Project name: 6b9y:A
Status: done
submitted: 2019-03-21 13:12:22, status changed: 2019-03-21 13:24:53
Settings
Chain sequence(s)
|
A: DIQMTQSPIILLSASVGDRVTITCRASQDVNTAVAWYQQRRTNGSPRLLIIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDEADYYCQQHYTTPPTFGAGTKVEIKRTVAAPSVFIFPPSDEQLKKSGTASVVCLLNNFYPRREEAKVQWKVDNALQSGNSQESVTEEQDSKDSTYSLSSTLTLSKADYEKHKVYACCEVTHQGLSSPVTKSFNRGEC
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.629
-
Maximal score value
-
2.5786
-
Average score
-
-0.7355
-
Total score value
-
-157.3923
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
A |
-2.3357 |
|
2 |
I |
A |
0.0000 |
|
3 |
Q |
A |
-1.9086 |
|
4 |
M |
A |
0.0000 |
|
5 |
T |
A |
-0.9293 |
|
6 |
Q |
A |
0.0000 |
|
7 |
S |
A |
0.2624 |
|
8 |
P |
A |
0.8940 |
|
9 |
I |
A |
1.9446 |
|
10 |
L |
A |
1.1667 |
|
11 |
L |
A |
0.4061 |
|
12 |
S |
A |
-0.4441 |
|
13 |
A |
A |
0.0000 |
|
14 |
S |
A |
-0.8859 |
|
15 |
V |
A |
-0.1286 |
|
16 |
G |
A |
-0.8346 |
|
17 |
D |
A |
-1.8646 |
|
18 |
R |
A |
-2.3641 |
|
19 |
V |
A |
0.0000 |
|
20 |
T |
A |
-0.5962 |
|
21 |
I |
A |
0.0000 |
|
22 |
T |
A |
-0.6179 |
|
23 |
C |
A |
0.0000 |
|
24 |
R |
A |
-2.9666 |
|
25 |
A |
A |
0.0000 |
|
26 |
S |
A |
-2.3563 |
|
27 |
Q |
A |
-3.0932 |
|
28 |
D |
A |
-2.8909 |
|
29 |
V |
A |
0.0000 |
|
30 |
N |
A |
-1.6528 |
|
31 |
T |
A |
-0.8540 |
|
32 |
A |
A |
-0.3869 |
|
33 |
V |
A |
0.0000 |
|
34 |
A |
A |
0.9310 |
|
35 |
W |
A |
0.0000 |
|
36 |
Y |
A |
-0.1024 |
|
37 |
Q |
A |
0.0000 |
|
38 |
Q |
A |
-1.5222 |
|
39 |
R |
A |
-1.8982 |
|
40 |
T |
A |
-1.6169 |
|
41 |
N |
A |
-1.6208 |
|
42 |
G |
A |
-1.4669 |
|
43 |
S |
A |
-1.1868 |
|
44 |
P |
A |
-1.3447 |
|
45 |
R |
A |
-1.5247 |
|
46 |
L |
A |
0.0045 |
|
47 |
L |
A |
0.0000 |
|
48 |
I |
A |
0.0000 |
|
49 |
Y |
A |
1.8385 |
|
50 |
S |
A |
0.5896 |
|
51 |
A |
A |
0.0000 |
|
52 |
S |
A |
0.9009 |
|
53 |
F |
A |
2.5786 |
|
54 |
L |
A |
2.0275 |
|
55 |
Y |
A |
1.6530 |
|
56 |
S |
A |
0.4951 |
|
57 |
G |
A |
-0.1615 |
|
58 |
V |
A |
0.0250 |
|
59 |
P |
A |
-0.1794 |
|
60 |
S |
A |
-0.3113 |
|
61 |
R |
A |
-0.7717 |
|
62 |
F |
A |
0.0000 |
|
63 |
S |
A |
0.0795 |
|
64 |
G |
A |
0.1026 |
|
65 |
S |
A |
-0.7771 |
|
66 |
R |
A |
-2.0126 |
|
67 |
S |
A |
-1.6349 |
|
68 |
G |
A |
-2.0553 |
|
69 |
T |
A |
-2.5416 |
|
70 |
D |
A |
-2.6054 |
|
71 |
F |
A |
0.0000 |
|
72 |
T |
A |
-0.9202 |
|
73 |
L |
A |
0.0000 |
|
74 |
T |
A |
-0.6362 |
|
75 |
I |
A |
0.0000 |
|
76 |
S |
A |
-1.5453 |
|
77 |
S |
A |
-1.2380 |
|
78 |
L |
A |
0.0000 |
|
79 |
Q |
A |
-0.9032 |
|
80 |
P |
A |
-1.6157 |
|
81 |
E |
A |
-1.9593 |
|
82 |
D |
A |
0.0000 |
|
83 |
E |
A |
0.0000 |
|
84 |
A |
A |
0.0000 |
|
85 |
D |
A |
-1.0064 |
|
86 |
Y |
A |
0.0000 |
|
87 |
Y |
A |
0.1317 |
|
88 |
C |
A |
0.0000 |
|
89 |
Q |
A |
0.0000 |
|
90 |
Q |
A |
0.0000 |
|
91 |
H |
A |
-0.4159 |
|
92 |
Y |
A |
0.2288 |
|
93 |
T |
A |
-0.3870 |
|
94 |
T |
A |
-0.5496 |
|
95 |
P |
A |
-0.5720 |
|
96 |
P |
A |
-0.4621 |
|
97 |
T |
A |
-0.0108 |
|
98 |
F |
A |
1.2529 |
|
99 |
