Project name: 5i5k:H
Status: done
submitted: 2019-03-21 13:20:31, status changed: 2019-03-21 13:31:58
Settings
Chain sequence(s)
|
H: QVQLVQSGAEVKKPGASVKVSCKASGYIFSNYWIQWVRQAPGQGLEWMGEILPGSGSTEYTENFKDRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARYFFGSSPNWYFDVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVE
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7649
-
Maximal score value
-
2.7812
-
Average score
-
-0.5213
-
Total score value
-
-115.2025
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
Q |
H |
-0.9378 |
|
2 |
V |
H |
-0.2012 |
|
3 |
Q |
H |
-0.8206 |
|
4 |
L |
H |
0.0000 |
|
5 |
V |
H |
0.2152 |
|
6 |
Q |
H |
-0.2993 |
|
7 |
S |
H |
-0.3942 |
|
8 |
G |
H |
-0.4454 |
|
9 |
A |
H |
0.2491 |
|
10 |
E |
H |
-0.4247 |
|
11 |
V |
H |
-0.1630 |
|
12 |
K |
H |
-1.8583 |
|
13 |
K |
H |
-2.5032 |
|
14 |
P |
H |
-2.4510 |
|
15 |
G |
H |
-1.8086 |
|
16 |
A |
H |
-1.4801 |
|
17 |
S |
H |
-1.7092 |
|
18 |
V |
H |
0.0000 |
|
19 |
K |
H |
-1.8781 |
|
20 |
V |
H |
0.0000 |
|
21 |
S |
H |
-0.5813 |
|
22 |
C |
H |
0.0000 |
|
23 |
K |
H |
-0.5166 |
|
24 |
A |
H |
0.0000 |
|
25 |
S |
H |
-0.2686 |
|
26 |
G |
H |
-0.4480 |
|
27 |
Y |
H |
0.6341 |
|
28 |
I |
H |
1.6439 |
|
29 |
F |
H |
0.5953 |
|
30 |
S |
H |
-0.4210 |
|
31 |
N |
H |
-0.5636 |
|
32 |
Y |
H |
0.6936 |
|
33 |
W |
H |
0.4895 |
|
34 |
I |
H |
0.0000 |
|
35 |
Q |
H |
0.0000 |
|
36 |
W |
H |
0.0000 |
|
37 |
V |
H |
0.0000 |
|
38 |
R |
H |
-0.2982 |
|
39 |
Q |
H |
-0.3142 |
|
40 |
A |
H |
-0.9900 |
|
41 |
P |
H |
-0.7488 |
|
42 |
G |
H |
-1.1305 |
|
43 |
Q |
H |
-1.5961 |
|
44 |
G |
H |
-0.8823 |
|
45 |
L |
H |
0.1346 |
|
46 |
E |
H |
-0.9497 |
|
47 |
W |
H |
-0.0621 |
|
48 |
M |
H |
0.0000 |
|
49 |
G |
H |
0.0000 |
|
50 |
E |
H |
-0.6452 |
|
51 |
I |
H |
0.0000 |
|
52 |
L |
H |
-0.6238 |
|
53 |
P |
H |
0.0000 |
|
54 |
G |
H |
-1.2150 |
|
55 |
S |
H |
-0.8359 |
|
56 |
G |
H |
-0.8254 |
|
57 |
S |
H |
-0.8356 |
|
58 |
T |
H |
-0.9958 |
|
59 |
E |
H |
-2.1751 |
|
60 |
Y |
H |
-2.0107 |
|
61 |
T |
H |
-2.3384 |
|
62 |
E |
H |
-3.4914 |
|
63 |
N |
H |
-2.8525 |
|
64 |
F |
H |
-2.4515 |
|
65 |
K |
H |
-3.7649 |
|
66 |
D |
H |
-3.4955 |
|
67 |
R |
H |
-3.2405 |
|
68 |
V |
H |
-1.8650 |
|
69 |
T |
H |
-1.1645 |
|
70 |
M |
H |
0.0000 |
|
71 |
T |
H |
-1.0524 |
|
72 |
R |
H |
-2.2065 |
|
73 |
D |
H |
-1.6555 |
|
74 |
T |
H |
-1.0047 |
|
75 |
S |
H |
-0.6659 |
|
76 |
T |
H |
-0.6656 |
|
77 |
S |
H |
-0.6077 |
|
78 |
T |
H |
0.0000 |
|
79 |
V |
H |
0.0000 |
|
80 |
Y |
H |
-0.7613 |
|
81 |
M |
H |
0.0000 |
|
82 |
E |
H |
-1.6966 |
|
83 |
L |
H |
0.0000 |
|
84 |
S |
H |
-1.7834 |
|
85 |
S |
H |
-1.6516 |
|
86 |
L |
H |
0.0000 |
|
87 |
R |
H |
-3.2665 |
|
88 |
S |
H |
-2.4834 |
|
89 |
E |
H |
-2.6588 |
|
90 |
D |
H |
-2.0092 |
|
91 |
T |
H |
-1.0512 |
|
92 |
A |
H |
0.0000 |
|
93 |
V |
H |
0.8628 |
|
94 |
Y |
H |
0.0000 |
|
95 |
Y |
H |
0.1510 |
|
96 |
C |
H |
0.0000 |
|
97 |
A |
H |
0.0000 |
|
98 |
R |
H |
0.0000 |
|
99 |
Y |
H |
1.8457 |
|
100 |
F |
H |
2.3355 |
|
101 |
F |
H |
2.7812 |
|
102 |
G |
H |
1.2324 |
|
103 |
S |
H |
0.1615 |
|
104 |
S |
H |
-0.1504 |
|
105 |
P |
H |
0.0185 |
|
106 |
N |
H |
0.5548 |
|
107 |
W |
H |
2.2494 |
|
108 |
Y |
H |
2.3452 |
|
109 |
F |
H |
1.8242 |
|
110 |
D |
H |
0.7358 |
|
111 |
V |
H |
0.5164 |
|
112 |
W |
H |
0.4901 |
|
113 |
G |
H |
-0.2631 |
|
114 |
Q |
H |
-0.7654 |
|
115 |
G |
H |
-0.0650 |
|
116 |
T |
H |
0.0000 |
|
117 |
L |
H |
1.4040 |
|
118 |
V |
H |
0.0000 |
|
119 |
T |
H |
-0.5149 |
|
120 |
V |
H |
-1.3864 |
|
121 |
S |
H |
-1.1224 |
|
122 |
S |
H |
-0.6377 |
|
123 |
A |
H |
-0.5138 |
|
124 |
S |
H |
-0.6987 |
|
125 |
T |
H |
-0.8727 |
|
126 |
K |
H |
-1.4167 |
|
127 |
G |
H |
-1.4757 |
|
128 |
P |
H |
0.0000 |
|
129 |
S |
H |
-0.0847 |
|
130 |
V |
H |
0.5356 |
|
131 |
F |
H |
1.8767 |
|
132 |
P |
H |
0.4374 |
|
133 |
L |
H |
0.7781 |
|
134 |
A |
H |
-0.2185 |
|
135 |
P |
H |
-0.6585 |
|
136 |
S |
H |
-0.8389 |
|
137 |
S |
H |
-1.2674 |
|
138 |
K |
H |
-2.0700 |
|
139 |
S |
H |
-1.3001 |
|
140 |
T |
H |
-1.1227 |
|
141 |
S |
H |
-1.0461 |
|
142 |
G |
H |
-1.1152 |
|
143 |
G |
H |
-0.9307 |
|
144 |
T |
H |
-0.6739 |
|
145 |
A |
H |
0.0000 |
|
146 |
A |
H |
0.0465 |
|
147 |
L |
H |
0.0000 |
|
148 |
G |
H |
0.0000 |
|
149 |
C |
H |
0.0000 |
|
150 |
L |
H |
0.8661 |
|
151 |
V |
H |
0.0000 |
|
152 |
K |
H |
-0.0202 |
|
153 |
D |
H |
-0.6637 |
|
154 |
Y |
H |
0.0000 |
|
155 |
F |
H |
0.0000 |
|
156 |
P |
H |
-1.0985 |
|
157 |
E |
H |
-1.7258 |
|
158 |
P |
H |
-1.3429 |
|
159 |
V |
H |
-0.9116 |
|
160 |
T |
H |
-0.6362 |
|
161 |
V |
H |
-0.3513 |
|
162 |
S |
H |
-0.3723 |
|
163 |
W |
H |
0.0000 |
|
164 |
N |
H |
-0.6287 |
|
165 |
S |
H |
-0.5226 |
|
166 |
G |
H |
-0.5839 |
|
167 |
A |
H |
-0.2616 |
|
168 |
L |
H |
-0.0216 |
|
169 |
T |
H |
-0.3003 |
|
170 |
S |
H |
-0.3825 |
|
171 |
G |
H |
-0.5215 |
|
172 |
V |
H |
-0.2150 |
|
173 |
H |
H |
-0.5010 |
|
174 |
T |
H |
0.4326 |
|
175 |
F |
H |
1.4568 |
|
176 |
P |
H |
0.8949 |
|
177 |
A |
H |
1.2078 |
|
178 |
V |
H |
2.5304 |
|
179 |
L |
H |
2.0676 |
|
180 |
Q |
H |
0.4822 |
|
181 |
S |
H |
-0.1628 |
|
182 |
S |
H |
-0.2293 |
|
183 |
G |
H |
0.0000 |
|
184 |
L |
H |
0.0000 |
|
185 |
Y |
H |
0.6654 |
|
186 |
S |
H |
0.6929 |
|
187 |
L |
H |
0.0000 |
|
188 |
S |
H |
0.6556 |
|
189 |
S |
H |
0.0000 |
|
190 |
V |
H |
0.4545 |
|
191 |
V |
H |
0.0000 |
|
192 |
T |
H |
-0.1971 |
|
193 |
V |
H |
0.0000 |
|
194 |
P |
H |
-0.7499 |
|
195 |
S |
H |
-0.8199 |
|
196 |
S |
H |
-0.8428 |
|
197 |
S |
H |
-0.7975 |
|
198 |
L |
H |
0.0000 |
|
199 |
G |
H |
-1.3163 |
|
200 |
T |
H |
-1.2402 |
|
201 |
Q |
H |
-1.6521 |
|
202 |
T |
H |
-1.3627 |
|
203 |
Y |
H |
0.0000 |
|
204 |
I |
H |
-1.2596 |
|
205 |
C |
H |
0.0000 |
|
206 |
N |
H |
-1.4222 |
|
207 |
V |
H |
0.0000 |
|
208 |
N |
H |
-1.7314 |
|
209 |
H |
H |
0.0000 |
|
210 |
K |
H |
-2.7835 |
|
211 |
P |
H |
-1.8046 |
|
212 |
S |
H |
-1.9903 |
|
213 |
N |
H |
-2.5082 |
|
214 |
T |
H |
-2.0277 |
|
215 |
K |
H |
-2.5759 |
|
216 |
V |
H |
-1.1968 |
|
217 |
D |
H |
-2.2240 |
|
218 |
K |
H |
0.0000 |
|
219 |
R |
H |
-2.6107 |
|
220 |
V |
H |
0.0000 |
|
221 |
E |
H |
-2.4784 |
|