Project name: 66912f0243827f6

Chain sequence(s)	A: ETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGAGKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSQSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKV
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6146
• Maximal score value: 2.5521
• Average score: -0.7857
• Total score value: -186.9854

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	E	A	-2.2898
3	T	A	-2.0566
4	N	A	-2.6779
5	N	A	-2.8223
6	E	A	-2.4250
7	C	A	-0.4096
8	S	A	0.5547
9	I	A	1.6032
10	K	A	0.0879
11	V	A	1.3197
12	L	A	0.2314
13	C	A	0.4558
14	R	A	-0.3306
15	F	A	-0.3494
16	R	A	-1.0619
17	P	A	-0.6257
18	L	A	-0.0739
19	N	A	-0.9008
20	Q	A	-0.8107
21	A	A	-0.3342
22	E	A	-0.4829
23	I	A	0.9960
24	L	A	0.9151
25	R	A	-1.3733
26	G	A	-0.8416
27	D	A	-0.9985
28	K	A	-1.1320
29	F	A	1.0932
30	I	A	2.1823
31	P	A	1.8454
32	I	A	2.1238
33	F	A	0.4900
34	Q	A	-1.1506
35	G	A	-1.8648
36	D	A	-2.6636
37	D	A	-1.6940
38	S	A	-0.2654
39	V	A	0.0000
40	V	A	0.8791
41	I	A	1.1496
42	G	A	0.2467
43	A	A	-0.5269
44	G	A	-0.9530
45	K	A	-1.5068
46	P	A	-0.1786
47	Y	A	0.9218
48	V	A	1.2086
49	F	A	0.3579
50	D	A	-1.3451
51	R	A	-1.4263
52	V	A	0.0000
53	F	A	0.0000
54	P	A	-0.6351
55	P	A	-0.9269
56	N	A	-1.5252
57	T	A	-1.1575
58	T	A	-0.9719
59	Q	A	0.0000
60	E	A	-1.4102
61	Q	A	-1.7272
62	V	A	0.0000
63	Y	A	0.0000
64	H	A	-1.5604
65	A	A	-1.1596
66	C	A	-0.6464
67	A	A	0.0000
68	M	A	-1.0596
69	Q	A	-1.4894
70	I	A	-0.6567
71	V	A	0.0000
72	K	A	-1.3822
73	D	A	-0.8920
74	V	A	0.0000
75	L	A	0.0000
76	A	A	-0.1079
77	G	A	-0.3418
78	Y	A	0.3640
79	N	A	-0.8672
80	G	A	-0.5905
81	T	A	0.6862
82	I	A	1.6163
83	F	A	2.5521
84	A	A	1.5917
85	Y	A	1.5023
86	G	A	-0.3890
87	Q	A	-1.7637
88	T	A	-1.3941
89	S	A	-0.9485
90	S	A	-0.8359
91	G	A	-0.8654
92	K	A	-0.4057
93	T	A	-0.8547
94	H	A	-1.5322
95	T	A	-0.7564
96	M	A	0.0000
97	E	A	-1.0636
98	G	A	-1.5681
99	K	A	-2.1807
100	L	A	-1.5389
101	H	A	-1.9735
102	D	A	-1.6612
103	P	A	-1.4167
104	Q	A	-1.6272
105	L	A	-1.1460
106	M	A	-1.4028
107	G	A	0.0000
108	I	A	0.0000
109	I	A	0.0000
110	P	A	0.0000
111	R	A	-1.1753
112	I	A	0.0000
113	A	A	0.0000
114	R	A	-2.6837
115	D	A	-1.6690
116	I	A	0.0000
117	F	A	0.0000
118	N	A	-1.4440
119	H	A	-0.7639
120	I	A	-0.1858
121	Y	A	0.4430
122	S	A	-0.3468
123	M	A	-0.9000
124	D	A	-2.6830
125	E	A	-3.0088
126	N	A	-2.8166
127	L	A	-2.9227
128	E	A	-2.8805
129	F	A	-1.6163
130	H	A	-1.3508
131	I	A	0.0000
132	K	A	-0.6529
133	V	A	0.0000
134	S	A	0.0000
135	Y	A	0.0000
136	F	A	0.0000
137	E	A	0.0000
138	I	A	-0.5011
139	Y	A	-0.3349
140	L	A	0.2092
141	D	A	-1.8356
142	K	A	-2.3035
143	I	A	0.0000
144	R	A	-1.2881
145	D	A	0.0000
146	L	A	0.0000
147	L	A	0.0000
148	D	A	-1.1111
149	V	A	-0.4988
150	T	A	-0.6324
151	K	A	-1.4124
152	T	A	-1.4827
153	N	A	-2.0671
154	L	A	-1.0959
155	S	A	-0.3606
156	V	A	0.5470
157	H	A	-1.4232
158	E	A	-3.3150
159	D	A	-3.4128
160	K	A	-3.5943
161	N	A	-3.3355
162	R	A	-3.6146
163	V	A	-1.6013
164	P	A	-1.3606
165	F	A	-0.4424
166	V	A	-0.2181
167	K	A	-1.3327
168	G	A	-1.1659
169	C	A	-1.1837
170	T	A	-1.5393
171	E	A	-1.7645
172	R	A	-0.7220
173	F	A	0.6804
174	V	A	0.0000
175	S	A	-0.5265
176	S	A	-1.3274
177	P	A	0.0000
178	E	A	-3.2214
179	E	A	-2.3779
180	I	A	0.0000
181	L	A	0.0000
182	D	A	-3.0685
183	V	A	0.0000
184	I	A	0.0000
185	D	A	-2.0475
186	E	A	-1.8938
187	G	A	0.0000
188	K	A	-1.9261
189	S	A	-1.2042
190	N	A	-0.7910
191	R	A	0.0000
192	H	A	-0.5816
193	V	A	0.9933
194	A	A	0.5876
195	V	A	-0.1656
196	T	A	-0.6380
197	N	A	-1.8632
198	M	A	-1.5899
199	N	A	-2.4991
200	E	A	-2.9261
201	H	A	0.0000
202	S	A	-1.5669
203	S	A	-1.7241
204	Q	A	-1.2895
205	S	A	0.0000
206	H	A	-0.0497
207	S	A	-0.0240
208	I	A	0.0000
209	F	A	0.0000
210	L	A	0.0000
211	I	A	0.0000
212	N	A	0.0000
213	I	A	0.0000
214	K	A	-1.9831
215	Q	A	0.0000
216	E	A	-3.4843
217	N	A	-3.2075
218	M	A	-2.1885
219	E	A	-2.6564
220	T	A	-2.4443
221	E	A	-3.4358
222	Q	A	-3.3152
223	K	A	-3.2981
224	L	A	-1.1071
225	S	A	-0.9857
226	G	A	0.0000
227	K	A	-0.8608
228	L	A	0.0000
229	Y	A	0.3153
230	L	A	0.0000
231	V	A	1.1391
232	D	A	0.5796
233	L	A	0.5597
234	A	A	-0.4851
235	G	A	-1.2347
236	S	A	-1.0994
237	E	A	-2.0117
238	K	A	-1.5418
239	V	A	0.6811