Project name: test

Chain sequence(s)	H: QVQLLETGGGLVKPGQSLKLSCAASGFTFTSYAMHWVRQPPGKGLEWVAVVSYDGNYKYYADSVQGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDSRLRSLLYFEWLSQGYFNPWGQGTTLTVSS; L: DIQMTQSPSSLSASVGDRVTITCRSSQSITFWYKNYLAWYQQKPGKAPKLLIYWGSYLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQHYRTPPSFGQGTKVEIKG
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.0174
• Maximal score value: 1.72
• Average score: -0.2141
• Total score value: -51.6091

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.0466
2	V	H	0.3816
3	Q	H	-0.4861
4	L	H	0.0000
5	L	H	1.1773
6	E	H	-0.0032
7	T	H	-0.1496
8	G	H	-0.2595
9	G	H	-0.2830
11	G	H	0.1096
12	L	H	1.5184
13	V	H	0.0000
14	K	H	-1.7425
15	P	H	-0.4927
16	G	H	-0.6971
17	Q	H	-1.1500
18	S	H	-0.3078
19	L	H	0.1078
20	K	H	-1.1180
21	L	H	0.0000
22	S	H	0.0000
23	C	H	0.0000
24	A	H	0.0245
25	A	H	0.0000
26	S	H	-0.1674
27	G	H	-0.2892
28	F	H	0.2418
29	T	H	-0.0064
30	F	H	0.0000
35	T	H	-0.0311
36	S	H	0.0000
37	Y	H	0.1662
38	A	H	0.0000
39	M	H	0.0000
40	H	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	R	H	0.0000
44	Q	H	-0.1460
45	P	H	-0.1027
46	P	H	-0.3476
47	G	H	-0.8335
48	K	H	-1.8179
49	G	H	-0.4792
50	L	H	0.0000
51	E	H	-0.5519
52	W	H	0.0000
53	V	H	0.0000
54	A	H	0.0000
55	V	H	0.0000
56	V	H	0.0000
57	S	H	0.0000
58	Y	H	0.0619
59	D	H	-1.2057
62	G	H	-0.5710
63	N	H	-1.2311
64	Y	H	-0.0356
65	K	H	-0.4501
66	Y	H	0.1571
67	Y	H	0.1928
68	A	H	-0.3002
69	D	H	-1.8122
70	S	H	-0.4649
71	V	H	0.0000
72	Q	H	-1.2851
74	G	H	-0.7478
75	R	H	-0.4606
76	F	H	0.0000
77	T	H	-0.0808
78	I	H	0.0000
79	S	H	-0.1384
80	R	H	-0.3591
81	D	H	-0.7786
82	N	H	-0.6975
83	S	H	-0.6118
84	K	H	-1.8643
85	N	H	-1.0401
86	T	H	0.0000
87	L	H	0.0000
88	Y	H	0.2382
89	L	H	0.0000
90	Q	H	-0.5687
91	M	H	0.0000
92	N	H	-0.6605
93	S	H	-0.3227
94	L	H	0.0000
95	R	H	-1.2497
96	A	H	-0.5127
97	E	H	-1.8091
98	D	H	0.0000
99	T	H	-0.0130
100	A	H	0.0000
101	V	H	0.3921
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	K	H	0.0000
107	D	H	0.0000
108	S	H	-0.3576
109	R	H	-1.5085
110	L	H	0.7726
111	R	H	-1.5773
111A	S	H	-0.2312
111B	L	H	0.7766
111C	L	H	0.0000
111D	Y	H	1.5400
111V	F	H	1.2215
111W	E	H	-0.8313
111X	W	H	0.4599
111Y	L	H	0.3574
111Z	S	H	-0.1436
112	Q	H	0.0000
113	G	H	0.0000
114	Y	H	0.0000
115	F	H	0.0000
116	N	H	-0.3244
117	P	H	-0.0790
118	W	H	0.1429
119	G	H	-0.2361
120	Q	H	-1.2157
121	G	H	-0.2725
122	T	H	-0.0257
123	T	H	-0.0153
124	L	H	0.0000
125	T	H	0.1698
126	V	H	0.0000
127	S	H	-0.1548
128	S	H	-0.4497
1	D	L	-1.7894
2	I	L	0.0000
3	Q	L	-1.1983
4	M	L	0.0000
5	T	L	-0.0529
6	Q	L	0.0000
7	S	L	-0.1829
8	P	L	-0.1841
9	S	L	-0.2707
10	S	L	-0.3343
11	L	L	0.1642
12	S	L	-0.2644
13	A	L	0.0000
14	S	L	-0.1210
15	V	L	0.9230
16	G	L	-0.1173
17	D	L	-1.2282
18	R	L	-2.0174
19	V	L	0.0000
20	T	L	-0.0642
21	I	L	0.0000
22	T	L	-0.0198
23	C	L	0.0000
24	R	L	-1.9483
25	S	L	0.0000
26	S	L	-0.3088
27	Q	L	-0.6358
28	S	L	-0.2487
29	I	L	0.0000
30	T	L	0.2269
31	F	L	1.7200
34	W	L	1.7133
35	Y	L	1.4057
36	K	L	-0.5028
37	N	L	-0.3508
38	Y	L	0.1427
39	L	L	0.0000
40	A	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	0.0000
45	K	L	-0.3673
46	P	L	-0.4017
47	G	L	-0.8334
48	K	L	-1.7858
49	A	L	-0.3080
50	P	L	0.0000
51	K	L	-1.4846
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	0.0000
56	W	L	0.4828
57	G	L	0.0000
65	S	L	0.0913
66	Y	L	1.3755
67	L	L	0.6823
68	E	L	-0.2380
69	S	L	-0.3554
70	G	L	-0.4536
71	V	L	0.1483
72	P	L	-0.2404
74	S	L	-0.3990
75	R	L	-0.8068
76	F	L	0.0000
77	S	L	-0.1517
78	G	L	0.0000
79	S	L	-0.2481
80	G	L	-0.2694
83	S	L	-0.2632
84	G	L	-0.1424
85	T	L	-0.2241
86	D	L	-1.1052
87	F	L	0.0000
88	T	L	-0.0252
89	L	L	0.0000
90	T	L	-0.0246
91	I	L	0.0000
92	S	L	-0.4145
93	S	L	-0.0967
94	L	L	0.0000
95	Q	L	-0.3375
96	P	L	-0.6439
97	E	L	-1.8667
98	D	L	0.0000
99	F	L	0.5035
100	A	L	0.0000
101	T	L	-0.1646
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	Q	L	0.0000
107	H	L	0.0000
108	Y	L	-0.0006
109	R	L	-0.8557
114	T	L	0.0000
115	P	L	-0.0391
116	P	L	0.0000
117	S	L	0.0197
118	F	L	0.2632
119	G	L	0.0000
120	Q	L	-1.2077
121	G	L	-0.2741
122	T	L	0.0000
123	K	L	-1.0958
124	V	L	0.0000
125	E	L	-1.1154
126	I	L	0.0656
127	K	L	-1.6796
128	G	L	-0.7842