| Chain sequence(s) |
A: MTSKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP B: MTSKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | M | A | 0.6738 | |
| 2 | T | A | -0.0189 | |
| 3 | S | A | -0.5639 | |
| 4 | K | A | -0.9734 | |
| 5 | M | A | -1.3695 | |
| 6 | S | A | -1.7608 | |
| 7 | Q | A | -2.0094 | |
| 8 | L | A | 0.0000 | |
| 9 | E | A | 0.0000 | |
| 10 | R | A | -2.4075 | |
| 11 | N | A | -1.9554 | |
| 12 | I | A | 0.0000 | |
| 13 | E | A | -1.1466 | |
| 14 | T | A | -1.0475 | |
| 15 | I | A | 0.0000 | |
| 16 | I | A | 0.0000 | |
| 17 | N | A | -0.5125 | |
| 18 | T | A | -0.6468 | |
| 19 | F | A | 0.0000 | |
| 20 | H | A | 0.0000 | |
| 21 | Q | A | -1.0825 | |
| 22 | Y | A | 0.0000 | |
| 23 | S | A | 0.0000 | |
| 24 | V | A | -0.7062 | |
| 25 | K | A | -1.3689 | |
| 26 | L | A | 0.1601 | |
| 27 | G | A | -0.6566 | |
| 28 | H | A | -1.2123 | |
| 29 | P | A | 0.0000 | |
| 30 | D | A | -1.3470 | |
| 31 | T | A | -1.3046 | |
| 32 | L | A | 0.0000 | |
| 33 | N | A | -2.0628 | |
| 34 | Q | A | -2.1173 | |
| 35 | G | A | -1.7109 | |
| 36 | E | A | -1.7021 | |
| 37 | F | A | 0.0000 | |
| 38 | K | A | -2.9048 | |
| 39 | E | A | -3.2108 | |
| 40 | L | A | 0.0000 | |
| 41 | V | A | 0.0000 | |
| 42 | R | A | -4.1425 | |
| 43 | K | A | -3.3768 | |
| 44 | D | A | 0.0000 | |
| 45 | L | A | 0.0000 | |
| 46 | Q | A | -2.7249 | |
| 47 | N | A | 0.0000 | |
| 48 | F | A | 0.0000 | |
| 49 | L | A | 0.0000 | |
| 50 | K | A | -2.8855 | |
| 51 | K | A | -3.1010 | |
| 52 | E | A | -3.2956 | |
| 53 | N | A | -4.0209 | |
| 54 | K | A | -3.8695 | |
| 55 | N | A | -3.4090 | |
| 56 | E | A | -3.5970 | |
| 57 | K | A | -3.2472 | |
| 58 | V | A | -2.2327 | |
| 59 | I | A | 0.0000 | |
| 60 | E | A | -3.1270 | |
| 61 | H | A | -2.7544 | |
| 62 | I | A | 0.0000 | |
| 63 | M | A | 0.0000 | |
| 64 | E | A | -3.6401 | |
| 65 | D | A | -3.0999 | |
| 66 | L | A | -1.8321 | |
| 67 | D | A | 0.0000 | |
| 68 | T | A | -1.8282 | |
| 69 | N | A | -2.4635 | |
| 70 | A | A | -2.4067 | |
| 71 | D | A | -3.1287 | |
| 72 | K | A | -3.4510 | |
| 73 | Q | A | -2.7146 | |
| 74 | L | A | 0.0000 | |
| 75 | S | A | -1.1527 | |
| 76 | F | A | 0.0000 | |
| 77 | E | A | -0.9160 | |
| 78 | E | A | 0.0000 | |
| 79 | F | A | 0.0000 | |
| 80 | I | A | 0.0000 | |
| 81 | M | A | -0.4915 | |
| 82 | L | A | 0.0000 | |
| 83 | M | A | 0.0000 | |
| 84 | A | A | 0.0000 | |
| 85 | R | A | -1.4846 | |
| 86 | L | A | 0.0000 | |
| 87 | T | A | 0.0000 | |
| 88 | W | A | -0.2260 | |
| 89 | A | A | -0.4413 | |
| 90 | S | A | 0.0000 | |
| 91 | H | A | 0.0000 | |
| 92 | E | A | -1.8792 | |
| 93 | K | A | -2.2498 | |
| 94 | M | A | -1.5806 | |
| 95 | H | A | -3.1099 | |
| 96 | E | A | -4.3471 | |
| 97 | G | A | -3.9737 | |
| 98 | D | A | -4.0726 | |
| 99 | E | A | -3.6231 | |
| 100 | G | A | -2.8115 | |
| 101 | P | A | -2.7756 | |
| 102 | G | A | -1.9054 | |
| 103 | H | A | -2.4390 | |
| 104 | H | A | -3.2798 | |
| 105 | H | A | -3.3903 | |
| 106 | K | A | -2.7661 | |
| 107 | P | A | -1.7215 | |
| 108 | G | A | -1.2780 | |
| 109 | L | A | 0.0000 | |
| 110 | G | A | -1.4932 | |
| 111 | E | A | 0.0000 | |
| 112 | G | A | -1.0667 | |
