Project name: 7cbe9f5cc9c6849

Status: done

submitted: 2017-03-17 14:40:30, status changed: 2017-03-17 14:53:45
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Chain sequence(s) A: QLVSFAGICVFVALLFACSKHHCAVSWRAVSWGLGLQFVLGLLVIRTEPGFIAFEWLGEQIRIFLSYTKAGSSFVFGEALVKDVFAFQVLPIIVFFSCVISVLYHVGLMQWVILKIAWLMQVTMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDATSLIAASVMAAPCALALSKLVYPEVEESKFRREEGVKLTYGDAQNLIEAASTGAAISVKVVANIAANLIAFLAVLDFINAALSWLGDMVDIQGLSFQLICSYILRPVAFLMGVAWEDCPVVAELLGIKLFLNEFVAYQDLSKYKQRRLAGAEEWVGDRKQWISVRAEVLTTFALCGFANFSSIGIMLGGLTSMVPQRKSDFSQIVLRALFTGACVSLVNACMAG
Distance of aggregation 10 Å
Dynamic mode No
Show buried residues

Minimal score value
-3.1339
Maximal score value
2.8929
Average score
0.1475
Total score value
60.642

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
178 Q A 0.3323
179 L A 2.1965
180 V A 2.7667
181 S A 0.0000
182 F A 2.3133
183 A A 2.0526
184 G A 0.0000
185 I A 1.6406
186 C A 2.0441
187 V A 1.9720
188 F A 0.0000
189 V A 1.4773
190 A A 1.4683
191 L A 1.7756
192 L A 0.0000
193 F A 0.4411
194 A A 0.2220
195 C A -0.1242
196 S A -1.0856
197 K A -2.0971
198 H A -1.7451
199 H A -1.3907
200 C A -0.0962
201 A A -0.0907
202 V A 0.0000
203 S A -0.3714
204 W A 0.3539
205 R A -1.2871
206 A A 0.0000
207 V A 0.0000
208 S A -0.0876
209 W A 0.3200
210 G A 0.0000
211 L A 0.7604
212 G A 0.8884
213 L A 1.1628
214 Q A 0.0000
215 F A 1.8513
216 V A 2.6495
217 L A 1.7896
218 G A 0.0000
219 L A 1.7286
220 L A 1.5553
221 V A 0.0000
222 I A 0.6311
223 R A -0.9422
224 T A -0.5193
225 E A -1.1391
226 P A 0.0002
227 G A 0.0000
228 F A 1.6283
229 I A 2.2683
230 A A 1.3275
231 F A 0.0000
232 E A 0.4254
233 W A 0.9920
234 L A 0.4650
235 G A 0.0000
236 E A -1.5469
237 Q A -0.7841
238 I A -0.0882
239 R A -0.2962
240 I A 0.6324
241 F A 1.0997
242 L A 0.0000
243 S A 0.6411
244 Y A 1.4818
245 T A 0.0000
246 K A 0.4087
247 A A 0.6890
248 G A 0.9598
249 S A 0.0000
250 S A 1.3961
251 F A 2.5112
252 V A 2.8929
253 F A 1.9215
254 G A 0.6330
255 E A -1.4346
256 A A 0.0676
257 L A 0.4868
258 V A -0.8080
259 K A -2.2600
260 D A -2.4912
261 V A 0.0047
262 F A 1.9174
263 A A 1.8095
264 F A 2.6663
265 Q A 1.2717
266 V A 0.0000
267 L A 1.2656
268 P A 1.0830
269 I A 0.0000
270 I A 0.0000
271 V A 1.3333
272 F A 1.1379
273 F A 0.0000
274 S A 1.0031
275 C A 0.9259
276 V A 0.8058
277 I A 0.7791
278 S A 0.0000
279 V A 1.2214
280 L A 1.5034
281 Y A 0.0000
282 H A 1.0217
283 V A 2.2281
284 G A 0.0000
285 L A 2.3451
286 M A 0.0000
287 Q A 0.0000
288 W A 2.1459
289 V A 1.3468
290 I A 0.0000
291 L A 0.8899
292 K A -0.1916
293 I A 0.5266
294 A A 0.0000
295 W A 1.5794
296 L A 1.3223
297 M A 0.0000
298 Q A 0.8802
299 V A 1.6332
300 T A 0.6659
301 M A 0.0000
302 G A -0.4637
303 T A 0.0000
304 T A -0.2783
305 A A 0.0000
306 T A 0.0000
307 E A 0.0000
308 T A 0.0000
309 L A 0.0000
310 S A 0.0000
311 V A 0.0000
312 A A 0.0000
313 G A 0.0000
314 N A 0.0000
315 I A 0.0000
316 F A 0.4071
317 V A 0.0000
318 S A -0.2381
319 Q A 0.0000
320 T A -0.0770
321 E A -0.6914
322 A A 0.0000
323 P A 0.0000
324 L A -0.3431
325 L A 0.0000
326 I A 0.0000
327 R A -1.3357
328 P A -1.3580
329 Y A 0.0000
330 L A 0.0000
331 A A -1.3507
332 D A -2.2684
333 M A 0.0000
334 T A 0.0000
335 L A -0.1936
336 S A 0.0000
337 E A 0.0000
338 V A 0.0000
339 H A 0.0000
340 V A 0.0000
341 V A 0.0000
342 M A 0.0000
343 T A 0.0000
344 G A 0.0000
345 G A 0.0000
346 Y A 0.0000
347 A A 0.0000
348 T A 0.0000
349 I A 0.0000
350 A A 0.0000
351 G A 0.1571
352 S A 0.0000
353 L A 0.0000
354 L A 0.0000
355 G A 0.0000
356 A A 0.0000
357 Y A 0.0000
358 I A 0.0631
359 S A 0.0000
360 F A 0.0000
361 G A 0.0000
362 I A 0.0000
363 D A -0.4228
364 A A 0.0000
365 T A -0.1139
366 S A 0.0000
367 L A 0.0000
368 I A 0.0000
369 A A 0.0000
370 A A 0.0000
371 S A 0.0000
372 V A 0.4350
373 M A 0.0000
374 A A 0.0000
375 A A 0.0000
376 P A 0.0000
377 C A 0.0000
378 A A 0.0000
379 L A 0.0000
380 A A 0.0000
381 L A 0.0000
382 S A 0.0000
383 K A 0.0000
384 L A 0.0000
385 V A 0.0000
386 Y A 0.0000
387 P A 0.0000
388 E A -0.8708
389 V A -0.0567
390 E A -2.1684
391 E A -2.6557
392 S A -2.1190
393 K A -2.4603
394 F A -0.6391
395 R A -2.8194
396 R A -2.6653
397 E A -2.1751
398 E A 0.0000
399 G A -0.3836
400 V A 1.6031
401 K A 1.5540
402 L A 2.4251
403 T A 1.3252
404 Y A 0.3752
405 G A -0.6234
406 D A -0.9247
407 A A -1.0085
408 Q A -1.4924
409 N A -0.4609
410 L A 0.9430
411 I A 1.4480
412 E A -0.4478
413 A A 0.0000
414 A A 0.6045
415 S A 0.2618
416 T A 0.3976
417 G A 0.0000
418 A A 0.8575
419 A A 0.9515
420 I A 1.5068
421 S A 0.0000
422 V A 1.6242
423 K A -0.2422
424 V A 0.7273
425 V A 0.6347
426 A A -0.2518
427 N A -1.0274
428 I A 0.0240
429 A A 0.3088
430 A A 0.4625
431 N A 0.3323
432 L A 0.0000
433 I A 2.3992
434 A A 1.5487
435 F A 1.4672
436 L A 1.3602
437 A A 1.2677
438 V A 1.7180
439 L A 0.0000
440 D A -0.2239
441 F A 1.7491
442 I A 1.3528
443 N A 0.5349
444 A A 0.7383
445 A A 0.9983
446 L A 0.9406
447 S A 0.3149
448 W A 1.3332
449 L A 1.3615
450 G A 0.0000
451 D A -0.7832
452 M A 1.0903
453 V A 1.3624
454 D A -0.8987
455 I A 0.2403
456 Q A -1.0740
457 G A -0.8632
458 L A 0.2302
459 S A 0.3577
460 F A 0.3758
461 Q A 0.3717
462 L A 1.2039
463 I A 1.6362
464 C A 0.0000
465 S A 0.0000
466 Y A 1.8924
467 I A 1.8686
468 L A 0.0000
469 R A 0.1513
470 P A 0.5310
471 V A 0.6280
472 A A 0.0000
473 F A 1.1178
474 L A 1.4801
475 M A 0.0000
476 G A 1.0778
477 V A 0.0000
478 A A 0.0880
479 W A 0.3599
480 E A -1.2911
481 D A -0.6737
482 C A 0.0000
483 P A 0.1977
484 V A -0.1939
485 V A 0.0000
486 A A 0.0000
487 E A -0.0109
488 L A 0.0000
489 L A 0.0000
490 G A 0.0000
491 I A 0.0000
492 K A 0.0000
493 L A 1.5189
494 F A 2.2681
495 L A 1.4040
496 N A 0.6871
497 E A 0.0000
498 F A 0.0000
499 V A 0.0000
500 A A 0.0000
501 Y A 0.0000
502 Q A -0.4800
503 D A -0.7857
504 L A 0.0000
505 S A 0.0000
506 K A -0.9196
507 Y A -0.0235
508 K A 0.0000
509 Q A -1.9520
510 R A -3.1218
511 R A -2.3204
512 L A -1.1329
513 A A -1.5773
514 G A -1.1011
515 A A -1.4863
516 E A 0.0000
517 E A -1.6131
518 W A -0.7739
519 V A 0.0000
520 G A -2.1139
521 D A -3.1339
522 R A -2.8756
523 K A -2.9319
524 Q A -1.9322
525 W A -0.0798
526 I A 0.0242
527 S A 0.5999
528 V A 1.4492
529 R A -0.0717
530 A A 0.0000
531 E A 0.1977
532 V A 0.1858
533 L A 0.0000
534 T A 0.0000
535 T A 0.0000
536 F A 0.0000
537 A A 0.0000
538 L A 0.0000
539 C A 0.0000
540 G A 0.0000
541 F A 0.0000
542 A A 0.0000
543 N A 0.0000
544 F A 2.7879
545 S A 1.2679
546 S A 0.0000
547 I A 0.0000
548 G A 0.6634
549 I A 1.6682
550 M A 0.0000
551 L A -0.0510
552 G A 0.0270
553 G A 0.0460
554 L A 0.0000
555 T A 0.0000
556 S A -0.7311
557 M A -0.5275
558 V A 0.0000
559 P A -1.3646
560 Q A -1.9236
561 R A -1.8513
562 K A -2.3520
563 S A -1.7219
564 D A -1.4697
565 F A 0.0000
566 S A -1.0813
567 Q A -1.4250
568 I A 0.0000
569 V A 0.6871
570 L A 1.6287
571 R A 0.1790
572 A A 0.0000
573 L A 1.2045
574 F A 1.1698
575 T A 0.0000
576 G A 0.0000
577 A A 0.2108
578 C A 0.0000
579 V A 0.0000
580 S A 0.0000
581 L A 0.0000
582 V A 0.0000
583 N A 0.0000
584 A A 0.0000
585 C A 0.0000
586 M A 0.0000
587 A A 0.0000
588 G A -0.2006

 

Laboratory of Theory of Biopolymers 2015