
241 D A -3.5510
242 D A 0.0000
243 E A -3.1614
244 R A -3.0120
245 K A -1.9948
246 G A 0.0000
247 A A 0.0000
248 N A 0.0995
249 L A 0.0000
250 L A 0.0000
251 L A 0.0000
252 S A -0.2098
253 A A 0.0000
254 S A -1.5417
255 P A -1.6632
256 D A -2.3406
257 F A 0.0000
258 G A -1.8637
259 D A -2.1584
260 I A -0.7425
261 A A 0.0079
262 V A 0.2982
263 S A -0.6406
264 H A -1.1283
265 V A 0.0000
266 G A -0.6388
267 A A 0.6797
268 V A 1.5487
269 V A 0.9539
270 P A -0.4207
271 T A 0.0000
272 H A 0.0000
273 G A 0.0000
274 F A 0.0000
275 S A 0.0000
276 S A 0.0000
277 F A 0.0000
278 K A 0.0000
279 F A 0.0000
280 I A 0.0000
281 P A -1.0129
282 N A -1.9878
283 T A 0.0000
284 D A -2.8053
285 D A -2.0551
286 Q A -2.1848
287 I A 0.0000
288 I A 0.0000
289 V A 0.0000
290 A A 0.0000
291 L A 0.0000
292 K A 0.0000
293 S A 0.0000
294 E A -1.1233
295 E A -1.8428
296 D A 0.0000
297 S A -1.4584
298 G A -1.6851
299 R A -2.1836
300 V A -0.9449
301 A A 0.0000
302 S A 0.0000
303 Y A 0.0000
304 I A 0.0000
305 M A 0.0000
306 A A 0.0000
307 F A 0.0000
308 T A 0.0000
309 L A -1.4058
310 D A -2.5267
311 G A -1.9190
312 R A -2.2784
313 F A -1.0043
314 L A 0.0000
315 L A -0.6155
316 P A -0.9059
317 E A -1.1938
318 T A -1.2630
319 K A -1.9850
320 I A 0.0000
321 G A -0.5194
322 S A -0.6131
323 V A -0.0990
324 K A 0.0000
325 Y A 0.0000
326 E A 0.0000
327 G A 0.0000
328 I A 0.0000
329 E A 0.0000
330 F A 0.0000
331 I A 0.0000

 

Laboratory of Theory of Biopolymers 2015