| 113 | T | A | -0.7534 | |
| 114 | P | A | -0.4248 | |
| 1 | M | B | 0.8541 | |
| 2 | T | B | 0.1213 | |
| 3 | S | B | -0.2891 | |
| 4 | K | B | -0.3258 | |
| 5 | M | B | -1.0563 | |
| 6 | S | B | -1.5644 | |
| 7 | Q | B | -2.0279 | |
| 8 | L | B | 0.0000 | |
| 9 | E | B | 0.0000 | |
| 10 | R | B | -2.3943 | |
| 11 | N | B | -1.9419 | |
| 12 | I | B | 0.0000 | |
| 13 | E | B | -1.1290 | |
| 14 | T | B | -1.0564 | |
| 15 | I | B | 0.0000 | |
| 16 | I | B | 0.0000 | |
| 17 | N | B | -0.5825 | |
| 18 | T | B | -0.6513 | |
| 19 | F | B | 0.0000 | |
| 20 | H | B | 0.0000 | |
| 21 | Q | B | -0.9885 | |
| 22 | Y | B | 0.0000 | |
| 23 | S | B | 0.0000 | |
| 24 | V | B | -0.6530 | |
| 25 | K | B | -1.3308 | |
| 26 | L | B | 0.1789 | |
| 27 | G | B | -0.6390 | |
| 28 | H | B | -1.2056 | |
| 29 | P | B | 0.0000 | |
| 30 | D | B | -1.3415 | |
| 31 | T | B | -1.3586 | |
| 32 | L | B | 0.0000 | |
| 33 | N | B | -2.2125 | |
| 34 | Q | B | -2.1967 | |
| 35 | G | B | -1.5795 | |
| 36 | E | B | -1.5131 | |
| 37 | F | B | 0.0000 | |
| 38 | K | B | -2.7651 | |
| 39 | E | B | -2.7216 | |
| 40 | L | B | 0.0000 | |
| 41 | V | B | 0.0000 | |
| 42 | R | B | -4.0772 | |
| 43 | K | B | -3.2279 | |
| 44 | D | B | 0.0000 | |
| 45 | L | B | 0.0000 | |
| 46 | Q | B | -3.1024 | |
| 47 | N | B | 0.0000 | |
| 48 | F | B | 0.0000 | |
| 49 | L | B | -1.8093 | |
| 50 | K | B | -3.0312 | |
| 51 | K | B | -3.1236 | |
| 52 | E | B | -3.3509 | |
| 53 | N | B | -4.0670 | |
| 54 | K | B | -3.8701 | |
| 55 | N | B | -3.3188 | |
| 56 | E | B | -3.9320 | |
| 57 | K | B | -3.3960 | |
| 58 | V | B | -2.3464 | |
| 59 | I | B | 0.0000 | |
| 60 | E | B | -3.3771 | |
| 61 | H | B | -2.9555 | |
| 62 | I | B | -1.9767 | |
| 63 | M | B | 0.0000 | |
| 64 | E | B | -4.3998 | |
| 65 | D | B | -3.4848 | |
| 66 | L | B | 0.0000 | |
| 67 | D | B | -3.1479 | |
| 68 | T | B | -2.1170 | |
| 69 | N | B | -2.6793 | |
| 70 | A | B | -2.7396 | |
| 71 | D | B | -3.4721 | |
| 72 | K | B | -4.1363 | |
| 73 | Q | B | -3.1193 | |
| 74 | L | B | 0.0000 | |
| 75 | S | B | -1.2373 | |
| 76 | F | B | 0.0000 | |
| 77 | E | B | -1.0401 | |
| 78 | E | B | 0.0000 | |
| 79 | F | B | 0.0000 | |
| 80 | I | B | 0.0000 | |
| 81 | M | B | -0.4934 | |
| 82 | L | B | 0.0000 | |
| 83 | M | B | 0.0000 | |
| 84 | A | B | 0.0000 | |
| 85 | R | B | -0.9412 | |
| 86 | L | B | 0.0000 | |
| 87 | T | B | 0.0000 | |
| 88 | W | B | -0.0180 | |
| 89 | A | B | -0.2703 | |
| 90 | S | B | 0.0000 | |
| 91 | H | B | 0.0000 | |
| 92 | E | B | -1.8604 | |
| 93 | K | B | -2.2419 | |
| 94 | M | B | -1.5760 | |
| 95 | H | B | -3.1211 | |
| 96 | E | B | -4.3594 | |
| 97 | G | B | -3.9949 | |
| 98 | D | B | -4.0809 | |
| 99 | E | B | -3.6250 | |
| 100 | G | B | -2.8127 | |
| 101 | P | B | -2.7803 | |
| 102 | G | B | -1.9113 | |
| 103 | H | B | -2.4530 | |
| 104 | H | B | -3.3169 | |
| 105 | H | B | -3.4613 | |
| 106 | K | B | -2.7519 | |
| 107 | P | B | -1.6397 | |
| 108 | G | B | 0.0000 | |
| 109 | L | B | 0.0000 | |
| 110 | G | B | -1.5120 | |
| 111 | E | B | 0.0000 | |
| 112 | G | B | -0.8495 | |
| 113 | T | B | -0.6961 | |
| 114 | P | B | -0.3493 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine