Project name: 2WCV [mutate: EA77L, EB77L, EC77L, ED77L, EE77L, EF77L, EG77L, EH77L, EI77L, EJ77L]

Status: done

submitted: 2017-09-13 11:04:43, status changed: 2017-09-13 11:28:35
Settings
Chain sequence(s) A: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
C: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
B: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
E: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
D: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
G: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
F: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
I: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
H: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
J: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
Distance of aggregation 10 Å
Dynamic mode No
Mutated residues EA77L, EB77L, EC77L, ED77L, EE77L, EF77L, EG77L, EH77L, EI77L, EJ77L
Energy difference between WD and mutated (by FoldX) -2.45987 kcal/mol
Show buried residues

Minimal score value
-3.7155
Maximal score value
1.4699
Average score
-0.4929
Total score value
-687.6054

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
1 M A 1.4699
2 L A 1.2603
3 K A -0.6434
4 T A -0.2068
5 I A 0.6701
6 S A 0.3480
7 P A 0.5483
8 L A 0.5338
9 I A 0.0000
10 S A -0.7339
11 P A -1.1126
12 E A -2.4394
13 L A 0.0000
14 L A -1.1468
15 K A -2.4379
16 V A 0.0000
17 L A 0.0000
18 A A -0.8463
19 E A -1.1282
20 M A 0.0000
21 G A 0.0000
22 H A 0.0000
23 G A -0.1053
24 D A 0.0000
25 E A -0.5856
26 I A 0.0000
27 I A 0.0000
28 F A 0.0000
29 S A 0.0000
30 D A 0.0000
31 A A -1.1215
32 H A -0.5904
33 F A 0.0000
34 P A 0.0000
35 A A 0.0000
36 H A -0.5908
37 S A -0.6833
38 M A -1.3017
39 G A -1.3265
40 P A -1.2596
41 Q A -0.9210
42 V A -0.3521
43 I A -0.8164
44 R A -1.2682
45 A A -1.0882
46 D A -2.1028
47 G A -1.4398
48 L A -0.6711
49 L A -0.4332
50 V A 0.0000
51 S A 0.0000
52 D A -0.7999
53 L A 0.0000
54 L A 0.0000
55 Q A -1.5741
56 A A 0.0000
57 I A 0.0000
58 I A -0.0982
59 P A -0.0745
60 L A 0.5163
61 F A 0.0000
62 E A -0.6156
63 L A -0.1540
64 D A 0.0000
65 S A -0.2266
66 Y A 0.0840
67 A A -0.2438
68 P A -0.3946
69 P A 0.0000
70 L A 0.0000
71 V A 0.0000
72 M A 0.0000
73 M A 0.0000
74 A A 0.1733
75 A A -0.2509
76 V A 0.0000
77 L A 0.0169 mutated: EA77L
78 G A -0.2522
79 D A -0.2335
80 T A -0.5182
81 L A -0.9937
82 D A -2.4725
83 P A -2.3103
84 E A -3.2420
85 V A 0.0000
86 E A -2.5409
87 R A -3.4242
88 R A -2.6470
89 Y A 0.0000
90 R A -2.8712
91 N A -2.5127
92 A A -1.8544
93 L A 0.0000
94 S A -0.9725
95 L A -0.6486
98 P A -0.0552
99 C A 0.0933
100 P A -0.3763
101 D A -1.4849
102 I A 0.0000
103 I A 0.4423
104 R A -0.0512
105 I A 0.2956
106 N A -0.1465
107 R A 0.0000
108 F A 0.4885
109 A A -0.2784
110 F A 0.0000
111 Y A -0.9576
112 E A -2.3592
113 R A -1.9742
114 A A 0.0000
115 Q A -2.6319
116 K A -2.7483
117 A A 0.0000
118 F A -0.7801
119 A A 0.0000
120 I A 0.0000
121 V A 0.0000
122 I A 0.0000
123 T A 0.0000
124 G A -1.3940
125 E A 0.0000
126 R A -2.0230
127 A A -1.6650
128 K A -1.4005
129 Y A 0.0000
130 G A 0.0000
131 N A 0.0000
132 I A 0.0000
133 L A 0.0000
134 L A 0.0000
135 K A -0.3888
136 K A 0.0000
137 G A 0.0000
138 V A -0.3310
139 T A -0.3938
140 P A -0.6023
1 M B 1.1962
2 L B 0.7121
3 K B -0.9363
4 T B -0.3911
5 I B 0.3749
6 S B 0.1490
7 P B 0.4139
8 L B 0.4679
9 I B 0.0000
10 S B -0.7025
11 P B -1.1022
12 E B -2.3082
13 L B 0.0000
14 L B -1.1334
15 K B -2.3595
16 V B 0.0000
17 L B 0.0000
18 A B -0.6343
19 E B -1.1261
20 M B 0.0000
21 G B 0.0000
22 H B -0.2230
23 G B 0.0473
24 D B 0.0000
25 E B -0.6276
26 I B 0.0000
27 I B 0.0000
28 F B 0.0000
29 S B 0.0000
30 D B 0.0000
31 A B -1.1369
32 H B 0.0000
33 F B 0.0000
34 P B 0.0000
35 A B 0.0000
36 H B -0.6496
37 S B -0.7770
38 M B -0.9071
39 G B -1.2981
40 P B -1.2681
41 Q B -1.0127
42 V B -0.4000
43 I B -0.8385
44 R B -1.2937
45 A B -1.0696
46 D B -2.0651
47 G B -1.3639
48 L B -0.3429
49 L B -0.2622
50 V B 0.0000
51 S B -1.1783
52 D B -0.7518
53 L B 0.0000
54 L B 0.0000
55 Q B -1.6631
56 A B 0.0000
57 I B 0.0000
58 I B 0.0000
59 P B -0.3344
60 L B 0.2938
61 F B 0.0000
62 E B -0.7427
63 L B -0.2374
64 D B 0.0000
65 S B -0.0802
66 Y B 0.2873
67 A B 0.1648
68 P B -0.3498
69 P B 0.0000
70 L B 0.0000
71 V B 0.0000
72 M B 0.0000
73 M B 0.0000
74 A B 0.0000
75 A B -0.1311
76 V B 0.5462
77 L B 0.8303 mutated: EB77L
78 G B 0.3626
79 D B 0.1288
80 T B -0.0230
81 L B -0.6585
82 D B -2.1036
83 P B -2.0293
84 E B -2.7283
85 V B 0.0000
86 E B -2.5307
87 R B -3.6572
88 R B -2.7930
89 Y B 0.0000
90 R B -3.1742
91 N B -2.7115
92 A B 0.0000
93 L B 0.0000
94 S B -1.1181
95 L B -0.5062
96 Q B -1.1063
97 A B -0.5519
98 P B -0.9230
99 C B -0.9962
100 P B -1.1384
101 D B -1.9933
102 I B 0.0000
103 I B -0.6722
104 R B -0.5157
105 I B 0.0000
106 N B -0.3750
107 R B -0.0840
108 F B 0.4255
109 A B 0.0000
110 F B 0.0000
111 Y B -0.2193
112 E B 0.0000
113 R B -0.8489
114 A B 0.0000
115 Q B -1.8040
116 K B -2.0991
117 A B 0.0000
118 F B 0.0000
119 A B 0.0000
120 I B 0.0000
121 V B 0.0000
122 I B 0.0000
123 T B 0.0000
124 G B -1.2823
125 E B 0.0000
126 R B -2.0708
127 A B -1.5257
128 K B -1.5849
129 Y B 0.0000
130 G B 0.0000
131 N B 0.0000
132 I B 0.0000
133 L B 0.0000
134 L B 0.0000
135 K B -0.4096
136 K B 0.0000
137 G B 0.0000
138 V B -0.2991
139 T B -0.4317
140 P B -0.5364
1 M C 1.4046
2 L C 1.0868
3 K C -0.7245
4 T C -0.2406
5 I C 0.6158
6 S C 0.4120
7 P C 0.6114
8 L C 0.6866
9 I C 0.0000
10 S C -0.6843
11 P C -1.1100
12 E C -2.3799
13 L C 0.0000
14 L C -1.1533
15 K C -2.4092
16 V C 0.0000
17 L C 0.0000
18 A C -0.8184
19 E C -1.0587
20 M C 0.0000
21 G C 0.0000
22 H C 0.0000
23 G C -0.1574
24 D C 0.0000
25 E C -0.7007
26 I C 0.0000
27 I C 0.0000
28 F C 0.0000
29 S C 0.0000
30 D C 0.0000
31 A C -1.0794
32 H C -0.6030
33 F C 0.0000
34 P C 0.0000
35 A C 0.0000
36 H C -0.5874
37 S C -0.9258
38 M C 0.0000
39 G C -1.4455
40 P C -1.2638
41 Q C -0.7937
42 V C -0.2608
43 I C -0.7384
44 R C -1.2125
45 A C -1.0335
46 D C -2.0532
47 G C -1.1897
48 L C -0.6081
49 L C -0.3722
50 V C 0.0000
51 S C -0.8146
52 D C -0.6794
53 L C 0.0000
54 L C 0.0000
55 Q C -1.3287
56 A C -0.3112
57 I C 0.0000
58 I C -0.1367
59 P C -0.1214
60 L C 0.4077
61 F C 0.0000
62 E C -0.8124
63 L C -0.3193
64 D C 0.0000
65 S C -0.1594
66 Y C 0.4602
67 A C 0.0054
68 P C -0.3898
69 P C 0.0000
70 L C 0.0000
71 V C 0.0000
72 M C 0.0000
73 M C 0.0000
74 A C -0.2173
75 A C -0.1489
76 V C 0.3814
77 L C 0.9753 mutated: EC77L
78 G C 0.0239
79 D C 0.0130
80 T C -0.2244
81 L C -0.6882
82 D C -2.0489
83 P C -2.1312
84 E C -3.0269
85 V C 0.0000
86 E C -2.3579
87 R C -3.4395
88 R C -2.5553
89 Y C 0.0000
90 R C -2.3554
91 N C -2.3865
92 A C 0.0000
93 L C 0.0000
94 S C -0.8986
97 A C -0.0999
98 P C -0.6828
99 C C -0.8388
100 P C -1.0092
101 D C -1.7402
102 I C 0.0000
103 I C 0.2032
104 R C -0.2821
105 I C -0.4933
106 N C -1.3514
107 R C -0.9804
108 F C 0.0000
109 A C -1.1076
110 F C 0.0000
111 Y C 0.0000
112 E C -1.8419
113 R C -2.1617
114 A C 0.0000
115 Q C -2.6754
116 K C -2.8191
117 A C 0.0000
118 F C -0.8649
119 A C 0.0000
120 I C 0.0000
121 V C 0.0000
122 I C 0.0000
123 T C 0.0000
124 G C 0.0000
125 E C 0.0000
126 R C -1.8977
127 A C -1.5320
128 K C -1.2176
129 Y C -0.6301
130 G C 0.0000
131 N C 0.0000
132 I C 0.0000
133 L C 0.0000
134 L C 0.0000
135 K C -0.4912
136 K C 0.0000
137 G C 0.0000
138 V C -0.4045
139 T C -0.5785
140 P C -0.7530
1 M D 1.3770
2 L D 1.1057
3 K D -0.7081
4 T D -0.2075
5 I D 0.6569
6 S D 0.2056
7 P D 0.4179
8 L D 0.2789
9 I D 0.0000
10 S D -0.7287
11 P D -1.1275
12 E D -2.4165
13 L D 0.0000
14 L D -1.2008
15 K D -2.4209
16 V D 0.0000
17 L D 0.0000
18 A D -0.8341
19 E D -1.1481
20 M D 0.0000
21 G D 0.0000
22 H D 0.0000
23 G D -0.1908
24 D D 0.0000
25 E D -0.6348
26 I D 0.0000
27 I D 0.0000
28 F D 0.0000
29 S D 0.0000
30 D D 0.0000
31 A D -1.0573
32 H D 0.0000
33 F D 0.0000
34 P D 0.0000
35 A D 0.0000
36 H D -0.5933
37 S D -0.7887
38 M D -1.0454
39 G D -1.3194
40 P D -1.2534
41 Q D -0.8997
42 V D -0.4700
43 I D -0.7421
44 R D -1.2965
45 A D -0.9499
46 D D -1.9606
47 G D -1.2856
48 L D -0.5131
49 L D -0.1654
50 V D 0.0000
51 S D 0.0000
52 D D -1.2457
53 L D 0.0000
54 L D 0.0000
55 Q D -1.5569
56 A D -0.4546
57 I D 0.0000
58 I D -0.1251
59 P D -0.1402
60 L D 0.4716
61 F D 0.0000
62 E D -0.5172
63 L D -0.0794
64 D D 0.0000
65 S D -0.0544
66 Y D 0.2515
67 A D -0.0266
68 P D -0.3049
69 P D 0.0000
70 L D 0.0000
71 V D 0.0000
72 M D 0.0000
73 M D 0.0000
74 A D -0.1986
75 A D -0.2875
76 V D 0.5575
77 L D 1.3227 mutated: ED77L
78 G D 0.1511
79 D D -0.4636
80 T D -0.5440
81 L D -1.1495
82 D D -2.5724
83 P D -2.4209
84 E D -3.2418
85 V D 0.0000
86 E D -2.4669
87 R D -3.5994
88 R D -2.8202
89 Y D 0.0000
90 R D -2.3433
91 N D -2.2327
92 A D 0.0000
93 L D 0.0000
94 S D -0.8975
95 L D -0.3367
96 Q D -0.9178
97 A D -0.5384
98 P D -0.8339
99 C D -0.8422
100 P D -1.0356
101 D D -1.8033
102 I D 0.0000
103 I D -0.0076
104 R D -0.4047
105 I D -0.4360
106 N D -1.1702
107 R D -0.6221
108 F D -0.1383
109 A D -0.4794
110 F D 0.0000
111 Y D -0.6599
112 E D -1.1766
113 R D -1.3281
114 A D 0.0000
115 Q D -2.1380
116 K D -2.4732
117 A D 0.0000
118 F D 0.0000
119 A D 0.0000
120 I D 0.0000
121 V D 0.0000
122 I D 0.0000
123 T D 0.0000
124 G D 0.0000
125 E D 0.0000
126 R D -1.9738
127 A D -1.6556
128 K D -1.5824
129 Y D 0.0000
130 G D 0.0000
131 N D 0.0000
132 I D 0.0000
133 L D 0.0000
134 L D 0.0000
135 K D -0.3383
136 K D 0.0000
137 G D 0.0000
138 V D -0.2627
139 T D -0.4116
140 P D -0.5813
1 M E 1.3809
2 L E 1.0510
3 K E -0.7541
4 T E -0.2781
5 I E 0.5723
6 S E 0.1781
7 P E 0.5387
8 L E 0.5633
9 I E 0.0000
10 S E -0.6889
11 P E -1.1169
12 E E -2.4389
13 L E 0.0000
14 L E -1.2305
15 K E -2.4405
16 V E 0.0000
17 L E 0.0000
18 A E -0.8393
19 E E -1.1678
20 M E 0.0000
21 G E 0.0000
22 H E 0.0000
23 G E -0.0983
24 D E 0.0000
25 E E -0.5441
26 I E 0.0000
27 I E 0.0000
28 F E 0.0000
29 S E 0.0000
30 D E 0.0000
31 A E -1.0632
32 H E -0.6182
33 F E 0.0000
34 P E 0.0000
35 A E 0.0000
36 H E -0.5843
37 S E -0.7949
38 M E 0.0000
39 G E -1.1643
40 P E -1.1211
41 Q E -0.9941
42 V E -0.3551
43 I E -0.8176
44 R E -1.2718
45 A E -1.1194
46 D E -2.0859
47 G E -1.2026
48 L E -0.5923
49 L E -0.1993
50 V E 0.0000
51 S E -0.9551
52 D E -0.6495
53 L E 0.0000
54 L E 0.0000
55 Q E -1.1406
56 A E 0.0000
57 I E 0.0000
58 I E 0.0000
59 P E 0.1349
60 L E 0.4469
61 F E 0.0000
62 E E -0.6788
63 L E -0.1940
64 D E 0.0000
65 S E -0.2303
66 Y E 0.0166
67 A E -0.1176
68 P E 0.0000
69 P E 0.0000
70 L E 0.0000
71 V E 0.0000
72 M E 0.0000
73 M E 0.0000
74 A E 0.1276
75 A E 0.2508
76 V E 1.0076
77 L E 1.3971 mutated: EE77L
78 G E 0.2564
79 D E 0.0632
80 T E -0.1313
81 L E -0.4600
82 D E -1.6947
83 P E -2.0386
84 E E -3.1244
85 V E 0.0000
86 E E -2.5230
87 R E -3.6036
88 R E -2.8138
89 Y E 0.0000
90 R E -2.4364
91 N E -2.2022
92 A E 0.0000
93 L E 0.0000
94 S E -0.2337
95 L E 1.0266
97 A E 0.4316
98 P E -0.3707
99 C E 0.0000
100 P E -0.9963
101 D E -1.9839
102 I E 0.0000
103 I E 0.0000
104 R E -0.7188
105 I E 0.0000
106 N E -0.1784
107 R E -0.1481
108 F E 0.1859
109 A E 0.0000
110 F E 0.0000
111 Y E 0.0000
112 E E 0.0000
113 R E -0.8773
114 A E 0.0000
115 Q E -1.3246
116 K E -2.0482
117 A E 0.0000
118 F E -0.7023
119 A E 0.0000
120 I E 0.0000
121 V E 0.0000
122 I E 0.0000
123 T E 0.0000
124 G E -1.2422
125 E E 0.0000
126 R E -1.8790
127 A E -1.3772
128 K E -1.0268
129 Y E 0.0000
130 G E 0.0000
131 N E 0.0000
132 I E 0.0000
133 L E 0.0000
134 L E 0.0000
135 K E -0.3720
136 K E 0.0000
137 G E 0.0000
138 V E -0.2007
139 T E -0.3795
140 P E -0.6332
1 M F 1.4332
2 L F 1.2021
3 K F -0.7074
4 T F -0.3103
5 I F 0.4528
6 S F 0.2548
7 P F 0.4694
8 L F 0.4187
9 I F 0.0000
10 S F -0.7326
11 P F -1.0874
12 E F -2.4998
13 L F 0.0000
14 L F -1.1881
15 K F -2.4013
16 V F 0.0000
17 L F 0.0000
18 A F -0.8296
19 E F -1.1715
20 M F 0.0000
21 G F 0.0000
22 H F 0.0000
23 G F -0.0821
24 D F 0.0000
25 E F 0.0000
26 I F 0.0000
27 I F 0.0000
28 F F 0.0000
29 S F 0.0000
30 D F 0.0000
31 A F -1.0864
32 H F 0.0000
33 F F 0.0000
34 P F 0.0000
35 A F 0.0000
36 H F -0.6691
37 S F -0.9250
38 M F 0.0000
39 G F -1.4557
40 P F -1.3495
41 Q F -0.9408
42 V F -0.3251
43 I F -0.8000
44 R F -1.4409
45 A F -1.0333
46 D F -2.0326
47 G F -1.3339
48 L F -0.5350
49 L F -0.2733
50 V F 0.0000
51 S F -1.1223
52 D F -0.9189
53 L F 0.0000
54 L F 0.0000
55 Q F -1.5705
56 A F 0.0000
57 I F 0.0000
58 I F -0.1046
59 P F -0.0871
60 L F 0.5147
61 F F 0.0000
62 E F -0.6512
63 L F -0.1590
64 D F 0.0000
65 S F -0.0182
66 Y F 0.3793
67 A F 0.0434
68 P F -0.2080
69 P F 0.0000
70 L F 0.0000
71 V F 0.0000
72 M F 0.0000
73 M F 0.0000
74 A F -0.0784
75 A F -0.3587
76 V F 0.0000
77 L F 0.8473 mutated: EF77L
78 G F -0.2207
79 D F -0.6814
80 T F -0.6044
81 L F -1.1461
82 D F -2.7017
83 P F -2.4519
84 E F -3.2894
85 V F 0.0000
86 E F -2.4467
87 R F -3.5434
88 R F -2.6089
89 Y F 0.0000
90 R F -2.7163
91 N F -2.5947
92 A F 0.0000
93 L F 0.0000
94 S F -1.3631
95 L F 0.0000
96 Q F -1.6845
97 A F -0.7068
98 P F -0.4685
99 C F -0.2932
100 P F -0.6359
101 D F -1.4855
102 I F -0.3769
103 I F 0.3307
104 R F -0.0994
105 I F -0.1671
106 N F -0.7431
107 R F 0.0000
108 F F -0.3210
109 A F -0.8787
110 F F 0.0000
111 Y F -1.3647
112 E F -2.6181
113 R F -2.0992
114 A F 0.0000
115 Q F -2.9189
116 K F -2.9091
117 A F 0.0000
118 F F 0.0000
119 A F 0.0000
120 I F 0.0000
121 V F 0.0000
122 I F 0.0000
123 T F 0.0000
124 G F 0.0000
125 E F 0.0000
126 R F -2.0252
127 A F -1.7845
128 K F -1.7360
129 Y F 0.0000
130 G F 0.0000
131 N F 0.0000
132 I F 0.0000
133 L F 0.0000
134 L F 0.0000
135 K F -0.3301
136 K F 0.0000
137 G F 0.0000
138 V F -0.2973
139 T F -0.4223
140 P F -0.6300
1 M G 1.2838
2 L G 0.8554
3 K G -0.8769
4 T G -0.3623
5 I G 0.4295
6 S G 0.1400
7 P G 0.4795
8 L G 0.5222
9 I G 0.0000
10 S G -0.5761
11 P G -0.9053
12 E G -1.9584
13 L G 0.0000
14 L G -1.0024
15 K G -2.2335
16 V G 0.0000
17 L G 0.0000
18 A G -0.6272
19 E G -1.0993
20 M G 0.0000
21 G G 0.0000
22 H G -0.2140
23 G G -0.2428
24 D G 0.0000
25 E G -0.6599
26 I G 0.0000
27 I G 0.0000
28 F G 0.0000
29 S G 0.0000
30 D G 0.0000
31 A G -1.1250
32 H G -0.6293
33 F G 0.0000
34 P G 0.0000
35 A G 0.0000
36 H G -0.6703
37 S G -0.8727
38 M G -1.2885
39 G G -1.3624
40 P G -1.3131
41 Q G -0.8916
42 V G -0.5210
43 I G 0.0000
44 R G -1.3273
45 A G -1.0594
46 D G -2.0511
47 G G -1.3526
48 L G -0.5110
49 L G -0.3240
50 V G 0.0000
51 S G -1.1227
52 D G -0.6775
53 L G 0.0000
54 L G 0.0000
55 Q G -1.6106
56 A G 0.0000
57 I G 0.0000
58 I G 0.0000
59 P G -0.3566
60 L G 0.3130
61 F G 0.0000
62 E G -0.6170
63 L G -0.1273
64 D G 0.0000
65 S G -0.0845
66 Y G 0.3159
67 A G 0.0474
68 P G -0.3708
69 P G 0.0000
70 L G 0.0000
71 V G 0.0000
72 M G 0.0000
73 M G 0.0000
74 A G 0.2057
75 A G 0.0406
76 V G 0.7981
77 L G 1.3754 mutated: EG77L
78 G G 0.1963
79 D G -0.1884
80 T G -0.2537
81 L G -0.6607
82 D G -1.8471
83 P G -2.0594
84 E G -3.1123
85 V G 0.0000
86 E G -2.4785
87 R G -3.6307
88 R G -2.7908
89 Y G 0.0000
90 R G -2.9182
91 N G -2.5566
92 A G 0.0000
93 L G 0.0000
94 S G -1.0524
95 L G -0.3976
96 Q G -1.0832
97 A G -0.5501
98 P G -0.8240
99 C G -0.8953
100 P G -1.0720
101 D G -1.9152
102 I G 0.0000
103 I G -0.0843
104 R G -0.5003
105 I G 0.1454
106 N G -0.0002
107 R G 0.3206
108 F G 1.3562
109 A G 0.0359
110 F G 0.0000
111 Y G -0.5306
112 E G -1.6384
113 R G -1.7363
114 A G 0.0000
115 Q G -2.6907
116 K G -2.7268
117 A G 0.0000
118 F G 0.0000
119 A G 0.0000
120 I G 0.0000
121 V G 0.0000
122 I G 0.0000
123 T G 0.0000
124 G G 0.0000
125 E G 0.0000
126 R G -2.0041
127 A G -1.6124
128 K G -1.3553
129 Y G 0.0000
130 G G 0.0000
131 N G 0.0000
132 I G 0.0000
133 L G 0.0000
134 L G 0.0000
135 K G -0.3948
136 K G 0.0000
137 G G 0.0000
138 V G -0.2835
139 T G -0.4279
140 P G -0.6049
1 M H 1.2800
2 L H 0.7417
3 K H -0.9062
4 T H -0.3658
5 I H 0.5129
6 S H 0.2584
7 P H 0.6724
8 L H 1.0210
9 I H 0.0000
10 S H -0.6129
11 P H -1.1212
12 E H -2.4278
13 L H 0.0000
14 L H -1.1851
15 K H -2.4078
16 V H 0.0000
17 L H 0.0000
18 A H -0.8038
19 E H -1.0860
20 M H 0.0000
21 G H 0.0000
22 H H 0.0000
23 G H -0.1365
24 D H 0.0000
25 E H 0.0000
26 I H 0.0000
27 I H 0.0000
28 F H 0.0000
29 S H 0.0000
30 D H 0.0000
31 A H -0.9885
32 H H -0.6123
33 F H 0.0000
34 P H 0.0000
35 A H 0.0000
36 H H -0.6533
37 S H -0.6128
38 M H 0.0000
39 G H -1.2076
40 P H -1.2020
41 Q H -1.0779
42 V H -0.3891
43 I H -0.7871
44 R H -1.2073
45 A H -0.8933
46 D H -1.7964
47 G H -1.0388
48 L H -0.3142
49 L H -0.2607
50 V H 0.0000
51 S H -1.0852
52 D H -0.7412
53 L H 0.0000
54 L H 0.0000
55 Q H -1.5051
56 A H 0.0000
