Chain sequence(s) |
A: NTKYNKEFLLYLAGFVDGNGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLDS B: NTKYNKEFLLYLAGFVDGNGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLDSLS |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
2 | N | A | -2.0359 | |
3 | T | A | -1.7823 | |
4 | K | A | -2.5362 | |
5 | Y | A | 0.0000 | |
6 | N | A | -2.7764 | |
7 | K | A | -2.9358 | |
8 | E | A | -2.9566 | |
9 | F | A | -1.6664 | |
10 | L | A | 0.0000 | |
11 | L | A | 0.0000 | |
12 | Y | A | -0.5240 | |
13 | L | A | 0.0000 | |
14 | A | A | 0.0000 | |
15 | G | A | 0.0000 | |
16 | F | A | 0.0000 | |
17 | V | A | 0.0000 | |
18 | D | A | 0.0000 | |
19 | G | A | 0.0000 | |
20 | N | A | 0.0000 | |
21 | G | A | 0.0000 | |
22 | S | A | 0.0000 | |
23 | I | A | 0.0000 | |
24 | I | A | 0.0000 | |
25 | A | A | 0.0000 | |
26 | Q | A | 0.0000 | |
27 | I | A | 0.0000 | |
28 | K | A | 0.0000 | |
29 | P | A | -0.8072 | |
30 | N | A | -1.5134 | |
31 | Q | A | -2.2187 | |
32 | S | A | -1.5536 | |
33 | Y | A | 0.0000 | |
34 | K | A | -2.7771 | |
35 | F | A | 0.0000 | |
36 | K | A | -2.3571 | |
37 | H | A | 0.0000 | |
38 | Q | A | 0.0000 | |
39 | L | A | 0.1705 | |
40 | S | A | 0.0624 | |
41 | L | A | 0.0000 | |
42 | T | A | 0.0193 | |
43 | F | A | 0.0000 | |
44 | Q | A | 0.0000 | |
45 | V | A | 0.0000 | |
46 | T | A | 0.0000 | |
47 | Q | A | 0.0000 | |
48 | K | A | -1.2229 | |
49 | T | A | -1.5018 | |
50 | Q | A | -1.5180 | |
51 | R | A | -1.0654 | |
52 | R | A | -1.4911 | |
53 | W | A | -0.6129 | |
54 | F | A | 0.0000 | |
55 | L | A | 0.0000 | |
56 | D | A | -1.8548 | |
57 | K | A | -2.6919 | |
58 | L | A | 0.0000 | |
59 | V | A | -1.6055 | |
60 | D | A | -3.1999 | |
61 | E | A | -3.0914 | |
62 | I | A | 0.0000 | |
63 | G | A | -1.5830 | |
64 | V | A | -0.3440 | |
65 | G | A | -0.0202 | |
66 | Y | A | 0.1223 | |
67 | V | A | -0.4212 | |
68 | R | A | -1.1036 | |
69 | D | A | -2.2083 | |
70 | R | A | -1.4138 | |
71 | G | A | -1.2328 | |
72 | S | A | -1.0569 | |
73 | V | A | 0.0000 | |
74 | S | A | 0.0000 | |
75 | D | A | 0.0000 | |
76 | Y | A | 0.0000 | |
77 | I | A | 0.3423 | |
78 | L | A | 0.0000 | |
79 | S | A | -0.2203 | |
80 | E | A | -0.5773 | |
81 | I | A | -0.9410 | |
82 | K | A | -1.9528 | |
83 | P | A | -1.2386 | |
84 | L | A | 0.0000 | |
85 | H | A | -1.4827 | |
86 | N | A | -1.2999 | |
87 | F | A | 0.0000 | |
88 | L | A | 0.0000 | |
89 | T | A | -0.4542 | |
90 | Q | A | -0.8868 | |
91 | L | A | 0.0000 | |
92 | Q | A | -1.0692 | |
93 | P | A | -0.5809 | |
94 | F | A | -0.4665 | |
95 | L | A | 0.0000 | |
96 | K | A | -1.9923 | |
97 | L | A | -1.1018 | |
98 | K | A | -1.3438 | |
99 | Q | A | -2.1151 | |
100 | K | A | -2.4544 | |
101 | Q | A | 0.0000 | |
102 | A | A | 0.0000 | |
103 | N | A | -1.8408 | |
104 | L | A | 0.0000 | |
105 | V | A | 0.0000 | |
106 | L | A | 0.0000 | |
107 | K | A | -1.9628 | |
108 | I | A | 0.0000 | |
109 | I | A | 0.0000 | |
110 | E | A | -2.3628 | |
111 | Q | A | -1.7689 | |
112 | L | A | -1.1767 | |
113 | P | A | -1.2358 | |
114 | S | A | -1.3786 | |
115 | A | A | 0.0000 | |
116 | K | A | -2.2649 | |
117 | E | A | -2.7675 | |
118 | S | A | -2.2397 | |
119 | P | A | -2.4563 | |
120 | D | A | -2.8865 | |
121 | K | A | -2.2732 | |
122 | F | A | 0.0000 | |
123 | L | A | 0.0000 | |
124 | E | A | -1.8037 | |
125 | V | A | 0.0000 | |
126 | C | A | 0.0000 | |
127 | T | A | -0.9899 | |
128 | W | A | -0.6770 | |
129 | V | A | 0.0000 | |
130 | D | A | -1.2226 | |
131 | Q | A | -0.8642 | |
132 | I | A | 0.0000 | |
133 | A | A | 0.0000 | |
134 | A | A | -0.0656 | |
135 | L | A | 0.0845 | |
136 | N | A | 0.0000 | |
137 | D | A | -0.1859 | |
138 | S | A | -0.6520 | |
139 | K | A | -1.1975 | |
140 | T | A | -1.5665 | |
141 | R | A | -2.8654 | |
142 | K | A | -2.6591 | |
143 | T | A | 0.0000 | |
144 | T | A | -1.7745 | |
145 | S | A | 0.0000 | |
146 | E | A | -2.4559 | |
147 | T | A | -1.5605 | |
148 | V | A | 0.0000 | |
149 | R | A | -2.9864 | |
150 | A | A | -1.6154 | |
151 | V | A | -0.9490 | |
152 | L | A | -1.5349 | |
153 | D | A | -2.0462 | |
154 | S | A | -1.0292 | |
302 | N | B | -2.0449 | |
303 | T | B | -1.7296 | |
304 | K | B | -2.5768 | |
305 | Y | B | 0.0000 | |
306 | N | B | -2.6285 | |
307 | K | B | -2.9340 | |
308 | E | B | -2.2256 | |
309 | F | B | -1.3120 | |
310 | L | B | 0.0000 | |
311 | L | B | 0.0000 | |
312 | Y | B | 0.0000 | |
313 | L | B | 0.0000 | |
314 | A | B | 0.0000 | |
315 | G | B | 0.0000 | |
316 | F | B | 0.0000 | |
317 | V | B | 0.0000 | |
318 | D | B | 0.0000 | |
319 | G | B | 0.0000 | |
320 | N | B | 0.0000 | |
321 | G | B | 0.0000 | |
322 | S | B | 0.0000 | |
323 | I | B | 0.0000 | |
324 | I | B | 0.0000 | |
325 | A | B | 0.0000 | |
326 | Q | B | 0.0000 | |
327 | I | B | 0.0000 | |
328 | K | B | 0.0000 | |
329 | P | B | -0.6481 | |
330 | N | B | -1.2441 | |
331 | Q | B | -1.9142 | |
332 | S | B | -1.3673 | |
333 | Y | B | 0.0000 | |
334 | K | B | -2.4600 | |
335 | F | B | 0.0000 | |
336 | K | B | -1.4658 | |
337 | H | B | 0.0000 | |
338 | Q | B | 0.0000 | |
339 | L | B | 0.1524 | |
340 | S | B | 0.0591 | |
341 | L | B | 0.0000 | |
342 | T | B | 0.0296 | |
343 | F | B | 0.0000 | |
344 | Q | B | 0.0000 | |
345 | V | B | 0.0000 | |
346 | T | B | 0.0000 | |
347 | Q | B | 0.0000 | |
348 | K | B | -1.2663 | |
349 | T | B | -1.4828 | |
350 | Q | B | -1.5434 | |
351 | R | B | -1.2478 | |
352 | R | B | -1.7571 | |
353 | W | B | -0.9369 | |
354 | F | B | 0.0000 | |
355 | L | B | 0.0000 | |
356 | D | B | -2.9908 | |
357 | K | B | -3.4846 | |
358 | L | B | 0.0000 | |
359 | V | B | -2.0505 | |
360 | D | B | -3.5759 | |
361 | E | B | -3.3323 | |
362 | I | B | 0.0000 | |
363 | G | B | -1.6112 | |
364 | V | B | -0.3400 | |
365 | G | B | -0.0814 | |
366 | Y | B | -0.0035 | |
367 | V | B | -0.4776 | |
368 | R | B | -1.0825 | |
369 | D | B | -1.9558 | |
370 | R | B | -1.3596 | |
371 | G | B | -1.1956 | |
372 | S | B | -1.0282 | |
373 | V | B | 0.0000 | |
374 | S | B | 0.0000 | |
375 | D | B | 0.0000 | |
376 | Y | B | 0.0000 | |
377 | I | B | 0.3901 | |
378 | L | B | 0.0000 | |
379 | S | B | -0.1918 | |
380 | E | B | -0.5189 | |
381 | I | B | -0.8948 | |
382 | K | B | -1.9325 | |
383 | P | B | -1.2204 | |
384 | L | B | 0.0000 | |
385 | H | B | -1.4314 | |
386 | N | B | -1.2694 | |
387 | F | B | 0.0000 | |
388 | L | B | 0.0000 | |
389 | T | B | -0.4270 | |
390 | Q | B | -0.9285 | |
391 | L | B | 0.0000 | |
392 | Q | B | -0.9999 | |
393 | P | B | -0.5657 | |
394 | F | B | -0.5625 | |
395 | L | B | 0.0000 | |
396 | K | B | -1.6516 | |
397 | L | B | -0.8669 | |
398 | K | B | 0.0000 | |
399 | Q | B | -1.9447 | |
400 | K | B | -2.3436 | |
401 | Q | B | 0.0000 | |
402 | A | B | 0.0000 | |
403 | N | B | -1.6874 | |
404 | L | B | 0.0000 | |
405 | V | B | 0.0000 | |
406 | L | B | 0.0000 | |
407 | K | B | -1.9206 | |
408 | I | B | 0.0000 | |
409 | I | B | 0.0000 | |
410 | E | B | -2.3748 | |
411 | Q | B | -1.8000 | |
412 | L | B | -1.2356 | |
413 | P | B | -1.3034 | |
414 | S | B | -1.4471 | |
415 | A | B | 0.0000 | |
416 | K | B | -2.1608 | |
417 | E | B | -2.7013 | |
418 | S | B | -1.9678 | |
419 | P | B | -2.3187 | |
420 | D | B | -2.7044 | |
421 | K | B | -2.1418 | |
422 | F | B | 0.0000 | |
423 | L | B | -1.6123 | |
424 | E | B | -1.7940 | |
425 | V | B | 0.0000 | |
426 | C | B | 0.0000 | |
427 | T | B | -0.9638 | |
428 | W | B | -0.6800 | |
429 | V | B | 0.0000 | |
430 | D | B | -1.1337 | |
431 | Q | B | -0.9613 | |
432 | I | B | 0.0000 | |
433 | A | B | -0.3208 | |
434 | A | B | -0.1083 | |
435 | L | B | 0.0815 | |
436 | N | B | 0.0000 | |
437 | D | B | 0.0000 | |
438 | S | B | -0.2790 | |
439 | K | B | -0.8109 | |
440 | T | B | -0.8289 | |
441 | R | B | -1.3448 | |
442 | K | B | -1.9133 | |
443 | T | B | 0.0000 | |
444 | T | B | -1.4302 | |
445 | S | B | 0.0000 | |
446 | E | B | -2.2600 | |
447 | T | B | -1.4351 | |
448 | V | B | 0.0000 | |
449 | R | B | -2.4553 | |
450 | A | B | -1.2865 | |
451 | V | B | -0.5848 | |
452 | L | B | 0.0000 | |
453 | D | B | -1.6781 | |
454 | S | B | -0.4534 | |
455 | L | B | 0.5572 | |
456 | S | B | -0.1238 |