Chain sequence(s) |
A: MNYEAYFRRQLDGLHREGRYRVFADLERHAGSFPRATHHRPEGAGDVTVWCSNDYLGMGQHPAVLTAMHEALDSCGAGAGGTRNIAGTNHYHVLLEQELAALHGKESALLFTSGYVSNWASLSTLASRMPGCVILSDELNHASMIEGIRHSRSETRIFAHNDPRDLERKLADLDPHAPKLVAFESVYSMDGDIAPIAEICDVADAHNAMTYLDEVHGVGLYGPNGGGIADREGISHRLTIIEGTLAKAFGVVGGYIAGSSAVCDFVRSFASGFIFSTSPPPAVAAGALASIRHLRASSAERERHQDRVARLRARLDQAGVAHMPNPSHIVPVMVGDAALCKQISDELISRYGIYVQPINYPTVPRGTERLRITPSPQHTDADIEHLVQALSEIWT B: MNYEAYFRRQLDGLHREGRYRVFADLERHAGSFPRATHHRPEGAGDVTVWCSNDYLGMGQHPAVLTAMHEALDSCGAGAGGTRNIAGTNHYHVLLEQELAALHGKESALLFTSGYVSNWASLSTLASRMPGCVILSDELNHASMIEGIRHSRSETRIFAHNDPRDLERKLADLDPHAPKLVAFESVYSMDGDIAPIAEICDVADAHNAMTYLDEVHGVGLYGPNGGGIADREGISHRLTIIEGTLAKAFGVVGGYIAGSSAVCDFVRSFASGFIFSTSPPPAVAAGALASIRHLRASSAERERHQDRVARLRARLDQAGVAHMPNPSHIVPVMVGDAALCKQISDELISRYGIYVQPINYPTVPRGTERLRITPSPQHTDADIEHLVQALSEI |
Distance of aggregation | 5 Å |
Dynamic mode | No |
Mutated residues | GA366Q, GB366Q |
Energy difference between WT (input) and mutated protein (by FoldX) | 6.13599 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure Changes in protein stability upon mutation are calculated using the FoldX forcefield. Computational prediction of protein stability is used with the intention of preventing the experimental characterization of proteins bearing mutations that significantly destabilize their structure. Mutations resulting in a predicted reduction in protein stability ≥ 1 kcal/mol are considered disruptive. |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
1 | M | A | 0.1998 | |
2 | N | A | -1.1929 | |
3 | Y | A | 0.0000 | |
4 | E | A | -1.8173 | |
5 | A | A | -0.2062 | |
6 | Y | A | 0.5801 | |
7 | F | A | 0.0000 | |
8 | R | A | -2.1774 | |
9 | R | A | -2.2552 | |
10 | Q | A | -0.6189 | |
11 | L | A | 0.0601 | |
12 | D | A | -0.4003 | |
13 | G | A | -0.3698 | |
14 | L | A | 0.0000 | |
15 | H | A | -1.3312 | |
16 | R | A | -2.3069 | |
17 | E | A | -1.8423 | |
18 | G | A | -0.5021 | |
19 | R | A | -0.2096 | |
20 | Y | A | 0.1641 | |
21 | R | A | 0.1790 | |
22 | V | A | 1.7893 | |
23 | F | A | 0.6079 | |
24 | A | A | -0.0261 | |
25 | D | A | -0.4583 | |
26 | L | A | 0.0000 | |
27 | E | A | -0.2411 | |
28 | R | A | 0.0000 | |
29 | H | A | -0.4166 | |
30 | A | A | -0.1486 | |
31 | G | A | -0.4735 | |
32 | S | A | -0.1381 | |
33 | F | A | 0.0000 | |
34 | P | A | -0.2691 | |
35 | R | A | -1.2882 | |
36 | A | A | 0.0000 | |
37 | T | A | -0.2207 | |
38 | H | A | 0.0000 | |
39 | H | A | -0.4898 | |
40 | R | A | -1.3930 | |
41 | P | A | -0.8134 | |
42 | E | A | -1.9512 | |
43 | G | A | -0.7886 | |
44 | A | A | -0.1329 | |
45 | G | A | -0.6490 | |
46 | D | A | -1.8513 | |
47 | V | A | 0.0000 | |
48 | T | A | -0.1494 | |
49 | V | A | 0.0000 | |
50 | W | A | 0.0000 | |
51 | C | A | 0.0000 | |
52 | S | A | -0.0223 | |
53 | N | A | 0.0000 | |
54 | D | A | 0.0000 | |
55 | Y | A | 0.0000 | |
56 | L | A | 0.0000 | |
57 | G | A | 0.0000 | |
58 | M | A | 0.0000 | |
59 | G | A | 0.0000 | |
60 | Q | A | -0.1912 | |
61 | H | A | -0.2397 | |
62 | P | A | -0.2787 | |
63 | A | A | -0.0149 | |
64 | V | A | 0.0000 | |
65 | L | A | 0.1497 | |
66 | T | A | -0.0334 | |
67 | A | A | -0.0023 | |
68 | M | A | 0.0000 | |
69 | H | A | -0.5412 | |
70 | E | A | -1.8581 | |
71 | A | A | 0.0000 | |
72 | L | A | 0.0000 | |
73 | D | A | -1.8227 | |
74 | S | A | -0.5070 | |
75 | C | A | 0.0000 | |
76 | G | A | 0.0000 | |
77 | A | A | 0.0000 | |
78 | G | A | 0.0000 | |
79 | A | A | 0.0000 | |
80 | G | A | 0.0000 | |
81 | G | A | 0.0000 | |
82 | T | A | -0.0077 | |
83 | R | A | 0.0000 | |
84 | N | A | 0.0000 | |
85 | I | A | 0.0000 | |
86 | A | A | 0.0000 | |
87 | G | A | 0.0000 | |
88 | T | A | 0.0000 | |
89 | N | A | 0.0000 | |
90 | H | A | -0.4197 | |
91 | Y | A | 0.0924 | |
92 | H | A | 0.0000 | |
93 | V | A | 0.7851 | |
94 | L | A | 0.8617 | |
95 | L | A | 0.0000 | |
96 | E | A | 0.0000 | |
97 | Q | A | -1.2344 | |
98 | E | A | -0.4161 | |
99 | L | A | 0.0000 | |
100 | A | A | 0.0000 | |
101 | A | A | -0.0018 | |
102 | L | A | 0.0000 | |
103 | H | A | 0.0000 | |
104 | G | A | -0.5070 | |
105 | K | A | -0.6770 | |
106 | E | A | -1.8812 | |
107 | S | A | -0.3821 | |
108 | A | A | 0.0000 | |
109 | L | A | 0.0000 | |
110 | L | A | 0.0000 | |
111 | F | A | 0.0000 | |
112 | T | A | -0.0085 | |
113 | S | A | 0.0000 | |
114 | G | A | -0.0459 | |
115 | Y | A | 0.0000 | |
116 | V | A | 0.0000 | |
117 | S | A | 0.0000 | |
118 | N | A | 0.0000 | |
119 | W | A | 0.0000 | |
120 | A | A | 0.0000 | |
121 | S | A | 0.0000 | |
122 | L | A | 0.0000 | |
123 | S | A | 0.0000 | |
124 | T | A | 0.0000 | |
125 | L | A | 0.0000 | |
126 | A | A | -0.0315 | |
127 | S | A | -0.2116 | |
128 | R | A | 0.0000 | |
129 | M | A | 0.0000 | |
130 | P | A | -0.3079 | |
131 | G | A | -0.5071 | |
132 | C | A | 0.0000 | |
133 | V | A | 0.0000 | |
134 | I | A | 0.0000 | |
135 | L | A | 0.0000 | |
136 | S | A | 0.0000 | |
137 | D | A | 0.0000 | |
138 | E | A | -1.5287 | |
139 | L | A | 0.2235 | |
140 | N | A | 0.0000 | |
141 | H | A | -0.2014 | |
142 | A | A | 0.0190 | |
143 | S | A | 0.0000 | |
144 | M | A | 0.0000 | |
145 | I | A | 0.4172 | |
146 | E | A | -0.1108 | |
147 | G | A | 0.0000 | |
148 | I | A | 0.0000 | |
149 | R | A | -1.7503 | |
150 | H | A | -0.4685 | |
151 | S | A | -0.4264 | |
152 | R | A | -1.8727 | |
153 | S | A | -0.7431 | |
154 | E | A | -1.7230 | |
155 | T | A | -0.4600 | |
156 | R | A | -0.4847 | |
157 | I | A | 1.0225 | |
158 | F | A | 0.0000 | |
159 | A | A | -0.0115 | |
160 | H | A | -0.2691 | |
161 | N | A | -0.5070 | |
162 | D | A | -0.6822 | |
163 | P | A | -0.4796 | |
164 | R | A | -1.9138 | |
165 | D | A | -0.6857 | |
166 | L | A | 0.0000 | |
167 | E | A | -1.1730 | |
168 | R | A | -2.0739 | |
169 | K | A | -0.7599 | |
170 | L | A | 0.0000 | |
171 | A | A | -0.2650 | |
172 | D | A | -1.7420 | |
173 | L | A | -0.4295 | |
174 | D | A | -1.7150 | |
175 | P | A | -0.7365 | |
176 | H | A | -1.0345 | |
177 | A | A | -0.1709 | |
178 | P | A | 0.0000 | |
179 | K | A | 0.0000 | |
180 | L | A | 0.0000 | |
181 | V | A | 0.0000 | |
182 | A | A | 0.0000 | |
183 | F | A | 0.0000 | |
184 | E | A | 0.0000 | |
185 | S | A | 0.0000 | |
186 | V | A | 0.0000 | |
187 | Y | A | 0.0000 | |
188 | S | A | -0.0009 | |
189 | M | A | 0.0371 | |
190 | D | A | -0.4366 | |
191 | G | A | 0.0000 | |
192 | D | A | -0.3802 | |
193 | I | A | 0.3709 | |
194 | A | A | 0.0000 | |
195 | P | A | -0.0409 | |
196 | I | A | 0.0000 | |
197 | A | A | -0.2577 | |
198 | E | A | -1.5998 | |
199 | I | A | 0.0000 | |
200 | C | A | 0.0000 | |
201 | D | A | -1.7894 | |
202 | V | A | 0.0000 | |
203 | A | A | 0.0000 | |
204 | D | A | -1.7788 | |
205 | A | A | -0.3167 | |
206 | H | A | -0.4365 | |
207 | N | A | -0.9349 | |
208 | A | A | -0.1547 | |
209 | M | A | 0.0000 | |
210 | T | A | 0.0000 | |
211 | Y | A | 0.0000 | |
212 | L | A | 0.0000 | |
213 | D | A | 0.0000 | |
214 | E | A | 0.0000 | |
215 | V | A | 0.1727 | |
216 | H | A | 0.0000 | |
217 | G | A | 0.0000 | |
218 | V | A | 0.0000 | |
219 | G | A | 0.0000 | |
220 | L | A | 0.0000 | |
221 | Y | A | 0.0000 | |
222 | G | A | 0.0000 | |
223 | P | A | -0.2946 | |
224 | N | A | -0.3361 | |
225 | G | A | 0.0000 | |
226 | G | A | 0.0000 | |
227 | G | A | 0.0000 | |
228 | I | A | 0.0000 | |
229 | A | A | 0.0000 | |
230 | D | A | -0.8553 | |
231 | R | A | -2.2581 | |
232 | E | A | -2.2360 | |
233 | G | A | -0.8413 | |
234 | I | A | 0.0000 | |
235 | S | A | -0.2100 | |
236 | H | A | -1.3273 | |
237 | R | A | -2.0223 | |
238 | L | A | 0.0000 | |
239 | T | A | -0.0245 | |
240 | I | A | 0.0000 | |
241 | I | A | 0.0000 | |
242 | E | A | 0.0000 | |
243 | G | A | 0.0000 | |
244 | T | A | 0.0000 | |
245 | L | A | 0.0000 | |
246 | A | A | 0.0000 | |
247 | K | A | -0.2126 | |
248 | A | A | 0.0000 | |
249 | F | A | 0.0000 | |
250 | G | A | 0.0000 | |
251 | V | A | 0.0000 | |
252 | V | A | 0.0000 | |
253 | G | A | 0.0000 | |
254 | G | A | 0.0000 | |
255 | Y | A | 0.0000 | |
256 | I | A | 0.0000 | |
257 | A | A | 0.0000 | |
258 | G | A | 0.0000 | |
259 | S | A | -0.2803 | |
260 | S | A | -0.2065 | |
261 | A | A | -0.0234 | |
262 | V | A | 0.0000 | |
263 | C | A | 0.0000 | |
264 | D | A | -0.3060 | |
265 | F | A | 0.0000 | |
266 | V | A | 0.0000 | |
267 | R | A | -0.2361 | |
268 | S | A | 0.0449 | |
269 | F | A | 0.6447 | |
270 | A | A | 0.0000 | |
271 | S | A | -0.0368 | |
272 | G | A | 0.0000 | |
273 | F | A | 0.0000 | |
274 | I | A | 0.2359 | |
275 | F | A | 0.2621 | |
276 | S | A | 0.0196 | |
277 | T | A | 0.0000 | |
278 | S | A | 0.0000 | |
279 | P | A | 0.0000 | |
280 | P | A | 0.0000 | |
281 | P | A | 0.0000 | |
282 | A | A | 0.0000 | |
283 | V | A | 0.0000 | |
284 | A | A | 0.0000 | |
285 | A | A | 0.0064 | |
286 | G | A | 0.0000 | |
287 | A | A | 0.0000 | |
288 | L | A | 0.0000 | |
289 | A | A | 0.0069 | |
290 | S | A | 0.0000 | |
291 | I | A | 0.0000 | |
292 | R | A | -1.8747 | |
293 | H | A | -0.5039 | |
294 | L | A | 0.0000 | |
295 | R | A | -0.4713 | |
296 | A | A | -0.0847 | |
297 | S | A | -0.3277 | |
298 | S | A | -0.2511 | |
299 | A | A | 0.0000 | |
300 | E | A | -1.1348 | |
301 | R | A | -2.0436 | |
302 | E | A | -0.7235 | |
303 | R | A | -0.4226 | |
304 | H | A | 0.0000 | |
305 | Q | A | -1.1477 | |
306 | D | A | -2.0152 | |
307 | R | A | -0.7458 | |
308 | V | A | 0.0000 | |
309 | A | A | -0.1942 | |
310 | R | A | -1.3595 | |
311 | L | A | 0.0000 | |
312 | R | A | -1.2604 | |
313 | A | A | -0.4118 | |
314 | R | A | -1.3105 | |
315 | L | A | 0.0000 | |
316 | D | A | -2.0047 | |
317 | Q | A | -1.6354 | |
318 | A | A | -0.2403 | |
319 | G | A | -0.4124 | |
320 | V | A | 0.1609 | |
321 | A | A | 0.0803 | |
322 | H | A | -0.0663 | |
323 | M | A | 0.1741 | |
324 | P | A | -0.1360 | |
325 | N | A | -0.4115 | |
326 | P | A | -0.3135 | |
327 | S | A | -0.0684 | |
328 | H | A | 0.0000 | |
329 | I | A | 0.0000 | |
330 | V | A | 0.0000 | |
331 | P | A | 0.0000 | |
332 | V | A | 0.0000 | |
333 | M | A | 0.3628 | |
334 | V | A | 0.3335 | |
335 | G | A | -0.4439 | |
336 | D | A | -1.1678 | |
337 | A | A | 0.0000 | |
338 | A | A | 0.2595 | |
339 | L | A | 1.0023 | |
340 | C | A | 0.0000 | |
341 | K | A | -0.5747 | |
342 | Q | A | -1.0902 | |
343 | I | A | 0.0000 | |
344 | S | A | 0.0000 | |
345 | D | A | -1.9338 | |
346 | E | A | -1.1300 | |
347 | L | A | 0.0000 | |
348 | I | A | 0.1599 | |
349 | S | A | -0.5170 | |
350 | R | A | -1.8463 | |
351 | Y | A | -0.1443 | |
352 | G | A | -0.0157 | |
353 | I | A | 0.0000 | |
354 | Y | A | 0.0000 | |
355 | V | A | 0.0000 | |
356 | Q | A | 0.0000 | |
357 | P | A | -0.0273 | |
358 | I | A | 0.0000 | |
359 | N | A | 0.0000 | |
360 | Y | A | 0.7466 | |
361 | P | A | 0.1156 | |
362 | T | A | 0.0562 | |
363 | V | A | 0.0000 | |
364 | P | A | -0.4296 | |
365 | R | A | -1.8134 | |
366 | Q | A | -1.5029 | mutated: GA366Q |
367 | T | A | -0.2467 | |
368 | E | A | 0.0000 | |
369 | R | A | 0.0000 | |
370 | L | A | 0.0000 | |
371 | R | A | 0.0000 | |
372 | I | A | 0.0000 | |
373 | T | A | 0.0000 | |
374 | P | A | 0.0000 | |
375 | S | A | 0.0000 | |
376 | P | A | -0.1461 | |
377 | Q | A | -0.5170 | |
378 | H | A | 0.0000 | |
379 | T | A | -0.3242 | |
380 | D | A | -1.4625 | |
381 | A | A | -0.5100 | |
382 | D | A | -0.7744 | |
383 | I | A | 0.0000 | |
384 | E | A | -1.9656 | |
385 | H | A | -0.9437 | |
386 | L | A | 0.0000 | |
387 | V | A | 0.0000 | |
388 | Q | A | -1.1983 | |
389 | A | A | 0.0000 | |
390 | L | A | 0.0000 | |
391 | S | A | -0.5081 | |
392 | E | A | -1.7981 | |
393 | I | A | 0.1197 | |
394 | W | A | 0.8660 | |
395 | T | A | 0.0732 | |
1 | M | B | 0.7115 | |
2 | N | B | -1.0813 | |
3 | Y | B | -0.4296 | |
4 | E | B | -1.7937 | |
5 | A | B | -0.2302 | |
6 | Y | B | 0.4667 | |
7 | F | B | 0.0000 | |
8 | R | B | -2.1772 | |
9 | R | B | -2.2242 | |
10 | Q | B | -0.5675 | |
11 | L | B | 0.0869 | |
12 | D | B | -0.3066 | |
13 | G | B | -0.4372 | |
14 | L | B | 0.0000 | |
15 | H | B | -1.3451 | |
16 | R | B | -2.3714 | |
17 | E | B | -2.1946 | |
18 | G | B | -0.7095 | |
19 | R | B | -0.2748 | |
20 | Y | B | 0.2233 | |
21 | R | B | 0.1875 | |
22 | V | B | 1.8090 | |
23 | F | B | 0.7178 | |
24 | A | B | 0.0401 | |
25 | D | B | -0.2136 | |
26 | L | B | 0.0000 | |
27 | E | B | -0.4623 | |
28 | R | B | 0.0000 | |
29 | H | B | -0.5003 | |
30 | A | B | -0.1610 | |
31 | G | B | -0.4941 | |
32 | S | B | -0.2513 | |
33 | F | B | 0.0000 | |
34 | P | B | -0.1380 | |
35 | R | B | -0.6222 | |
36 | A | B | 0.0000 | |
37 | T | B | -0.2003 | |
38 | H | B | 0.0000 | |
39 | H | B | -0.8320 | |
40 | R | B | -0.9642 | |
41 | P | B | -0.7257 | |
42 | E | B | -1.9127 | |
43 | G | B | -0.5762 | |
44 | A | B | -0.0987 | |
45 | G | B | -0.4945 | |
46 | D | B | -1.8229 | |
47 | V | B | 0.0000 | |
48 | T | B | 0.0000 | |
49 | V | B | 0.0000 | |
50 | W | B | 0.0000 | |
51 | C | B | 0.0000 | |
52 | S | B | -0.0235 | |
53 | N | B | 0.0000 | |
54 | D | B | 0.0000 | |
55 | Y | B | 0.0000 | |
56 | L | B | 0.0000 | |
57 | G | B | 0.0000 | |
58 | M | B | 0.0000 | |
59 | G | B | 0.0000 | |
60 | Q | B | -0.1917 | |
61 | H | B | -0.2341 | |
62 | P | B | -0.2776 | |
63 | A | B | -0.0140 | |
64 | V | B | 0.0000 | |
65 | L | B | 0.1543 | |
66 | T | B | -0.0210 | |
67 | A | B | 0.0008 | |
68 | M | B | 0.0000 | |
69 | H | B | -0.5307 | |
70 | E | B | -1.8564 | |
71 | A | B | 0.0000 | |
72 | L | B | 0.0000 | |
73 | D | B | -1.8075 | |
74 | S | B | -0.4234 | |
75 | C | B | 0.0000 | |
76 | G | B | 0.0000 | |
77 | A | B | 0.0000 | |
78 | G | B | 0.0000 | |
79 | A | B | 0.0000 | |
80 | G | B | 0.0000 | |
81 | G | B | 0.0000 | |
82 | T | B | -0.0093 | |
83 | R | B | 0.0000 | |
84 | N | B | 0.0000 | |
85 | I | B | 0.0000 | |
86 | A | B | 0.0000 | |
87 | G | B | 0.0000 | |
88 | T | B | 0.0000 | |
89 | N | B | 0.0000 | |
90 | H | B | -0.2656 | |
91 | Y | B | 0.1542 | |
92 | H | B | 0.0000 | |
93 | V | B | 0.8460 | |
94 | L | B | 0.9556 | |
95 | L | B | 0.0000 | |
96 | E | B | -0.4076 | |
97 | Q | B | -1.2965 | |
98 | E | B | -0.5698 | |
99 | L | B | 0.0000 | |
100 | A | B | 0.0000 | |
101 | A | B | -0.0211 | |
102 | L | B | 0.0000 | |
103 | H | B | 0.0000 | |
104 | G | B | -0.5135 | |
105 | K | B | -0.6940 | |
106 | E | B | -1.8841 | |
107 | S | B | -0.3714 | |
108 | A | B | 0.0000 | |
109 | L | B | 0.0000 | |
110 | L | B | 0.0000 | |
111 | F | B | 0.0000 | |
112 | T | B | -0.0082 | |
113 | S | B | 0.0000 | |
114 | G | B | 0.0000 | |
115 | Y | B | 0.0000 | |
116 | V | B | 0.0000 | |
117 | S | B | 0.0000 | |
118 | N | B | 0.0000 | |
119 | W | B | 0.0000 | |
120 | A | B | 0.0000 | |
121 | S | B | 0.0000 | |
122 | L | B | 0.0000 | |
123 | S | B | 0.0000 | |
124 | T | B | 0.0000 | |
125 | L | B | 0.0000 | |
126 | A | B | -0.0305 | |
127 | S | B | -0.2115 | |
128 | R | B | 0.0000 | |
129 | M | B | 0.0000 | |
130 | P | B | -0.3401 | |
131 | G | B | -0.5129 | |
132 | C | B | 0.0000 | |
133 | V | B | 0.0000 | |
134 | I | B | 0.0000 | |
135 | L | B | 0.0000 | |
136 | S | B | 0.0000 | |
137 | D | B | 0.0000 | |
138 | E | B | -1.3186 | |
139 | L | B | 0.2075 | |
140 | N | B | 0.0000 | |
141 | H | B | -0.2297 | |
142 | A | B | 0.0102 | |
143 | S | B | 0.0000 | |
144 | M | B | 0.0000 | |
145 | I | B | 0.3642 | |
146 | E | B | -0.2579 | |
147 | G | B | 0.0000 | |
148 | I | B | 0.0000 | |
149 | R | B | -1.5367 | |
150 | H | B | 0.0000 | |
151 | S | B | -0.4018 | |
152 | R | B | -1.8871 | |
153 | S | B | -0.8285 | |
154 | E | B | -1.8158 | |
155 | T | B | -0.4763 | |
156 | R | B | -0.6311 | |
157 | I | B | 0.6827 | |
158 | F | B | 0.0000 | |
159 | A | B | -0.0093 | |
160 | H | B | -0.2538 | |
161 | N | B | -0.4838 | |
162 | D | B | -0.6620 | |
163 | P | B | -0.4727 | |
164 | R | B | -1.8919 | |
165 | D | B | -0.5703 | |
166 | L | B | 0.0000 | |
167 | E | B | -1.3360 | |
168 | R | B | -2.1385 | |
169 | K | B | -0.9498 | |
170 | L | B | 0.0000 | |
171 | A | B | -0.2633 | |
172 | D | B | -1.7417 | |
173 | L | B | -0.4499 | |
174 | D | B | -1.7970 | |
175 | P | B | -0.7497 | |
176 | H | B | -1.0351 | |
177 | A | B | -0.1726 | |
178 | P | B | 0.0000 | |
179 | K | B | 0.0000 | |
180 | L | B | 0.0000 | |
181 | V | B | 0.0000 | |
182 | A | B | 0.0000 | |
183 | F | B | 0.0000 | |
184 | E | B | 0.0000 | |
185 | S | B | 0.0000 | |
186 | V | B | 0.0000 | |
187 | Y | B | 0.0000 | |
188 | S | B | -0.0029 | |
189 | M | B | 0.0408 | |
190 | D | B | -0.3695 | |
191 | G | B | 0.0000 | |
192 | D | B | -0.3638 | |
193 | I | B | 0.3049 | |
194 | A | B | 0.0000 | |
195 | P | B | -0.0462 | |
196 | I | B | 0.0000 | |
197 | A | B | -0.2199 | |
198 | E | B | -1.4109 | |
199 | I | B | 0.0000 | |
200 | C | B | 0.0000 | |
201 | D | B | -1.7894 | |
202 | V | B | 0.0000 | |
203 | A | B | 0.0000 | |
204 | D | B | -1.7788 | |
205 | A | B | -0.3110 | |
206 | H | B | -0.4732 | |
207 | N | B | -1.3176 | |
208 | A | B | -0.2245 | |
209 | M | B | 0.0000 | |
210 | T | B | 0.0000 | |
211 | Y | B | 0.0000 | |
212 | L | B | 0.0000 | |
213 | D | B | 0.0000 | |
214 | E | B | 0.0000 | |
215 | V | B | 0.0000 | |
216 | H | B | 0.0000 | |
217 | G | B | 0.0000 | |
218 | V | B | 0.0000 | |
219 | G | B | 0.0000 | |
220 | L | B | 0.0000 | |
221 | Y | B | 0.0000 | |
222 | G | B | 0.0000 | |
223 | P | B | -0.2963 | |
224 | N | B | -0.3979 | |
225 | G | B | 0.0000 | |
226 | G | B | 0.0000 | |
227 | G | B | 0.0000 | |
228 | I | B | 0.0000 | |
229 | A | B | 0.0000 | |
230 | D | B | -0.7074 | |
231 | R | B | -2.1724 | |
232 | E | B | -2.2217 | |
233 | G | B | -0.8253 | |
234 | I | B | 0.0000 | |
235 | S | B | -0.2133 | |
236 | H | B | -1.3253 | |
237 | R | B | -2.0121 | |
238 | L | B | 0.0000 | |
239 | T | B | -0.0225 | |
240 | I | B | 0.0000 | |
241 | I | B | 0.0000 | |
242 | E | B | 0.0000 | |
243 | G | B | 0.0000 | |
244 | T | B | 0.0000 | |
245 | L | B | 0.0000 | |
246 | A | B | 0.0000 | |
247 | K | B | -0.2061 | |
248 | A | B | 0.0000 | |
249 | F | B | 0.0000 | |
250 | G | B | 0.0000 | |
251 | V | B | 0.0000 | |
252 | V | B | 0.0000 | |
253 | G | B | 0.0000 | |
254 | G | B | 0.0000 | |
255 | Y | B | 0.0000 | |
256 | I | B | 0.0000 | |
257 | A | B | 0.0000 | |
258 | G | B | 0.0000 | |
259 | S | B | -0.2911 | |
260 | S | B | -0.1496 | |
261 | A | B | -0.0083 | |
262 | V | B | 0.0000 | |
263 | C | B | 0.0000 | |
264 | D | B | -0.2919 | |
265 | F | B | 0.0000 | |
266 | V | B | 0.0000 | |
267 | R | B | -0.2098 | |
268 | S | B | 0.0351 | |
269 | F | B | 0.5537 | |
270 | A | B | 0.0000 | |
271 | S | B | -0.0376 | |
272 | G | B | 0.0000 | |
273 | F | B | 0.0000 | |
274 | I | B | 0.0000 | |
275 | F | B | 0.2253 | |
276 | S | B | 0.0193 | |
277 | T | B | -0.0135 | |
278 | S | B | 0.0000 | |
279 | P | B | 0.0000 | |
280 | P | B | 0.0000 | |
281 | P | B | 0.0000 | |
282 | A | B | 0.0000 | |
283 | V | B | 0.0000 | |
284 | A | B | 0.0000 | |
285 | A | B | 0.0000 | |
286 | G | B | 0.0000 | |
287 | A | B | 0.0000 | |
288 | L | B | 0.2474 | |
289 | A | B | 0.0524 | |
290 | S | B | 0.0000 | |
291 | I | B | 0.0000 | |
292 | R | B | -1.8692 | |
293 | H | B | -0.4751 | |
294 | L | B | 0.0000 | |
295 | R | B | -0.8175 | |
296 | A | B | -0.1630 | |
297 | S | B | -0.4167 | |
298 | S | B | -0.2323 | |
299 | A | B | 0.0000 | |
300 | E | B | -1.9731 | |
301 | R | B | -2.2052 | |
302 | E | B | -0.8140 | |
303 | R | B | -0.6748 | |
304 | H | B | 0.0000 | |
305 | Q | B | -1.4374 | |
306 | D | B | -2.0747 | |
307 | R | B | -0.7863 | |
308 | V | B | 0.0000 | |
309 | A | B | -0.2698 | |
310 | R | B | -1.7860 | |
311 | L | B | 0.0000 | |
312 | R | B | -1.2819 | |
313 | A | B | -0.4299 | |
314 | R | B | -1.3460 | |
315 | L | B | 0.0000 | |
316 | D | B | -2.0049 | |
317 | Q | B | -1.6370 | |
318 | A | B | -0.2470 | |
319 | G | B | -0.3540 | |
320 | V | B | 0.4787 | |
321 | A | B | 0.1382 | |
322 | H | B | -0.0477 | |
323 | M | B | 0.1336 | |
324 | P | B | -0.1660 | |
325 | N | B | -0.3985 | |
326 | P | B | -0.3109 | |
327 | S | B | -0.0688 | |
328 | H | B | 0.0000 | |
329 | I | B | 0.0000 | |
330 | V | B | 0.0000 | |
331 | P | B | 0.0000 | |
332 | V | B | 0.2326 | |
333 | M | B | 0.4877 | |
334 | V | B | 0.3746 | |
335 | G | B | -0.5045 | |
336 | D | B | -1.3272 | |
337 | A | B | 0.0000 | |
338 | A | B | 0.2769 | |
339 | L | B | 1.1197 | |
340 | C | B | 0.0000 | |
341 | K | B | -0.7738 | |
342 | Q | B | -0.9366 | |
343 | I | B | 0.1874 | |
344 | S | B | 0.0000 | |
345 | D | B | -0.8588 | |
346 | E | B | -0.9650 | |
347 | L | B | 0.0000 | |
348 | I | B | 0.2002 | |
349 | S | B | -0.4895 | |
350 | R | B | -1.8294 | |
351 | Y | B | -0.0776 | |
352 | G | B | -0.0006 | |
353 | I | B | 0.0000 | |
354 | Y | B | 0.0000 | |
355 | V | B | 0.0000 | |
356 | Q | B | 0.0000 | |
357 | P | B | -0.0322 | |
358 | I | B | 0.0000 | |
359 | N | B | 0.0000 | |
360 | Y | B | 0.6823 | |
361 | P | B | 0.0891 | |
362 | T | B | 0.0466 | |
363 | V | B | 0.0000 | |
364 | P | B | -0.2377 | |
365 | R | B | -0.6465 | |
366 | Q | B | -1.2956 | mutated: GB366Q |
367 | T | B | -0.2578 | |
368 | E | B | 0.0000 | |
369 | R | B | 0.0000 | |
370 | L | B | 0.0000 | |
371 | R | B | 0.0000 | |
372 | I | B | 0.0000 | |
373 | T | B | 0.0000 | |
374 | P | B | 0.0000 | |
375 | S | B | 0.0000 | |
376 | P | B | -0.1421 | |
377 | Q | B | -0.5617 | |
378 | H | B | 0.0000 | |
379 | T | B | -0.3410 | |
380 | D | B | -1.6771 | |
381 | A | B | -0.2781 | |
382 | D | B | -0.2640 | |
383 | I | B | 0.0000 | |
384 | E | B | -1.9388 | |
385 | H | B | -1.0105 | |
386 | L | B | 0.0000 | |
387 | V | B | 0.0000 | |
388 | Q | B | -1.1983 | |
389 | A | B | 0.0000 | |
390 | L | B | 0.1593 | |
391 | S | B | -0.5051 | |
392 | E | B | -1.5714 | |
393 | I | B | 1.2842 |