Project name: 1rf8_a1_Valen

Chain sequence(s)	A: MSVEEVSKKFEENVSVDDTTATPKTVLSDSAHFDVKHPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRNDVRPEWEDEANAKGGKWSFQLCGKGADIDELWLCTLLAVIGETIDEDDSQINGVVLSIRKGGNKFALWTKCEDKEPLLRIGGKFKQVLKLTDDGHLEFFPHCSANGRHPQPSITL
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6326
• Maximal score value: 1.6259
• Average score: -0.9265
• Total score value: -197.3422

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	1.3666
2	S	A	0.6873
3	V	A	0.7724
4	E	A	-1.4708
5	E	A	-1.6581
6	V	A	-0.5874
7	S	A	-1.2838
8	K	A	-2.4404
9	K	A	-2.3837
10	F	A	-0.8527
11	E	A	-2.6591
12	E	A	-2.8061
13	N	A	-1.3963
14	V	A	0.9563
15	S	A	0.5519
16	V	A	0.5944
17	D	A	-1.8768
18	D	A	-2.3350
19	T	A	-1.1458
20	T	A	-0.8944
21	A	A	-0.3153
22	T	A	-0.6374
23	P	A	-1.0414
24	K	A	-1.1582
25	T	A	0.0086
26	V	A	0.8274
27	L	A	1.6259
28	S	A	0.4252
29	D	A	-0.0382
30	S	A	0.2430
31	A	A	-0.1585
32	H	A	-0.5026
33	F	A	0.2520
34	D	A	-1.6396
35	V	A	-1.0704
36	K	A	-1.8359
37	H	A	-1.0767
38	P	A	-0.8086
39	L	A	-0.8090
40	N	A	-1.3367
41	T	A	0.0000
42	K	A	-2.2835
43	W	A	0.0000
44	T	A	0.0000
45	L	A	0.0000
46	W	A	0.0000
47	Y	A	0.0000
48	T	A	0.0000
49	K	A	-2.2411
50	P	A	-1.8323
51	A	A	-0.7799
52	V	A	-0.4620
53	D	A	-2.4910
54	K	A	-2.2554
55	S	A	-1.9292
56	E	A	-2.3952
57	S	A	-1.8235
58	W	A	-1.4013
59	S	A	-1.5773
60	D	A	-2.4709
61	L	A	0.0000
62	L	A	0.0000
63	R	A	-2.2325
64	P	A	-0.6149
65	V	A	0.6767
66	T	A	0.4955
67	S	A	0.4055
68	F	A	0.8569
69	Q	A	-0.5724
70	T	A	-0.7253
71	V	A	-0.3479
72	E	A	-0.8726
73	E	A	-0.6030
74	F	A	0.0000
75	W	A	-0.1437
76	A	A	-0.4844
77	I	A	-0.0296
78	I	A	-0.1825
79	Q	A	-0.8858
80	N	A	-0.8813
81	I	A	0.5337
82	P	A	0.0000
83	E	A	-1.2741
84	P	A	0.0000
85	H	A	-1.8110
86	E	A	-1.7414
87	L	A	-0.7400
88	P	A	-1.3678
89	L	A	-2.0574
90	K	A	-2.9971
91	S	A	0.0000
92	D	A	-1.3440
93	Y	A	0.0000
94	H	A	0.0000
95	V	A	0.0000
96	F	A	0.0000
97	R	A	-2.2668
98	N	A	-2.6524
99	D	A	-2.2437
100	V	A	-1.9699
101	R	A	-2.6666
102	P	A	-1.7061
103	E	A	0.0000
104	W	A	-1.7511
105	E	A	-3.3128
106	D	A	-2.6974
107	E	A	0.0000
108	A	A	0.0000
109	N	A	-2.2797
110	A	A	-1.4648
111	K	A	0.0000
112	G	A	-1.1122
113	G	A	0.0000
114	K	A	-0.0962
115	W	A	0.0000
116	S	A	0.0000
117	F	A	0.0000
118	Q	A	-0.8323
119	L	A	0.0000
120	C	A	-0.4469
121	G	A	-1.3017
122	K	A	-1.7965
123	G	A	-1.9599
124	A	A	-1.7171
125	D	A	-2.2126
126	I	A	0.0000
127	D	A	-1.4908
128	E	A	-1.9067
129	L	A	-0.8572
130	W	A	0.0000
131	L	A	0.0000
132	C	A	0.3910
133	T	A	0.0000
134	L	A	0.0000
135	L	A	0.1569
136	A	A	-0.4746
137	V	A	0.0000
138	I	A	0.0000
139	G	A	0.0000
140	E	A	-2.1482
141	T	A	0.0000
142	I	A	-0.3381
143	D	A	-2.5529
144	E	A	-3.0970
145	D	A	-2.4036
146	D	A	0.0000
147	S	A	-2.2150
148	Q	A	-1.9178
149	I	A	0.0000
150	N	A	0.0000
151	G	A	0.0000
152	V	A	0.0000
153	V	A	0.0000
154	L	A	0.0000
155	S	A	-1.0350
156	I	A	0.0000
157	R	A	-3.5315
158	K	A	-2.9712
159	G	A	-1.8834
160	G	A	0.0000
161	N	A	0.0000
162	K	A	-1.2111
163	F	A	0.0000
164	A	A	0.0000
165	L	A	0.0000
166	W	A	0.0000
167	T	A	0.0000
168	K	A	-1.9027
169	C	A	-2.1290
170	E	A	-3.3262
171	D	A	-3.6326
172	K	A	-3.2639
173	E	A	-3.2438
174	P	A	-2.3629
175	L	A	0.0000
176	L	A	-1.0538
177	R	A	-2.0877
178	I	A	-1.1629
179	G	A	0.0000
180	G	A	-1.3133
181	K	A	-1.8578
182	F	A	0.0000
183	K	A	-2.1005
184	Q	A	-2.4161
185	V	A	0.0000
186	L	A	0.0000
187	K	A	-1.8514
188	L	A	-1.7072
189	T	A	-1.9888
190	D	A	-2.7755
191	D	A	-2.7762
192	G	A	-1.4789
193	H	A	-1.1038
194	L	A	0.0000
195	E	A	0.0000
196	F	A	0.0000
197	F	A	0.0590
198	P	A	-0.5791
199	H	A	-1.4291
200	C	A	-0.5489
201	S	A	0.0000
202	A	A	0.0000
203	N	A	-3.1415
204	G	A	-2.4319
205	R	A	-3.2284
206	H	A	-2.5161
207	P	A	-1.7911
208	Q	A	-1.5314
209	P	A	-0.7036
210	S	A	0.3155
211	I	A	1.3301
212	T	A	0.8069
213	L	A	0.3462