| Chain sequence(s) |
A: ETCPIFYDVFFAVANGNELLLDLSLTKVNATEPERTAMKKIQDCYVENGLISRVLDGLVMTTISSSKDCEICPAVKRDVDLFLTGTPDEYVEQVAQYKALPVVLENARILKNCVDAKMTEEDKENALSLLDKIYTSPLCLE B: ETCPIFYDVFFAVANGNELLLDLSLTKVNATEPERTAMKKIQDCYVENGLISRVLDGLVMTTISSSKDCMEICPAVKRDVDLFLTGTPDEYVEQVAQYKALPVVLENARILKNCVDAKMTEEDKENALSLLDKIYTSPLCLE |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 5 | E | A | -2.0997 | |
| 6 | T | A | -1.2800 | |
| 7 | C | A | 0.0000 | |
| 8 | P | A | -1.1104 | |
| 9 | I | A | 0.0000 | |
| 10 | F | A | 0.0000 | |
| 11 | Y | A | -0.2498 | |
| 12 | D | A | -0.6025 | |
| 13 | V | A | 0.0000 | |
| 14 | F | A | 0.4528 | |
| 15 | F | A | 1.1617 | |
| 16 | A | A | 0.0000 | |
| 17 | V | A | 0.0000 | |
| 18 | A | A | 0.0000 | |
| 19 | N | A | -0.4169 | |
| 20 | G | A | -0.6968 | |
| 21 | N | A | -0.8285 | |
| 22 | E | A | -1.4350 | |
| 23 | L | A | 1.0738 | |
| 24 | L | A | 1.0888 | |
| 25 | L | A | 0.0000 | |
| 26 | D | A | -0.1221 | |
| 27 | L | A | 0.7250 | |
| 28 | S | A | 0.0000 | |
| 29 | L | A | 0.0000 | |
| 30 | T | A | -1.1604 | |
| 31 | K | A | -1.8799 | |
| 32 | V | A | 0.0000 | |
| 33 | N | A | -2.1149 | |
| 34 | A | A | -1.6848 | |
| 35 | T | A | -1.4247 | |
| 36 | E | A | -2.2172 | |
| 37 | P | A | -1.8215 | |
| 38 | E | A | 0.0000 | |
| 39 | R | A | -1.5994 | |
| 40 | T | A | -1.3077 | |
| 41 | A | A | 0.0000 | |
| 42 | M | A | 0.0000 | |
| 43 | K | A | -1.7325 | |
| 44 | K | A | -0.9544 | |
| 45 | I | A | 0.0000 | |
| 46 | Q | A | 0.0000 | |
| 47 | D | A | -1.7061 | |
| 48 | C | A | 0.0000 | |
| 49 | Y | A | 0.0000 | |
| 50 | V | A | 0.1178 | |
| 51 | E | A | -1.3653 | |
| 52 | N | A | -0.3377 | |
| 53 | G | A | 0.9155 | |
| 54 | L | A | 2.5663 | |
| 55 | I | A | 3.2036 | |
| 56 | S | A | 0.0000 | |
| 57 | R | A | 1.6959 | |
| 58 | V | A | 2.6561 | |
| 59 | L | A | 2.0801 | |
| 60 | D | A | 0.0000 | |
| 61 | G | A | 1.1334 | |
| 62 | L | A | 0.8866 | |
| 63 | V | A | 0.0000 | |
| 64 | M | A | 0.0000 | |
| 65 | T | A | 0.0373 | |
| 66 | T | A | -0.1696 | |
| 67 | I | A | 0.0000 | |
| 68 | S | A | -0.6016 | |
| 69 | S | A | -0.8219 | |
| 70 | S | A | -1.3312 | |
| 71 | K | A | -2.4828 | |
| 72 | D | A | -2.4640 | |
| 73 | C | A | -1.0763 | |
| 93 | E | A | -1.8671 | |
| 94 | I | A | 0.0000 | |
| 95 | C | A | 0.0000 | |
| 96 | P | A | -1.4795 | |
| 97 | A | A | -1.4157 | |
| 98 | V | A | 0.0000 | |
| 99 | K | A | -2.2888 | |
| 100 | R | A | -2.6761 | |
| 101 | D | A | 0.0000 | |
| 102 | V | A | -1.2127 | |
| 103 | D | A | -1.8159 | |
| 104 | L | A | 0.0000 | |
| 105 | F | A | 0.0000 | |
| 106 | L | A | 0.0000 | |
| 107 | T | A | -1.0654 | |
| 108 | G | A | -1.3251 | |
| 109 | T | A | -1.4794 | |
| 110 | P | A | -2.1897 | |