G |
A |
0.0000 |
|
100 |
A |
A |
0.4419 |
|
101 |
G |
A |
0.3776 |
|
102 |
T |
A |
0.0000 |
|
103 |
K |
A |
-0.8550 |
|
104 |
V |
A |
0.0000 |
|
105 |
E |
A |
-1.2447 |
|
106 |
I |
A |
0.0000 |
|
107 |
K |
A |
-1.4070 |
|
108 |
R |
A |
-0.9096 |
|
109 |
T |
A |
-0.2072 |
|
110 |
V |
A |
0.0859 |
|
111 |
A |
A |
-0.0682 |
|
112 |
A |
A |
-0.2846 |
|
113 |
P |
A |
0.0000 |
|
114 |
S |
A |
-0.1496 |
|
115 |
V |
A |
0.0000 |
|
116 |
F |
A |
1.1847 |
|
117 |
I |
A |
1.1842 |
|
118 |
F |
A |
1.4037 |
|
119 |
P |
A |
-0.2206 |
|
120 |
P |
A |
0.0000 |
|
121 |
S |
A |
-1.7906 |
|
122 |
D |
A |
-3.2182 |
|
123 |
E |
A |
-3.3941 |
|
124 |
Q |
A |
-2.4947 |
|
125 |
L |
A |
-2.5799 |
|
126 |
K |
A |
-3.0451 |
|
127 |
S |
A |
-1.9494 |
|
128 |
G |
A |
-1.3363 |
|
129 |
T |
A |
-0.9948 |
|
130 |
A |
A |
0.0000 |
|
131 |
S |
A |
0.0386 |
|
132 |
V |
A |
0.0000 |
|
133 |
V |
A |
0.7497 |
|
134 |
C |
A |
0.0000 |
|
135 |
L |
A |
0.4796 |
|
136 |
L |
A |
0.0000 |
|
137 |
N |
A |
-0.6890 |
|
138 |
N |
A |
-1.5532 |
|
139 |
F |
A |
0.0000 |
|
140 |
Y |
A |
-1.3313 |
|
141 |
P |
A |
-1.8308 |
|
142 |
R |
A |
-3.1503 |
|
143 |
E |
A |
-3.1990 |
|
144 |
A |
A |
-2.3067 |
|
145 |
K |
A |
-2.3145 |
|
146 |
V |
A |
0.0000 |
|
147 |
Q |
A |
-0.7220 |
|
148 |
W |
A |
0.0000 |
|
149 |
K |
A |
-0.6490 |
|
150 |
V |
A |
0.0000 |
|
151 |
D |
A |
-1.9469 |
|
152 |
N |
A |
-1.5415 |
|
153 |
A |
A |
-0.2605 |
|
154 |
L |
A |
0.7270 |
|
155 |
Q |
A |
-0.4179 |
|
156 |
S |
A |
-0.6936 |
|
157 |
G |
A |
-1.4505 |
|
158 |
N |
A |
-1.8974 |
|
159 |
S |
A |
-1.8057 |
|
160 |
Q |
A |
-2.2690 |
|
161 |
E |
A |
-1.9188 |
|
162 |
S |
A |
-1.1540 |
|
163 |
V |
A |
-0.7972 |
|
164 |
T |
A |
-1.3430 |
|
165 |
E |
A |
-2.3439 |
|
166 |
Q |
A |
0.0000 |
|
167 |
D |
A |
-2.4827 |
|
168 |
S |
A |
-2.3367 |
|
169 |
K |
A |
-2.6817 |
|
170 |
D |
A |
-2.1301 |
|
171 |
S |
A |
0.0000 |
|
172 |
T |
A |
0.0000 |
|
173 |
Y |
A |
0.0000 |
|
174 |
S |
A |
-1.1304 |
|
175 |
L |
A |
0.0000 |
|
176 |
S |
A |
-0.3618 |
|
177 |
S |
A |
0.0000 |
|
178 |
T |
A |
-0.6567 |
|
179 |
L |
A |
0.0000 |
|
180 |
T |
A |
-0.7765 |
|
181 |
L |
A |
-0.8877 |
|
182 |
S |
A |
-1.2898 |
|
183 |
K |
A |
-2.1630 |
|
184 |
A |
A |
-1.9168 |
|
185 |
D |
A |
-2.5364 |
|
186 |
Y |
A |
0.0000 |
|
187 |
E |
A |
-3.5582 |
|
188 |
K |
A |
-3.6290 |
|
189 |
H |
A |
-2.9134 |
|
190 |
K |
A |
-3.3245 |
|
191 |
V |
A |
-1.6037 |
|
192 |
Y |
A |
0.0000 |
|
193 |
A |
A |
0.0000 |
|
194 |
C |
A |
0.0000 |
|
195 |
E |
A |
-0.9626 |
|
196 |
V |
A |
0.0000 |
|
197 |
T |
A |
-1.1972 |
|
198 |
H |
A |
0.0000 |
|
199 |
Q |
A |
-1.7783 |
|
200 |
G |
A |
-0.4854 |
|
201 |
L |
A |
-0.2455 |
|
202 |
S |
A |
-0.4359 |
|
203 |
S |
A |
-0.4216 |
|
204 |
P |
A |
-0.6013 |
|
205 |
V |
A |
0.0184 |
|
206 |
T |
A |
-0.4141 |
|
207 |
K |
A |
-0.4306 |
|
208 |
S |
A |
-0.4075 |
|
209 |
F |
A |
0.0000 |
|
210 |
N |
A |
-2.1017 |
|
211 |
R |
A |
-2.5928 |
|
212 |
G |
A |
-2.0767 |
|
213 |
E |
A |
-2.2378 |
|
214 |
C |
A |
-0.4268 |
|