Project name: 3N75 [mutate: KB437Y, KB440Y, EB445Y, DB470Y, KA437Y, KA440Y, EA445Y, DA470Y, KC437Y, KC440Y, EC445Y, DC470Y, KD437Y, KD440Y, ED445Y, DD470Y, KE437Y, KE440Y, EE445Y, DE470Y]

Status: done

submitted: 2017-09-13 11:39:31, status changed: 2017-09-13 13:49:59
Settings
Chain sequence(s) A: MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLKLIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISFFEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQKSPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTNGTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWFFDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRVKNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAFQKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKE
C: MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLKLIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISFFEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQKSPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTNGTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWFFDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRVKNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAFQKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKE
B: MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLKLIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISFFEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQKSPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTNGTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWFFDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRVKNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAFQKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKE
E: MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLKLIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISFFEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQKSPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTNGTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWFFDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRVKNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAFQKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKE
D: MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLKLIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISFFEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQKSPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTNGTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWFFDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRVKNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAFQKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKE
Distance of aggregation 10 Å
Dynamic mode No
Mutated residues KB437Y, KB440Y, EB445Y, DB470Y, KA437Y, KA440Y, EA445Y, DA470Y, KC437Y, KC440Y, EC445Y, DC470Y, KD437Y, KD440Y, ED445Y, DD470Y, KE437Y, KE440Y, EE445Y, DE470Y
Energy difference between WD and mutated (by FoldX) -5.1136 kcal/mol
Show buried residues

Minimal score value
-4.078
Maximal score value
2.8345
Average score
-0.6959
Total score value
-2470.4418

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
1 M A -0.3219
2 N A -1.1220
3 V A 0.0000
4 I A 0.0000
5 A A 0.0000
6 I A 0.0000
7 L A 0.0000
8 N A -1.3066
9 H A -1.4140
10 M A -0.6006
11 G A -0.6337
12 V A -0.6902
13 Y A -0.5278
14 F A 0.0000
15 K A 0.0000
16 E A -0.6554
17 E A -0.5920
18 P A 0.0000
19 I A -0.6954
20 R A -1.4210
21 E A -1.6176
22 L A 0.0000
23 H A -1.9910
24 R A -3.1509
25 A A 0.0000
26 L A 0.0000
27 E A -3.7431
28 R A -3.6233
29 L A -2.6501
30 N A -2.8253
31 F A 0.0000
32 Q A -1.4388
33 I A -0.7193
34 V A 0.0000
35 Y A 0.0835
36 P A 0.0000
37 N A -2.1346
38 D A -2.4019
39 R A -2.4279
40 D A -2.5580
41 D A 0.0000
42 L A 0.0000
43 L A -1.5511
44 K A -1.7422
45 L A 0.0000
46 I A 0.0000
47 E A -1.7945
48 N A -1.5649
49 N A 0.0000
50 A A -0.6863
51 R A -0.8911
52 L A 0.0000
53 C A 0.0000
54 G A 0.0000
55 V A 0.0000
56 I A 0.0000
57 F A 0.0000
58 D A 0.0000
59 W A 0.0000
60 D A -1.0630
61 K A -1.5101
62 Y A 0.0000
63 N A 0.0000
64 L A -0.4483
65 E A -1.9570
66 L A 0.0000
67 C A 0.0000
68 E A -2.2131
69 E A -2.0888
70 I A 0.0000
71 S A -2.1797
72 K A -2.7853
73 M A 0.0000
74 N A -1.7206
75 E A -1.7164
76 N A -0.8177
77 L A 0.0000
78 P A 0.0000
79 L A 0.0000
80 Y A 0.0000
81 A A 0.0000
82 F A 0.0000
83 A A 0.0000
84 N A -0.1933
85 T A 0.2092
86 Y A 0.9628
87 S A 0.0000
88 T A -0.0705
89 L A 0.0000
90 D A -0.4214
91 V A -0.4160
92 S A -0.5001
93 L A 0.0000
94 N A -1.8256
95 D A -2.6178
96 L A -2.4186
97 R A -2.9199
98 L A 0.0000
99 Q A -0.7666
100 I A -0.1440
101 S A -0.3496
102 F A 0.0000
103 F A 0.0000
104 E A -0.8202
105 Y A 0.0000
106 A A -0.7379
107 L A 0.0000
108 G A -1.2992
109 A A -1.4058
110 A A 0.0000
111 E A -3.7226
112 D A -3.6844
113 I A 0.0000
114 A A 0.0000
115 N A -3.7607
116 K A -3.8454
117 I A 0.0000
118 K A -3.5853
119 Q A -3.5829
120 T A -2.7097
121 T A 0.0000
122 D A -3.2236
123 E A -2.8616
124 Y A 0.0000
125 I A -0.5637
126 N A -0.8673
127 T A -0.3092
128 I A 0.6821
129 L A 0.7373
130 P A 0.0000
131 P A -0.7151
132 L A 0.0000
133 T A 0.0000
134 K A -0.0835
135 A A -0.5327
136 L A 0.0000
137 F A -0.4648
138 K A -1.3148
139 Y A -1.6550
140 V A 0.0000
141 R A -3.1488
142 E A -3.1326
143 G A -2.0622
144 K A -1.9195
145 Y A 0.5541
146 T A 0.9812
147 F A 2.1301
148 C A 1.3721
149 T A 0.4736
150 P A -0.2352
151 G A -0.1089
152 H A -0.3678
153 M A 0.3995
154 G A -0.7604
155 G A 0.0000
156 T A -0.6512
157 A A -0.6477
158 F A -0.0511
159 Q A -1.2456
160 K A -1.9004
161 S A -0.2891
162 P A 0.5360
163 V A 1.9647
164 G A 0.0000
165 S A 0.7672
166 L A 2.6177
167 F A 2.6713
168 Y A 1.3449
169 D A 0.5236
170 F A 2.4346
171 F A 1.8087
172 G A 0.2705
173 P A -0.9238
174 N A -1.6993
175 T A -0.5686
176 M A 0.0000
177 K A -1.5223
178 S A -1.1520
179 D A -1.0549
180 I A 0.0000
181 S A 0.5894
182 I A 1.6041
183 S A 0.8983
184 V A 0.0000
185 S A -0.5355
186 E A -1.5268
187 L A 0.0000
188 G A -1.1529
189 S A -0.7277
190 L A 0.0000
191 L A -0.7762
192 D A -2.0300
193 H A -1.9317
194 S A -2.0389
195 G A -2.0040
196 P A -1.9511
197 H A 0.0000
198 K A -3.2812
199 E A -3.0647
200 A A 0.0000
201 E A 0.0000
202 Q A -3.0464
203 Y A -2.0082
204 I A 0.0000
205 A A 0.0000
206 R A -2.6883
207 V A 0.0000
208 F A 0.0000
209 N A -1.6115
210 A A -1.9686
211 D A -2.4320
212 R A -2.9869
213 S A 0.0000
214 Y A 0.0000
215 M A 0.0000
216 V A 0.0000
217 T A 0.0000
218 N A -1.7047
219 G A -1.1951
220 T A 0.0000
221 S A -0.8404
222 T A 0.0000
223 A A 0.0000
224 N A 0.0000
225 K A 0.0184
226 I A 0.0000
227 V A 0.0000
228 G A 0.0000
229 M A 0.2523
230 Y A -0.1209
231 S A 0.0109
232 A A 0.0000
233 P A -0.4167
234 A A -0.6812
235 G A -0.9969
236 S A 0.0000
237 T A 0.0000
238 I A 0.0000
239 L A 0.0000
240 I A 0.0000
241 D A 0.0000
242 R A 0.0000
243 N A -0.6864
244 C A 0.0000
245 H A -1.4207
246 K A -1.2780
247 S A 0.0000
248 L A 0.0000
249 T A 0.0000
250 H A -0.4201
251 L A 0.0000
252 M A 0.0000
253 M A 0.2781
254 M A 0.4499
255 S A -0.2377
256 D A -0.9601
257 V A 0.0000
258 T A 0.0000
259 P A 0.0000
260 I A 0.0000
261 Y A 0.0000
262 F A 0.0000
263 R A -1.5842
264 P A 0.0000
265 T A -0.6403
266 R A 0.0000
267 N A 0.0000
268 A A -0.8921
269 Y A -0.0620
270 G A -0.1277
271 I A 0.0000
272 L A 0.0000
273 G A 0.0000
274 G A 0.0000
275 I A 0.0000
276 P A -0.9487
277 Q A -0.6673
278 S A -0.9636
279 E A -1.0025
280 F A 0.0000
281 Q A -1.6149
282 H A -1.7288
283 A A -1.0858
284 T A -1.1537
285 I A 0.0000
286 A A -1.7829
287 K A -2.9383
288 R A -2.1913
289 V A -2.0217
290 K A -3.3465
291 E A -3.3217
292 T A -2.0650
293 P A -1.4618
294 N A -1.8892
295 A A -1.3256
296 T A -0.5052
297 W A 0.0594
298 P A 0.0000
299 V A -0.2932
300 H A 0.0000
301 A A 0.0000
302 V A 0.0000
303 I A 0.0000
304 T A -0.1102
305 N A 0.0000
306 S A 0.0000
307 T A 0.0000
308 Y A 0.2736
309 D A 0.0000
310 G A 0.0000
311 L A 0.0000
312 L A 0.0000
313 Y A 0.0000
314 N A -1.4579
315 T A 0.0000
316 D A -2.4664
317 F A -1.4707
318 I A 0.0000
319 K A 0.0000
320 K A -2.4779
321 T A -1.6877
322 L A 0.0000
323 D A -2.1104
324 V A 0.0000
325 K A -2.2667
326 S A 0.0000
327 I A 0.0000
328 H A 0.0000
329 F A 0.0000
330 D A 0.0000
331 S A 0.0000
332 A A -0.0039
333 W A 0.3626
334 V A 0.0000
335 P A 0.0000
336 Y A 0.0000
337 T A 0.0000
338 N A -1.0707
339 F A 0.0000
340 S A 0.0000
341 P A -1.2051
342 I A -0.8999
343 Y A 0.0000
344 E A -2.3496
345 G A -1.7342
346 K A -1.3002
347 C A 0.0000
348 G A 0.0000
349 M A 0.0000
350 S A -1.6545
351 G A -1.7328
352 G A -1.7706
353 R A -2.6914
354 V A -2.4592
355 E A -3.0382
356 G A -2.3995
357 K A -2.2830
358 V A -1.4294
359 I A 0.0000
360 Y A 0.0000
361 E A 0.0000
362 T A 0.0000
363 Q A 0.0000
364 S A -0.2974
365 T A 0.0000
366 H A -0.3092
368 L A 0.0509
369 L A 0.0000
370 A A 0.2498
371 A A 0.5434
372 F A 1.4622
373 S A -0.0392
374 Q A -1.0638
375 A A 0.0000
376 S A 0.0000
377 M A 0.0000
378 I A 0.0000
379 H A 0.0000
380 V A 0.0000
381 K A 0.0000
382 G A 0.0000
383 D A -2.9724
384 V A -2.3343
385 N A -3.0400
386 E A -4.0780
387 E A -3.6374
388 T A -2.4609
389 F A 0.0000
390 N A -2.2662
391 E A -2.1001
392 A A 0.0000
393 Y A 0.0000
394 M A 0.1037
395 M A 0.6763
396 H A 0.0360
397 T A -0.0679
398 T A -0.1545
399 T A 0.1942
400 S A -0.0600
401 P A 0.0000
402 H A -0.9183
403 Y A 0.0000
404 G A 0.0936
405 I A 0.1188
406 V A 0.0000
407 A A 0.0000
408 S A 0.0000
409 T A 0.0000
410 E A 0.0000
411 T A 0.1007
412 A A 0.0000
413 A A 0.0000
414 A A 0.0969
415 M A 0.0581
416 M A 0.0000
417 K A -1.5490
418 G A -1.4992
419 N A -2.1355
420 A A -1.6145
421 G A 0.0000
422 K A -2.6465
423 R A -2.5771
424 L A -1.1189
425 I A 0.0000
426 N A -2.0205
427 G A -1.5520
428 S A 0.0000
429 I A 0.0000
430 E A -2.1693
431 R A -1.1459
432 A A 0.0000
433 I A -0.4694
434 K A -0.1660
435 F A 0.0000
436 R A 0.0000
437 Y A 0.8778 mutated: KA437Y
438 E A 0.0000
439 I A 0.0000
440 Y A 0.1764 mutated: KA440Y
441 R A 0.2030
442 L A 0.0000
443 R A -0.7499
444 T A -0.1512
445 Y A 0.5222 mutated: EA445Y
446 S A -0.7756
447 D A -1.8146
448 G A -1.3914
449 W A -0.7647
450 F A 0.0000
451 F A 0.0000
452 D A -0.4703
453 V A 0.0000
454 W A 0.0000
455 Q A 0.0000
456 P A -1.5305
457 D A -2.3892
458 H A -2.1776
459 I A -1.4676
460 D A -2.1570
461 T A -1.2664
462 T A -1.1393
463 E A -1.0265
464 C A 0.0000
465 W A 0.0000
466 P A -1.2410
467 L A 0.0000
468 R A -2.0448
469 S A -1.4603
470 Y A 0.4905 mutated: DA470Y
471 S A -0.4032
472 T A -1.0855
473 W A -0.7061
474 H A 0.0000
475 G A -1.5308
476 F A 0.0000
477 K A -2.4805
478 N A -2.3648
479 I A -1.9579
480 D A -2.2385
481 N A -2.5284
482 E A -2.6514
483 H A 0.0000
484 M A 0.0000
485 Y A 0.0000
486 L A 0.0000
487 D A 0.0000
488 P A 0.0000
489 I A 0.0000
490 K A 0.0000
491 V A 0.0000
492 T A 0.0000
493 L A 0.0000
494 L A 0.0388
495 T A 0.0000
496 P A -0.2440
497 G A 0.0000
498 M A -1.4340
499 E A -3.2797
500 K A -3.4592
501 D A -3.3172
502 G A -2.3929
503 T A -1.9129
504 M A -1.1420
505 S A -1.1933
506 D A -1.6877
507 F A -0.2926
508 G A 0.0000
509 I A 0.0000
510 P A 0.0000
511 A A 0.0000
512 S A -0.1059
513 I A 0.0000
514 V A 0.0000
515 A A -0.5689
516 K A -1.0389
517 Y A 0.0000
518 L A 0.0000
519 D A -2.0023
520 E A -1.8391
521 H A -1.7855
522 G A -1.1784
523 I A -0.3696
524 V A 0.8526
525 V A 0.2041
526 E A -0.5099
527 K A -0.3858
528 T A -0.2995
529 G A -0.0083
530 P A 0.0000
531 Y A 0.0000
532 N A 0.0000
533 L A 0.0000
534 L A 0.0000
535 F A 0.0000
536 L A 0.1550
537 F A 0.0000
538 S A 0.2095
539 I A 0.2377
540 G A -0.2142
541 I A -0.2258
542 D A -0.9996
543 K A -0.8991
544 T A -0.9975
545 K A -1.3481
546 A A 0.0000
547 L A 0.0000
548 S A -0.5960
549 L A 0.0000
550 L A 0.0000
551 R A 0.0000
552 A A 0.0000
553 L A 0.0000
554 T A 0.0000
555 D A -0.9676
556 F A 0.0000
557 K A 0.0000
558 R A -1.2659
559 A A 0.0000
560 F A 0.0000
561 D A -0.9460
562 L A 0.3975
563 N A -0.5463
564 L A -0.6792
565 R A -2.0855
566 V A 0.0000
567 K A -2.4157
568 N A -2.0058
569 M A 0.0000
570 L A 0.0000
571 P A -1.7332
572 S A -1.9808
573 L A 0.0000
574 Y A -2.6032
575 R A -3.3528
576 E A -3.1958
577 D A -2.5510
578 P A -2.6124
579 E A -2.5073
580 F A -1.0719
581 Y A 0.0000
582 E A -2.4687
583 N A -2.1795
584 M A -1.8076
585 R A -2.1573
586 I A 0.0000
587 Q A -1.8156
588 E A -2.2988
589 L A 0.0000
590 A A 0.0000
591 Q A -2.1682
592 N A -1.6535
593 I A -0.8315
594 H A 0.0000
595 K A -1.2589
596 L A -0.8687
597 I A 0.0000
598 V A -0.7777
599 H A -1.0853
600 H A -1.2926
601 N A -1.5064
602 L A 0.0000
603 P A 0.0000
604 D A -2.2330
605 L A -1.5751
606 M A 0.0000
607 Y A -1.0107
608 R A -2.2340
609 A A 0.0000
610 F A -0.4044
611 E A -0.8186
612 V A -0.3786
613 L A 0.3022
614 P A 0.0000
615 T A 0.3582
616 M A 0.7980
617 V A 1.1535
618 M A 0.8168
619 T A 0.2795
620 P A 0.0000
621 Y A 0.0355
622 A A 0.0697
623 A A 0.0000
624 F A 0.1954
625 Q A -0.3517
626 K A -1.1408
627 E A -0.9618
628 L A 0.3774
629 H A -0.8893
630 G A -1.0019
631 M A -1.2631
632 T A -1.7759
633 E A -2.3685
634 E A -2.1949
635 V A -1.5175
636 Y A -1.6097
637 L A 0.0000
638 D A -2.7579
639 E A -2.4714
640 M A 0.0000
641 V A -1.0274
642 G A -0.6782
643 R A -0.7705
644 I A -0.0934
645 N A 0.0000
646 A A 0.0000
647 N A -0.4989
648 M A 0.0000
649 I A 0.0000
650 L A -0.4273
651 P A 0.0000
652 Y A -0.0484
653 P A 0.0521
654 P A 0.0000
655 G A -0.1171
656 V A 0.0000
657 P A 0.0000
658 L A 0.0000
659 V A 0.0000
660 M A 0.0000
661 P A 0.0000
662 G A 0.0000
663 E A 0.0000
664 M A 0.5741
665 I A 0.0000
666 T A -1.5613
667 E A -2.9020
668 E A -2.7149
669 S A 0.0000
670 R A -2.0574
671 P A -1.6143
672 V A 0.0000
673 L A 0.0000
674 E A -1.7454
675 F A 0.0000
676 L A 0.0000
677 Q A -1.5777
678 M A 0.0000
679 L A 0.0000
680 C A -1.9388
681 E A -2.2178
682 I A -1.0607
683 G A -1.4510
684 A A -1.2667
685 H A -0.9933
686 Y A -0.3978
687 P A -1.0536
688 G A -1.2489
689 F A -0.9004
690 E A -2.2524
691 T A -2.0527
692 D A -2.2445
693 I A 0.0000
694 H A -1.1926
695 G A -0.7017
696 A A -1.0892
697 Y A -1.1622
698 R A -2.7025
699 Q A -2.4073
700 A A -1.8333
701 D A -2.8548
702 G A -2.7461
703 R A -3.0534
704 Y A 0.0000
705 T A 0.0000
706 V A 0.0000
707 K A -1.4932
708 V A 0.0000
709 L A 0.0000
710 K A -3.0916
711 E A -2.6402
1 M B -0.1482
2 N B -1.0343
3 V B 0.0000
4 I B 0.0000
5 A B 0.0000
6 I B 0.0000
7 L B 0.0000
8 N B -1.2728
9 H B -1.3813
10 M B -0.5433
11 G B -0.5834
12 V B -0.6447
13 Y B -0.4692
14 F B 0.0000
15 K B 0.0000
16 E B -0.6116
17 E B -0.5735
18 P B 0.0000
19 I B -0.7207
20 R B -1.4732
21 E B -1.6706
22 L B 0.0000
23 H B -2.1114
24 R B -3.3785
25 A B 0.0000
26 L B 0.0000
27 E B -3.7702
28 R B -3.5769
29 L B -2.4112
30 N B -2.7561
31 F B 0.0000
32 Q B -1.4120
33 I B 0.0000
34 V B 0.0000
35 Y B -0.0165
36 P B 0.0000
37 N B -2.2359
38 D B -2.5887
39 R B -2.5292
40 D B -2.7189
41 D B 0.0000
42 L B 0.0000
43 L B -1.7704
44 K B -2.0533
45 L B 0.0000
46 I B 0.0000
47 E B -2.3765
48 N B -1.8072
49 N B 0.0000
50 A B -0.8258
51 R B -0.8453
52 L B 0.0000
53 C B 0.0000
54 G B 0.0000
55 V B 0.0000
56 I B 0.0000
57 F B 0.0000
58 D B 0.0000
59 W B 0.0000
60 D B -1.1671
61 K B -1.4105
62 Y B 0.0000
63 N B 0.0000
64 L B 0.0276
65 E B -1.6189
66 L B 0.0000
67 C B 0.0000
68 E B -2.6197
69 E B -2.1863
70 I B 0.0000
71 S B 0.0000
72 K B -2.7191
73 M B 0.0000
74 N B -1.6561
75 E B -1.7782
76 N B -1.0198
77 L B 0.0000
78 P B 0.0000
79 L B 0.0000
80 Y B 0.0000
81 A B 0.0000
82 F B 0.0000
83 A B 0.0000
84 N B -0.1313
85 T B 0.2178
86 Y B 0.9237
87 S B 0.0000
88 T B -0.0706
89 L B 0.0000
90 D B -0.1432
91 V B -0.0899
92 S B -0.3087
93 L B 0.0000
94 N B -1.4955
95 D B -2.4507
96 L B -2.3737
97 R B -2.6987
98 L B 0.0000
99 Q B -0.9399
100 I B -0.2218
101 S B -0.3401
102 F B 0.0000
103 F B 0.0000
104 E B -0.7691
105 Y B 0.0000
106 A B -0.6390
107 L B 0.0000
108 G B -1.2141
109 A B -1.3700
110 A B 0.0000
111 E B -3.5755
112 D B -3.4621
113 I B 0.0000
114 A B 0.0000
115 N B -3.1615
116 K B -3.4229
117 I B 0.0000
118 K B -3.3154
119 Q B -3.4144
120 T B -2.6435
121 T B 0.0000
122 D B -3.2267
123 E B -2.9995
124 Y B 0.0000
125 I B -0.6427
126 N B -0.9615
127 T B -0.4235
128 I B 0.5213
129 L B 0.6769
130 P B 0.0000
131 P B -0.6866
132 L B 0.0000
133 T B 0.0000
134 K B -0.0948
135 A B -0.5559
136 L B 0.0000
137 F B -0.4855
138 K B -1.3798
139 Y B -1.7151
140 V B -2.0158
141 R B -3.1406
142 E B -3.1489
143 G B -2.2122
144 K B -2.0764
145 Y B 0.2585
146 T B 0.8517
147 F B 2.0879
148 C B 1.3128
149 T B 0.4394
150 P B -0.2805
151 G B -0.0994
152 H B -0.3755
153 M B 0.3490
154 G B -0.8034
155 G B 0.0000
156 T B -0.6653
157 A B -0.6611
158 F B -0.0817
159 Q B -1.2928
160 K B -1.9311
161 S B -0.3040
162 P B 0.5502
163 V B 1.9698
164 G B 1.1711
165 S B 0.7665
166 L B 2.6643
167 F B 2.7696
168 Y B 1.3651
169 D B 0.5163
170 F B 2.4437
171 F B 1.7826
172 G B 0.2187
173 P B -0.9825
174 N B -1.7155
175 T B -0.5777
176 M B 0.0000
177 K B -1.6078
178 S B -1.1503
179 D B -1.0053
180 I B 0.0000
181 S B 0.0000
182 I B 1.2958
183 S B 0.6893
184 V B 0.0000
185 S B -0.7259
186 E B -1.7452
187 L B 0.0000
188 G B -1.2636
189 S B -0.8088
190 L B 0.0000
191 L B -0.6428
192 D B -2.0247
193 H B -1.8981
194 S B -2.0120
195 G B -2.0044
196 P B -1.9126
197 H B 0.0000
198 K B -3.2627
199 E B -2.9926
200 A B 0.0000
201 E B 0.0000
202 Q B -3.0343
203 Y B -1.9791
204 I B 0.0000
205 A B 0.0000
206 R B -2.7577
207 V B 0.0000
208 F B 0.0000
209 N B -1.8982
210 A B -2.1171
211 D B -2.5048
212 R B -3.0251
213 S B 0.0000
214 Y B 0.0000
215 M B 0.0000
216 V B 0.0000
217 T B 0.0000
218 N B -1.6968
219 G B 0.0000
220 T B 0.0000
221 S B -0.7839
222 T B 0.0000
223 A B 0.0000
224 N B 0.0000
225 K B 0.0270
226 I B 0.0000
227 V B 0.0000
228 G B 0.0000
229 M B 0.2541
230 Y B -0.1321
231 S B -0.0125
232 A B 0.0000
233 P B -0.4540
234 A B -0.7844
235 G B -1.0897
236 S B 0.0000
237 T B 0.0000
238 I B 0.0000
239 L B 0.0000
240 I B 0.0000
241 D B 0.0000
242 R B 0.0000
243 N B -0.4813
244 C B 0.0000
245 H B -1.0805
246 K B -1.1642
247 S B 0.0000
248 L B 0.0000
249 T B 0.0000
250 H B -0.3642
251 L B 0.0000
252 M B 0.0000
253 M B 0.3037
254 M B 0.5005
255 S B 0.0000
256 D B -1.2057
257 V B 0.0000
258 T B 0.0000
259 P B 0.0000
260 I B 0.0000
261 Y B 0.0000
262 F B 0.0000
263 R B -0.9891
264 P B -0.6913
265 T B -0.6717
266 R B 0.0000
267 N B 0.0000
268 A B -0.7799
269 Y B 0.0169
270 G B -0.0968
271 I B 0.0000
272 L B 0.0000
273 G B 0.0000
274 G B 0.0000
275 I B 0.0000
276 P B -0.8254
277 Q B -0.8564
278 S B -0.8820
279 E B -0.8651
280 F B 0.0000
281 Q B -1.4522
282 H B -1.7524
283 A B -1.1014
284 T B -1.1771
285 I B 0.0000
286 A B -1.8462
287 K B -2.9961
288 R B -2.2883
289 V B 0.0000
290 K B -3.4390
291 E B -3.3847
292 T B -2.1373
293 P B -1.4973
294 N B -1.9189
295 A B -1.3765
296 T B -0.5495
297 W B 0.0078
298 P B 0.0000
299 V B -0.2717
300 H B 0.0000
301 A B 0.0000
302 V B 0.0000
303 I B 0.0000
304 T B 0.0000
305 N B 0.0000
306 S B 0.0000
307 T B 0.0000
308 Y B 0.2552
309 D B 0.0000
310 G B 0.0000
311 L B 0.0000
312 L B 0.0000
313 Y B 0.0000
314 N B -1.4075
315 T B 0.0000
316 D B -2.4661
317 F B -1.5188
318 I B 0.0000
319 K B 0.0000
320 K B -2.4463
321 T B -1.7302
322 L B 0.0000
323 D B -2.2253
324 V B 0.0000
325 K B -2.3283
326 S B 0.0000
327 I B 0.0000
328 H B 0.0000
329 F B 0.0000
330 D B 0.0000
331 S B 0.0000
332 A B 0.0118
333 W B 0.2813
334 V B 0.0000
335 P B 0.0000
336 Y B 0.0000
337 T B 0.0000
338 N B -1.1810
339 F B 0.0000
340 S B 0.0000
341 P B -1.3938
342 I B 0.0000
343 Y B 0.0000
344 E B -2.3697
345 G B -1.6940
346 K B 0.0000
347 C B 0.0000
348 G B 0.0000
349 M B 0.0000
350 S B -1.6949
351 G B -1.7822
352 G B -1.8775
353 R B -2.8691
354 V B -2.5609
355 E B -3.1027
356 G B -2.4652
357 K B -2.4075
358 V B 0.0000
359 I B 0.0000
360 Y B 0.0000
361 E B 0.0000
362 T B 0.0000
363 Q B 0.0000
364 S B -0.3082
365 T B 0.0000
366 H B -0.1211
368 L B 0.1276
369 L B 0.0000
370 A B 0.3223
371 A B 0.6169
372 F B 1.5148
373 S B 0.0052
374 Q B -1.0462
375 A B 0.0000
376 S B 0.0000
377 M B 0.0000
378 I B 0.0000
379 H B 0.0000
380 V B 0.0000
381 K B 0.0000
382 G B 0.0000
383 D B -3.0561
384 V B -2.3927
385 N B -3.0570
386 E B -4.0664
387 E B -3.6217
388 T B -2.4807
389 F B 0.0000
390 N B -2.3213
391 E B -2.1412
392 A B 0.0000
393 Y B 0.0000
394 M B 0.0129
395 M B 0.6351
396 H B 0.0093
397 T B -0.1189
398 T B -0.1550
399 T B 0.1546
400 S B -0.1050
401 P B 0.0000
402 H B -0.9196
403 Y B 0.0000
404 G B 0.1052
405 I B 0.1387
406 V B 0.0000
407 A B 0.0000
408 S B 0.0000
409 T B 0.0000
410 E B 0.0000
411 T B 0.1268
412 A B 0.0000
413 A B 0.0000
414 A B 0.1588
415 M B 0.2031
416 M B 0.0000
417 K B -1.2048
418 G B -1.1835
419 N B -1.5441
420 A B -1.2974
421 G B 0.0000
422 K B -2.1173
423 R B -1.9844
424 L B -0.7486
425 I B 0.0000
426 N B -1.8659
427 G B -1.4022
428 S B 0.0000
429 I B 0.0000
430 E B -2.1954
431 R B -1.2060
432 A B 0.0000
433 I B -0.4803
434 K B -0.2083
435 F B 0.0000
436 R B 0.0000
437 Y B 0.8638 mutated: KB437Y
438 E B 0.0000
439 I B 0.0000
440 Y B 0.0051 mutated: KB440Y
441 R B 0.1741
442 L B 0.0000
443 R B -0.8606
444 T B -0.2186
445 Y B 0.4966 mutated: EB445Y
446 S B -0.8127
447 D B -1.8144
448 G B -1.4173
449 W B -0.7862
450 F B 0.0000
451 F B 0.0000
452 D B -0.4921
453 V B 0.0000
454 W B 0.0000
455 Q B 0.0000
456 P B 0.0000
457 D B -2.3830
458 H B -2.1268
459 I B -1.5593
460 D B -2.2216
461 T B -1.4471
462 T B -1.5187
463 E B -1.8057
464 C B 0.0000
465 W B 0.0000
466 P B -1.2657
467 L B 0.0000
468 R B -1.7479
469 S B -1.2981
470 Y B 0.5797 mutated: DB470Y
471 S B -0.2769
472 T B -0.9510
473 W B -0.5937
474 H B 0.0000
475 G B -1.2228
476 F B 0.0000
477 K B -2.3981
478 N B -2.2819
479 I B -1.8635
480 D B -2.1492
481 N B -2.3387
482 E B -2.5775
483 H B 0.0000
484 M B 0.0000
485 Y B 0.0000
486 L B 0.0000
487 D B 0.0000
488 P B 0.0000
489 I B 0.0000
490 K B 0.0000
491 V B 0.0000
492 T B 0.0000
493 L B 0.0000
494 L B 0.0409
495 T B 0.0000
496 P B -0.2260
497 G B 0.0000
498 M B -1.4370
499 E B -3.2361
500 K B -3.3771
501 D B -3.2519
502 G B -2.1968
503 T B -1.7800
504 M B -1.3674
505 S B -1.4942
506 D B -1.8644
507 F B -0.3968
508 G B 0.0000
509 I B 0.0000
510 P B 0.0000
511 A B 0.0000
512 S B -0.1907
513 I B 0.0000
514 V B 0.0000
515 A B -0.5071
516 K B -1.0842
517 Y B 0.0000
518 L B 0.0000
519 D B -2.0305
520 E B -1.8323
521 H B -1.7780
522 G B -1.1721
523 I B -0.3354
524 V B 0.8218
525 V B 0.1353
526 E B -0.5807
527 K B -0.4003
528 T B -0.2858
529 G B 0.0157
530 P B 0.0700
531 Y B 0.0000
532 N B 0.0000
533 L B 0.0000
534 L B 0.0000
535 F B 0.0000
536 L B 0.1948
537 F B 0.0000
538 S B 0.2375
539 I B 0.2548
540 G B -0.1921
541 I B -0.2047
542 D B -1.0577
543 K B -0.8729
544 T B -0.9378
545 K B -1.2326
546 A B 0.0000
547 L B 0.0000
548 S B -0.5368
549 L B 0.0000
550 L B 0.0000
551 R B 0.0000
552 A B 0.0000
553 L B 0.0000
554 T B 0.0000
555 D B -1.3162
556 F B 0.0000
557 K B 0.0000
558 R B -1.5549
559 A B 0.0000
560 F B 0.0000
561 D B -1.3646
562 L B -0.2168
563 N B -0.7629
564 L B -0.7380
565 R B -1.8291
566 V B 0.0000
567 K B -2.2134
568 N B -1.8691
569 M B 0.0000
570 L B 0.0000
571 P B -1.6375
572 S B -1.9496
573 L B 0.0000
574 Y B -2.3435
575 R B -3.2630
576 E B -3.1567
577 D B -2.4461
578 P B -2.4970
579 E B -2.4310
580 F B -0.9959
581 Y B 0.0000
582 E B -2.2631
583 N B -2.0418
584 M B -1.6018
585 R B -1.9537
586 I B 0.0000
587 Q B -1.7356
588 E B -2.0576
589 L B 0.0000
590 A B 0.0000
591 Q B -2.3785
592 N B -1.9003
593 I B 0.0000
594 H B 0.0000
595 K B -2.5471
596 L B -1.6064
597 I B 0.0000
598 V B -1.5563
599 H B -1.7050
600 H B -1.6585
601 N B -2.0091
602 L B 0.0000
603 P B 0.0000
604 D B -1.8205
605 L B -1.2943
606 M B 0.0000
607 Y B -0.9478
608 R B -1.9950
609 A B 0.0000
610 F B 0.0000
611 E B -1.5279
612 V B -0.6212
613 L B 0.1085
614 P B 0.0000
615 T B 0.3535
616 M B 0.8078
617 V B 1.1079
618 M B 0.8320
619 T B 0.2411
620 P B 0.0000
621 Y B 0.0539
622 A B 0.0992
623 A B 0.0000
624 F B 0.3332
625 Q B -0.1742
626 K B -0.9659
627 E B -0.6864
628 L B 0.5167
629 H B -0.7585
630 G B -0.7851
631 M B -1.0004
632 T B -1.5528
633 E B -2.2545
634 E B -2.2368
635 V B -1.5503
636 Y B -1.2201
637 L B 0.0000
638 D B -2.0109
639 E B -2.1314
640 M B 0.0000
641 V B -0.9547
642 G B -0.6296
643 R B -0.7358
644 I B -0.0512
645 N B 0.0000
646 A B 0.0000
647 N B -0.5220
648 M B 0.0000
649 I B 0.0000
650 L B -0.4243
651 P B 0.0000
652 Y B 0.0575
653 P B 0.1177
654 P B 0.0000
655 G B -0.0731
656 V B 0.0000
657 P B 0.0000
658 L B 0.0000
659 V B 0.0000
660 M B 0.0000
661 P B 0.0000
662 G B 0.0000
663 E B 0.0000
664 M B 0.5437
665 I B 0.0000
666 T B -1.6257
667 E B -2.9738
668 E B -2.7588
669 S B 0.0000
670 R B -2.1495
671 P B -1.6737
672 V B 0.0000
673 L B 0.0000
674 E B -1.5985
675 F B 0.0000
676 L B 0.0000
677 Q B -1.3787
678 M B 0.0000
679 L B 0.0000
680 C B -1.9378
681 E B -2.1342
682 I B -1.0367
683 G B -1.3387
684 A B -1.1504
685 H B -0.9327
686 Y B -0.3357
687 P B -0.7757
688 G B -1.1459
689 F B -0.7813
690 E B -1.9194
691 T B -1.8971
692 D B -2.1778
693 I B 0.0000
694 H B -1.1934
695 G B -0.9060
696 A B -1.0563
697 Y B -1.0860
698 R B -2.5550
699 Q B -2.1829
700 A B -1.7245
701 D B -2.7314
702 G B -2.5362
703 R B -2.4881
704 Y B 0.0000
705 T B 0.0000
706 V B 0.0000
707 K B -1.5139
708 V B 0.0000
709 L B 0.0000
710 K B -2.6339
711 E B -2.4301
1 M C -0.5055
2 N C -1.2147
3 V C 0.0000
4 I C 0.0000
5 A C 0.0000
6 I C 0.0000
7 L C 0.0000
8 N C -1.2607
9 H C -1.3880
10 M C -0.5757
11 G C -0.5705
12 V C -0.6384
13 Y C -0.4900
14 F C 0.0000
15 K C 0.0000
16 E C -0.6432
17 E C -0.6422
18 P C 0.0000
19 I C -0.7893
20 R C -1.5875
21 E C -1.7354
22 L C 0.0000
23 H C -2.2944
24 R C -3.3322
25 A C 0.0000
26 L C 0.0000
27 E C -3.6435
28 R C -3.5149
29 L C -2.3353
30 N C -2.6841
31 F C 0.0000
32 Q C -1.4358
33 I C 0.0000
34 V C 0.0000
35 Y C 0.0238
36 P C 0.0000
37 N C -2.1640
38 D C -2.4818
39 R C -2.4357
40 D C -2.5970
41 D C 0.0000
42 L C 0.0000
43 L C -1.5746
44 K C -1.8681
45 L C 0.0000
46 I C 0.0000
47 E C -1.8977
48 N C -1.6752
49 N C 0.0000
50 A C -1.0549
51 R C -1.5380
52 L C 0.0000
53 C C 0.0000
54 G C 0.0000
55 V C 0.0000
56 I C 0.0000
57 F C 0.0000
58 D C 0.0000
59 W C 0.0000
60 D C -1.8084
61 K C -1.9110
62 Y C -1.2406
63 N C 0.0000
64 L C -0.3174
65 E C -2.0530
66 L C 0.0000
67 C C 0.0000
68 E C -2.9658
69 E C -2.2865
70 I C 0.0000
71 S C -2.2629
72 K C -2.8207
73 M C -1.9943
74 N C -1.5273
75 E C -1.5943
76 N C -0.6740
77 L C 0.0000
78 P C 0.0000
79 L C 0.0000
80 Y C 0.0000
81 A C 0.0000
82 F C 0.0000
83 A C 0.0000
84 N C -0.5067
85 T C 0.1951
86 Y C 0.8713
87 S C 0.0000
88 T C -0.1720
89 L C 0.0000
90 D C -0.2818
91 V C -0.2329
92 S C -0.4302
93 L C 0.0000
94 N C -1.5043
95 D C -2.3612
96 L C -2.3600
97 R C -2.6625
98 L C -1.5200
99 Q C -0.6009
100 I C -0.0683
101 S C -0.3294
102 F C 0.0000
103 F C 0.0000
104 E C -0.8449
105 Y C 0.0000
106 A C -0.6101
107 L C 0.0000
108 G C -1.2676
109 A C -1.3934
110 A C 0.0000
111 E C -3.6711
112 D C -3.5459
113 I C 0.0000
114 A C 0.0000
115 N C -3.2959
116 K C -3.6266
117 I C 0.0000
118 K C -3.0928
119 Q C -3.2705
120 T C -2.4709
121 T C 0.0000
122 D C -2.8579
123 E C -2.6283
124 Y C 0.0000
125 I C -0.5066
126 N C -0.8377
127 T C -0.3198
128 I C 0.5457
129 L C 0.6668
130 P C 0.0000
131 P C -0.7288
132 L C 0.0000
133 T C 0.0000
134 K C -0.1431
135 A C -0.6050
136 L C 0.0000
137 F C -0.6068
138 K C -1.5903
139 Y C -1.8246
140 V C 0.0000
141 R C -3.2591
142 E C -3.2245
143 G C -2.3735
144 K C -1.9868
145 Y C 0.4537
146 T C 0.9560
147 F C 2.1242
148 C C 1.2407
149 T C 0.3427
150 P C -0.1990
151 G C -0.0811
152 H C -0.3677
153 M C 0.4438
154 G C -0.7647
155 G C 0.0000
156 T C -0.7194
157 A C -0.7108
158 F C -0.2096
159 Q C -1.5058
160 K C -2.0342
161 S C -0.3797
162 P C 0.5086
163 V C 1.9382
164 G C 1.0770
165 S C 0.6977
166 L C 2.6285
167 F C 2.7195
168 Y C 1.2743
169 D C 0.4770
170 F C 2.4417
171 F C 1.7749
172 G C 0.2304
173 P C -0.9773
174 N C -1.7366
175 T C -0.5910
176 M C 0.0000
177 K C -1.5598
178 S C -1.1748
179 D C -0.9932
180 I C 0.0000
181 S C 0.0785
182 I C 0.5052
183 S C 0.3630
184 V C 0.0000
185 S C -0.7986
186 E C -1.7784
187 L C 0.0000
188 G C -1.4445
189 S C 0.0000
190 L C 0.0000
191 L C -0.9032
192 D C -2.0286
193 H C -1.9413
194 S C -2.0345
195 G C -2.0903
196 P C -2.0029
197 H C 0.0000
198 K C -3.3308
199 E C -3.1557
200 A C 0.0000
201 E C 0.0000
202 Q C -2.8046
203 Y C -1.9166
204 I C 0.0000
205 A C 0.0000
206 R C -2.6654
207 V C 0.0000
208 F C 0.0000
209 N C -1.9120
210 A C -1.7313
211 D C -1.9167
212 R C -1.5277
213 S C 0.0000
214 Y C 0.0000
215 M C 0.0000
216 V C 0.0000
217 T C 0.0000
218 N C -1.7155
219 G C -0.9802
220 T C 0.0000
221 S C -0.8726
222 T C 0.0000
223 A C 0.0000
224 N C 0.0000
225 K C 0.0370
226 I C 0.0000
227 V C 0.0000
228 G C 0.0000
229 M C 0.2441
230 Y C -0.1249
231 S C -0.0388
232 A C 0.0000
233 P C -0.4279
234 A C -0.7059
235 G C -1.0153
236 S C 0.0000
237 T C 0.0000
238 I C 0.0000
239 L C 0.0000
240 I C 0.0000
241 D C 0.0000
242 R C 0.0000
243 N C -0.5269
244 C C 0.0000
245 H C -1.4305
246 K C -1.7334
247 S C 0.0000
248 L C 0.0000
249 T C 0.0000
250 H C -0.3725
251 L C 0.0000
252 M C 0.0000
253 M C 0.4828
254 M C 0.6511
255 S C 0.0000
256 D C -0.9730
257 V C 0.0000
258 T C 0.0000
259 P C 0.0000
260 I C 0.0000
261 Y C 0.0000
262 F C 0.0000
263 R C -0.6484
264 P C 0.0000
265 T C -0.4303
266 R C 0.0000
267 N C 0.0000
268 A C -1.1541
269 Y C -0.0996
270 G C -0.1883
271 I C 0.0000
272 L C 0.0000
273 G C 0.0000
274 G C 0.0000
275 I C 0.0000
276 P C -0.7568
277 Q C -0.6815
278 S C -0.7906
279 E C 0.0000
280 F C 0.0000
281 Q C -1.5215
282 H C -1.5701
283 A C -1.0020
284 T C -1.0816
285 I C 0.0000
286 A C -1.7261
287 K C -2.8674
288 R C -2.3268
289 V C -2.0500
290 K C -3.3600
291 E C -3.3401
292 T C -1.9827
293 P C -1.4785
294 N C -1.8883
295 A C -1.3278
296 T C -0.5013
297 W C 0.0029
298 P C 0.0000
299 V C -0.2963
300 H C 0.0000
301 A C 0.0000
302 V C 0.0000
303 I C 0.0000
304 T C 0.0000
305 N C 0.0000
306 S C 0.0000
307 T C 0.0000
308 Y C 0.2440
309 D C 0.0000
310 G C 0.0000
311 L C 0.0000
312 L C 0.0000
313 Y C 0.0000
314 N C -1.4171
315 T C 0.0000
316 D C -2.4513
317 F C -1.3993
318 I C 0.0000
319 K C 0.0000
320 K C -2.4006
321 T C -1.6762
322 L C 0.0000
323 D C -2.1346
324 V C 0.0000
325 K C -2.2994
326 S C 0.0000
327 I C 0.0000
328 H C 0.0000
329 F C 0.0000
330 D C 0.0000
331 S C 0.0000
332 A C -0.0163
333 W C 0.2616
334 V C 0.0000
335 P C 0.0000
336 Y C 0.0000
337 T C 0.0000
338 N C -1.2229
339 F C 0.0000
340 S C 0.0000
341 P C -1.2377
342 I C -0.8779
343 Y C 0.0000
344 E C -2.3579
345 G C -1.7428
346 K C -1.2987
347 C C 0.0000
348 G C 0.0000
349 M C 0.0000
350 S C -1.7789
351 G C -1.8532
352 G C -1.9132
353 R C -2.8830
354 V C -2.5454
355 E C -3.0747
356 G C -2.4439
357 K C -2.4184
358 V C 0.0000
359 I C 0.0000
360 Y C 0.0000
361 E C 0.0000
362 T C 0.0000
363 Q C 0.0000
364 S C -0.2690
365 T C 0.0000
366 H C -0.1618
368 L C 0.1265
369 L C 0.0000
370 A C 0.3074
371 A C 0.6097