| Chain sequence(s) |
A: IEQPRWASKDSAAGAASTPDEKIVLEFMDALTSNDAAKLIEYFAEDTMYQNMPLPPAYGRDAVEQTLAGLFTVMMSIDAVETFHIGSSNGLLVYTERVDVLLRALPTGKSYNLSILGVFQLTEGKITGWRDYFDLREFEEAVDLPLRG B: KIEQPRWASKDSAAGAASTPDEKIVLEFMDALTSNDAAKLIEYFAEDTMYQNMPLPPAYGRDAVEQTLAGLLFTVMMSIDAVETFHIGSSNGLVYTERVDVLLRALPTGKSYNLSILGVFQLTEGKITGWRDYFDLREFEEAVDLPLRG |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 5 | I | A | -0.1242 | |
| 6 | E | A | -1.9762 | |
| 7 | Q | A | -2.0884 | |
| 8 | P | A | -1.6551 | |
| 9 | R | A | -2.2964 | |
| 10 | W | A | -1.1005 | |
| 11 | A | A | 0.0000 | |
| 12 | S | A | -2.0855 | |
| 13 | K | A | -2.9508 | |
| 14 | D | A | -2.8863 | |
| 15 | S | A | -1.5371 | |
| 16 | A | A | -1.1506 | |
| 17 | A | A | -1.4308 | |
| 18 | G | A | -0.8873 | |
| 19 | A | A | -0.4748 | |
| 20 | A | A | -0.8450 | |
| 21 | S | A | -0.8016 | |
| 22 | T | A | -0.7831 | |
| 23 | P | A | -1.0545 | |
| 24 | D | A | -1.7419 | |
| 25 | E | A | 0.0000 | |
| 26 | K | A | -2.0207 | |
| 27 | I | A | -1.4604 | |
| 28 | V | A | 0.0000 | |
| 29 | L | A | -1.6610 | |
| 30 | E | A | -2.5871 | |
| 31 | F | A | 0.0000 | |
| 32 | M | A | 0.0000 | |
| 33 | D | A | -2.4425 | |
| 34 | A | A | 0.0000 | |
| 35 | L | A | 0.0000 | |
| 36 | T | A | -1.0483 | |
| 37 | S | A | -1.2684 | |
| 38 | N | A | -1.1895 | |
| 39 | D | A | -1.6254 | |
| 40 | A | A | -1.5793 | |
| 41 | A | A | -1.5428 | |
| 42 | K | A | -2.0959 | |
| 43 | L | A | 0.0000 | |
| 44 | I | A | 0.0000 | |
| 45 | E | A | -2.5049 | |
| 46 | Y | A | -1.3590 | |
| 47 | F | A | 0.0000 | |
| 48 | A | A | -2.4051 | |
| 49 | E | A | -3.4162 | |
| 50 | D | A | -2.9991 | |
| 51 | T | A | 0.0000 | |
| 52 | M | A | 0.0000 | |
| 53 | Y | A | 0.0000 | |
| 54 | Q | A | -0.1463 | |
| 55 | N | A | -0.1761 | |
| 56 | M | A | 0.0199 | |
| 57 | P | A | 0.0000 | |
| 58 | L | A | -0.1463 | |
| 59 | P | A | -0.2453 | |
| 60 | P | A | -0.1031 | |
| 61 | A | A | -0.4632 | |
| 62 | Y | A | -0.6951 | |
| 63 | G | A | -1.8099 | |
| 64 | R | A | -2.8847 | |
| 65 | D | A | -3.0114 | |
| 66 | A | A | -1.5552 | |
| 67 | V | A | 0.0000 | |
| 68 | E | A | -2.5414 | |
| 69 | Q | A | -2.1326 | |
| 70 | T | A | -1.1840 | |
| 71 | L | A | 0.0000 | |
| 72 | A | A | -0.8205 | |
| 73 | G | A | -0.4462 | |
| 74 | L | A | -0.0889 | |
| 75 | F | A | 0.1210 | |
| 76 | T | A | 0.2915 | |
| 77 | V | A | 0.6352 | |
| 78 | M | A | 0.0000 | |
| 79 | S | A | 0.0000 | |
| 80 | I | A | 0.0000 | |
| 81 | D | A | -1.2750 | |
| 82 | A | A | -0.8522 | |
| 83 | V | A | -0.7939 | |
| 84 | E | A | -1.4297 | |
| 85 | T | A | -0.7719 | |
| 86 | F | A | 0.0000 | |
| 87 | H | A | 0.0000 | |
| 88 | I | A | 0.0000 | |
| 89 | G | A | 0.0000 | |
| 90 | S | A | -0.4817 | |
| 91 | S | A | -0.4020 | |
| 92 | N | A | -0.9593 | |
| 93 | G | A | -1.1383 | |
| 94 | L | A | 0.0000 | |
| 95 | V | A | 0.0000 | |
| 96 | Y | A | 0.0000 | |
| 97 | T | A | 0.0000 | |
| 98 | E | A | 0.0000 | |
| 99 | R | A | 0.0000 | |
| 100 | V | A | 0.0000 | |
| 101 | D | A | 0.0000 | |
| 102 | V | A | -0.6268 | |
| 103 | L | A | 0.0000 | |
| 104 | R | A | -1.4191 | |
| 105 | A | A | 0.0000 | |
| 106 | L | A | 0.2768 | |
| 107 | P | A | -0.4185 | |
| 108 | T | A | -1.0493 | |
| 109 | G | A | -1.4266 | |
| 110 | K | A | -2.1703 | |
| 111 | S | A | -1.6410 | |
| 112 | Y | A | -1.2219 | |
| 113 | N | A | -1.1936 | |
| 114 | L | A | 0.0000 | |
| 115 | S | A | -0.4417 | |
| 116 | I | A | 0.0000 | |
| 117 | L | A | 0.0000 | |
| 118 | G | A | 0.0000 | |
| 119 | V | A | 0.0000 | |
| 120 | F | A | 0.0000 | |
| 121 | Q | A | -0.4561 | |
| 122 | L | A | -0.9695 | |
| 123 | T | A | -1.4242 | |
| 124 | E | A | -2.3181 | |
| 125 | G | A | -1.7644 | |
| 126 | K | A | -2.2760 | |
| 127 | I | A | 0.0000 | |
| 128 | T | A | -1.2566 | |
| 129 | G | A | 0.0000 | |
| 130 | W | A | 0.0000 | |
| 131 | R | A | 0.0000 | |
| 132 | D | A | 0.0000 | |
| 133 | Y | A | 0.0000 | |
| 134 | F | A | 0.0000 | |
| 135 | D | A | 0.0000 | |
| 136 | L | A | 0.0000 | |
| 137 | R | A | -1.4500 | |
| 138 | E | A | -1.6127 | |
| 139 | F | A | 0.0000 | |
| 140 | E | A | 0.0000 | |
| 141 | E | A | -2.7111 | |
| 142 | A | A | -2.0264 | |
| 143 | V | A | 0.0000 | |
| 144 | D | A | -2.6741 | |
| 145 | L | A | -1.4025 | |
| 146 | P | A | -1.2363 | |
| 147 | L | A | -0.8989 | |
| 148 | R | A | -1.1963 | |
| 149 | G | A | -0.9427 | |
| 4 | K | B | -2.2263 | |
| 5 | I | B | -1.9670 | |
| 6 | E | B | -3.1210 | |
| 7 | Q | B | -2.7368 | |
| 8 | P | B | -1.8899 | |
| 9 | R | B | -2.2474 | |
| 10 | W | B | -1.1324 | |
| 11 | A | B | -1.3106 | |
| 12 | S | B | -1.5414 | |
| 13 | K | B | -2.2696 | |
| 14 | D | B | -1.9345 | |
| 15 | S | B | -1.1713 | |
| 16 | A | B | -0.8358 | |
| 17 | A | B | 0.0000 | |
| 18 | G | B | -0.9230 | |
| 19 | A | B | -0.5147 | |
| 20 | A | B | -0.9816 | |
| 21 | S | B | -0.7947 | |
| 22 | T | B | -0.8879 | |
| 23 | P | B | -1.2252 | |
| 24 | D | B | -2.1159 | |
| 25 | E | B | 0.0000 | |
| 26 | K | B | -2.1798 | |
| 27 | I | B | -1.5871 | |
| 28 | V | B | 0.0000 | |
| 29 | L | B | -1.6724 | |
| 30 | E | B | -2.6079 | |
| 31 | F | B | 0.0000 | |
| 32 | M | B | 0.0000 | |
| 33 | D | B | -2.4462 | |
| 34 | A | B | 0.0000 | |
| 35 | L | B | 0.0000 | |
| 36 | T | B | -1.0109 | |
| 37 | S | B | -1.2476 | |
| 38 | N | B | -1.2053 | |
| 39 | D | B | -1.6833 | |
| 40 | A | B | -1.6132 | |
| 41 | A | B | -1.5654 | |
| 42 | K | B | -2.1588 | |
| 43 | L | B | 0.0000 | |
| 44 | I | B | 0.0000 | |
| 45 | E | B | -2.5241 | |
| 46 | Y | B | -1.5011 | |
| 47 | F | B | 0.0000 | |
| 48 | A | B | -2.4119 | |
| 49 | E | B | -3.4004 | |
| 50 | D | B | -3.0266 | |
| 51 | T | B | 0.0000 | |
| 52 | M | B | 0.0000 | |
| 53 | Y | B | 0.0000 | |
| 54 | Q | B | -0.1467 | |
| 55 | N | B | -0.1419 | |
| 56 | M | B | 0.0332 | |
| 57 | P | B | 0.0000 | |
| 58 | L | B | -0.1824 | |
| 59 | P | B | -0.2725 | |
| 60 | P | B | -0.1289 | |
| 61 | A | B | 0.0000 | |
| 62 | Y | B | -0.6889 | |
| 63 | G | B | -1.7991 | |
| 64 | R | B | -2.8944 | |
| 65 | D | B | -3.0288 | |
| 66 | A | B | -1.5694 | |
| 67 | V | B | 0.0000 | |
| 68 | E | B | -2.5793 | |
| 69 | Q | B | -2.1639 | |
| 70 | T | B | -1.2096 | |
| 71 | L | B | 0.0000 | |
| 72 | A | B | -0.8474 | |
| 73 | G | B | -0.4871 | |
| 74 | L | B | -0.1203 | |
| 75 | F | B | 0.1220 | |
| 76 | T | B | 0.2170 | |
| 77 | V | B | 0.7239 | |
| 78 | M | B | 0.0000 | |
| 79 | S | B | -0.3922 | |
| 80 | I | B | 0.0000 | |
| 81 | D | B | -0.9921 | |
| 82 | A | B | -1.1113 | |
| 83 | V | B | -0.8255 | |
| 84 | E | B | -1.6736 | |
| 85 | T | B | -0.6779 | |
| 86 | F | B | -0.4082 | |
| 87 | H | B | 0.0000 | |
| 88 | I | B | 0.0000 | |
| 89 | G | B | 0.0000 | |
| 90 | S | B | -0.6809 | |
| 91 | S | B | -0.8585 | |
| 92 | N | B | -1.8330 | |
| 93 | G | B | -1.3649 | |
| 94 | L | B | 0.0000 | |
| 95 | V | B | 0.0000 | |
| 96 | Y | B | 0.0000 | |
| 97 | T | B | 0.0000 | |
| 98 | E | B | 0.0000 | |
| 99 | R | B | 0.0000 | |
| 100 | V | B | -0.5966 | |
| 101 | D | B | 0.0000 | |
| 102 | V | B | 0.0000 | |
| 103 | L | B | 0.0000 | |
| 104 | R | B | -1.2056 | |
| 105 | A | B | 0.0000 | |
| 106 | L | B | 0.5844 | |
| 107 | P | B | -0.2797 | |
| 108 | T | B | -0.9418 | |
| 109 | G | B | -1.3154 | |
| 110 | K | B | -2.0419 | |
| 111 | S | B | -1.4185 | |
| 112 | Y | B | -0.9821 | |
| 113 | N | B | -1.0431 | |
| 114 | L | B | 0.0000 | |
| 115 | S | B | -0.2268 | |
| 116 | I | B | 0.0000 | |
| 117 | L | B | 0.0000 | |
| 118 | G | B | 0.0000 | |
| 119 | V | B | 0.0000 | |
| 120 | F | B | 0.0000 | |
| 121 | Q | B | -0.9863 | |
| 122 | L | B | -1.1998 | |
| 123 | T | B | -1.5502 | |
| 124 | E | B | -2.3157 | |
| 125 | G | B | -1.8809 | |
| 126 | K | B | -2.3774 | |
| 127 | I | B | 0.0000 | |
| 128 | T | B | -1.3439 | |
| 129 | G | B | 0.0000 | |
| 130 | W | B | 0.0000 | |
| 131 | R | B | 0.0000 | |
| 132 | D | B | 0.0000 | |
| 133 | Y | B | 0.0000 | |
| 134 | F | B | 0.0000 | |
| 135 | D | B | 0.0000 | |
| 136 | L | B | 0.0000 | |
| 137 | R | B | -1.4392 | |
| 138 | E | B | -1.5573 | |
| 139 | F | B | 0.0000 | |
| 140 | E | B | 0.0000 | |
| 141 | E | B | -2.6956 | |
| 142 | A | B | -1.9303 | |
| 143 | V | B | 0.0000 | |
| 144 | D | B | -2.6731 | |
| 145 | L | B | -1.3702 | |
| 146 | P | B | -1.2914 | |
| 147 | L | B | -0.9427 | |
| 148 | R | B | -1.3743 | |
| 149 | G | B | -1.0261 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine