Project name: 5njd:M
Status: done
submitted: 2019-03-21 13:07:10, status changed: 2019-03-21 13:18:14
Settings
Chain sequence(s)
|
M: SVLTQPPSVSGAPGQRVTISCSGSRSNIGSNTVKWYQQLPGTAPKLLIYYNDQRPSGVPDRFSGSKSGTSASLAITGLQAEDEADYYCQSYDRYTHPALLFGTGTKVTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.1934
-
Maximal score value
-
1.9968
-
Average score
-
-0.6893
-
Total score value
-
-146.8265
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
2 |
S |
M |
0.9308 |
|
3 |
V |
M |
1.9968 |
|
4 |
L |
M |
0.0000 |
|
5 |
T |
M |
0.2612 |
|
6 |
Q |
M |
0.0000 |
|
7 |
P |
M |
-0.4015 |
|
8 |
P |
M |
-0.5985 |
|
9 |
S |
M |
-0.5917 |
|
10 |
V |
M |
-0.1802 |
|
11 |
S |
M |
-0.3020 |
|
12 |
G |
M |
-0.6533 |
|
13 |
A |
M |
-0.7918 |
|
14 |
P |
M |
-1.3494 |
|
15 |
G |
M |
-1.8002 |
|
16 |
Q |
M |
-2.4663 |
|
17 |
R |
M |
-2.5443 |
|
18 |
V |
M |
-1.0489 |
|
19 |
T |
M |
-0.4075 |
|
20 |
I |
M |
0.0000 |
|
21 |
S |
M |
-0.3864 |
|
22 |
C |
M |
0.0000 |
|
23 |
S |
M |
-0.2834 |
|
24 |
G |
M |
-0.6090 |
|
25 |
S |
M |
-1.3396 |
|
26 |
R |
M |
-2.4588 |
|
27 |
S |
M |
-1.4562 |
|
28 |
N |
M |
0.0000 |
|
29 |
I |
M |
0.0000 |
|
30 |
G |
M |
-1.7569 |
|
31 |
S |
M |
-1.2787 |
|
32 |
N |
M |
-0.7134 |
|
33 |
T |
M |
-0.0697 |
|
34 |
V |
M |
0.0000 |
|
35 |
K |
M |
-0.1091 |
|
36 |
W |
M |
0.0000 |
|
37 |
Y |
M |
-0.1720 |
|
38 |
Q |
M |
0.0000 |
|
39 |
Q |
M |
-0.8456 |
|
40 |
L |
M |
-0.6837 |
|
41 |
P |
M |
-0.6685 |
|
42 |
G |
M |
-0.6261 |
|
43 |
T |
M |
-0.5564 |
|
44 |
A |
M |
-0.4888 |
|
45 |
P |
M |
-0.8396 |
|
46 |
K |
M |
-1.1718 |
|
47 |
L |
M |
-0.2846 |
|
48 |
L |
M |
0.0000 |
|
49 |
I |
M |
0.0000 |
|
50 |
Y |
M |
-0.0249 |
|
51 |
Y |
M |
0.3270 |
|
52 |
N |
M |
-1.0383 |
|
53 |
D |
M |
-2.1437 |
|
54 |
Q |
M |
-1.7612 |
|
55 |
R |
M |
-1.6496 |
|
56 |
P |
M |
-0.9444 |
|
57 |
S |
M |
-0.6550 |
|
58 |
G |
M |
-0.8350 |
|
59 |
V |
M |
-1.0279 |
|
60 |
P |
M |
-1.3306 |
|
61 |
D |
M |
-2.3222 |
|
62 |
R |
M |
-1.6763 |
|
63 |
F |
M |
0.0000 |
|
64 |
S |
M |
-1.4160 |
|
65 |
G |
M |
0.0000 |
|
66 |
S |
M |
-1.1307 |
|
67 |
K |
M |
-1.1524 |
|
68 |
S |
M |
-0.8518 |
|
69 |
G |
M |
-1.1766 |
|
70 |
T |
M |
-1.1955 |
|
71 |
S |
M |
-0.9064 |
|
72 |
A |
M |
0.0000 |
|
73 |
S |
M |
-0.6305 |
|
74 |
L |
M |
0.0000 |
|
75 |
A |
M |
-0.5450 |
|
76 |
I |
M |
0.0000 |
|
77 |
T |
M |
-1.6557 |
|
78 |
G |
M |
-1.6644 |
|
79 |
L |
M |
0.0000 |
|
80 |
Q |
M |
-2.0906 |
|
81 |
A |
M |
-1.5927 |
|
82 |
E |
M |
-2.2979 |
|
83 |
D |
M |
0.0000 |
|
84 |
E |
M |
0.0000 |
|
85 |
A |
M |
0.0000 |
|
86 |
D |
M |
-0.7709 |
|
87 |
Y |
M |
0.0000 |
|
88 |
Y |
M |
-0.0285 |
|
89 |
C |
M |
0.0000 |
|
90 |
Q |
M |
0.0000 |
|
91 |
S |
M |
0.0000 |
|
92 |
Y |
M |
0.2857 |
|
93 |
D |
M |
-1.0988 |
|
94 |
R |
M |
-1.9101 |
|
95 |
Y |
M |
-0.0171 |
|
96 |
T |
M |
-0.2939 |
|
97 |
H |
M |
-1.0521 |
|
98 |
P |
M |
-0.4200 |
|
99 |
A |
M |
0.3279 |
|
100 |
L |
M |
1.6018 |
|
101 |
L |
M |
0.0000 |
|
102 |
F |
M |
1.6391 |
|
103 |
G |
M |
0.9077 |
|
104 |
T |
M |
0.3800 |
|
105 |
G |
M |
-0.2903 |
|
106 |
T |
M |
0.0000 |
|
107 |
K |
M |
-1.0044 |
|
108 |
V |
M |
0.0000 |
|
109 |
T |
M |
-0.0214 |
|
110 |
V |
M |
0.0000 |
|
111 |
L |
M |
0.6197 |
|
112 |
G |
M |
-0.4414 |
|
113 |
Q |
M |
-0.7152 |
|
114 |
P |
M |
-1.1660 |
|
115 |
K |
M |
-2.2484 |
|
116 |
A |
M |
-1.4018 |
|
117 |
A |
M |
-0.8279 |
|
118 |
P |
M |
-0.5343 |
|
119 |
S |
M |
-0.3637 |
|
120 |
V |
M |
0.0000 |
|
121 |
T |
M |
0.2946 |
|
122 |
L |
M |
0.9532 |
|
123 |
F |
M |
1.9570 |
|
124 |
P |
M |
0.8362 |
|
125 |
P |
M |
0.0000 |
|
126 |
S |
M |
-1.0148 |
|
127 |
S |
M |
-1.7042 |
|
128 |
E |
M |
-2.8575 |
|
129 |
E |
M |
-2.5237 |
|
130 |
L |
M |
-2.5046 |
|
131 |
Q |
M |
-2.6212 |
|
132 |
A |
M |
-2.1664 |
|
133 |
N |
M |
-2.9564 |
|
134 |
K |
M |
-3.1370 |
|
135 |
A |
M |
0.0000 |
|
136 |
T |
M |
-0.0697 |
|
137 |
L |
M |
0.0000 |
|
138 |
V |
M |
1.1903 |
|
139 |
C |
M |
0.0000 |
|
140 |
L |
M |
0.8576 |
|
141 |
I |
M |
0.0000 |
|
142 |
S |
M |
-0.7091 |
|
143 |
D |
M |
-1.4799 |
|
144 |
F |
M |
0.0000 |
|
145 |
Y |
M |
0.0000 |
|
146 |
P |
M |
-0.9460 |
|
147 |
G |
M |
-0.7263 |
|
148 |
A |
M |
-0.1093 |
|
149 |
V |
M |
0.0620 |
|
150 |
T |
M |
0.0979 |
|
151 |
V |
M |
0.1462 |
|
152 |
A |
M |
-0.3174 |
|
153 |
W |
M |
0.0000 |
|
154 |
K |
M |
-0.8968 |
|
155 |
A |
M |
-0.9585 |
|
156 |
D |
M |
-1.2626 |
|
157 |
S |
M |
-0.8484 |
|
158 |
S |
M |
-0.5494 |
|
159 |
P |
M |
-0.7674 |
|
160 |
V |
M |
-0.5728 |
|
161 |
K |
M |
-1.4856 |
|
162 |
A |
M |
-0.9127 |
|
163 |
G |
M |
-0.7044 |
|
164 |
V |
M |
-0.5228 |
|
165 |
E |
M |
-1.4120 |
|
166 |
T |
M |
-0.6260 |
|
167 |
T |
M |
-0.4921 |
|
168 |
T |
M |
-0.1699 |
|
169 |
P |
M |
-0.3175 |
|
170 |
S |
M |
-0.6510 |
|
171 |
K |
M |
-1.1602 |
|
172 |
Q |
M |
-1.3500 |
|
173 |
S |
M |
-1.2433 |
|
174 |
N |
M |
-1.6767 |
|
175 |
N |
M |
-1.5988 |
|
176 |
K |
M |
-1.5294 |
|
177 |
Y |
M |
-1.0444 |
|
178 |
A |
M |
-0.6112 |
|
179 |
A |
M |
-0.1589 |
|
180 |
S |
M |
0.0388 |
|
181 |
S |
M |
0.0000 |
|
182 |
Y |
M |
0.2460 |
|
183 |
L |
M |
0.0000 |
|
184 |
S |
M |
-0.5744 |
|
185 |
L |
M |
0.0000 |
|
186 |
T |
M |
-1.8171 |
|
187 |
P |
M |
-2.5616 |
|
188 |
E |
M |
-3.1345 |
|
189 |
Q |
M |
-2.3309 |
|
190 |
W |
M |
0.0000 |
|
191 |
K |
M |
-3.1934 |
|
192 |
S |
M |
-2.4840 |
|
193 |
H |
M |
-2.4936 |
|
194 |
R |
M |
-2.6820 |
|
195 |
S |
M |
-1.5166 |
|
196 |
Y |
M |
0.0000 |
|
197 |
S |
M |
0.0000 |
|
198 |
C |
M |
0.0000 |
|
199 |
Q |
M |
-0.8102 |
|
200 |
V |
M |
0.0000 |
|
201 |
T |
M |
-0.5973 |
|
202 |
H |
M |
0.0000 |
|
203 |
E |
M |
-2.3154 |
|
204 |
G |
M |
-1.3847 |
|
205 |
S |
M |
-0.9156 |
|
206 |
T |
M |
-0.6758 |
|
207 |
V |
M |
-0.6388 |
|
208 |
E |
M |
-1.5896 |
|
209 |
K |
M |
-1.1010 |
|
210 |
T |
M |
-0.4912 |
|
211 |
V |
M |
0.1353 |
|
212 |
A |
M |
-0.5714 |
|
213 |
P |
M |
-0.9544 |
|
214 |
T |
M |
-0.4641 |
|