Chain sequence(s) |
H: QLQESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDVWGQGTLVTVSS L: DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLESGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIK |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
1 | D | L | -2.2743 | |
2 | I | L | 0.0000 | |
3 | Q | L | -2.2064 | |
4 | M | L | 0.0000 | |
5 | T | L | -1.3994 | |
6 | Q | L | 0.0000 | |
7 | S | L | -0.7740 | |
8 | P | L | -0.5358 | |
9 | S | L | -0.7168 | |
10 | S | L | -0.7256 | |
11 | L | L | -0.6134 | |
12 | S | L | -1.0178 | |
13 | A | L | 0.0000 | |
14 | S | L | -0.9929 | |
15 | V | L | -0.2740 | |
16 | G | L | -0.9799 | |
17 | D | L | -1.8880 | |
18 | R | L | -2.4173 | |
19 | V | L | 0.0000 | |
20 | T | L | -0.6615 | |
21 | I | L | 0.0000 | |
22 | T | L | -0.9076 | |
23 | C | L | 0.0000 | |
24 | R | L | -2.9820 | |
25 | A | L | 0.0000 | |
26 | S | L | -2.3211 | |
27 | Q | L | -2.8691 | |
28 | D | L | -2.8116 | |
29 | V | L | 0.0000 | |
30 | N | L | -1.7121 | |
31 | T | L | -0.8417 | |
32 | A | L | -0.0185 | |
33 | V | L | 0.0000 | |
34 | A | L | 0.0000 | |
35 | W | L | 0.0000 | |
36 | Y | L | 0.0000 | |
37 | Q | L | 0.0000 | |
38 | Q | L | -1.2363 | |
39 | K | L | -1.5773 | |
40 | P | L | -1.1391 | |
41 | G | L | -1.6762 | |
42 | K | L | -2.6366 | |
43 | A | L | -1.7483 | |
44 | P | L | 0.0000 | |
45 | K | L | -1.8519 | |
46 | L | L | 0.0000 | |
47 | L | L | 0.0000 | |
48 | I | L | 0.0000 | |
49 | Y | L | 0.9029 | |
50 | S | L | 0.4059 | |
51 | A | L | 0.0000 | |
52 | S | L | 0.0840 | |
53 | F | L | 1.2678 | |
54 | L | L | 0.6300 | |
55 | E | L | -0.2154 | |
56 | S | L | -0.3632 | |
57 | G | L | -0.5768 | |
58 | V | L | -0.4530 | |
59 | P | L | -0.3909 | |
60 | S | L | -0.4583 | |
61 | R | L | -0.6733 | |
62 | F | L | 0.0000 | |
63 | S | L | -0.0369 | |
64 | G | L | -0.3241 | |
65 | S | L | -1.2270 | |
66 | R | L | -2.6574 | |
67 | S | L | -1.8439 | |
68 | G | L | -2.0690 | |
69 | T | L | -2.4273 | |
70 | D | L | -2.3791 | |
71 | F | L | 0.0000 | |
72 | T | L | -1.0413 | |
73 | L | L | 0.0000 | |
74 | T | L | -0.6161 | |
75 | I | L | 0.0000 | |
76 | S | L | -1.2873 | |
77 | S | L | -1.1760 | |
78 | L | L | 0.0000 | |
79 | Q | L | -0.7582 | |
80 | P | L | -1.1714 | |
81 | E | L | -1.8497 | |
82 | D | L | 0.0000 | |
83 | F | L | -0.6353 | |
84 | A | L | 0.0000 | |
85 | T | L | -0.6583 | |
86 | Y | L | 0.0000 | |
87 | Y | L | 0.0000 | |
88 | C | L | 0.0000 | |
89 | Q | L | 0.0000 | |
90 | Q | L | 0.0000 | |
91 | H | L | 0.0000 | |
92 | Y | L | 0.5632 | |
93 | T | L | 0.2020 | |
94 | T | L | -0.3984 | |
95 | P | L | -0.8183 | |
96 | P | L | 0.0000 | |
97 | T | L | -0.7113 | |
98 | F | L | -0.5714 | |
99 | G | L | 0.0000 | |
100 | Q | L | -1.6910 | |
101 | G | L | 0.0000 | |
102 | T | L | 0.0000 | |
103 | K | L | -0.9370 | |
104 | V | L | 0.0000 | |
105 | E | L | -1.7467 | |
106 | I | L | -1.0224 | |
107 | K | L | -1.6007 | |
3 | Q | H | -1.6742 | |
4 | L | H | 0.0000 | |
5 | Q | H | -1.8006 | |
6 | E | H | 0.0000 | |
7 | S | H | -0.8731 | |
8 | G | H | -0.7890 | |
9 | G | H | 0.0495 | |
10 | G | H | 0.6824 | |
11 | L | H | 1.3990 | |
12 | V | H | -0.0069 | |
13 | Q | H | -1.2383 | |
14 | P | H | -1.4771 | |
15 | G | H | -1.3573 | |
16 | G | H | -1.1108 | |
17 | S | H | -1.1446 | |
18 | L | H | -1.0266 | |
19 | R | H | -2.0366 | |
20 | L | H | 0.0000 | |
21 | S | H | -0.7809 | |
22 | C | H | 0.0000 | |
23 | A | H | -1.1289 | |
24 | A | H | 0.0000 | |
25 | S | H | -1.2083 | |
26 | G | H | -0.9938 | |
27 | F | H | -1.2423 | |
28 | N | H | -2.3188 | |
29 | I | H | 0.0000 | |
30 | K | H | -2.7798 | |
31 | D | H | -3.0297 | |
32 | T | H | 0.0000 | |
33 | Y | H | -0.7601 | |
34 | I | H | 0.0000 | |
35 | H | H | 0.0000 | |
36 | W | H | 0.0000 | |
37 | V | H | 0.0000 | |
38 | R | H | 0.0000 | |
39 | Q | H | -0.7675 | |
40 | A | H | -1.1459 | |
41 | P | H | -0.8274 | |
42 | G | H | -1.4745 | |
43 | K | H | -2.4342 | |
44 | G | H | -1.7452 | |
45 | L | H | 0.0000 | |
46 | E | H | -1.4003 | |
47 | W | H | 0.0000 | |
48 | V | H | 0.0000 | |
49 | A | H | 0.0000 | |
50 | R | H | -0.5983 | |
51 | I | H | 0.0000 | |
52 | Y | H | -0.4841 | |
52A | P | H | 0.0000 | |
53 | T | H | -1.2303 | |
54 | N | H | -0.9888 | |
55 | G | H | -0.3462 | |
56 | Y | H | 0.5358 | |
57 | T | H | -0.3602 | |
58 | R | H | -1.7900 | |
59 | Y | H | -1.8420 | |
60 | A | H | -1.9043 | |
61 | D | H | -2.7025 | |
62 | S | H | -1.8312 | |
63 | V | H | 0.0000 | |
64 | K | H | -2.8950 | |
65 | G | H | -1.8105 | |
66 | R | H | -1.6128 | |
67 | F | H | 0.0000 | |
68 | T | H | -1.0465 | |
69 | I | H | 0.0000 | |
70 | S | H | -0.0876 | |
71 | A | H | -0.7111 | |
72 | D | H | -1.2700 | |
73 | T | H | -1.5704 | |
74 | S | H | -1.5540 | |
75 | K | H | -2.1717 | |
76 | N | H | -1.7288 | |
77 | T | H | -1.1519 | |
78 | A | H | 0.0000 | |
79 | Y | H | -0.4139 | |
80 | L | H | 0.0000 | |
81 | Q | H | -1.1125 | |
82 | M | H | 0.0000 | |
82A | N | H | -1.3622 | |
82B | S | H | -1.2185 | |
82C | L | H | 0.0000 | |
83 | R | H | -2.1211 | |
84 | A | H | -1.6142 | |
85 | E | H | -2.2065 | |
86 | D | H | 0.0000 | |
87 | T | H | -0.3819 | |
88 | A | H | 0.0000 | |
89 | V | H | 0.6848 | |
90 | Y | H | 0.0000 | |
91 | Y | H | 0.0000 | |
92 | C | H | 0.0000 | |
93 | S | H | 0.0000 | |
94 | R | H | -0.6186 | |
95 | W | H | -0.3187 | |
96 | G | H | 0.0000 | |
97 | G | H | -1.0050 | |
98 | D | H | -1.8103 | |
99 | G | H | 0.0000 | |
100 | F | H | 0.6778 | |
100A | Y | H | 0.6758 | |
100B | A | H | 0.0000 | |
100C | M | H | 0.0000 | |
101 | D | H | -0.3812 | |
102 | V | H | -0.5122 | |
103 | W | H | -0.8931 | |
104 | G | H | 0.0000 | |
105 | Q | H | -1.9816 | |
106 | G | H | 0.0000 | |
107 | T | H | 0.1416 | |
108 | L | H | 1.4562 | |
109 | V | H | 0.0000 | |
110 | T | H | 0.3004 | |
111 | V | H | 0.0000 | |
112 | S | H | -0.6267 | |
113 | S | H | -0.4858 |