Chain sequence(s) |
A: LLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDE C: KSLPSYLNGVMPPTQSFAPDPKYVSSVPCILPIIENGKVCSTHLLP |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
703 | L | A | 1.5358 | |
704 | L | A | 0.0000 | |
705 | R | A | -0.4567 | |
706 | I | A | 0.8904 | |
707 | L | A | 0.0000 | |
708 | K | A | -2.5625 | |
709 | E | A | -2.7817 | |
710 | T | A | -2.0710 | |
711 | E | A | -2.0972 | |
712 | F | A | 0.0000 | |
713 | K | A | -2.2642 | |
714 | K | A | -1.2341 | |
715 | I | A | -0.0950 | |
716 | K | A | -0.5312 | |
717 | V | A | 1.4893 | |
718 | L | A | 1.5502 | |
719 | G | A | 0.6023 | |
720 | S | A | 0.4903 | |
721 | G | A | -0.1782 | |
722 | A | A | -0.5970 | |
723 | F | A | -0.5718 | |
724 | G | A | 0.0000 | |
725 | T | A | 0.0000 | |
726 | V | A | 0.5535 | |
727 | Y | A | 0.3015 | |
728 | K | A | -0.5026 | |
729 | G | A | 0.0000 | |
730 | L | A | -0.6737 | |
731 | W | A | 0.0000 | |
732 | I | A | -0.6388 | |
733 | P | A | -1.3702 | |
734 | E | A | -2.5101 | |
735 | G | A | -1.9132 | |
736 | E | A | -2.1564 | |
738 | V | A | 0.3505 | |
739 | K | A | -0.7053 | |
740 | I | A | 0.0344 | |
741 | P | A | -0.2055 | |
742 | V | A | 0.0000 | |
743 | A | A | 0.0000 | |
744 | I | A | 0.0000 | |
745 | K | A | 0.0000 | |
746 | E | A | -0.4694 | |
747 | L | A | 0.0000 | |
748 | R | A | -1.9144 | |
749 | E | A | -1.9512 | |
750 | A | A | -1.0396 | |
751 | T | A | -1.3379 | |
752 | S | A | -1.3097 | |
753 | P | A | -1.7119 | |
754 | K | A | -2.5406 | |
755 | A | A | -1.9815 | |
756 | N | A | -1.8197 | |
757 | K | A | -2.7585 | |
758 | E | A | -1.8546 | |
759 | I | A | 0.0000 | |
760 | L | A | -0.6437 | |
761 | D | A | -1.0988 | |
762 | E | A | 0.0000 | |
763 | A | A | 0.0000 | |
764 | Y | A | 0.7478 | |
765 | V | A | 0.0000 | |
766 | M | A | 0.0000 | |
767 | A | A | 0.0000 | |
768 | S | A | -0.1325 | |
769 | V | A | 0.0000 | |
770 | D | A | -2.1424 | |
771 | N | A | -1.4672 | |
772 | P | A | -1.1893 | |
773 | H | A | 0.0000 | |
774 | V | A | 0.0000 | |
775 | C | A | 0.0000 | |
776 | R | A | -1.4875 | |
777 | L | A | 0.0000 | |
778 | L | A | -0.1140 | |
779 | G | A | 0.0000 | |
780 | I | A | 0.0000 | |
781 | C | A | 0.0000 | |
782 | L | A | 0.4590 | |
783 | T | A | -0.2850 | |
784 | S | A | -0.2320 | |
785 | T | A | -0.4829 | |
786 | V | A | 0.0000 | |
787 | Q | A | 0.0000 | |
788 | L | A | 0.0000 | |
789 | I | A | 0.0000 | |
790 | T | A | 0.0000 | |
791 | Q | A | -0.9361 | |
792 | L | A | 0.0000 | |
793 | M | A | -0.1468 | |
794 | P | A | 0.2745 | |
795 | F | A | 1.2717 | |
796 | G | A | 0.2720 | |
797 | C | A | -0.4873 | |
798 | L | A | 0.0000 | |
799 | L | A | 0.0000 | |
800 | D | A | -2.8168 | |
801 | Y | A | 0.0000 | |
802 | V | A | 0.0000 | |
803 | R | A | -3.7560 | |
804 | E | A | -4.2632 | |
805 | H | A | -4.2404 | |
806 | K | A | -4.4161 | |
807 | D | A | -4.1647 | |
808 | N | A | -3.2224 | |
809 | I | A | 0.0000 | |
810 | G | A | -1.6970 | |
811 | S | A | 0.0000 | |
812 | Q | A | -1.9319 | |
813 | Y | A | -0.8746 | |
814 | L | A | 0.0000 | |
815 | L | A | 0.0000 | |
816 | N | A | -0.9391 | |
817 | W | A | 0.0000 | |
818 | C | A | 0.0000 | |
819 | V | A | -0.2371 | |
820 | Q | A | -0.6159 | |
821 | I | A | 0.0000 | |
822 | A | A | 0.0000 | |
823 | K | A | -1.0190 | |
824 | G | A | 0.0000 | |
825 | M | A | 0.0000 | |
826 | N | A | -1.9223 | |
827 | Y | A | -1.5698 | |
828 | L | A | 0.0000 | |
829 | E | A | -2.1827 | |
830 | D | A | -2.5367 | |
831 | R | A | -1.8846 | |
832 | R | A | -2.2443 | |
833 | L | A | 0.0000 | |
834 | V | A | 0.0000 | |
835 | H | A | 0.0000 | |
836 | R | A | -0.3362 | |
837 | D | A | -0.3964 | |
838 | L | A | 0.0000 | |
839 | A | A | 0.0000 | |
840 | A | A | 0.0000 | |
841 | R | A | -1.3372 | |
842 | N | A | -0.6360 | |
843 | V | A | 0.0000 | |
844 | L | A | -0.3328 | |
845 | V | A | 0.0000 | |
846 | K | A | -1.3393 | |
847 | T | A | -0.8428 | |
848 | P | A | -0.7995 | |
849 | Q | A | -1.6989 | |
850 | H | A | -1.3414 | |
851 | V | A | 0.0000 | |
852 | K | A | -0.7513 | |
853 | I | A | 0.0000 | |
854 | T | A | 0.0000 | |
855 | D | A | -0.2258 | |
856 | F | A | 0.2012 | |
857 | G | A | 0.0639 | |
858 | L | A | 0.1434 | |
859 | A | A | 0.0000 | |
860 | K | A | -0.5830 | |
861 | L | A | -0.5579 | |
862 | L | A | 0.0000 | |
863 | G | A | -1.6839 | |
864 | A | A | -1.6323 | |
865 | E | A | -3.0932 | |
866 | E | A | -3.6622 | |
867 | K | A | -3.5494 | |
868 | E | A | -3.2791 | |
869 | Y | A | -1.9716 | |
870 | H | A | -1.9570 | |
871 | A | A | -1.8973 | |
872 | E | A | -2.2352 | |
873 | G | A | -1.7585 | |
874 | G | A | -1.7980 | |
875 | K | A | -1.5230 | |
876 | V | A | -0.8998 | |
877 | P | A | -0.5628 | |
878 | I | A | 0.0000 | |
879 | K | A | -0.8766 | |
880 | W | A | 0.0000 | |
881 | M | A | 0.0000 | |
882 | A | A | 0.0000 | |
883 | L | A | 0.0000 | |
884 | E | A | -0.5447 | |
885 | S | A | 0.0000 | |
886 | I | A | 0.0000 | |
887 | L | A | 0.3534 | |
888 | H | A | -1.0771 | |
889 | R | A | -1.3816 | |
890 | I | A | -1.2751 | |
891 | Y | A | 0.0000 | |
892 | T | A | 0.0000 | |
893 | H | A | -1.2752 | |
894 | Q | A | 0.0000 | |
895 | S | A | 0.0000 | |
896 | D | A | 0.0000 | |
897 | V | A | 0.0000 | |
898 | W | A | 0.0000 | |
899 | S | A | 0.0000 | |
900 | Y | A | 0.0000 | |
901 | G | A | 0.0000 | |
902 | V | A | 0.0000 | |
903 | T | A | 0.0000 | |
904 | V | A | 0.0000 | |
905 | W | A | 0.0000 | |
906 | E | A | 0.0000 | |
907 | L | A | 0.0000 | |
908 | M | A | 0.0000 | |
909 | T | A | -0.5240 | |
910 | F | A | -1.6258 | |
911 | G | A | 0.0000 | |
912 | S | A | -1.3713 | |
913 | K | A | -2.4078 | |
914 | P | A | 0.0000 | |
915 | Y | A | 0.0000 | |
916 | D | A | -2.6179 | |
917 | G | A | -1.5616 | |
918 | I | A | -1.0914 | |
919 | P | A | -1.0862 | |
920 | A | A | -0.8097 | |
921 | S | A | -0.3598 | |
922 | E | A | -1.3685 | |
923 | I | A | 0.0000 | |
924 | S | A | 0.0000 | |
925 | S | A | -0.7356 | |
926 | I | A | -1.0601 | |
927 | L | A | 0.0000 | |
928 | E | A | -1.1709 | |
929 | K | A | -2.0126 | |
930 | G | A | 0.0000 | |
931 | E | A | -1.1146 | |
932 | R | A | 0.0000 | |
933 | L | A | 0.0000 | |
934 | P | A | 0.0000 | |
935 | Q | A | 0.0805 | |
936 | P | A | 0.0000 | |
937 | P | A | 0.2921 | |
938 | I | A | 0.0000 | |
939 | C | A | 0.0000 | |
940 | T | A | 0.0000 | |
941 | I | A | 0.2156 | |
942 | D | A | -0.8098 | |
943 | V | A | 0.0000 | |
944 | Y | A | 0.0000 | |
945 | M | A | 0.0738 | |
946 | I | A | -0.2861 | |
947 | M | A | 0.0000 | |
948 | V | A | 0.0000 | |
949 | K | A | -1.1803 | |
950 | C | A | 0.0000 | |
951 | W | A | 0.0000 | |
952 | M | A | -1.3596 | |
953 | I | A | -1.2794 | |
954 | D | A | -2.4395 | |
955 | A | A | -1.8919 | |
956 | D | A | -2.3031 | |
957 | S | A | -1.8672 | |
958 | R | A | 0.0000 | |
959 | P | A | 0.0000 | |
960 | K | A | -1.9716 | |
961 | F | A | 0.0000 | |
962 | R | A | -2.6412 | |
963 | E | A | -2.1563 | |
964 | L | A | 0.0000 | |
965 | I | A | -1.0010 | |
966 | I | A | -0.5421 | |
967 | E | A | -1.4005 | |
968 | F | A | 0.0000 | |
969 | S | A | -1.4783 | |
970 | K | A | -2.5885 | |
971 | M | A | 0.0000 | |
972 | A | A | 0.0000 | |
973 | R | A | -3.7686 | |
974 | D | A | -3.9268 | |
975 | P | A | 0.0000 | |
976 | Q | A | -2.8284 | |
977 | R | A | -3.0858 | |
978 | Y | A | -1.5495 | |
979 | L | A | 0.0000 | |
980 | V | A | -0.6367 | |
981 | I | A | -0.9683 | |
982 | Q | A | -1.8949 | |
983 | G | A | -1.9173 | |
984 | D | A | -2.3153 | |
985 | E | A | -2.4334 | |
336 | K | C | -1.6363 | |
337 | S | C | -0.7180 | |
338 | L | C | -0.1161 | |
339 | P | C | 0.0380 | |
340 | S | C | 0.1072 | |
341 | Y | C | 1.0025 | |
342 | L | C | 1.4104 | |
343 | N | C | -0.1127 | |
344 | G | C | 0.3371 | |
345 | V | C | 1.6869 | |
346 | M | C | 0.7103 | |
347 | P | C | -0.0793 | |
348 | P | C | -0.9321 | |
349 | T | C | -0.6455 | |
350 | Q | C | -0.6179 | |
351 | S | C | -0.7661 | |
352 | F | C | -0.6357 | |
353 | A | C | -0.9401 | |
354 | P | C | -0.9259 | |
355 | D | C | -1.1632 | |
356 | P | C | -1.3746 | |
357 | K | C | -1.9548 | |
358 | Y | C | 0.0000 | |
359 | V | C | -1.0490 | |
360 | S | C | -1.0492 | |
361 | S | C | -0.7213 | |
376 | V | C | 1.6129 | |
377 | P | C | 1.1707 | |
378 | C | C | 1.3435 | |
379 | I | C | 1.1398 | |
380 | L | C | 1.7640 | |
381 | P | C | 0.3711 | |
382 | I | C | 0.1161 | |
383 | I | C | -0.2911 | |
384 | E | C | -1.9921 | |
385 | N | C | -2.1354 | |
386 | G | C | -1.4129 | |
388 | K | C | -1.2245 | |
389 | V | C | 0.5124 | |
390 | C | C | 0.1780 | |
391 | S | C | -0.1619 | |
392 | T | C | -0.7251 | |
393 | H | C | -0.5555 | |
396 | L | C | 0.3277 | |
397 | L | C | 0.9168 | |
398 | P | C | 0.5481 |