Project name: DI1000160

Chain sequence(s)	S: FGRTGLPDLSSMTEEEQIAYAMQMSLQGAEFG; U: MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVPIRDYRIDEKNFVVVMVTK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.2434
• Maximal score value: 1.3331
• Average score: -1.0554
• Total score value: -116.091

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
270	F	S	1.3331
271	G	S	-0.1938
272	R	S	-1.3831
273	T	S	-0.7407
274	G	S	-1.1445
275	L	S	-0.5225
276	P	S	-0.4679
277	D	S	-1.3177
278	L	S	0.0000
279	S	S	-0.4461
280	S	S	-1.0636
281	M	S	-0.7627
282	T	S	0.0000
283	E	S	-2.0955
284	E	S	-2.1119
285	E	S	-1.0358
286	Q	S	0.0000
287	I	S	-0.0545
288	A	S	-0.1850
289	Y	S	-0.1983
290	A	S	0.0000
291	M	S	0.3424
292	Q	S	-0.6796
293	M	S	-0.4515
294	S	S	0.0000
295	L	S	-0.6829
296	Q	S	-1.1513
297	G	S	-0.8219
298	A	S	-0.7344
299	E	S	-1.1863
300	F	S	0.7719
301	G	S	-0.2329
1	M	U	0.8734
2	A	U	-0.1547
3	V	U	-0.3262
4	T	U	-1.3812
5	I	U	0.0000
6	T	U	0.0000
7	L	U	0.0000
8	K	U	-0.9435
9	T	U	0.0000
10	L	U	0.0000
11	Q	U	-1.2870
12	Q	U	-1.8263
13	Q	U	-1.7437
14	T	U	-1.0667
15	F	U	-1.1642
16	K	U	-2.5169
17	I	U	0.0000
18	R	U	-2.1533
19	M	U	0.0000
20	E	U	-1.9499
21	P	U	-2.9005
22	D	U	-3.2712
23	E	U	-2.8607
24	T	U	-2.3157
25	V	U	0.0000
26	K	U	-1.9482
27	V	U	-1.6210
28	L	U	0.0000
29	K	U	0.0000
30	E	U	-2.7491
31	K	U	-2.5570
32	I	U	0.0000
33	E	U	0.0000
34	A	U	-2.2511
35	E	U	-2.5501
36	K	U	0.0000
37	G	U	-2.2608
38	R	U	-3.3181
39	D	U	-2.9515
40	A	U	0.0000
41	F	U	0.0000
42	P	U	-1.8040
43	V	U	-1.4636
44	A	U	-1.0951
45	G	U	-1.0929
46	Q	U	0.0000
47	K	U	-0.6430
48	L	U	0.0000
49	I	U	0.0000
50	Y	U	-0.8842
51	A	U	-1.0166
52	G	U	-1.0463
53	K	U	-1.3081
54	I	U	-0.0271
55	L	U	0.0000
56	S	U	-0.9951
57	D	U	-1.6583
58	D	U	-2.1240
59	V	U	-1.6976
60	P	U	-2.8001
61	I	U	0.0000
62	R	U	-4.2434
63	D	U	-3.5196
64	Y	U	-2.4589
65	R	U	-3.2412
66	I	U	0.0000
67	D	U	-2.3167
68	E	U	-3.1544
69	K	U	-2.9281
70	N	U	-2.2847
71	F	U	-1.2958
72	V	U	0.0000
73	V	U	0.0000
74	V	U	0.0000
75	M	U	0.0000
76	V	U	0.0000
77	T	U	-1.8459
78	K	U	-2.7341