Project name: 6bae:A
Status: done
submitted: 2019-03-21 13:13:15, status changed: 2019-03-21 13:24:14
Settings
Chain sequence(s)
|
A: DIQMTQSPILLSASVGDRVTITCRASQDVNTAVAWYQQRRTNGSPRLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDEADYYCQQHYTTPPTFGAGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5939
-
Maximal score value
-
2.5005
-
Average score
-
-0.7281
-
Total score value
-
-155.824
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
A |
-2.3116 |
|
2 |
I |
A |
0.0000 |
|
3 |
Q |
A |
-1.8522 |
|
4 |
M |
A |
0.0000 |
|
5 |
T |
A |
-0.7122 |
|
6 |
Q |
A |
0.0000 |
|
7 |
S |
A |
0.2517 |
|
8 |
P |
A |
0.9508 |
|
9 |
I |
A |
2.0598 |
|
10 |
L |
A |
1.3604 |
|
11 |
L |
A |
0.4494 |
|
12 |
S |
A |
-0.5542 |
|
13 |
A |
A |
-0.9585 |
|
14 |
S |
A |
-0.8336 |
|
15 |
V |
A |
-0.0153 |
|
16 |
G |
A |
-0.6441 |
|
17 |
D |
A |
-1.6546 |
|
18 |
R |
A |
-2.2883 |
|
19 |
V |
A |
0.0000 |
|
20 |
T |
A |
-0.6140 |
|
21 |
I |
A |
0.0000 |
|
22 |
T |
A |
-0.5481 |
|
23 |
C |
A |
0.0000 |
|
24 |
R |
A |
-2.9448 |
|
25 |
A |
A |
0.0000 |
|
26 |
S |
A |
-2.3099 |
|
27 |
Q |
A |
-3.0451 |
|
28 |
D |
A |
-2.9466 |
|
29 |
V |
A |
0.0000 |
|
30 |
N |
A |
-2.0316 |
|
31 |
T |
A |
-1.0329 |
|
32 |
A |
A |
-0.4153 |
|
33 |
V |
A |
0.0000 |
|
34 |
A |
A |
0.8701 |
|
35 |
W |
A |
0.0000 |
|
36 |
Y |
A |
0.0272 |
|
37 |
Q |
A |
0.0000 |
|
38 |
Q |
A |
-1.4249 |
|
39 |
R |
A |
-1.8020 |
|
40 |
T |
A |
-1.4961 |
|
41 |
N |
A |
-1.6497 |
|
42 |
G |
A |
-1.5109 |
|
43 |
S |
A |
-1.1809 |
|
44 |
P |
A |
-1.0940 |
|
45 |
R |
A |
-1.3383 |
|
46 |
L |
A |
-0.0217 |
|
47 |
L |
A |
0.0000 |
|
48 |
I |
A |
0.0000 |
|
49 |
Y |
A |
1.6695 |
|
50 |
S |
A |
0.4820 |
|
51 |
A |
A |
0.0000 |
|
52 |
S |
A |
0.9169 |
|
53 |
F |
A |
2.5005 |
|
54 |
L |
A |
1.8581 |
|
55 |
Y |
A |
1.4751 |
|
56 |
S |
A |
0.3755 |
|
57 |
G |
A |
-0.2738 |
|
58 |
V |
A |
0.0000 |
|
59 |
P |
A |
-0.2797 |
|
60 |
S |
A |
-0.3517 |
|
61 |
R |
A |
-0.7652 |
|
62 |
F |
A |
0.0000 |
|
63 |
S |
A |
0.0671 |
|
64 |
G |
A |
0.1164 |
|
65 |
S |
A |
-0.5677 |
|
66 |
R |
A |
-1.7635 |
|
67 |
S |
A |
-1.4628 |
|
68 |
G |
A |
-1.9576 |
|
69 |
T |
A |
-2.4239 |
|
70 |
D |
A |
-2.2372 |
|
71 |
F |
A |
0.0000 |
|
72 |
T |
A |
-0.8034 |
|
73 |
L |
A |
0.0000 |
|
74 |
T |
A |
-0.6201 |
|
75 |
I |
A |
0.0000 |
|
76 |
S |
A |
-1.3879 |
|
77 |
S |
A |
-1.1128 |
|
78 |
L |
A |
0.0000 |
|
79 |
Q |
A |
-0.7185 |
|
80 |
P |
A |
-1.6175 |
|
81 |
E |
A |
-2.1159 |
|
82 |
D |
A |
0.0000 |
|
83 |
E |
A |
0.0000 |
|
84 |
A |
A |
0.0000 |
|
85 |
D |
A |
-0.7203 |
|
86 |
Y |
A |
0.0000 |
|
87 |
Y |
A |
0.2917 |
|
88 |
C |
A |
0.0000 |
|
89 |
Q |
A |
0.0000 |
|
90 |
Q |
A |
0.0000 |
|
91 |
H |
A |
-0.3847 |
|
92 |
Y |
A |
0.1974 |
|
93 |
T |
A |
-0.1593 |
|
94 |
T |
A |
-0.5127 |
|
95 |
P |
A |
-0.4966 |
|
96 |
P |
A |
-0.3516 |
|
97 |
T |
A |
0.1628 |
|
98 |
F |
A |
1.5515 |
|
99 |
G |
A |
0.4336 |
|
100 |
A |
A |
0.5392 |
|
101 |
G |
A |
0.0000 |
|
102 |
T |
A |
0.0000 |
|
103 |
K |
A |
-0.6593 |
|
104 |
V |
A |
0.0000 |
|
105 |
E |
A |
-1.1272 |
|
106 |
I |
A |
0.0000 |
|
107 |
K |
A |
-1.3998 |
|
108 |
R |
A |
-0.9656 |
|
109 |
T |
A |
-0.2114 |
|
110 |
V |
A |
0.1525 |
|
111 |
A |
A |
0.0131 |
|
112 |
A |
A |
-0.2087 |
|
113 |
P |
A |
0.0000 |
|
114 |
S |
A |
-0.0505 |
|
115 |
V |
A |
0.0000 |
|
116 |
F |
A |
1.4349 |
|
117 |
I |
A |
1.3387 |
|
118 |
F |
A |
1.4789 |
|
119 |
P |
A |
-0.0003 |
|
120 |
P |
A |
0.0000 |
|
121 |
S |
A |
-1.7910 |
|
122 |
D |
A |
-3.2625 |
|
123 |
E |
A |
-3.4352 |
|
124 |
Q |
A |
-2.5751 |
|
125 |
L |
A |
-2.5956 |
|
126 |
K |
A |
-3.0607 |
|
127 |
S |
A |
-1.9410 |
|
128 |
G |
A |
-1.2778 |
|
129 |
T |
A |
-0.9592 |
|
130 |
A |
A |
0.0000 |
|
131 |
S |
A |
0.0349 |
|
132 |
V |
A |
0.0000 |
|
133 |
V |
A |
0.7735 |
|
134 |
C |
A |
0.0000 |
|
135 |
L |
A |
0.5944 |
|
136 |
L |
A |
0.0000 |
|
137 |
N |
A |
-0.5044 |
|
138 |
N |
A |
-1.3205 |
|
139 |
F |
A |
0.0000 |
|
140 |
Y |
A |
-1.2744 |
|
141 |
P |
A |
-1.7931 |
|
142 |
R |
A |
-3.1457 |
|
143 |
E |
A |
-3.2603 |
|
144 |
A |
A |
-2.4081 |
|
145 |
K |
A |
-2.7104 |
|
146 |
V |
A |
0.0000 |
|
147 |
Q |
A |
-1.3954 |
|
148 |
W |
A |
0.0000 |
|
149 |
K |
A |
-0.8542 |
|
150 |
V |
A |
0.0000 |
|
151 |
D |
A |
-1.9725 |
|
152 |
N |
A |
-1.5654 |
|
153 |
A |
A |
-0.2923 |
|
154 |
L |
A |
0.5565 |
|
155 |
Q |
A |
-0.5947 |
|
156 |
S |
A |
-0.8013 |
|
157 |
G |
A |
-1.4411 |
|
158 |
N |
A |
-1.8532 |
|
159 |
S |
A |
-1.9176 |
|
160 |
Q |
A |
-2.4028 |
|
161 |
E |
A |
-2.2063 |
|
162 |
S |
A |
-1.0629 |
|
163 |
V |
A |
-0.7391 |
|
164 |
T |
A |
-1.3122 |
|
165 |
E |
A |
-2.4141 |
|
166 |
Q |
A |
0.0000 |
|
167 |
D |
A |
-2.7611 |
|
168 |
S |
A |
-2.4099 |
|
169 |
K |
A |
-2.6886 |
|
170 |
D |
A |
-1.9573 |
|
171 |
S |
A |
0.0000 |
|
172 |
T |
A |
0.0000 |
|
173 |
Y |
A |
0.0000 |
|
174 |
S |
A |
-1.0558 |
|
175 |
L |
A |
0.0000 |
|
176 |
S |
A |
-0.4067 |
|
177 |
S |
A |
0.0000 |
|
178 |
T |
A |
-0.6845 |
|
179 |
L |
A |
0.0000 |
|
180 |
T |
A |
-0.7278 |
|
181 |
L |
A |
-0.7965 |
|
182 |
S |
A |
-1.1705 |
|
183 |
K |
A |
-1.9926 |
|
184 |
A |
A |
-1.7752 |
|
185 |
D |
A |
-2.4424 |
|
186 |
Y |
A |
0.0000 |
|
187 |
E |
A |
-3.4152 |
|
188 |
K |
A |
-3.5939 |
|
189 |
H |
A |
-3.0378 |
|
190 |
K |
A |
-3.3659 |
|
191 |
V |
A |
-1.6372 |
|
192 |
Y |
A |
0.0000 |
|
193 |
A |
A |
0.0000 |
|
194 |
C |
A |
0.0000 |
|
195 |
E |
A |
-1.2680 |
|
196 |
V |
A |
0.0000 |
|
197 |
T |
A |
-1.3986 |
|
198 |
H |
A |
0.0000 |
|
199 |
Q |
A |
-1.7931 |
|
200 |
G |
A |
-0.4482 |
|
201 |
L |
A |
-0.2232 |
|
202 |
S |
A |
-0.4428 |
|
203 |
S |
A |
-0.4674 |
|
204 |
P |
A |
-0.7356 |
|
205 |
V |
A |
-0.2191 |
|
206 |
T |
A |
-0.5834 |
|
207 |
K |
A |
-0.4659 |
|
208 |
S |
A |
-0.4109 |
|
209 |
F |
A |
0.0000 |
|
210 |
N |
A |
-2.0283 |
|
211 |
R |
A |
-2.6148 |
|
212 |
G |
A |
-2.0823 |
|
213 |
E |
A |
-2.2122 |
|
214 |
C |
A |
-0.4167 |
|