| 111 | D | A | -3.3337 | |
| 112 | E | A | -3.0506 | |
| 113 | Y | A | 0.0000 | |
| 114 | V | A | 0.0000 | |
| 115 | E | A | -3.2989 | |
| 116 | Q | A | -2.2552 | |
| 117 | V | A | 0.0000 | |
| 118 | A | A | -1.0681 | |
| 119 | Q | A | -1.5972 | |
| 120 | Y | A | -0.5730 | |
| 121 | K | A | -0.4309 | |
| 122 | A | A | -0.1200 | |
| 123 | L | A | 1.0960 | |
| 124 | P | A | 0.5131 | |
| 125 | V | A | 0.9784 | |
| 126 | V | A | 0.0000 | |
| 127 | L | A | -0.6433 | |
| 128 | E | A | -1.5464 | |
| 129 | N | A | 0.0000 | |
| 130 | A | A | 0.0000 | |
| 131 | R | A | -2.2924 | |
| 132 | I | A | -1.0953 | |
| 133 | L | A | 0.0000 | |
| 134 | K | A | 0.0000 | |
| 135 | N | A | 0.0000 | |
| 136 | C | A | -0.8285 | |
| 137 | V | A | 0.0000 | |
| 138 | D | A | -0.8935 | |
| 139 | A | A | -0.5464 | |
| 140 | K | A | -1.0379 | |
| 141 | M | A | 0.0000 | |
| 142 | T | A | -2.2625 | |
| 143 | E | A | -3.3949 | |
| 144 | E | A | -3.4991 | |
| 145 | D | A | 0.0000 | |
| 146 | K | A | -2.4507 | |
| 147 | E | A | -3.0688 | |
| 148 | N | A | -2.3598 | |
| 149 | A | A | 0.0000 | |
| 150 | L | A | -1.1133 | |
| 151 | S | A | -1.2182 | |
| 152 | L | A | 0.0000 | |
| 153 | L | A | 0.0000 | |
| 154 | D | A | -2.0690 | |
| 155 | K | A | -1.7277 | |
| 156 | I | A | 0.0000 | |
| 157 | Y | A | 0.0000 | |
| 158 | T | A | -0.8370 | |
| 159 | S | A | 0.0000 | |
| 160 | P | A | -0.3774 | |
| 161 | L | A | -0.0143 | |
| 162 | C | A | 0.0000 | |
| 163 | L | A | -0.4071 | |
| 164 | E | A | -1.5755 | |
| 5 | E | B | -2.0420 | |
| 6 | T | B | -1.4462 | |
| 7 | C | B | 0.0000 | |
| 8 | P | B | -1.3089 | |
| 9 | I | B | 0.0000 | |
| 10 | F | B | 0.0000 | |
| 11 | Y | B | -0.3251 | |
| 12 | D | B | -0.7072 | |
| 13 | V | B | 0.0000 | |
| 14 | F | B | 0.4157 | |
| 15 | F | B | 1.0926 | |
| 16 | A | B | 0.0000 | |
| 17 | V | B | 0.0000 | |
| 18 | A | B | 0.0000 | |
| 19 | N | B | -0.4938 | |
| 20 | G | B | -0.8050 | |
| 21 | N | B | -0.9239 | |
| 22 | E | B | -1.4055 | |
| 23 | L | B | 1.1379 | |
| 24 | L | B | 1.1197 | |
| 25 | L | B | 0.0000 | |
| 26 | D | B | 0.2282 | |
| 27 | L | B | 1.3888 | |
| 28 | S | B | 0.0000 | |
| 29 | L | B | 0.0000 | |
| 30 | T | B | -0.3165 | |
| 31 | K | B | -0.6138 | |
| 32 | V | B | 0.0000 | |
| 33 | N | B | -1.4901 | |
| 34 | A | B | -1.1687 | |
| 35 | T | B | -1.2788 | |
| 36 | E | B | -2.1654 | |
| 37 | P | B | -1.8624 | |
| 38 | E | B | 0.0000 | |
| 39 | R | B | -1.5330 | |
| 40 | T | B | -1.1291 | |
| 41 | A | B | 0.0000 | |
| 42 | M | B | 0.0000 | |
| 43 | K | B | -1.7235 | |
| 44 | K | B | -1.3061 | |
| 45 | I | B | 0.0000 | |
| 46 | Q | B | 0.0000 | |
| 47 | D | B | -2.0840 | |
| 48 | C | B | 0.0000 | |
| 49 | Y | B | 0.0000 | |
| 50 | V | B | -0.2149 | |
| 51 | E | B | -1.5131 | |
| 52 | N | B | -0.2761 | |
| 53 | G | B | 0.8844 | |
| 54 | L | B | 2.5406 | |
| 55 | I | B | 3.2239 | |
| 56 | S | B | 0.0000 | |
| 57 | R | B | 1.6228 | |
| 58 | V | B | 2.7082 | |
| 59 | L | B | 1.9683 | |
| 60 | D | B | 0.0000 | |
| 61 | G | B | 1.0942 | |
| 62 | L | B | 0.8139 | |
| 63 | V | B | 0.0000 | |
| 64 | M | B | 0.0000 | |
| 65 | T | B | 0.0241 | |
| 66 | T | B | -0.2136 | |
| 67 | I | B | 0.0000 | |
| 68 | S | B | -0.5757 | |
| 69 | S | B | -0.7196 | |
| 70 | S | B | -1.2389 | |
| 71 | K | B | -2.2781 | |
| 72 | D | B | -2.3072 | |
| 73 | C | B | -0.9242 | |
| 74 | M | B | -0.0282 | |
| 93 | E | B | -2.0324 | |
| 94 | I | B | 0.0000 | |
| 95 | C | B | 0.0000 | |
| 96 | P | B | -1.5903 | |
| 97 | A | B | -1.5059 | |
| 98 | V | B | 0.0000 | |
| 99 | K | B | -2.3141 | |
| 100 | R | B | -2.6221 | |
| 101 | D | B | 0.0000 | |
| 102 | V | B | -1.1374 | |
| 103 | D | B | -1.6582 | |
| 104 | L | B | -1.6491 | |
| 105 | F | B | 0.0000 | |
| 106 | L | B | 0.0000 | |
| 107 | T | B | -1.0686 | |
| 108 | G | B | -1.3064 | |
| 109 | T | B | -1.6909 | |
| 110 | P | B | -2.4061 | |
| 111 | D | B | -3.3366 | |
| 112 | E | B | -3.0194 | |
| 113 | Y | B | 0.0000 | |
| 114 | V | B | 0.0000 | |
| 115 | E | B | -3.2449 | |
| 116 | Q | B | 0.0000 | |
| 117 | V | B | 0.0000 | |
| 118 | A | B | -0.9395 | |
| 119 | Q | B | -1.5552 | |
| 120 | Y | B | -0.4877 | |
| 121 | K | B | -0.1562 | |
| 122 | A | B | 0.0858 | |
| 123 | L | B | 1.4727 | |
| 124 | P | B | 0.5051 | |
| 125 | V | B | 0.6192 | |
| 126 | V | B | 0.0000 | |
| 127 | L | B | -0.6051 | |
| 128 | E | B | -1.4385 | |
| 129 | N | B | 0.0000 | |
| 130 | A | B | 0.0000 | |
| 131 | R | B | -2.2628 | |
| 132 | I | B | -0.6569 | |
| 133 | L | B | 0.0000 | |
| 134 | K | B | 0.0000 | |
| 135 | N | B | -1.7950 | |
| 136 | C | B | -1.5288 | |
| 137 | V | B | 0.0000 | |
| 138 | D | B | -2.0124 | |
| 139 | A | B | -1.2687 | |
| 140 | K | B | -1.8588 | |
| 141 | M | B | 0.0000 | |
| 142 | T | B | -2.3431 | |
| 143 | E | B | -3.5457 | |
| 144 | E | B | -3.5072 | |
| 145 | D | B | 0.0000 | |
| 146 | K | B | -2.7440 | |
| 147 | E | B | -3.0747 | |
| 148 | N | B | -2.3668 | |
| 149 | A | B | 0.0000 | |
| 150 | L | B | -1.0819 | |
| 151 | S | B | -1.2217 | |
| 152 | L | B | 0.0000 | |
| 153 | L | B | 0.0000 | |
| 154 | D | B | -2.0653 | |
| 155 | K | B | -1.4949 | |
| 156 | I | B | 0.0000 | |
| 157 | Y | B | -1.0513 | |
| 158 | T | B | -0.9130 | |
| 159 | S | B | 0.0000 | |
| 160 | P | B | -0.6551 | |
| 161 | L | B | -0.3812 | |
| 162 | C | B | 0.0000 | |
| 163 | L | B | -0.7601 | |
| 164 | E | B | -1.7268 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine