Chain sequence(s) |
A: SQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNN C: SQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNN B: GSGTMENLSRRLKVTGDLFDIMSG |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
2 | S | A | -1.9278 | |
3 | Q | A | -2.5962 | |
4 | S | A | -1.9102 | |
5 | N | A | 0.0000 | |
6 | R | A | -3.1446 | |
7 | E | A | -2.7599 | |
8 | L | A | 0.0000 | |
9 | V | A | 0.0000 | |
10 | V | A | -0.9070 | |
11 | D | A | -0.7987 | |
12 | F | A | 0.0000 | |
13 | L | A | 0.0000 | |
14 | S | A | 0.0010 | |
15 | Y | A | -0.2791 | |
16 | K | A | 0.0000 | |
17 | L | A | 0.0000 | |
18 | S | A | -1.2701 | |
19 | Q | A | -1.9880 | |
20 | K | A | -2.5539 | |
21 | G | A | -1.7557 | |
22 | Y | A | -0.9101 | |
23 | S | A | -0.5907 | |
24 | W | A | -0.1453 | |
25 | S | A | -0.5360 | |
26 | Q | A | -1.4714 | |
83 | M | A | -0.8878 | |
84 | A | A | -0.4601 | |
85 | A | A | -1.1121 | |
86 | V | A | 0.0000 | |
87 | K | A | -0.8348 | |
88 | Q | A | -1.1812 | |
89 | A | A | 0.0000 | |
90 | L | A | 0.0000 | |
91 | R | A | -0.9784 | |
92 | E | A | -1.6123 | |
93 | A | A | 0.0000 | |
94 | G | A | 0.0000 | |
95 | D | A | -1.4286 | |
96 | E | A | -1.7559 | |
97 | F | A | 0.0000 | |
98 | E | A | -1.7186 | |
99 | L | A | -1.7693 | |
100 | R | A | -2.2679 | |
101 | Y | A | 0.0000 | |
102 | R | A | -3.0452 | |
103 | R | A | -2.9510 | |
104 | A | A | -1.5809 | |
105 | F | A | -1.0538 | |
106 | S | A | -1.3373 | |
107 | D | A | -1.7386 | |
108 | L | A | 0.0000 | |
109 | T | A | -0.6983 | |
110 | S | A | -1.5271 | |
111 | Q | A | -1.7285 | |
112 | L | A | 0.0000 | |
113 | H | A | -1.4400 | |
114 | I | A | 0.0000 | |
115 | T | A | -0.6652 | |
116 | P | A | -0.5064 | |
117 | G | A | -0.6913 | |
118 | T | A | -0.7213 | |
119 | A | A | 0.0000 | |
120 | Y | A | -0.6072 | |
121 | Q | A | -1.4897 | |
122 | S | A | 0.0000 | |
123 | F | A | 0.0000 | |
124 | E | A | -1.6410 | |
125 | Q | A | -1.7447 | |
126 | V | A | 0.0000 | |
127 | V | A | 0.0000 | |
128 | N | A | -2.1431 | |
129 | E | A | -2.2993 | |
130 | L | A | 0.0000 | |
131 | F | A | -1.7077 | |
132 | R | A | -2.9373 | |
133 | D | A | -2.7893 | |
134 | G | A | -1.4480 | |
135 | V | A | -0.5840 | |
136 | N | A | -0.0477 | |
137 | W | A | 0.0000 | |
138 | G | A | 0.0000 | |
139 | R | A | 0.0000 | |
140 | I | A | 0.0000 | |
141 | V | A | 0.0000 | |
142 | A | A | 0.0000 | |
143 | F | A | 0.0000 | |
144 | F | A | 0.0000 | |
145 | S | A | 0.0000 | |
146 | F | A | 0.0000 | |
147 | G | A | 0.0000 | |
148 | G | A | 0.0000 | |
149 | A | A | 0.0000 | |
150 | L | A | 0.0000 | |
151 | C | A | 0.0000 | |
152 | V | A | 0.0000 | |
153 | E | A | 0.0000 | |
154 | S | A | 0.0000 | |
155 | V | A | -2.0927 | |
156 | D | A | -3.3746 | |
157 | K | A | -3.5537 | |
158 | E | A | -3.1395 | |
159 | M | A | -1.5174 | |
160 | Q | A | -1.4056 | |
161 | V | A | 0.6712 | |
162 | L | A | 0.0000 | |
163 | V | A | 0.0000 | |
164 | S | A | -0.5176 | |
165 | R | A | -1.1480 | |
166 | I | A | 0.0000 | |
167 | A | A | 0.0000 | |
168 | A | A | -0.7471 | |
169 | W | A | -0.4213 | |
170 | M | A | 0.0000 | |
171 | A | A | 0.0000 | |
172 | T | A | -1.0400 | |
173 | Y | A | -1.1225 | |
174 | L | A | 0.0000 | |
175 | N | A | -2.1587 | |
176 | D | A | -2.5945 | |
177 | H | A | -2.0811 | |
178 | L | A | 0.0000 | |
179 | E | A | -1.9511 | |
180 | P | A | -1.9026 | |
181 | W | A | -1.4450 | |
182 | I | A | 0.0000 | |
183 | Q | A | -2.5543 | |
184 | E | A | -2.9204 | |
185 | N | A | -2.4094 | |
186 | G | A | -2.0210 | |
187 | G | A | -1.8397 | |
188 | W | A | -1.4454 | |
189 | D | A | -2.3423 | |
190 | T | A | -1.5834 | |
191 | F | A | 0.0000 | |
192 | V | A | -1.4828 | |
193 | E | A | -1.9085 | |
194 | L | A | -0.6578 | |
195 | Y | A | 0.0000 | |
196 | G | A | -1.7381 | |
197 | N | A | -2.5091 | |
198 | N | A | -2.1385 | |
105 | G | B | -1.0152 | |
106 | S | B | -1.0961 | |
107 | G | B | -1.1721 | |
108 | T | B | -1.4745 | |
109 | M | B | -1.6179 | |
110 | E | B | -2.1212 | |
111 | N | B | -2.1474 | |
112 | L | B | 0.0000 | |
113 | S | B | 0.0000 | |
114 | R | B | -2.2035 | |
115 | R | B | -1.2636 | |
116 | L | B | 0.0000 | |
117 | K | B | -0.2432 | |
118 | V | B | 1.0111 | |
119 | T | B | 0.0000 | |
120 | G | B | 0.0000 | |
121 | D | B | 1.0830 | |
122 | L | B | 1.8771 | |
123 | F | B | 0.0000 | |
124 | D | B | 1.1220 | |
125 | I | B | 2.2008 | |
126 | M | B | 1.6235 | |
127 | S | B | 0.7115 | |
128 | G | B | 0.3895 | |
2 | S | C | -1.5369 | |
3 | Q | C | -2.3631 | |
4 | S | C | -1.8482 | |
5 | N | C | 0.0000 | |
6 | R | C | -2.9311 | |
7 | E | C | -2.4811 | |
8 | L | C | 0.0000 | |
9 | V | C | 0.0000 | |
10 | V | C | -0.7541 | |
11 | D | C | -0.7484 | |
12 | F | C | 0.0000 | |
13 | L | C | 0.0000 | |
14 | S | C | 0.0058 | |
15 | Y | C | -0.3312 | |
16 | K | C | 0.0000 | |
17 | L | C | 0.0000 | |
18 | S | C | -1.1504 | |
19 | Q | C | -1.8057 | |
20 | K | C | -2.2842 | |
21 | G | C | -1.5992 | |
22 | Y | C | -0.7815 | |
23 | S | C | -0.5136 | |
24 | W | C | -0.0790 | |
25 | S | C | -0.5046 | |
26 | Q | C | -1.3284 | |
83 | M | C | -0.8255 | |
84 | A | C | -0.5665 | |
85 | A | C | -0.8034 | |
86 | V | C | 0.0000 | |
87 | K | C | -0.7470 | |
88 | Q | C | -0.8580 | |
89 | A | C | 0.0000 | |
90 | L | C | 0.0000 | |
91 | R | C | 0.0000 | |
92 | E | C | -1.3904 | |
93 | A | C | 0.0000 | |
94 | G | C | 0.0000 | |
95 | D | C | -1.2585 | |
96 | E | C | -1.7456 | |
97 | F | C | -1.0431 | |
98 | E | C | -1.2222 | |
99 | L | C | -1.5035 | |
100 | R | C | -2.4031 | |
101 | Y | C | -1.4021 | |
102 | R | C | -2.3036 | |
103 | R | C | -2.5787 | |
104 | A | C | -0.8764 | |
105 | F | C | 0.3503 | |
106 | S | C | -0.5006 | |
107 | D | C | -1.2211 | |
108 | L | C | -0.3266 | |
109 | T | C | -0.6497 | |
110 | S | C | -1.3855 | |
111 | Q | C | -1.4565 | |
112 | L | C | -0.6888 | |
113 | H | C | -1.1442 | |
114 | I | C | 0.0000 | |
115 | T | C | -0.5557 | |
116 | P | C | -0.2569 | |
117 | G | C | -0.6175 | |
118 | T | C | -0.6529 | |
119 | A | C | 0.0000 | |
120 | Y | C | -0.5974 | |
121 | Q | C | -1.5273 | |
122 | S | C | -1.0761 | |
123 | F | C | 0.0000 | |
124 | E | C | -1.8108 | |
125 | Q | C | -2.1786 | |
126 | V | C | -1.3071 | |
127 | V | C | 0.0000 | |
128 | N | C | -2.4879 | |
129 | E | C | -3.1106 | |
130 | L | C | -1.7936 | |
131 | F | C | 0.0000 | |
132 | R | C | -3.3234 | |
133 | D | C | -3.0241 | |
134 | G | C | -1.8506 | |
135 | V | C | -1.0137 | |
136 | N | C | -1.0616 | |
137 | W | C | 0.0000 | |
138 | G | C | -0.6745 | |
139 | R | C | -0.9000 | |
140 | I | C | 0.0000 | |
141 | V | C | 0.0000 | |
142 | A | C | -0.1881 | |
143 | F | C | 0.0000 | |
144 | F | C | 0.0000 | |
145 | S | C | 0.0000 | |
146 | F | C | 0.2993 | |
147 | G | C | 0.0000 | |
148 | G | C | 0.0000 | |
149 | A | C | 0.0000 | |
150 | L | C | 0.0000 | |
151 | C | C | 0.0000 | |
152 | V | C | 0.0000 | |
153 | E | C | 0.0000 | |
154 | S | C | 0.0000 | |
155 | V | C | -2.0181 | |
156 | D | C | -3.0737 | |
157 | K | C | -3.4147 | |
158 | E | C | -3.0733 | |
159 | M | C | -1.5360 | |
160 | Q | C | -1.4492 | |
161 | V | C | 0.6305 | |
162 | L | C | 0.0000 | |
163 | V | C | 0.0000 | |
164 | S | C | -0.5553 | |
165 | R | C | -1.1062 | |
166 | I | C | 0.0000 | |
167 | A | C | 0.0000 | |
168 | A | C | -0.6947 | |
169 | W | C | -0.3882 | |
170 | M | C | 0.0000 | |
171 | A | C | 0.0000 | |
172 | T | C | -1.0085 | |
173 | Y | C | -1.0607 | |
174 | L | C | 0.0000 | |
175 | N | C | -2.1511 | |
176 | D | C | -2.5978 | |
177 | H | C | -2.0466 | |
178 | L | C | 0.0000 | |
179 | E | C | -1.9343 | |
180 | P | C | -1.8922 | |
181 | W | C | -1.5648 | |
182 | I | C | 0.0000 | |
183 | Q | C | -2.5694 | |
184 | E | C | -2.9067 | |
185 | N | C | -2.4209 | |
186 | G | C | -1.9359 | |
187 | G | C | -1.6659 | |
188 | W | C | -1.0966 | |
189 | D | C | -1.7310 | |
190 | T | C | -1.1086 | |
191 | F | C | 0.0000 | |
192 | V | C | -0.7980 | |
193 | E | C | -1.3029 | |
194 | L | C | 0.4772 | |
195 | Y | C | -0.0247 | |
196 | G | C | -1.2334 | |
197 | N | C | -2.0885 | |
198 | N | C | -1.9841 |