57 I H 0.0000
58 I H 0.0000
59 P H -0.2552
60 L H 0.5284
61 F H 0.0000
62 E H -0.5884
63 L H -0.1940
64 D H 0.0000
65 S H -0.2934
66 Y H -0.0326
67 A H -0.1416
68 P H 0.0000
69 P H 0.0000
70 L H 0.0000
71 V H 0.0000
72 M H 0.0000
73 M H 0.0000
74 A H 0.1051
75 A H 0.1554
76 V H 0.8785
77 L H 1.2776 mutated: EH77L
78 G H 0.0819
79 D H -0.1665
80 T H -0.2239
81 L H -0.5554
82 D H -1.9114
83 P H -2.0360
84 E H -2.9705
85 V H 0.0000
86 E H -2.5350
87 R H -3.5173
88 R H -2.6181
89 Y H 0.0000
90 R H -2.5090
91 N H -2.3293
92 A H 0.0000
93 L H 0.0000
94 S H -0.9144
95 L H -0.4312
96 Q H -0.8990
97 A H -0.4820
98 P H -0.8365
99 C H 0.0000
100 P H -1.1668
101 D H -2.2651
102 I H 0.0000
103 I H 0.0000
104 R H -0.6508
105 I H 0.0000
106 N H -0.0207
107 R H -0.1741
108 F H 0.1914
109 A H 0.0000
110 F H 0.0000
111 Y H 0.0000
112 E H 0.0000
113 R H -0.7786
114 A H 0.0000
115 Q H -1.5161
116 K H -2.0368
117 A H 0.0000
118 F H -0.6405
119 A H 0.0000
120 I H 0.0000
121 V H 0.0000
122 I H 0.0000
123 T H 0.0000
124 G H 0.0000
125 E H 0.0000
126 R H -1.9289
127 A H -1.5225
128 K H -1.1651
129 Y H 0.0000
130 G H 0.0000
131 N H 0.0000
132 I H 0.0000
133 L H 0.0000
134 L H 0.0000
135 K H -0.3012
136 K H 0.0000
137 G H 0.0000
138 V H -0.3801
139 T H -0.4010
140 P H -0.6175
1 M I 1.2992
2 L I 0.9384
3 K I -0.8240
4 T I -0.3203
5 I I 0.4687
6 S I 0.1737
7 P I 0.3867
8 L I 0.4467
9 I I 0.0000
10 S I -0.6865
11 P I -1.0698
12 E I -2.3417
13 L I 0.0000
14 L I -1.0600
15 K I -2.3464
16 V I 0.0000
17 L I 0.0000
18 A I -0.8234
19 E I -1.1248
20 M I 0.0000
21 G I 0.0000
22 H I -0.2358
23 G I -0.1887
24 D I 0.0000
25 E I -0.6368
26 I I 0.0000
27 I I 0.0000
28 F I 0.0000
29 S I 0.0000
30 D I 0.0000
31 A I -1.1118
32 H I -0.6743
33 F I 0.0000
34 P I 0.0000
35 A I 0.0000
36 H I -0.5972
37 S I -0.8101
38 M I -1.3446
39 G I -1.3992
40 P I -1.2735
41 Q I -0.7945
42 V I -0.4539
43 I I -0.7661
44 R I -1.3749
45 A I -0.9975
46 D I -1.9927
47 G I -1.2936
48 L I -0.2737
49 L I -0.1091
50 V I 0.0000
51 S I 0.0000
52 D I -0.6957
53 L I 0.0000
54 L I 0.0000
55 Q I -1.0982
56 A I 0.0000
57 I I 0.0000
58 I I -0.0760
59 P I -0.1481
60 L I 0.4330
61 F I 0.0000
62 E I -0.6630
63 L I -0.2102
64 D I 0.0000
65 S I -0.2438
66 Y I -0.0396
67 A I -0.1787
68 P I -0.2760
69 P I -0.3549
70 L I 0.0000
71 V I 0.0000
72 M I 0.0000
73 M I 0.0000
74 A I 0.0108
75 A I -0.4000
76 V I 0.0000
77 L I 0.1676 mutated: EI77L
78 G I -0.1492
79 D I -0.2859
80 T I -0.5496
81 L I -1.3119
82 D I -2.7880
83 P I -2.5504
84 E I -3.1669
85 V I 0.0000
86 E I -2.7133
87 R I -3.7155
88 R I -2.6664
89 Y I 0.0000
90 R I -2.4541
91 N I -2.4607
92 A I 0.0000
93 L I 0.0000
94 S I -0.9099
95 L I -0.3076
96 Q I -1.0463
97 A I -0.5979
98 P I -0.8283
99 C I 0.0000
100 P I -0.6933
101 D I -0.9097
102 I I 0.0000
103 I I 0.1005
104 R I -0.2033
105 I I 0.0611
106 N I -0.3839
107 R I 0.0000
108 F I 0.3629
109 A I -0.5023
110 F I 0.0000
111 Y I -1.1299
112 E I -2.5448
113 R I -2.1626
114 A I 0.0000
115 Q I -2.9028
116 K I -2.9409
117 A I 0.0000
118 F I 0.0000
119 A I 0.0000
120 I I 0.0000
121 V I 0.0000
122 I I 0.0000
123 T I 0.0000
124 G I 0.0000
125 E I 0.0000
126 R I -2.0683
127 A I -1.7384
128 K I -1.6240
129 Y I 0.0000
130 G I 0.0000
131 N I 0.0000
132 I I 0.0000
133 L I 0.0000
134 L I 0.0000
135 K I -0.4311
136 K I 0.0000
137 G I 0.0000
138 V I -0.4193
139 T I -0.4584
140 P I -0.5838
1 M J 1.3116
2 L J 0.8562
3 K J -0.8513
4 T J -0.3226
5 I J 0.5681
6 S J 0.1742
7 P J 0.5419
8 L J 0.7487
9 I J 0.0000
10 S J -0.6595
11 P J -1.1148
12 E J -2.4240
13 L J 0.0000
14 L J -1.1766
15 K J -2.4256
16 V J 0.0000
17 L J 0.0000
18 A J -0.8245
19 E J -1.1554
20 M J 0.0000
21 G J 0.0000
22 H J 0.0000
23 G J -0.1178
24 D J 0.0000
25 E J -0.5535
26 I J 0.0000
27 I J 0.0000
28 F J 0.0000
29 S J 0.0000
30 D J 0.0000
31 A J -1.0834
32 H J -0.6611
33 F J 0.0000
34 P J 0.0000
35 A J 0.0000
36 H J -0.5217
37 S J -0.7031
38 M J -0.8993
39 G J -1.2281
40 P J -1.1105
41 Q J -0.8314
42 V J -0.2801
43 I J -0.8181
44 R J -1.3958
45 A J -1.1293
46 D J -2.1183
47 G J -1.2297
48 L J -0.4604
49 L J -0.2862
50 V J 0.0000
51 S J 0.0000
52 D J -0.7100
53 L J 0.0000
54 L J 0.0000
55 Q J -1.2820
56 A J 0.0000
57 I J 0.0000
58 I J 0.0000
59 P J -0.0461
60 L J 0.7665
61 F J 0.0000
62 E J -0.5026
63 L J -0.2138
64 D J 0.0000
65 S J -0.1344
66 Y J 0.3468
67 A J 0.0442
68 P J -0.4748
69 P J -0.5087
70 L J 0.0000
71 V J 0.0000
72 M J 0.0000
73 M J 0.0000
74 A J 0.3205
75 A J 0.3203
76 V J 1.1791
77 L J 1.2526 mutated: EJ77L
78 G J 0.0000
79 D J 0.0556
80 T J 0.1680
81 L J -0.1497
82 D J -1.3722
83 P J -1.6547
84 E J -2.9098
85 V J 0.0000
86 E J 0.0000
87 R J -3.3680
88 R J -2.5585
89 Y J 0.0000
90 R J -2.4163
91 N J -2.0128
92 A J 0.0000
93 L J 0.0000
94 S J -0.5662
95 L J 0.2830
96 Q J -0.6824
97 A J -0.3876
98 P J -0.2685
99 C J -0.6323
100 P J -1.0256
101 D J -1.8453
102 I J 0.0000
103 I J 0.0000
104 R J -0.3721
105 I J 0.0000
106 N J 0.2355
107 R J 0.5669
108 F J 1.3595
109 A J 0.0000
110 F J 0.0000
111 Y J 0.0169
112 E J -0.4524
113 R J 0.0000
114 A J 0.0000
115 Q J -1.9053
116 K J -2.2251
117 A J 0.0000
118 F J -0.7079
119 A J 0.0000
120 I J 0.0000
121 V J 0.0000
122 I J 0.0000
123 T J 0.0000
124 G J 0.0000
125 E J 0.0000
126 R J -1.9676
127 A J -1.5605
128 K J -1.3453
129 Y J -0.6492
130 G J 0.0000
131 N J 0.0000
132 I J 0.0000
133 L J 0.0000
134 L J 0.0000
135 K J -0.4467
136 K J -0.4451
137 G J 0.0000
138 V J -0.3392
139 T J -0.3739
140 P J -0.7013

 

Laboratory of Theory of Biopolymers 2015