Project name: 1JW4_A_double_10

Status: done

submitted: 2017-05-19 19:30:28, status changed: 2017-05-19 19:46:02
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Chain sequence(s) A: KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTDPKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK
Distance of aggregation 10 Å
Dynamic mode No
Show buried residues

Minimal score value
-5.128
Maximal score value
0.8849
Average score
-1.1129
Total score value
-411.7855

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
1 K A -2.1142
2 I A -1.4401
3 E A -2.8184
4 E A -2.9033
5 G A -2.2344
6 K A -2.1509
7 L A 0.0000
8 V A -0.3005
9 I A 0.0000
10 W A 0.0000
11 I A 0.0000
12 N A -2.1037
13 G A -2.3722
14 D A -2.4241
15 K A -2.0743
16 G A 0.0000
17 Y A -1.5716
18 N A -2.1505
19 G A 0.0000
20 L A 0.0000
21 A A -1.8600
22 E A -3.1062
23 V A 0.0000
24 G A 0.0000
25 K A -4.5783
26 K A -4.3408
27 F A 0.0000
28 E A -5.1280
29 K A -4.8131
30 D A -4.0400
31 T A -3.1068
32 D A -4.1144
33 P A -3.1534
34 K A -3.3485
35 V A -1.8126
36 T A -0.7811
37 V A -0.5466
38 E A -1.4519
39 H A -2.0447
40 P A -2.0715
41 D A -3.3036
42 K A -3.4172
43 L A 0.0000
44 E A -2.6143
45 E A -3.4283
46 K A -2.7347
47 F A 0.0000
48 P A -1.4797
49 Q A -1.7769
50 V A -1.0485
51 A A 0.0000
52 A A -0.5361
53 T A -0.7633
54 G A -0.8718
55 D A -1.5501
56 G A -0.9804
57 P A 0.0000
58 D A 0.0000
59 I A 0.0000
60 I A 0.0000
61 F A 0.0000
62 W A -0.3667
63 A A -0.6258
64 H A 0.0000
65 D A -1.1919
66 R A -2.2119
67 F A 0.0000
68 G A 0.0000
69 G A -1.5041
70 Y A 0.0000
71 A A -1.7460
72 Q A -1.7236
73 S A -1.1183
74 G A -1.1745
75 L A 0.0000
76 L A 0.0000
77 A A -1.2086
78 E A -2.3336
79 I A 0.0000
80 T A -1.6033
81 P A 0.0000
82 D A -2.8961
83 K A -3.1834
84 A A -2.2333
85 F A 0.0000
86 Q A -2.4362
87 D A -3.1511
88 K A -2.4377
89 L A 0.0000
90 Y A -0.8746
91 P A -0.7871
92 F A -0.1919
93 T A 0.0000
94 W A 0.0000
95 D A -1.1881
96 A A 0.0000
97 V A 0.0000
98 R A -1.9359
99 Y A -2.0707
100 N A -2.4483
101 G A -2.3963
102 K A -2.8260
103 L A -1.6336
104 I A 0.0000
105 A A 0.0000
106 Y A 0.0000
107 P A 0.0000
108 I A 0.0000
109 A A 0.0000
110 V A 0.0000
111 E A -1.0441
112 A A 0.0000
113 L A 0.0000
114 S A 0.0000
115 L A 0.0000
116 I A 0.0000
117 Y A 0.0000
118 N A 0.0000
119 K A -2.3428
120 D A -2.5563
121 L A -1.5107
122 L A 0.0000
123 P A -1.6559
124 N A -1.9693
125 P A -1.1642
126 P A 0.0000
127 K A -2.2386
128 T A -2.0478
129 W A 0.0000
130 E A -2.2481
131 E A -2.1076
132 I A 0.0000
133 P A -1.7591
134 A A -1.5930
135 L A -1.5603
136 D A 0.0000
137 K A -3.4389
138 E A -3.3485
139 L A 0.0000
140 K A -3.3029
141 A A -2.5580
142 K A -2.9710
143 G A -2.6652
144 K A -2.6472
145 S A -1.8664
146 A A 0.0000
147 L A 0.0000
148 M A -0.1132
149 F A 0.0000
150 N A 0.0000
151 L A 0.0000
152 Q A -1.0437
153 E A -0.8134
154 P A 0.0000
155 Y A -0.1380
156 F A 0.0000
157 T A 0.0000
158 W A 0.0000
159 P A 0.0000
160 L A 0.0000
161 I A 0.0000
162 A A 0.0000
163 A A 0.0000
164 D A -1.5231
165 G A -0.7650
166 G A 0.0000
167 Y A -0.1551
168 A A 0.0000
169 F A 0.0000
170 K A -1.7081
171 Y A -1.8505
172 E A -3.2976
173 N A -2.8487
174 G A -2.8672
175 K A -3.5128
176 Y A -2.1396
177 D A -2.3465
178 I A -0.6575
179 K A -2.0333
180 D A -1.3989
181 V A 0.0000
182 G A 0.0000
183 V A 0.0000
184 D A -1.9458
185 N A -1.2256
186 A A -0.7424
187 G A 0.0000
188 A A 0.0000
189 K A -1.4665
190 A A -0.8028
191 G A 0.0000
192 L A 0.0000
193 T A -0.5012
194 F A -0.3076
195 L A 0.0000
196 V A 0.0000
197 D A -2.0371
198 L A 0.0000
199 I A -2.5013
200 K A -3.4028
201 N A -3.3072
202 K A -3.4742
203 H A -2.3245
204 M A 0.0000
205 N A -2.6261
206 A A -1.9290
207 D A -2.1395
208 T A 0.0000
209 D A -0.7484
210 Y A 0.3804
211 S A 0.4484
212 I A 0.8849
213 A A 0.0000
214 E A -0.2500
215 A A -0.5953
216 A A 0.0000
217 F A 0.0000
218 N A -2.1477
219 K A -2.5868
220 G A -2.3502
221 E A -2.5492
222 T A 0.0000
223 A A 0.0000
224 M A 0.0000
225 T A 0.0000
226 I A 0.0000
227 N A 0.0000
228 G A 0.0000
229 P A -0.0058
230 W A 0.2591
231 A A 0.0000
232 W A -0.5724
233 S A -1.0294
234 N A -1.8642
235 I A 0.0000
236 D A -2.3659
237 T A -1.6902
238 S A -2.1033
239 K A -2.7171
240 V A -2.3342
241 N A -2.3942
242 Y A -1.4083
243 G A -0.6058
244 V A 0.0000
245 T A -0.2573
246 V A -0.2363
247 L A 0.0000
248 P A 0.0000
249 T A -1.5999
250 F A 0.0000
251 K A -2.4731
252 G A -2.0355
253 Q A -1.7992
254 P A -1.2739
255 S A 0.0000
256 K A -1.0608
257 P A 0.0000
258 F A 0.0000
259 V A 0.0000
260 G A -0.5032
261 V A 0.0000
262 L A 0.0000
263 S A 0.0000
264 A A 0.0000
265 G A 0.0000
266 I A 0.0000
267 N A 0.0000
268 A A -0.5550
269 A A -0.3941
270 S A 0.0000
271 P A -1.3341
272 N A 0.0000
273 K A -1.8802
274 E A -2.5380
275 L A -1.7946
276 A A 0.0000
277 K A -2.1803
278 E A -2.5961
279 F A 0.0000
280 L A 0.0000
281 E A -1.4796
282 N A -1.8692
283 Y A -1.5559
284 L A 0.0000
285 L A 0.0000
286 T A -1.7463
287 D A -2.3900
288 E A -2.5143
289 G A 0.0000
290 L A 0.0000
291 E A -2.3414
292 A A -2.3597
293 V A 0.0000
294 N A -1.8532
295 K A -2.7350
296 D A -2.4147
297 K A -2.1583
298 P A -1.4791
299 L A -0.7982
300 G A -0.3310
301 A A 0.0000
302 V A 0.0000
303 A A 0.0000
304 L A 0.0000
305 K A -2.1670
306 S A -1.8928
307 Y A 0.0000
308 E A 0.0000
309 E A -3.2682
310 E A -3.3837
311 L A -2.1644
312 A A -2.1536
313 K A -2.7741
314 D A -1.8481
315 P A -1.0803
316 R A -0.9639
317 I A -0.8092
318 A A -1.1268
319 A A 0.0000
320 T A 0.0000
321 M A 0.0000
322 E A -2.0269
323 N A 0.0000
324 A A 0.0000
325 Q A -2.1784
326 K A -2.1040
327 G A -1.3877
328 E A -0.5486
329 I A -0.2175
330 M A 0.1038
331 P A 0.0000
332 N A -0.7255
333 I A -0.5448
334 P A -0.7851
335 Q A -0.5631
336 M A 0.0000
337 S A -0.0218
338 A A -0.2427
339 F A 0.0000
340 W A 0.3733
341 Y A 0.7905
342 A A 0.0000
343 V A 0.0000
344 R A -0.6499
345 T A -0.2461
346 A A 0.0000
347 V A 0.0000
348 I A -0.5315
349 N A -1.0698
350 A A 0.0000
351 A A -1.1754
352 S A -1.5259
353 G A -1.6676
354 R A -2.1843
355 Q A -1.8072
356 T A -1.6016
357 V A -1.8668
358 D A -3.1853
359 E A -3.1805
360 A A 0.0000
361 L A 0.0000
362 K A -3.5180
363 D A -2.8407
364 A A 0.0000
365 Q A -2.0704
366 T A -2.0832
367 R A -2.3273
368 I A 0.0000
369 T A -1.6785
370 K A -2.4805

 

Laboratory of Theory of Biopolymers 2015